A detection algorithm for drug-induced liver injury in medical information databases using the Japanese diagnostic scale and its comparison with the Council for International Organizations of Medical Sciences/the Roussel Uclaf Causality Assessment Method

abstract：PURPOSE:The objective of this study was to determine the fraction of variance in patient-level medication adherence accounted for by prescribers and pharmacies. METHODS:We used prescription drug claims paid between January 2010 and July 2011 to a national pharmacy benefits manager to define implementation during persi...

journal_title：Pharmacoepidemiology and drug safety

authors： Genberg BL,Rogers WH,Lee Y,Qato DM,Dore DD,Hutchins DS,Brennan T,Matlin OS,Wilson IB

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to examine trends in potentially inappropriate medication (PIM) prescribing in Norwegian nursing homes. METHODS:Patients aged ≥70 years were included from three cross-sectional studies conducted in 1997, 2005 and 2011. PIMs were analyzed according to the Norwegian General Practice-Nur...

journal_title：Pharmacoepidemiology and drug safety

authors： Halvorsen KH,Selbaek G,Ruths S

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:This study aimed to evaluate the risks of upper gastrointestinal (GI) adverse events across a variety of oral and parenteral coxibs and nonselective nonsteroidal anti-inflammatory drugs (nsNSAIDs) in the general population of Taiwan. METHODS:In a case-crossover study, all patients aged ≥20 years who were hospi...

journal_title：Pharmacoepidemiology and drug safety

authors： Chang CH,Chen HC,Lin JW,Kuo CW,Shau WY,Lai MS

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Tramadol is a weak opioid analgesic, which is generally considered to be safe. However, conflicting data exist on the dependence potential of tramadol. OBJECTIVE:The aim of this study was to investigate occurrence of tramadol dependence and associated risk factors using spontaneously reported adverse drug r...

journal_title：Pharmacoepidemiology and drug safety

authors： Tjäderborn M,Jönsson AK,Ahlner J,Hägg S

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:Days supply (prescription duration) values are commonly used to estimate drug exposure and quantify adherence to therapy, yet accuracy is not routinely assessed, and potential inaccurate reporting has been previously identified. We examined the impact of cleaning days supply values on the measurement of adheren...

journal_title：Pharmacoepidemiology and drug safety

authors： Burden AM,Paterson JM,Gruneir A,Cadarette SM

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To assess the reason for the relative high risk of local complications for women following cardiac catheterization by evaluating the associations between gender, sheath size, and local adverse outcomes following cardiac catheterization. METHODS:The data used in this study were obtained from a portion of the Am...

journal_title：Pharmacoepidemiology and drug safety

authors： Tavris DR,Gallauresi BA,Dey S,Brindis R,Mitchel K

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:To determine healthcare claim patterns associated using nonsteroidal anti-inflammatory drugs (NSAIDs) for rheumatoid arthritis (RA). METHODS:The CADEUS study randomly identified NSAID users within the French health insurance database. One-year claims data were extracted, and NSAID indication was obtained from ...

journal_title：Pharmacoepidemiology and drug safety

authors： Bernard MA,Bénichou J,Blin P,Weill A,Bégaud B,Abouelfath A,Moore N,Fourrier-Réglat A,CADEUS Team.

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:Although sales of prescribed and over-the-counter (OTC) medication are rising, little is known about individual drug intake. This study was aimed to obtain complementary information about drug intake. METHOD:Information on drug utilization was obtained in a female cohort for five different time points (TP): 36...

journal_title：Pharmacoepidemiology and drug safety

authors： Hoeke H,Roeder S,Bertsche T,Borte M,von Bergen M,Wissenbach DK

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:We developed an adverse events (AEs) reporting form for Korean folk medicine. METHODS:The first version of the form was developed and tested in the clinical setting for spontaneous reporting of AEs. Additional revisions to the reporting form were made based on collected data and expert input. RESULTS:We devel...

journal_title：Pharmacoepidemiology and drug safety

authors： Park JH,Choi SM,Moon S,Kim S,Kim B,Kim MK,Lee S

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:To develop and validate an algorithm to identify preterm infants in the absence of birth certificates within Medicaid data. METHODS:Medicaid fee-for-service claims data from Florida (FL) and Texas (TX) were linked to vital statistics data for infants who were continuously eligible during the first 3 months fol...

journal_title：Pharmacoepidemiology and drug safety

authors： Eworuke E,Hampp C,Saidi A,Winterstein AG

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:The use of prescription opioid analgesics has been increasing over the last few decades in Australia. In particular, oxycodone and fentanyl have increased substantially. We examined the gender and age trends in the prescribing of subsidised opioid analgesics in the Australian population for non-palliative care ...

journal_title：Pharmacoepidemiology and drug safety

authors： Hollingworth SA,Gray PD,Hall WD,Najman JM

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:To investigate a possible increased risk of esophageal obstruction among users of loratadine and pseudoephedrine (Claritin-D 24-Hour [C-D 24], the original, round, extended-release formulation) compared to two other tablet formulations of loratadine. METHODS:Pharmacy data of 12 managed care plans were screened...

journal_title：Pharmacoepidemiology and drug safety

authors： Manda B,Drinkard CR,Shatin D,Graham DJ

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Non-adherence is considered a major barrier to better outcomes of diabetes care. A relationship has been established between polypharmacy and patients' adherence. This study aims to investigate the occurrence of polypharmacy and non-adherence in general practice, their mutual relationship and the as...

journal_title：Pharmacoepidemiology and drug safety

authors： van Bruggen R,Gorter K,Stolk RP,Zuithoff P,Klungel OH,Rutten GE

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:This paper introduces an improved tool for designing matched-pairs randomized trials. The tool allows the incorporation of clinical and other knowledge regarding the relative importance of variables used in matching and allows for multiple types of missing data. The method is illustrated in the context of a clu...

journal_title：Pharmacoepidemiology and drug safety

authors： Greevy RA Jr,Grijalva CG,Roumie CL,Beck C,Hung AM,Murff HJ,Liu X,Griffin MR

更新日期：2012-05-01 00:00:00

abstract：:The use of healthcare databases in research provides advantages such as increased speed, lower costs and limitation of some biases. However, database research has its own challenges as studies must be performed within the limitations of resources, which often are the product of complex healthcare systems. The primary ...

journal_title：Pharmacoepidemiology and drug safety

authors： Hall GC,Sauer B,Bourke A,Brown JS,Reynolds MW,LoCasale R

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:The abuse and nonmedical use of prescription opioids and its subsequent consequences are an important public health concern. This phenomenon has paralleled the increase in the therapeutic use of opioids for pain management. There is thus a need to measure prescription opioid abuse to understand trends over time...

journal_title：Pharmacoepidemiology and drug safety

authors： Secora AM,Dormitzer CM,Staffa JA,Dal Pan GJ

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:Because health insurance claims lack clinical information, comparative effectiveness research studies that rely on these data may be challenging to interpret and may result in biased inference. We conducted an exploratory study to determine if medical information contained in patient charts could offer clinical...

journal_title：Pharmacoepidemiology and drug safety

authors： Croghan TW,Esposito D,Daniel G,Wahl P,Stoto MA

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:The aim of this study was to estimate the prevalence of first-generation antipsychotics (FGA) prescribed for treatment of psychiatric and neurological conditions and use of benztropine to reduce extrapyramidal side effects (EPS) by patient race/ethnicity in a nationally representative sample of adult outpatient...

journal_title：Pharmacoepidemiology and drug safety

authors： Cook TB,Reeves GM,Teufel J,Postolache TT

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:Direct oral anticoagulants (DOACs) have been promoted in patients with nonvalvular atrial fibrillation (nv-AF) as a more convenient alternative to vitamin K antagonists. We estimated 1-year dabigatran and rivaroxaban adherence rates in nv-AF patients and assessed associations between baseline patient characteri...

journal_title：Pharmacoepidemiology and drug safety

authors： Maura G,Pariente A,Alla F,Billionnet C

更新日期：2017-11-01 00:00:00

abstract：:The cost of drugs represents 10% of the National Health Service (NHS) budget in the UK and this fraction is increasing. Because the NHS is centrally funded and because there is a budgetary limit, prioritization in health care is required. The National Institute for Clinical Excellence in England and Wales and the Heal...

journal_title：Pharmacoepidemiology and drug safety

authors： Beard K

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:Increased post-marketing reports of 'interstitial pneumonia' as an adverse drug reaction (ADR) from the use of gefitinib, irinotecan, or leflunomide among patients in Japan have not been noted in other countries. The WHO International Drug Monitoring Database was analyzed to examine Japan's pattern of reporting...

journal_title：Pharmacoepidemiology and drug safety

authors： Koo LC,Clark JA,Quesenberry CP,Higenbottam T,Nyberg F,Wolf MK,Steinberg MH,Forsythe BH

更新日期：2005-11-01 00:00:00

abstract：PURPOSE:We review statistical methods for assessing the possible impact of bias due to unmeasured confounding in real world data analysis and provide detailed recommendations for choosing among the methods. METHODS:By updating an earlier systematic review, we summarize modern statistical best practices for evaluating ...

journal_title：Pharmacoepidemiology and drug safety

authors： Zhang X,Stamey JD,Mathur MB

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:To compare birth outcomes between women exposed and unexposed to the antiviral medications oseltamivir or zanamivir during pregnancy. METHODS:This was an observational cohort study including women who gave birth to singletons in Sweden 2005-2007 and their infants. We obtained information from the national heal...

journal_title：Pharmacoepidemiology and drug safety

authors： Svensson T,Granath F,Stephansson O,Kieler H

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:Although a series of serious adverse events have continually raised concerns about the potential toxicity of traditional Chinese medicine injections (TCM injections), studies on this subject are still sparse. We conducted a descriptive analysis of a spontaneous reporting system in China to describe the safety p...

journal_title：Pharmacoepidemiology and drug safety

authors： Li H,Deng J,Deng L,Ren X,Xia J

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Deferasirox (DFX) is an effective and well-tolerated oral iron chelator elevating the adherence to iron chelating therapy among patients with iron overload. However, the US Food and Drug Administration issued a warning about the potential adverse events associated with DFX in 2010. METHODS:To examine the ri...

journal_title：Pharmacoepidemiology and drug safety

authors： Huang WF,Chou HC,Tsai YW,Hsiao FY

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To study patterns of antiepileptic drugs (AED) prescribing, particularly valproate, during pregnancy over a 10-year period in the UK, Italy, and France. METHODS:Data on pregnancies conceived after 1 January 2007 with outcomes before 31 December 2016 were extracted from four European electronic health care data...

journal_title：Pharmacoepidemiology and drug safety

authors： Hurault-Delarue C,Morris JK,Charlton R,Gini R,Loane M,Pierini A,Puccini A,Neville A,Snowball J,Damase-Michel C,EUROmediSAFE consortium.

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To study the human teratogenic potential of two acetylsalicylic acid (ASA) drugs ASA-100 mg and ASA-500 mg. DESIGN:Pair analysis of cases with congenital abnormalities and matched healthy controls. SETTINGS:The large population-based dataset of the Hungarian Case-Control Surveillance of Congenital Abnormali...

journal_title：Pharmacoepidemiology and drug safety

authors： Czeizel AE,Rockenbauer M,Mosonyi A

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:To evaluate the frequency, severity and preventability of warfarin-induced cerebral haemorrhages due to warfarin and warfarin-drug interactions in patients living in the county of Ostergötland, Sweden. METHODS:All patients with a diagnosed cerebral haemorrhage at three hospitals during the period 2000-2002 wer...

journal_title：Pharmacoepidemiology and drug safety

authors： Jönsson AK,Spigset O,Jacobsson I,Hägg S

更新日期：2007-03-01 00:00:00

abstract：PURPOSES:(1) Measure the prevalence of herbal product (HP) use, alone, and concomitantly with prescribed medications during pregnancy, (2) identify the most frequently consumed HP during gestation and (3) determine predictors of HP use at the beginning of pregnancy, and during the third trimester. METHODS:A questionna...

journal_title：Pharmacoepidemiology and drug safety

authors： Moussally K,Oraichi D,Bérard A

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:This study was performed to evaluate the change of prescribing patterns after the regulatory action regarding fluoroquinolones in pediatric patients. METHODS:We conducted a time series analysis using the Korea Health Insurance Review and Assessment Service National Patients Sample database. Study subjects cons...

journal_title：Pharmacoepidemiology and drug safety

authors： Shin JY,Kim MH,Shin SM,Lee SH,Park BJ

更新日期：2014-12-01 00:00:00