Abstract:
PURPOSE:The purpose of this study was to describe our department's experience with the fused imaging-guided radiotherapy (FIGURA) system for planning radiation treatment of high-risk neuroblastoma. PATIENTS AND METHODS:Between 1999 and 2002, 11 patients received radiation therapy as consolidation after chemotherapy in 9 and for palliation in 2. Diagnostic metaiodobenzylguanidine (MIBG) imaging was used, which is specific for neuroblastoma, to identify the residual tumor, followed by computed tomography scanning in the radiation treatment position. The FIGURA software fused the images obtained by the 2 modalities and transferred the result to a 3-dimensional radiation treatment planning system. Radiation was delivered at a total dose of 25.2 Gy according to the FIGURA. RESULTS:Five patients achieved complete remission and 2 partial remission; 3 were stabilized. One child with a highly rapid progressive course died of the disease. CONCLUSION:FIGURA is a new, feasible technique for defining target volumes. By using standard hospital equipment, it is possible to treat residual disease identified by sensitive metaiodobenzylguanidine imaging and localized with the anatomic computed tomography scan. Treating a more accurate target volume spares normal tissue and organs and minimizes side effects.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Fenig E,Mishaeli M,Yerushalmi R,Sever ZB,Ash S,Kornreich L,Yaniv I,Steinmetz Adoi
10.1097/01.rlu.0000214481.43868.bfsubject
Has Abstractpub_date
2006-05-01 00:00:00pages
256-8issue
5eissn
0363-9762issn
1536-0229pii
00003072-200605000-00002journal_volume
31pub_type
临床试验,杂志文章abstract::Olivopontocerebellar atrophy is a rare neurodegenerative syndrome associated with 2 distinct disorders: multiple system atrophy and spinocerebellar ataxia. We present a case involving a 66-year-old man with adult-onset progressing cerebellar signs reflective of a cerebellar syndrome with no significant family history ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003180
更新日期:2020-09-01 00:00:00
abstract::A 47-year-old woman with a history of surgically treated abdominal paraganglioma and left thigh melanoma underwent an F-FDOPA PET/CT for suspected locoregional recurrence of paraganglioma. F-FDOPA PET/CT disconfirmed this recurrence but revealed 2 FDOPA-avid left inguinal lymph nodes, confirmed on a subsequent F-FDG P...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003233
更新日期:2020-10-01 00:00:00
abstract::Quantitative perfusion scans were used to predict the proportion of pulmonary function lost by inclusion of lung in radiotherapy fields. Nineteen patients receiving radiotherapy for carcinoma of the lung had pulmonary function evaluated by forced expiratory volume at 1 second (FEV1) prior to and following radiotherapy...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198809000-00006
更新日期:1988-09-01 00:00:00
abstract::We detail the history and evaluation of a 68-year-old man who had head-to-toe PET/CT scanning that showed a focal area of increased FDG uptake in the left medial foot. This was thought to be recurrence of his melanoma. The patient was asymptomatic. He had a history of malignant melanoma of the right ear, which was rem...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181662b69
更新日期:2008-04-01 00:00:00
abstract::A patient receiving nephrotoxic chemotherapy for metastatic cervical cancer was examined for acute renal failure. A Tc-99m MAG3 scan showed symmetric function, bilateral increasing parenchymal activity, and no tracer excretion in either collecting system. The differential diagnosis included cisplatin-induced nephrotox...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200202000-00007
更新日期:2002-02-01 00:00:00
abstract::Technetium-99m red blood cell (RBC) scintigraphy is a very specific method to differentiate a hemangioma from other hepatic masses. The authors report a case of hepatocellular carcinoma that showed a focal area of increased uptake on Tc-99m RBC SPECT in a 60-year-old man. Dynamic computed tomography and angiography re...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200101000-00008
更新日期:2001-01-01 00:00:00
abstract::The omentum is a rare metastatic site for prostatic adenocarcinoma. We present a case of metastatic castrate-resistant prostate cancer, with progressive omentum invasive prostate cancer identified on prostate-specific membrane antigen (PSMA) PET/CT scan. Omental biopsy revealed metastatic prostate adenocarcinoma, and ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001619
更新日期:2017-06-01 00:00:00
abstract::Incidental findings on PET CT studies are common. The distribution of Ga-DOTATATE is dependent on cell surface expression of somatostatin receptors, which may be pathologic or physiologic. Osteoporosis circumscripta is the early lytic phase of Paget disease associated with well-defined osteopenia, most commonly seen w...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002567
更新日期:2019-06-01 00:00:00
abstract::Hepatobiliary scintigraphy has been recognized as a useful diagnostic tool in detecting the presence and site of bile leaks. The authors report a case of bile ascites secondary to a postsurgical biliary leak, the scintigraphic findings in bile ascites, and the potential use of paracentesis, in combination with hepatob...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198506000-00004
更新日期:1985-06-01 00:00:00
abstract::Abnormal accumulation of Tc-99m MDP in two metastatic lesions of the liver was observed in a patient with resected colon carcinoma. Single-photon emission computed tomography (SPECT) revealed characteristic marginal accumulation of Tc-99m MDP in both of those metastatic lesions. X-ray CT showed the corresponding margi...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198501000-00004
更新日期:1985-01-01 00:00:00
abstract:ABSTRACT:A 13-year-old boy with mediastinal T-cell lymphoblastic lymphoma demonstrated an altered biodistribution with diffuse activity in subcutaneous white adipose tissue and decreased visceral activity on interim posttreatment FDG PET/CT. This altered biodistribution was attributed to administration of the chemother...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003340
更新日期:2021-03-01 00:00:00
abstract::Acute suppurative thyroiditis is an uncommon condition. Most patients have preexisting oropharyngeal fistulae. Penetrating oropharyngeal injuries resulting from swallowed foreign bodies provide an acquired channel of infection spreading into the relatively resistant thyroid gland. The authors describe a patient with i...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200004000-00001
更新日期:2000-04-01 00:00:00
abstract::A 58-year-old man was referred for selective internal radiation therapy for locally advanced unresectable hepatocellular carcinoma. Intra-arterial particle perfusion scintigraphy was performed with SPECT/CT following intra-arterial injection of Tc macroaggregated albumin. Angiography demonstrated a hepatic falciform a...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001907
更新日期:2018-01-01 00:00:00
abstract::Tc-99m sestamibi imaging was performed in two patients with multiple myeloma. Focal areas of increased uptake in one patient and diffuse skeletal uptake in the second patient were found. Tc-99m sestamibi appears to identify bone marrow and osteolytic involvement in multiple myeloma. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199902000-00009
更新日期:1999-02-01 00:00:00
abstract:INTRODUCTION:The purpose of presurgical assessment is to delimit the epileptogenic zone and the functional deficit zone with a brain MRI, an electroencephalograph or even a stereo-electroencephalograph (SEEG), neuropsychological evaluation, and a cerebral FDG PET. Several studies concur that the hypometabolism of FDG P...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002615
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:To investigate whether the evaluation of tumors, lymphoid cell-rich organs, and immune-related adverse events (IRAE) with F-FDG PET/CT can predict the efficacy and outcome of immunotherapy. METHODS:Forty patients who underwent F-FDG-PET/CT scans before and after therapy with immune checkpoint inhibitors from D...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002453
更新日期:2019-04-01 00:00:00
abstract::A 43-year-old woman confined to bed and wheelchair due to multiple sclerosis (MS) presented with complaints of sharp, bilateral hip pain (left greater than right) that radiated to the thighs with point tenderness to trochanteric palpation. She had received several courses of high-dose intravenous corticosteroids for M...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::A 66-year-old woman had fever, rash, and joint pain. Physical examination revealed multiple enlarged lymph nodes. A possibility of lymphoma was considered and FDG PET/CT was performed, which demonstrated elevated FDG activity not only in many lymph nodes but also in the spleen and liver. However, adult-onset Still dis...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31826386d2
更新日期:2012-10-01 00:00:00
abstract::The Transcatheter Valve Therapy Registry has been very helpful in providing data to better understand patient risk factors for transcatheter aortic valve replacement (TAVR). The outcome of TAVR depends on many patient indicators, some of which are given in this article, including the age, dependence on oxygen, classif...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001806
更新日期:2018-01-01 00:00:00
abstract::In a patient with AIDS, marked uptake of Ga-67 in the stomach walls initially was regarded with a high degree of suspicion for gastric involvement. Results of subsequent intragastric tests, including biopsy and culture, proved negative. Caution should be exercised when considering further costly and/or invasive proced...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198602000-00015
更新日期:1986-02-01 00:00:00
abstract::There have been numerous initiatives to improve quality and safety in surgery. Goal-directed fluid therapy and a quality bundle for emergency laparotomy surgery are two of them. The establishment of a Universal Protocol to prevent the wrong procedure, the wrong patient having a procedure, or the wrong site for a proce...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001472
更新日期:2017-03-01 00:00:00
abstract::Metastatic calcifications according to histopathologic and scintigraphic findings have been well-defined. The authors report a postoperative case of hyperparathyroidism with multiple metastatic calcifications in the lung, kidney, stomach, heart, and vessels that were primarily detected by bone scintigraphy and demonst...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199202000-00010
更新日期:1992-02-01 00:00:00
abstract::Findings on cholescintigraphy in gallbladder carcinoma are described in five patients. Four patients presenting with acute cholecystitis had nonvisualization of the gallbladder with normal hepatoenteric transit time. One of these had a large portal mass and two had liver metastasis as additional findings. The fifth pa...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198604000-00013
更新日期:1986-04-01 00:00:00
abstract::Here we describe a 77-year-old man with a solitary fibrous tumor of the pleura showing increasing tracer uptake at Ga-DOTATOC PET/CT, demonstrating that solitary fibrous tumor of the pleura may overexpress somatostatin receptors, therefore mimicking neuroendocrine tumors at somatostatin receptor PET/CT. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001648
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the efficacy of ¹⁸F-choline PET/CT (18FCH-PET/CT) in restaging patients previously treated by radical prostatectomy for a prostate cancer, presenting with biochemical relapse during follow-up (FU). PATIENTS AND METHODS:Three hundred thirty-one patients referred to us from ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318266cc38
更新日期:2013-01-01 00:00:00
abstract::We describe the results of F-FDG PET/CT of 3 patients referred to our institution during the single day of Monday, March 23, 2020, for an initial assessment of cancer extension or for the therapeutic evaluation of chemotherapy of neoplastic pathology, with no obvious infectious or respiratory symptoms at the time of e...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003255
更新日期:2020-12-01 00:00:00
abstract::Computed tomography is the standard diagnostic examination employed to identify the morbid anatomy of cerebrospinal fluid spaces in children. This noninvasive technique provides excellent anatomic information. However, CT only indirectly characterizes the cerebral spinal fluid pathways. When it is necessary to determi...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197910000-00006
更新日期:1979-10-01 00:00:00
abstract::Chordoma is a rare slow-growing neoplasm of neuroectodermal origin, which frequently recurs after removal and has the potential to metastasize. We present the case of a 53-year-old man with metastasizing chordoma who underwent F-FDG and Ga-DOTA-TATE PET/CT for restaging of disease and for evaluation of targeted radion...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001576
更新日期:2017-04-01 00:00:00
abstract:AIM:to evaluate the treatment response in patients with recurrent colorectal cancer (CRC) using FDG PET/CT. MATERIALS AND METHODS:a total of 32 recurrent CRC patients (21 males, 11 females; mean age, 52.8 years) were included in this retrospective study. All patients underwent a baseline and follow-up FDG PET/CT scans...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181feeb48
更新日期:2011-01-01 00:00:00
abstract::An unusual phenomenon during lung scintigraphy is presented. Besides visualization of the lungs, accumulation of Tc-99m macroaggregated albumin (MAA) was seen in a small part of the liver and in and around several thoracic vertebrae. Contrast-enhanced radiographic computed tomography revealed extensive collateral path...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200412000-00004
更新日期:2004-12-01 00:00:00