Usefulness of PET/CT for detecting a second primary cancer after treatment for squamous cell carcinoma of the head and neck.

Abstract:

PURPOSE:Patients with squamous cell carcinoma of the head and neck have been reported to have a high rate of second primary cancer of the upper aerodigestive tract. This study was performed to determine whether positron emission tomography/computed tomography (PET/CT) is useful for detecting a second primary cancer after treatment for squamous cell carcinoma of the head and neck. METHODS AND MATERIALS:The PET/CT findings in 279 consecutive patients (211 men, 68 women; mean age 62 years) who had been treated for squamous cell carcinomas of the head and neck were examined and compared with the findings obtained by other imaging modalities, the biopsy results, and the clinical data. RESULTS:Thirty second primary cancers were documented in 28 of the 279 subjects. Based on PET/CT findings, the overall risk of a second primary cancer in 1 year was 9.9% and the risk in the upper aerodigestive tract region was 6.8% (19/279). CONCLUSIONS:PET/CT enabled early detection of a second cancer in patients treated for head and neck cancer.

journal_name

Clin Nucl Med

authors

Bold B,Piao Y,Murata Y,Kishino M,Shibuya H

doi

10.1097/RLU.0b013e31818bf27d

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

831-3

issue

12

eissn

0363-9762

issn

1536-0229

pii

00003072-200812000-00001

journal_volume

33

pub_type

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