Statin and NSAID use and prostate cancer risk.

abstract：PURPOSE:Medicaid programs are concerned about inappropriate, potentially hazardous, and costly off-label use of second-generation antipsychotics (SGAs). Several states are exploring policies aimed at managing low-dose quetiapine, commonly prescribed for off-label conditions. This study aimed to characterize longitudina...

journal_title：Pharmacoepidemiology and drug safety

authors： Hartung DM,Zerzan J,Yamashita T,Tong S,Morden NE,Libby AM

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To examine and compare the quality of drug prescribing for older patients in nursing homes and home nursing services. METHODS:Cross-sectional study comprising 11,254 patients aged ≥ 65 years in nursing homes (n = 2986) and home nursing services (n = 8268). Potentially inappropriate medications were identified ...

journal_title：Pharmacoepidemiology and drug safety

authors： Halvorsen KH,Granas AG,Engeland A,Ruths S

更新日期：2012-09-01 00:00:00

abstract：:Dr. Walker asserts that a hypothesis always can be tested using the same data source that generated the data if the test data are independent of the data generating the hypothesis. One way to do this is to use part of the totality of data to generate the hypothesis and the other to test the hypothesis. The validity of...

journal_title：Pharmacoepidemiology and drug safety

authors： Gould AL

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:The purpose of this study is to characterise how Type 2 Diabetes Mellitus (T2DM) is treated in England and Wales and whether this adheres to 2009 National Institute for Health and Care Excellence (NICE) guidance on management of T2DM. METHODS:Data for T2DM patients aged 18+ years prescribed at least one anti-d...

journal_title：Pharmacoepidemiology and drug safety

authors： Datta-Nemdharry P,Thomson A,Beynon J,Donegan K

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Discontinuing low-dose acetylsalicylic acid (ASA) therapy after upper gastrointestinal bleeding (UGIB) may increase the risk of cardiovascular-related death. Our aim was to compare mortality in UK primary care patients who discontinue ASA after UGIB with that in patients who continue therapy. METHODS:ASA users...

journal_title：Pharmacoepidemiology and drug safety

authors： González-Pérez A,Sáez ME,Johansson S,Nagy P,García Rodríguez LA

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:A recent regulatory warning and case reports have described the development of muscle complications with the use of 5-α reductase inhibitors (5ARIs). We wished to determine if there was a link between rhabdomyolysis and 5ARI usage. METHODS:We used a matched cohort design and linked administrative data from the...

journal_title：Pharmacoepidemiology and drug safety

authors： Welk B,McArthur E,Ordon M,Dirk J,Dixon S,Garg AX

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:We conducted a nested case-control study to evaluate the association between risk of cancer and mirtazapine use in depression patients in Taiwan. METHODS:We obtained data from the Taiwan National Health Insurance Research Database to conduct a population-based nested case-control study. The study cohort includ...

journal_title：Pharmacoepidemiology and drug safety

authors： Sun LM,Lin MC,Liang JA,Chang YJ,Chang SN,Sung FC,Muo CH,Kao CH

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To estimate the incidence trend and outcome of paracetamol poisoning, in relation to increased availability of paracetamol from non-pharmacy outlets in 2009. METHOD:Patients' serum paracetamol results over 14 years (2000-2013) from 20 (out of 21) regions in Sweden were linked to national registers of hospital ...

journal_title：Pharmacoepidemiology and drug safety

authors： Gedeborg R,Svennblad B,Holm L,Sjögren H,Bardage C,Personne M,Sjöberg G,Feltelius N,Zethelius B

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:Bias analysis methods are developed for application to 2 x 2 tables, which may be crude or stratified data. Methods for application to associations adjusted for multiple covariates, such as associations from regression modeling, are rarely seen. We have developed probabilistic methods to evaluate bias from dise...

journal_title：Pharmacoepidemiology and drug safety

authors： Lash TL,Schmidt M,Jensen AØ,Engebjerg MC

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:A case-control study is the most powerful design to test the risk of specific congenital malformations associated with a specific drug. However, malformation registries often lack non-malformed controls. For the Dutch EUROCAT, we collected a non-malformed control group: the 'Healthy Pregnant'. The aim of this s...

journal_title：Pharmacoepidemiology and drug safety

authors： Jentink J,Zetstra-van der Woude AP,Bos J,de Jong-van den Berg LT

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:This study aimed to examine the effect of antidepressant use on persistence with newly initiated oral antidiabetic medicines in older people. METHODS:A retrospective study of administrative claims data from the Australian Government Department of Veterans' Affairs, from 1 July 2000 to 30 June 2008 of new users...

journal_title：Pharmacoepidemiology and drug safety

authors： Caughey GE,Preiss AK,Vitry AI,Gilbert AL,Ryan P,Shakib S,Esterman A,McDermott RA,Roughead EE

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:Oral morphine is the first-choice opioid for moderate to severe cancer pain. Transdermal fentanyl is an alternative in patients with stable requirements of high-potency opioids (HPO) or if drugs cannot be taken orally. Drug regulatory authorities have issued several alerts to use transdermal fentanyl only for c...

journal_title：Pharmacoepidemiology and drug safety

authors： Garbe E,Jobski K,Schmid U

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:Administration of pegylated interferon-alpha (IFN-alpha) and ribavirin in adults with chronic hepatitis C (CHC) is a recommended therapeutic standard. Nevertheless, this therapeutic regimen rises numerous controversies. The aim of this study was to analyze adverse effects during the treatment with pegylated IFN...

journal_title：Pharmacoepidemiology and drug safety

authors： Kowala-Piaskowska A,Mozer-Lisewska I,Figlerowicz M,Słuzewski W

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:In pharmacoepidemiology, one of the main concerns is analysis of drug exposure time. However, in real-life settings, patient's behavior is complex and characterized by drug exposure dynamics. Multi-state models allow assessing the probabilities of various patterns, instead of just continuous use and/or disconti...

journal_title：Pharmacoepidemiology and drug safety

authors： Boucherie Q,Pauly V,Frauger E,Thirion X,Pradel V,Micallef J

更新日期：2015-09-01 00:00:00

abstract：:Purpose - The objective of this study was an evaluation of the sensitivity of findings of the relationship between oral corticosteroid use and the risk of fracture. We found in earlier work that the risk of fracture was significantly higher during oral corticosteroid treatment, with increases of 61% in hip and 160% in...

journal_title：Pharmacoepidemiology and drug safety

authors： Van Staa TP,Abenhaim L,Cooper C,Zhang B,Leufkens HG

更新日期：2000-09-01 00:00:00

abstract：PURPOSE:The role of administrative databases for research on drug safety during pregnancy can be limited by their inaccurate assessment of the timing of exposure, as the gestational age at birth is typically unavailable. Therefore, we sought to develop and validate algorithms to estimate the gestational age at birth us...

journal_title：Pharmacoepidemiology and drug safety

authors： Margulis AV,Setoguchi S,Mittleman MA,Glynn RJ,Dormuth CR,Hernández-Díaz S

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:The purpose of this paper is to describe the infrastructure of the total joint replacement registry of a large integrated healthcare system's and emphasize challenges associated with orthopedic device classification and evaluation. METHODS:Using a large integrated healthcare system innovative infrastructure in...

journal_title：Pharmacoepidemiology and drug safety

authors： Paxton EW,Ake CF,Inacio MC,Khatod M,Marinac-Dabic D,Sedrakyan A

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:This study compared the effectiveness of rosuvastatin (RSV) to other statins prescribed in clinical practice in prevention of cardiovascular (CV) events. METHODS:This longitudinal inception cohort study, using Thomson Healthcare's MarketScan databases, included patients aged > or = 18 starting statin therapy d...

journal_title：Pharmacoepidemiology and drug safety

authors： Motsko SP,Russmann S,Ming EE,Singh VP,Vendiola RM,Jones JK

更新日期：2009-12-01 00:00:00

abstract：:We review the concept of time-dependent confounding by using the example in paper "Comparative effectiveness of individual angiotensin receptor blockers on risk of mortality in patients with chronic heart failure" by Desai et al. and illustrate how to adjust for it by using inverse probability of treatment weighting t...

journal_title：Pharmacoepidemiology and drug safety

authors： Yang W,Joffe MM

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Following approval in the EU in 2002 and the USA in 2003, an Intensive Safety Surveillance Scheme (IS(3) ) was initiated to educate prescribers on the appropriate use of miglustat for the treatment of type I Gaucher disease (GD1), and to actively solicit safety-relevant information. This report summarises da...

journal_title：Pharmacoepidemiology and drug safety

authors： Brand M,Muller A,Alsop J,van Schaik IN,Bembi B,Hughes D

更新日期：2015-03-01 00:00:00

abstract：PURPOSES:To describe the kind of the difficulties encountered when seeking research governance approval for a nationwide public health and genetic study-the Drug-Induced Arrhythmia Risk Evaluation study-in England. METHODS:Description of the processes followed when seeking research governance approval for the Drug-Ind...

journal_title：Pharmacoepidemiology and drug safety

authors： Boshier A,Shakir SA,Telfer P,Behr E,Pakrashi T,Camm AJ

更新日期：2005-06-01 00:00:00

abstract：PURPOSE:To assess the reason for the relative high risk of local complications for women following cardiac catheterization by evaluating the associations between gender, sheath size, and local adverse outcomes following cardiac catheterization. METHODS:The data used in this study were obtained from a portion of the Am...

journal_title：Pharmacoepidemiology and drug safety

authors： Tavris DR,Gallauresi BA,Dey S,Brindis R,Mitchel K

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:To assess the prevalence and potential indications of PDE5 inhibitor use among pregnant and reproductive-age women in the United States. METHODS:We identified women 15 to 50 years with a livebirth from January 2001 through March 2018 in Sentinel Database. We assessed the prevalence of PDE5 inhibitor use prior ...

journal_title：Pharmacoepidemiology and drug safety

authors： Liu W,Menzin TJ,Woods CM,Haug NR,Li J,Mathew JA,Nguyen CP,Chai GP,Moeny DG,Shinde M

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:(1) To identify factors associated with the choice among the three atypical antipsychotics available in France (amisulpride, olanzapine, risperidone) and the typical antipsychotic of reference: (haloperidol), (2) to compare psychotropic co-prescription rates according to antipsychotic. METHODS:All antipsychoti...

journal_title：Pharmacoepidemiology and drug safety

authors： Gasquet I,Gury C,Tcherny-Lessenot S,Quesnot A,Gaudebout P

更新日期：2005-11-01 00:00:00

abstract：PURPOSE:To determine prescribing patterns by general physicians working in primary care (GPs) in Iran for the elderly and the prevalence of inappropriate prescribing. METHODS:We collected information about prescribed medicines for 10% of patients in primary care aged 65 years or above in six cities in one province dur...

journal_title：Pharmacoepidemiology and drug safety

authors： Ghadimi H,Esmaily HM,Wahlstrom R

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:This study quantified the overall merit of adjunctive aripiprazole in major depressive disorder (MDD). METHODS:Global benefit-risk (GBR) analysis quantified the benefit and risk differences between adjunctive aripiprazole and antidepressant (ADT) monotherapy. Three hundred and fifty six patients receiving AD...

journal_title：Pharmacoepidemiology and drug safety

authors： Wisniewski SR,Chen CC,Kim E,Kan HJ,Guo Z,Carlson BX,Tran QV,Pikalov A

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:Administrative claim databases are increasingly being used to study the safety of medication exposures during pregnancy. These studies are restricted to live births due to a reliance on algorithms for estimating gestational age that are based on codes associated with live delivery. Conditioning on live birth ma...

journal_title：Pharmacoepidemiology and drug safety

authors： Suarez EA,Landi SN,Conover MM,Jonsson Funk M

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To compare the frequency of adverse drug reactions (ADRs) recorded by doctors with perceived ADRs reported by patients during hospitalization and post-discharge and to compare both to formal reporting in Thailand. SETTING:Tertiary teaching hospital, North-East Thailand. METHODS:Over a 6-month period doctors w...

journal_title：Pharmacoepidemiology and drug safety

authors： Jarernsiripornkul N,Kakaew W,Loalukkana W,Krska J

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:UK primary care databases are frequently used in observational studies with cancer outcomes. We aimed to systematically review methods used by such studies to identify and validate incident cancers of the breast, colorectum, and prostate. METHODS:Medline and Embase (1980-2013) were searched for UK primary care...

journal_title：Pharmacoepidemiology and drug safety

authors： Rañopa M,Douglas I,van Staa T,Smeeth L,Klungel O,Reynolds R,Bhaskaran K

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To develop and test an algorithm that translates total dose and daily regimen, inputted as 'free text' on a prescription, into numerical values to calculate the prescribed treatment duration. METHOD:The algorithm was developed using antibiotic prescriptions (n = 711,714) from multiple primary care computer sys...

journal_title：Pharmacoepidemiology and drug safety

authors： Brooks CJ,Lyons RA,Jones KH,Hutton AJ,Walker R,Evans KA,Lloyd K,Ford DV

更新日期：2010-09-01 00:00:00