Electrically evoked auditory brainstem response: refractory properties and strength-duration functions.

Abstract:

:The electrically evoked auditory brainstem potential (EABR) was recorded in users of both the Nucleus cochlear implant and the Ineraid cochlear implant. The refractory properties of the EABR were evaluated by measuring the response amplitude to a two-pulse stimulus where the interpulse interval was varied. The threshold of response for a single pulse stimulus was also measured as a function of the duration of the biphasic pulse. These strength-duration functions were then used to calculate an EABR chronaxie measure. Both of these measures showed a similar range for the monopolar stimulation used with the Ineraid implant and the bipolar stimulation used with the Nucleus implant. Neither of these two measures of the temporal response properties showed any clear relationship to the ability of individual subjects to perform on a speech perception task.

journal_name

Hear Res

journal_title

Hearing research

authors

Abbas PJ,Brown CJ

doi

10.1016/0378-5955(91)90012-x

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

139-47

issue

1

eissn

0378-5955

issn

1878-5891

pii

0378-5955(91)90012-X

journal_volume

51

pub_type

杂志文章
  • An active process in cochlear mechanics.

    abstract::A model for cochlear mechanics is proposed to take account of its two systems, one passive and one active. The classical passive system stimulates the inner hair cells directly at levels above about 40 dB SL. At intensities below about 60 dB an active process, the 'cochlear amplifier' (CA), somehow provides additional...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(83)90136-3

    authors: Davis H

    更新日期:1983-01-01 00:00:00

  • Corticofugal Modulation of DPOAEs in Gerbils.

    abstract::Efferent auditory feedback on cochlear hair cells is well studied regarding olivocochlear brainstem mechanisms. Less is known about how the descending corticofugal system may shape efferent feedback and modulate cochlear mechanics. Distortion-product otoacoustic emissions (DPOAEs) are a suitable tool to assess outer h...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2015.11.008

    authors: Jäger K,Kössl M

    更新日期:2016-02-01 00:00:00

  • Intracellular Ca2+ buffers can dramatically affect Ca2+ conductances in hair cells.

    abstract::The effects of endogenous and exogenous Ca(2+) buffers on Ca(2+) current kinetics have been investigated by patch clamp in hair cells mechanically isolated from frog semicircular canals. This preparation displays at least three different Ca(2+) channel types: transient currents flow through a drug-resistant channel ("...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2004.05.009

    authors: Martini M,Rispoli G,Farinelli F,Fesce R,Rossi ML

    更新日期:2004-09-01 00:00:00

  • Contributions of von Békésy to psychoacoustics.

    abstract::This paper reviews the contributions of von Békésy to psychoacoustics, comparing his findings and interpretations to those that have emerged since his work. The areas covered include the perception of pitch for pure tones and complex tones, the effect of frequency on the apparent location of pure tones, estimation of ...

    journal_title:Hearing research

    pub_type: 历史文章,杂志文章,评审

    doi:10.1016/j.heares.2012.04.009

    authors: Moore BC

    更新日期:2012-11-01 00:00:00

  • Hyperpolarization-activated current (Ih) in primary auditory neurons.

    abstract::A hyperpolarization-activated current (termed I[h]) is believed to provide a pacemaker depolarization in sinoatrial node cells and in some central and peripheral neurons. In the present study, we examined if such an inward cation current exists in primary auditory neurons using the whole-cell patch-clamp technique. A ...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(97)00078-6

    authors: Chen C

    更新日期:1997-08-01 00:00:00

  • Minimal sex differences in gene expression in the rat superior olivary complex.

    abstract::A critical issue in large-scale gene expression analysis is the impact of sexually dimorphic genes, which may confound the results when sampling across sexes. Here, we assessed, for the first time, sex differences at the transcriptome level in the auditory brainstem. To this end, microarray experiments covering the wh...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2008.08.008

    authors: Ehmann H,Salzig C,Lang P,Friauf E,Nothwang HG

    更新日期:2008-11-01 00:00:00

  • The isolated in vitro perfused spiral modiolar artery: pressure dependence of vasoconstriction.

    abstract::We developed a new technique, the isolated in vitro perfused spiral modiolar artery, which allowed the continuous measurement of the vascular diameter and control of the intravascular pressure. An isolated section of the spiral modiolar artery from the gerbil was perfused on one end with a set of concentric pipettes a...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(97)00184-6

    authors: Wangemann P,Gruber DD

    更新日期:1998-01-01 00:00:00

  • Glycine induced calcium concentration changes in vestibular type I sensory cells.

    abstract::Glutamate is the neurotransmitter of the synapse between vestibular type I hair cells and the afferent nerve calyx. This calyx may also be involved in local feedback, which may modify sensory cell activity via N-methyl-D-aspartate (NMDA) receptors. Glycine is the co-agonist of glutamate in NMDA receptor activation. Bo...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(99)00194-x

    authors: Devau G

    更新日期:2000-02-01 00:00:00

  • Functional localization of auditory cortical fields of human: click-train stimulation.

    abstract::Averaged auditory evoked potentials (AEPs) to bilaterally presented 100 Hz click trains were recorded from multiple sites simultaneously within Heschl's gyrus (HG) and on the posterolateral surface of the superior temporal gyrus (STG) in epilepsy-surgery patients. Three auditory fields were identified based on AEP wav...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2007.11.012

    authors: Brugge JF,Volkov IO,Oya H,Kawasaki H,Reale RA,Fenoy A,Steinschneider M,Howard MA 3rd

    更新日期:2008-04-01 00:00:00

  • Stimulus frequency otoacoustic emissions in the Northern leopard frog, Rana pipiens pipiens: implications for inner ear mechanics.

    abstract::Otoacoustic emissions (OAEs) are weak sounds that originate from the inner ear which are traditionally classified/named based on their evoking stimulus. Recently, it has been argued that such a classification, at least for mammals, misrepresents the underlying mechanisms of emission-generation. As an alternative class...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2006.07.009

    authors: Meenderink SW,Narins PM

    更新日期:2006-10-01 00:00:00

  • Cortical encoding of pitch: recent results and open questions.

    abstract::It is widely appreciated that the key predictor of the pitch of a sound is its periodicity. Neural structures which support pitch perception must therefore be able to reflect the repetition rate of a sound, but this alone is not sufficient. Since pitch is a psychoacoustic property, a putative cortical code for pitch m...

    journal_title:Hearing research

    pub_type: 杂志文章,评审

    doi:10.1016/j.heares.2010.04.015

    authors: Walker KM,Bizley JK,King AJ,Schnupp JW

    更新日期:2011-01-01 00:00:00

  • Potassium-induced release of an endogenous toxic activity for outer hair cells and auditory neurons in the cochlea: a new pathophysiological mechanism in Menière's disease?

    abstract::In Menière's disease, the increase of extracellular potassium concentration in the perilymph is thought to play a key role in determining the progressive loss of cochlear hair cells. In this paper, we describe a serum-free culture preparation of hair cells from 5 day-old rat and report the release by the cochlea, in r...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(90)90168-o

    authors: Lefebvre PP,Weber T,Rigo JM,Delree P,Leprince P,Moonen G

    更新日期:1990-08-01 00:00:00

  • Ultrastructure and immunohistochemical identification of the extracellular matrix of the chinchilla cochlea.

    abstract::The molecular composition and three-dimensional organization of the extracellular matrix (ECM) was studied by immunofluorescent microscopy, transmission and scanning electron microscopy in three connective tissue structures of the cochlea: the spiral limbus, basilar membrane and spiral ligament. Type II collagen, fibr...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(98)00219-6

    authors: Tsuprun V,Santi P

    更新日期:1999-03-01 00:00:00

  • Reactions of human auditory cortex to a change in tone duration.

    abstract::Auditory evoked magnetic fields were measured using a stimulation sequence where repetitive identical tone bursts were randomly and infrequently replaced by shorter tones. The deviation in the stimulus duration evoked a specific response, the mismatch field, peaking about 130 ms after the end of the shorter stimulus. ...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(89)90174-3

    authors: Kaukoranta E,Sams M,Hari R,Hämäläinen M,Näätänen R

    更新日期:1989-08-01 00:00:00

  • Contribution of stapedial artery to blood flow in the cochlea and its surrounding bone.

    abstract::This study was performed to elucidate the contribution of the stapedial artery (SA)--which has been considered to be independent of the vertebrobasilar system--to blood flow in the ear by observing ear blood flow in Sprague-Dawley rats. A laser-Doppler (LD) probe was positioned on the bony wall of the cochlear basal t...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(03)00310-1

    authors: Yamamoto H,Tominaga M,Sone M,Nakashima T

    更新日期:2003-12-01 00:00:00

  • Effects of stimulus level on electrode-place discrimination in human subjects with cochlear implants.

    abstract::Effects of stimulus level on discrimination of one stimulation site from another were examined in 15 human subjects with Nucleus-22 cochlear implant systems. Bipolar stimulation was used in all cases with electrodes in the bipolar pair separated by 1.5 mm (center to center). Subjects were first tested at a medium loud...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(99)00079-9

    authors: Pfingst BE,Holloway LA,Zwolan TA,Collins LM

    更新日期:1999-08-01 00:00:00

  • Physiology of cochlear efferent and afferent neurons: direct comparisons in the same animal.

    abstract::Exposure of the vestibulo-cochlear anastomosis in the cat allows single-unit recording of afferent fibers originating from inner hair cells and olivocochlear efferent fibers to the outer hair cells. Comparison of data obtained from individual animals show similarities in absolute threshold and dynamic range between th...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(88)90105-0

    authors: Liberman MC

    更新日期:1988-07-15 00:00:00

  • A mechanism of adaptation to hypergravity in the statocyst of Aplysia californica.

    abstract::The gravity-sensing organ of Aplysia californica consists of bilaterally paired statocysts containing statoconia, which are granules composed of calcium carbonate crystals in an organic matrix. In early embryonic development, Aplysia contain a single granule called a statolith, and as the animal matures, statoconia pr...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(96)00147-5

    authors: Pedrozo HA,Schwartz Z,Luther M,Dean DD,Boyan BD,Wiederhold ML

    更新日期:1996-12-01 00:00:00

  • Experiments in comparative hearing: Georg von Békésy and beyond.

    abstract::Georg von Békésy was one of the first comparative auditory researchers. He not only studied basilar membrane (BM) movements in a range of mammals of widely different sizes, he also worked on the chicken basilar papilla and the frog middle ear. We show that, in mammals, at least, his data do not differ from those that ...

    journal_title:Hearing research

    pub_type: 历史文章,杂志文章,评审

    doi:10.1016/j.heares.2012.04.013

    authors: Manley GA,Narins PM,Fay RR

    更新日期:2012-11-01 00:00:00

  • Electromotile hearing: evidence from basilar membrane motion and otoacoustic emissions.

    abstract::Electrical stimulation of the cochlea is known to cause auditory sensations in humans and other animals. It also has been shown to produce emissions of sound from the inner ear. In the current study we investigate the relationship between electrically induced motion of the basilar membrane (BM) and the production of o...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(95)00216-2

    authors: Nuttall AL,Ren T

    更新日期:1995-12-01 00:00:00

  • Tone-induced stereocilia lesions as a function of exposure level and duration in the hamster cochlea.

    abstract::The present study presents an atlas of the effects of 10 kHz tone exposures of different levels and durations on cochlear hair cells and their stereocilia in the Syrian golden hamster. Animals were sound exposed while under anesthesia. The exposure conditions were varied over an intensity range of 90-129 dB SPL; at th...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(92)90022-f

    authors: Kaltenbach JA,Schmidt RN,Kaplan CR

    更新日期:1992-07-01 00:00:00

  • Outer hair cell electromotility: the sensitivity and vulnerability of the DC component.

    abstract::A technique was devised in order to study the fast electromechanical length changes of outer hair cells at low stimulus levels. Solitary outer hair cells were drawn into a glass microchamber. Length changes were evoked by the application of transcellular potentials and were detected with a photodiode. The method is no...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(91)90019-6

    authors: Evans BN,Hallworth R,Dallos P

    更新日期:1991-04-01 00:00:00

  • Disparities in auditory physiology and pathology between C57BL/6J and C57BL/6N substrains.

    abstract::C57BL/6 inbred mice are frequently used as models in auditory research, mostly the C57BL/6J and C57BL/6N substrains. Genetic variation and phenotypic disparities between these two substrains have been extensively investigated, but conflicting information exists about differences in their auditory and vestibular phenot...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2014.10.005

    authors: Kendall A,Schacht J

    更新日期:2014-12-01 00:00:00

  • Fish inner ear otolith size and bilateral asymmetry during development.

    abstract::Size and bilateral asymmetry (i.e. size difference between the left and the right hand side) of inner ear otoliths of larval mouthbreeding cichlid fish were determined during the ontogenetic development of larvae from hatching to the free swimming stage. Animals of two batches were raised in aquarium hatch baskets. Th...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(98)00067-7

    authors: Anken RH,Werner K,Ibsch M,Rahmann H

    更新日期:1998-07-01 00:00:00

  • Nitrosoglutathione suppresses cochlear potentials and DPOAEs but not outer hair cell currents or voltage-dependent capacitance.

    abstract::Biochemical and pharmacological evidence support a role for nitric oxide (NO) and glutathione (GSH) in the cochlea. GSH combines with NO in tissue to form nitrosoglutathione (GSNO) that can act as a storage form for GSH and NO. Therefore, we tested GSNO on sound-evoked responses of the cochlea (cochlear microphonic, C...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(97)00065-8

    authors: Nenov AP,Skellett RA,Fallon M,Bobbin RP

    更新日期:1997-08-01 00:00:00

  • Effect of inter-phase gap on the sensitivity of cochlear implant users to electrical stimulation.

    abstract::Human behavioral thresholds for trains of biphasic pulses applied to a single channel of Nucleus CI24 and LAURA cochlear implants were measured as a function of inter-phase gap (IPG). Experiment 1 used bipolar stimulation, a 100-pps pulse rate, and a 400-ms stimulus duration. In one condition, the two phases of each p...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2005.03.021

    authors: Carlyon RP,van Wieringen A,Deeks JM,Long CJ,Lyzenga J,Wouters J

    更新日期:2005-07-01 00:00:00

  • The order of testing effect in otoacoustic emissions and its consequences for sex and ear differences in neonates.

    abstract::The amplitude values of transient-evoked otoacoustic emissions, recorded from a large sample of neonates, were used to examine the asymmetry between ears tested and the differences due to the sex of the subject. Whilst the sex difference, with females having larger responses than males, has been a consistent finding i...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(03)00234-x

    authors: Thornton AR,Marotta N,Kennedy CR

    更新日期:2003-10-01 00:00:00

  • The influence of inner hair cell loss on the instantaneous frequency of the cochlear microphonic.

    abstract::The cochlear microphonic (CM) is produced by a change in standing currents during the motion of the cochlear partition. The motion of the partition and associated hair cell transduction processes are nonlinear and are reflected in the variation of the instantaneous frequency (IF) of the CM. Although the CM is dominate...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(02)00642-1

    authors: Chertoff ME,Amani-Taleshi D,Guo Y,Burkard R

    更新日期:2002-12-01 00:00:00

  • Spatial hearing ability of the pigmented Guinea pig (Cavia porcellus): Minimum audible angle and spatial release from masking in azimuth.

    abstract::Despite the common use of guinea pigs in investigations of the neural mechanisms of binaural and spatial hearing, their behavioral capabilities in spatial hearing tasks have surprisingly not been thoroughly investigated. To begin to fill this void, we tested the spatial hearing of adult male guinea pigs in several exp...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2018.04.011

    authors: Greene NT,Anbuhl KL,Ferber AT,DeGuzman M,Allen PD,Tollin DJ

    更新日期:2018-08-01 00:00:00

  • Neurotrophin and neurotrophin receptor mRNA expression in developing inner ear.

    abstract::Receptors which bind the neurotrophins NGF, BDNF, NT-3 and NT-4/5 were shown to be present in cochlear and vestibular ganglion cells during development, implying a neurotrophic role for these molecules in the inner ear. We have found by in situ hybridization that cochlear and vestibular sensory epithelial cells expres...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(94)90286-0

    authors: Schecterson LC,Bothwell M

    更新日期:1994-02-01 00:00:00