Abstract:
:Tc-99m hexamethylpropylene amineoxime (HMPAO) is a novel radiopharmaceutical demonstrated to be a sensitive indicator of abnormalities of cerebral perfusion. Most reports in the literature have evaluated patients with gross perfusion deficits, such as cerebrovascular accidents, and with dementia, where patterns of diffuse perfusion deficit were reported comparable with those seen in PET studies. We report a patient in whom there was the rapid onset of dementia, with the HMPAO images demonstrating diffuse loss of cortical perfusion in a nonfocal, and nonsegmental, fashion. Correlation with postmortem examination demonstrates good concordance between the diffuse nature of HMPAO loss, and diffuse cortical necrosis throughout both cerebral hemispheres. The technique was shown to be more sensitive than transmission CT scanning in demonstrating the extent of the deficit, and it correlated closely with the functional deficits noted in the patient.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
McEwan AJ,Jackson FI,Catz Z,Schmidt RP,Hooper HR,Mattjews JJdoi
10.1097/00003072-199103000-00007subject
Has Abstractpub_date
1991-03-01 00:00:00pages
167-9issue
3eissn
0363-9762issn
1536-0229journal_volume
16pub_type
杂志文章abstract::Kimura disease is a chronic inflammatory disorder that occurs mainly in Asians. We present a patient with pulmonary Kimura disease assessed by whole-body 18F-FDG PET/CT examination and proved by pathologic findings. Chest x-ray detected left pulmonary hilum enlargement in a 49-year-old Chinese man. CT showed a soft ti...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182867d70
更新日期:2013-07-01 00:00:00
abstract::There are occasional reports of a hiatal hernia demonstrating thoracic uptake on I-131 scintigraphy. This is a cause of a potential false-positive appearance mimicking a pulmonary or mediastinal metastasis. Hiatal hernia is 1 of a number of causes of false-positive I-131 whole-body scans. Although previous case report...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.RLU.0000079663.56340.18
更新日期:2003-08-01 00:00:00
abstract::Unexplained false-positive accumulation of In-111 leukocyte in the gastrointestinal tract has been reported previously. In a pediatric population, uptake in the submandibular gland was noted in 19 of 42 children. This is believed to be a normal finding in children that is not seen in adults. In some of these 19 childr...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198711000-00010
更新日期:1987-11-01 00:00:00
abstract:PURPOSE:The purpose of this study was to describe our department's experience with the fused imaging-guided radiotherapy (FIGURA) system for planning radiation treatment of high-risk neuroblastoma. PATIENTS AND METHODS:Between 1999 and 2002, 11 patients received radiation therapy as consolidation after chemotherapy in...
journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/01.rlu.0000214481.43868.bf
更新日期:2006-05-01 00:00:00
abstract::In this study, we report the results of using fluorine deoxyglucose positron emission tomography/computed tomography (FDG PET/CT) to guide the antifungal therapy against chronic disseminated candidiasis in patients with acute leukemia. Three adult patients were enrolled in this study. All patients underwent a series o...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181e4db84
更新日期:2010-08-01 00:00:00
abstract::The goal of bleeding scintigraphy is to localize the site of origin of a hemorrhage to within general regions of the large or small bowel. Activity is typically seen to extravasate from the blood pool into the lumen, and the collection of activity then moves on sequential images, as a result of the cathartic action of...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200201000-00006
更新日期:2002-01-01 00:00:00
abstract::An automated volume determination program using SPECT imaging with Tc-99m has been validated by both phantom and patient studies. Its use for monitoring change of function of the liver and change in tumor mass during different therapy regimes has been assessed. The technique is not restricted to the estimation of the ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199007000-00009
更新日期:1990-07-01 00:00:00
abstract::In 14 patients with ophthalmoplegia plus Tc-99m hexamethylpropylene amineoxime (HMPAO) brain SPECT imaging was performed. Three patients showed bilateral parieto-occipital hypoperfusions, and two patients had left parietal defects (one with an additional right temporal lesion). Two patients presented with occipital hy...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199101000-00005
更新日期:1991-01-01 00:00:00
abstract::A 57-year-old man with a history of metastatic melanoma and sclerotic bone lesions seen on CT was referred for F NaF PET/CT evaluation of active skeletal metastases. While the bone lesions had no uptake and were therefore thought to represent sequela of previously treated disease, an unexpected area of F NaF uptake wa...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000371
更新日期:2014-10-01 00:00:00
abstract::A 43-year-old woman who had a history of right mastectomy for breast cancer presented with fever and swelling in the right supraclavicular region during her second course of chemotherapy. An FDG PET/CT was performed to evaluate this patient, which revealed mildly increased FDG activity in the lymph node in the supracl...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181b06c2f
更新日期:2009-09-01 00:00:00
abstract::A 48-year-old woman presented with abdominal pain, and her initial investigations, which included an abdominal ultrasound and a pelvic MRI examination, revealed a dominant soft tissue mass abutting her left iliac bone, extensive pelvic adenopathy, and multiple osseous metastases. The findings were concerning for chond...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000674
更新日期:2015-03-01 00:00:00
abstract::Recently, myocardial blood flow quantitation with dynamic SPECT has been validated to enhance the detection of multivessel coronary artery disease (CAD) and conclude equivocal SPECT myocardial perfusion study. This advance opened an important clinical application to utilize the tool in guiding CAD management for area ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001726
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:The need for a low-iodine diet (LID) to maximize the results of radioactive iodine uptake (RAIU), nuclear medicine thyroid scintigraphy, and ultimately treatment of thyroid cancer patients is widely accepted. Failure to follow the prescribed diet can alter RAIU results, thyroid scan findings, and poststudy mana...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181662f9e
更新日期:2008-04-01 00:00:00
abstract::Erlotinib is a reversible epidermal growth factor receptor tyrosine kinase inhibitor used to treat advanced non-small cell lung carcinoma patients who have shown progression on at least 1 prior chemotherapy regimen. Most of the patients on erlotinib show cutaneous adverse effects. We report the 18F-FDG PET/CT findings...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000586
更新日期:2015-04-01 00:00:00
abstract::Perfusion lung scintigraphy using SPECT/CT is one mainstay in diagnosing pulmonary embolism. Although typically almost all tracer will be accumulated in the lung capillaries, occasionally abnormal uptake can be detected. As superior vena cava syndrome leads to aberrant blood flow, tracer injected to an arm vein might ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003127
更新日期:2020-10-01 00:00:00
abstract::I-131 metaiodobenzylguanidine (MIBG) imaging was performed in 38 patients with advanced neuroblastoma. Abnormal images were found in patients with elevations of urinary vanillylmandelic acid and dopamine and high serum neuron-specific enolase levels. Normal or minimal elevation of markers was seen in patients with neg...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198801000-00014
更新日期:1988-01-01 00:00:00
abstract::Gallium-67 distribution in normal patients is well known; it is also known that the concentration in some tissues may vary according to an individual physiologic stimulus. In this report, the case of a young woman is presented who was studied 15 days after a cesarean section and showed physiologic and pathologic Ga-67...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198402000-00011
更新日期:1984-02-01 00:00:00
abstract::Radionuclide angiography (RNA) and cholescintigraphy were performed prospectively in 300 patients with suspected acute cholecystitis (AC). Of 79 patients with positive RNA, 63 had AC (80%). Positive RNA was seen in 23 of 26 cases with gangrenous AC (88%) while 12 of the 26 had a positive "rim" sign (46%). All 12 patie...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198912000-00001
更新日期:1989-12-01 00:00:00
abstract::Infections that are associated with health care are a major problem that results in many deaths, suffering, and a great deal of extra monetary costs. Fortunately, there is much that can be done to prevent these infections. This article is a brief introduction to prevention of some of the common hospital acquired infec...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,评审
doi:10.1097/RLU.0000000000001309
更新日期:2016-10-01 00:00:00
abstract::Spinal metastases are rare in head and neck cancer. We present a rare case of vocal cord squamous cell cancer that metastasized to the spinal cord and cauda equina. A 63-year-old man presented with acute back pain and bilateral leg weakness 5 months after having a surgical treatment for moderately differentiated vocal...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001825
更新日期:2017-11-01 00:00:00
abstract::Two cases with Ga-PSMA-avid prostate cancer recurrence in the vas deferens are presented. These cases highlight the clinical importance of imaging the pattern of local prostate cancer recurrence and the potential difficulties that arise due to the altered anatomy in the prostate bed after prostatectomy or radiotherapy...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002837
更新日期:2020-01-01 00:00:00
abstract::The cardiac apical mass of Hodgkin's disease, an infrequent presentation of lymphomas, can be selectively labeled with 67Ga-citrate. Three cases are presented illustrating the value of 67Ga scintigraphy in the differential diagnosis of pericardial masses, as well as its role in the management and assessment of therapy...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197802000-00002
更新日期:1978-02-01 00:00:00
abstract::A 31-year-old woman underwent Tc-labeled UBI scanning for diagnosis of possible prosthesis infection evaluation in our department. The scan showed an area of increased tracer uptake in the mid-lateral portion of the left thigh. This was proven to be due to a retained surgical gauze in her left thigh. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001389
更新日期:2016-12-01 00:00:00
abstract::Ten years after chemoradiation for primary lymphoma of the left pelvic bone, a 38-year-old man presented with a 4-month history of gradually increasing pain in his left upper leg and thigh. Initial radiographs and contrast-enhanced magnetic resonance imaging were consistent with recurrent lymphoma, infection, or posti...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318217561c
更新日期:2011-07-01 00:00:00
abstract::Squamous cell carcinoma is the most common malignant neoplasm of the oral cavity, and it contributes approximately 90% of all oral malignancies. We present a case of a squamous cell carcinoma of the tongue with rare site of bilateral adrenal metastases on F-FDG PET/CT with response evaluation after chemotherapy. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001521
更新日期:2017-02-01 00:00:00
abstract::The evaluation of a painful hip prosthesis for suspected loosening frequently requires a multi-modality approach. Radionuclide arthroscintigraphy is a valuable adjunct to contrast arthrography, demonstrating greater sensitivity than contrast arthrography in detecting loosening of the femoral component of the prosthesi...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199111000-00004
更新日期:1991-11-01 00:00:00
abstract:PURPOSE:The authors' goal was to determine whether the prevalence of pulmonary embolism in patients with matching ventilation-perfusion (V-Q) defects and chest radiographic opacities differs depending on the degree of perfusion deficit (absent versus decreased). METHODS:The authors performed a retrospective analysis o...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200009000-00002
更新日期:2000-09-01 00:00:00
abstract::A 73-year-old man with chronic obstructive pulmonary disease and no known malignancies was evaluated for back pain. MR examination showed lumbar spine compression fractures, and an F-FDG PET/CT scan was requested to assess for skeletal metastatic disease and potential detection of a primary neoplasm. The PET/CT examin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003154
更新日期:2020-08-01 00:00:00
abstract::We report a 58-year-old man whose incidentally discovered papillary thyroid carcinoma in the left lobe showed high FDG and low FLT uptake on PET/CT. The SUVmax was 19.7 for FDG and 3.0 for FLT. The Ki-67 labeling index of the tumor was 1.9%. Thus, the low FLT uptake might be attributed to the low proliferative activit...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318252d80f
更新日期:2012-06-01 00:00:00
abstract::Liver imaging was performed in two patients with traumatic right hemidiaphragmatic hernia. It has elucidated the cause of obliteration of the right hemidiaphragmatic shadow on the chest x-ray. These cases are illustrative of the usefulness of liver imaging in the diagnosis of traumatic right hemidiaphragmatic hernia a...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198501000-00008
更新日期:1985-01-01 00:00:00