Methods to apply probabilistic bias analysis to summary estimates of association.

abstract：PURPOSE:To determine patterns of United Arab Emirates (UAE) citizen herbal medicine taking. METHODS:Questionnaire survey of UAE citizens attending a primary healthcare clinic in Abu Dhabi. RESULTS:Three hundred and thirty surveys were analysed. Seventy-six per cent (250/330) had previously used herbal products, and o...

journal_title：Pharmacoepidemiology and drug safety

authors： AlBraik FA,Rutter PM,Brown D

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:Recent public health safety issues involving medical devices have led to a growing demand to improve the current passive-reactive postmarket surveillance (PMS) system. Various European Union (EU) national competent authorities have started to focus on strengthening the postmarket risk evaluation. As a consequen...

journal_title：Pharmacoepidemiology and drug safety

authors： Pane J,Francisca RDC,Verhamme KMC,Orozco M,Viroux H,Rebollo I,Sturkenboom MCJM

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:Bayesian hierarchical models (BHMs) have been used to identify adverse drug reactions, allowing information sharing amongst adverse reactions and drugs expected to have similar properties. This study evaluated the use of BHMs in the routine signal detection analyses of potential first-trimester teratogens, wher...

journal_title：Pharmacoepidemiology and drug safety

authors： Cavadino A,Prieto-Merino D,Morris JK

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:We present a new population-based pharmacoepidemiological (PE) database obtained from statutory health insurances (SHIs) that is able to generate signals, to monitor prescribed drugs and to describe drug utilisation. We discuss methodological features of the database and we assess to which degree this database ...

journal_title：Pharmacoepidemiology and drug safety

authors： Pigeot I,Ahrens W

更新日期：2008-03-01 00:00:00

abstract：PURPOSE:The goal of this study is to summarize trends in rates of adverse events attributable to acetaminophen use, including hepatotoxicity and mortality. METHODS:A comprehensive analysis of data from three national surveillance systems estimated rates of acetaminophen-related events identified in different settings,...

journal_title：Pharmacoepidemiology and drug safety

authors： Major JM,Zhou EH,Wong HL,Trinidad JP,Pham TM,Mehta H,Ding Y,Staffa JA,Iyasu S,Wang C,Willy ME

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:The Vaccine Safety Datalink (VSD) Project conducts near real-time vaccine safety surveillance using sequential analytic methods. Timely surveillance is critical in identifying potential safety problems and preventing additional exposure before most vaccines are administered. For vaccines that are administered d...

journal_title：Pharmacoepidemiology and drug safety

authors： Greene SK,Kulldorff M,Yin R,Yih WK,Lieu TA,Weintraub ES,Lee GM

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:The aims of this study are to examine the validity of diagnostic codes for psoriatic arthritis in The Health Improvement Network (THIN) and to examine the agreement between General Practitioner (GP) report and prescription records for disease modifying antirheumatic drugs (DMARDs). METHODS:Questionnaires were ...

journal_title：Pharmacoepidemiology and drug safety

authors： Ogdie A,Alehashemi S,Love TJ,Jiang Y,Haynes K,Hennessy S,Choi H,Gelfand JM

更新日期：2014-09-01 00:00:00

abstract：:We review the concept of time-dependent confounding by using the example in paper "Comparative effectiveness of individual angiotensin receptor blockers on risk of mortality in patients with chronic heart failure" by Desai et al. and illustrate how to adjust for it by using inverse probability of treatment weighting t...

journal_title：Pharmacoepidemiology and drug safety

authors： Yang W,Joffe MM

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:Determining the nature of the relationship between cumulative duration of exposure to an agent and the hazard of an adverse outcome is an important issue in environmental and occupational epidemiology, public health and clinical medicine. The Cox proportional hazards regression model can incorporate time-depend...

journal_title：Pharmacoepidemiology and drug safety

authors： Austin PC,Park-Wyllie LY,Juurlink DN

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:Proton pump inhibitor (PPI) may suppress adrenal cortical steroid synthesis and release, thereby leading to electrolyte disturbances. Both hyponatremia and hyperkalemia in the setting of PPI therapy have been documented in case reports. The objective of this study was to examine the association between serum po...

journal_title：Pharmacoepidemiology and drug safety

authors： Gau JT,Heh V,Acharya U,Yang YX,Kao TC

更新日期：2009-09-01 00:00:00

abstract：:Adverse drug reaction surveillance conducted by the US Federal Food and Drug Administration (FDA) is important for detecting new safety information about pharmaceuticals. FDA has sought to stimulate reporting of reactions by practitioners and manufacturers. Over the five years from 1989 to 1993, reporting more than do...

journal_title：Pharmacoepidemiology and drug safety

authors： Faich GA

更新日期：1996-11-01 00:00:00

abstract：PURPOSE:To determine prescribing patterns by general physicians working in primary care (GPs) in Iran for the elderly and the prevalence of inappropriate prescribing. METHODS:We collected information about prescribed medicines for 10% of patients in primary care aged 65 years or above in six cities in one province dur...

journal_title：Pharmacoepidemiology and drug safety

authors： Ghadimi H,Esmaily HM,Wahlstrom R

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:Quantitative benefit-risk (B-R) assessments are used to characterize treatment by combining key benefits and risks into a single metric but have historically been done for the "average" patient. Our aim was to conduct an individualized assessment for the oral antiplatelet vorapaxar by combining trial and real-w...

journal_title：Pharmacoepidemiology and drug safety

authors： Pinto CA,Tervonen T,Marsh K,Lambrelli D,Schultze A,Tershakovec A,Hyacinthe J,Prawitz T,Hammad TA

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:To estimate 1-year prevalence, 1-year incidence and indication of use of antidepressant (AD) drug treatment in general practice of Southern Italy during the years 2003-2004. METHODS:Among 142,346 individuals registered in the lists of 119 general practitioners of Southern Italy, we identified users of differen...

journal_title：Pharmacoepidemiology and drug safety

authors： Trifirò G,Barbui C,Spina E,Moretti S,Tari M,Alacqua M,Caputi AP,UVEC group.,Arcoraci V

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:To evaluate the internet way of feedback to prescribing physicians, providing data on antimicrobial use and to assess the applicability of the DU90% (i.e. Drug Utilisation 90%--the number of drugs accounting for 90% of the volume of usage in defined daily doses, (DDDs)) methodology in the hospital setting. MET...

journal_title：Pharmacoepidemiology and drug safety

authors： Bergman U,Risinggård H,Vlahović-Palcevski V,Ericsson O

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:To enhance automated methods for accurately identifying opioid-related overdoses and classifying types of overdose using electronic health record (EHR) databases. METHODS:We developed a natural language processing (NLP) software application to code clinical text documentation of overdose, including identificat...

journal_title：Pharmacoepidemiology and drug safety

authors： Hazlehurst B,Green CA,Perrin NA,Brandes J,Carrell DS,Baer A,DeVeaugh-Geiss A,Coplan PM

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To evaluate whether the risk of coronary heart disease (CHD) differs among adult diabetic patients treated with thiazolidinediones (TZDs) and similar patients treated with combined oral metformin and sulfonylurea (M + S) therapy. METHODS:We conducted a retrospective cohort study involving 25 140 diabetic patie...

journal_title：Pharmacoepidemiology and drug safety

authors： Johannes CB,Koro CE,Quinn SG,Cutone JA,Seeger JD

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:Nonsteroidal anti-inflammatory drugs (NSAIDs) may be associated with severe renal complications, including acute renal failure, reduced glomerular filtration rate and interstitial nephritis. Caution against NSAIDs is therefore recommended in advanced chronic kidney disease. In this study, we examined NSAID use,...

journal_title：Pharmacoepidemiology and drug safety

authors： Kristensen SL,Fosbøl EL,Kamper AL,Køber L,Hommel K,Lamberts M,Abildstrøm SZ,Blicher TM,Torp-Pedersen C,Gislason GH

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:This study quantifies the incidence of liver enzyme abnormalities in the general population of central Massachusetts. METHODS:Computerized data files from a health maintenance organization were used to ascertain potential subjects during the study period of 1 July 1992-30 June 1993. Medical records and labo...

journal_title：Pharmacoepidemiology and drug safety

authors： Duh MS,Walker AM,Kronlund KH Jr

更新日期：1999-07-01 00:00:00

abstract：PURPOSE:Clinical trials of olmesartan for prevention of progression of renal disease in patients with diabetes showed renal protection but an unexpected imbalance in cardiac deaths. The US Food and Drug Administration requested from the manufacturer a cohort study of olmesartan, other angiotensin-receptor blockers (ARB...

journal_title：Pharmacoepidemiology and drug safety

authors： Walker AM,Liang C,Clifford CR,Parker C,Feldman A

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:To review conceptual issues regarding confounding by indication in the context of studies of calcium channel blockers (CCBs). METHODS:Review of literature, with special attention to two articles in the current issue. RESULTS:Conflicting arguments about the presence of uncontrollable confounding by indication ...

journal_title：Pharmacoepidemiology and drug safety

authors： Joffe MM

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:In post-marketing drug safety surveillance, data mining can potentially detect rare but serious adverse events. Assessing an entire collection of drug-event pairs is traditionally performed on a predefined level of granularity. It is unknown a priori whether a drug causes a very specific or a set of related adv...

journal_title：Pharmacoepidemiology and drug safety

authors： Kulldorff M,Dashevsky I,Avery TR,Chan AK,Davis RL,Graham D,Platt R,Andrade SE,Boudreau D,Gunter MJ,Herrinton LJ,Pawloski PA,Raebel MA,Roblin D,Brown JS

更新日期：2013-05-01 00:00:00

abstract：AIM:To determine the appropriate size of risk windows in both exposed and unexposed sub-cohorts. METHOD:Data was taken from a previous study of upper gastrointestinal haemorrhage and perforation. The length of each prescription for NSAIDs was estimated. The risk was calculated for the duration of a prescription plus i...

journal_title：Pharmacoepidemiology and drug safety

authors： McMahon AD,Evans JM,McGilchrist MM,McDevitt DG,MacDonald TM

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:Medicaid programs are concerned about inappropriate, potentially hazardous, and costly off-label use of second-generation antipsychotics (SGAs). Several states are exploring policies aimed at managing low-dose quetiapine, commonly prescribed for off-label conditions. This study aimed to characterize longitudina...

journal_title：Pharmacoepidemiology and drug safety

authors： Hartung DM,Zerzan J,Yamashita T,Tong S,Morden NE,Libby AM

更新日期：2014-01-01 00:00:00

abstract：:Erythromycin is commonly used to treat simple community-acquired pneumonia. We measured the prolongation in QT(c) intervals in EKGs associated with intravenous erythromycin administration among patients hospitalized for simple pneumonia (DRGs 89 and 90). We reviewed the medical records of 50 patients who received at l...

journal_title：Pharmacoepidemiology and drug safety

authors： Freeman J,Platt R

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:Drug-induced liver injury (DILI) is one of the primary targets for pharmacovigilance using medical information databases (MIDs). Because of diagnostic complexity, a standardized method for identifying DILI using MIDs has not yet been established. We applied the Digestive Disease Week Japan 2004 (DDW-J) scale, a...

journal_title：Pharmacoepidemiology and drug safety

authors： Hanatani T,Sai K,Tohkin M,Segawa K,Kimura M,Hori K,Kawakami J,Saito Y

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:During the past two decades, many novel immunosuppressive drugs have been approved for transplant recipients. Trends in the use of maintenance immunosuppressants after liver transplantation in Asia are unclear. Thus, we aimed to analyze the prescription trends in maintenance immunosuppressive drugs among liver ...

journal_title：Pharmacoepidemiology and drug safety

authors： Huang YY,Hsu CC,Chou CL,Loong CC,Wu MS,Chou YC

更新日期：2016-06-01 00:00:00

abstract：UNLABELLED:Computerized hospital databases are used for clinical and economic research. In France, the hospital administrative database, Programme de médicalisation des systèmes d'information (PMSI), could be an interesting means for identifying cases of abuse and dependence in hospitals. PURPOSE:To assess the capabil...

journal_title：Pharmacoepidemiology and drug safety

authors： Daveluy A,Miremont-Salamé G,Kostrzewa A,Couret A,Lacoin L,Lecomte C,Moore N,Gilleron V,Haramburu F

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To determine the risk factors and rate of medication administration error (MAE) alerts by analyzing large-scale medication administration data and related error logs automatically recorded in a closed-loop medication administration system using radio-frequency identification and barcodes. METHODS:The subject h...

journal_title：Pharmacoepidemiology and drug safety

authors： Hwang Y,Yoon D,Ahn EK,Hwang H,Park RW

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:The Centers for Medicare & Medicaid Services claims comprise an administrative database of beneficiary-specific clinical information. This study evaluates the impacts of (i) claim information updates (claims adjudication) and (ii) delay in claim processing (claims delay) on real-time evaluation of health servic...

journal_title：Pharmacoepidemiology and drug safety

authors： Hartzema AG,Racoosin JA,MaCurdy TE,Gibbs JM,Kelman JA

更新日期：2011-07-01 00:00:00