A rare case of ectopic adrenocorticotropic hormone syndrome caused by a metastatic neuroendocrine tumor of the pancreas detected by 68Ga-DOTANOC and 18F-FDG PET/CT.

Abstract:

:We report a rare case of ectopic adrenocorticotropic hormone (ACTH) syndrome caused by a metastatic neuroendocrine tumor (NET) of the pancreas detected by PET/CT using different tracers. A 43-year-old female patient with Cushing syndrome (CS) by suspected ectopic ACTH secretion underwent a 68Ga-DOTANOC and a 18F-FDG PET/CT. Both these functional imaging techniques revealed increased tracer uptake in a pancreatic mass and multiple liver metastases. Histology showed the presence of a mildly differentiated pancreatic NET. 68Ga-DOTANOC PET/CT may be a useful functional imaging method, complementary to 18F-FDG PET/CT, in detecting ACTH-secreting pancreatic NETs.

journal_name

Clin Nucl Med

authors

Treglia G,Salomone E,Petrone G,Giaccari A,Rindi G,Rufini V

doi

10.1097/RLU.0b013e318279ec68

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

e306-8

issue

7

eissn

0363-9762

issn

1536-0229

journal_volume

38

pub_type

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