Low-iodine diet revisited: importance in nuclear medicine imaging and management.

Abstract:

PURPOSE:The need for a low-iodine diet (LID) to maximize the results of radioactive iodine uptake (RAIU), nuclear medicine thyroid scintigraphy, and ultimately treatment of thyroid cancer patients is widely accepted. Failure to follow the prescribed diet can alter RAIU results, thyroid scan findings, and poststudy management. OBJECTIVE:Provided is a case presentation that illustrates the need for adequate patient understanding and compliance with the LID. METHODS:We present the clinical history, laboratory values, and pertinent imaging of a 21-year-old woman with papillary thyroid cancer. The patient's post-thyroidectomy I-123 and 2 subsequent thyroid (I-123 and post-RAI ablation I-131) scintigraphy examinations are reviewed as well as the patient's urine iodine levels. RESULTS:In this case of a woman with papillary thyroid cancer, the nuclear medicine whole body and neck pinhole images revealed that compliance to an LID positively impacts the overall management. After an LID was followed, the patient's urine iodine level appropriately declined from the previously elevated level. Initial negative results on thyroid scintigraphy caused by noncompliance with the LID became positive when the patient adhered to the prescribed dietary regimen. CONCLUSION:An LID is an integral element in the management of differentiated thyroid cancer. Proper guidance and emphasis on the implementation of the diet needs to be provided to patients. Noncompliance may lead to false negative imaging results, misleading the medical professionals and patient. Potentially inadequate management of the patient's thyroid cancer may follow.

journal_name

Clin Nucl Med

authors

Hinds SR 2nd,Stack AL,Stocker DJ

doi

10.1097/RLU.0b013e3181662f9e

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

247-50

issue

4

eissn

0363-9762

issn

1536-0229

pii

00003072-200804000-00001

journal_volume

33

pub_type

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