Biometry of the cornea and anterior chamber in chinese eyes: an anterior segment optical coherence tomography study.

Abstract:

:PURPOSE. To investigate the normative data of corneal and anterior segment biometric parameters and their associations in Chinese adults, for use in preoperative assessment for corneal and anterior segment surgery. METHODS. This cross-sectional, population-based study included 750 subjects aged > or =50 years. The subjects underwent an ophthalmic examination including imaging with anterior segment optical coherence tomography (AS-OCT). Dimensions were subsequently measured with the Zhongshan Assessment Program (ZAP). Also measured was posterior corneal arc length (PCAL), a novel parameter defined as the arc distance between scleral spurs on the posterior border of the cornea. Correlations with age, sex, height, weight, body mass index (BMI), refractive sphere and cylinder, and intraocular pressure were also measured. RESULTS. The subjects' mean age was 63.3 +/- 7.9 years and 349 (46.5%) were men. Corneal parameters (mean +/- SD) included PCAL (12.924 +/- 0.544 mm), anterior chamber depth (ACD; 2.684 +/- 0.309 mm), central corneal thickness (562.39 +/- 31.85 microm), anterior chamber curvature (7.35 +/- 0.37 mm), and posterior corneal curvature (6.65 +/- 0.34 mm). A moderate correlation was observed between PCAL and ACD (R = 0.55, P < 0.001) and a poor correlation between PCAL and age, height, weight, and BMI. Multivariate analysis showed a significant association between PCAL and ACD, ACC, PCC, and cylinder (P < 0.05). CONCLUSIONS. In this Chinese population, PCAL was found to correlate moderately with ACD. The data may be useful for corneal and anterior segment procedures such as Descemet's stripping automated endothelial keratoplasty (DSAEK).

authors

Yuen LH,He M,Aung T,Htoon HM,Tan DT,Mehta JS

doi

10.1167/iovs.09-4307

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

3433-40

issue

7

eissn

0146-0404

issn

1552-5783

pii

iovs.09-4307

journal_volume

51

pub_type

杂志文章
  • Quantitative measurements of autofluorescence with the scanning laser ophthalmoscope.

    abstract:PURPOSE:To evaluate the feasibility and reliability of a standardized approach for quantitative measurements of fundus autofluorescence (AF) in images obtained with a confocal scanning laser ophthalmoscope (cSLO). METHODS:AF images (30°) were acquired in 34 normal subjects (age range, 20-55 years) with two different c...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.11-8319

    authors: Delori F,Greenberg JP,Woods RL,Fischer J,Duncker T,Sparrow J,Smith RT

    更新日期:2011-12-09 00:00:00

  • Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells.

    abstract:PURPOSE:To identify matrix metalloproteinases (MMPs) released by ciliary smooth muscle cells in vitro and to determine whether MMP release is altered by exposure to prostaglandins (PGs). METHODS:Human ciliary smooth muscle cells were grown to confluence in monolayer cultures and treated with PGF2 alpha, 11-deoxy-PGE1,...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Weinreb RN,Kashiwagi K,Kashiwagi F,Tsukahara S,Lindsey JD

    更新日期:1997-12-01 00:00:00

  • Attenuated glial reaction in experimental proliferative vitreoretinopathy treated with liposomal doxorubicin.

    abstract:PURPOSE:We investigated the therapeutic effect of liposomal doxorubicin (Lipo-dox) on experimental proliferative vitreoretinopathy (PVR). METHODS:The toxicity of Lipo-dox was determined in vitro in cultured rabbit retinal pigment epithelium (RPE) cells by tetrazolium-based (MTT) assay for cell viability performed 48 a...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.11-7972

    authors: Kuo HK,Chen YH,Wu PC,Wu YC,Huang F,Kuo CW,Lo LH,Shiea J

    更新日期:2012-06-29 00:00:00

  • Violation of the ISNT rule in Nonglaucomatous pediatric optic disc cupping.

    abstract:PURPOSE:To determine whether nonglaucomatous optic disc cupping in children violates the ISNT rule (which states that for normal optic discs the neuroretinal rim width is greatest in the order inferior >or= superior >or= nasal >or= temporal). METHODS:Digital ocular fundus photographs from a random cohort of children w...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.09-3837

    authors: Pogrebniak AE,Wehrung B,Pogrebniak KL,Shetty RK,Crawford P

    更新日期:2010-02-01 00:00:00

  • The importance of Bcl-xL in the survival of human RPE cells.

    abstract:PURPOSE:In normal eyes and in diseases such as age-related macular degeneration (AMD) and proliferative vitreoretinopathy (PVR), retinal pigment epithelial (RPE) cell survival is critically important. Bcl-x(L) has been shown to be among the most highly expressed survival factors in cultured human RPE cells. In the curr...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.06-1145

    authors: Zhang N,Peairs JJ,Yang P,Tyrrell J,Roberts J,Kole R,Jaffe GJ

    更新日期:2007-08-01 00:00:00

  • The role of Src family kinases in cortical cataract formation.

    abstract:PURPOSE:The goal of this study was to determine the role of Src family kinases (SFKs) in the development of lens cataract. This question was particularly significant, because these tyrosine kinases mediate the stress pathways known to lead to cataract formation. The experiments were focused on whether the inhibition of...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Zhou J,Menko AS

    更新日期:2002-07-01 00:00:00

  • AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization.

    abstract:PURPOSE:Adeno-associated viral (AAV) vectors have been used to express several different proteins in the eye. The purpose of this study was to determine whether AAV-mediated intraocular gene transfer of pigment epithelium-derived factor (PEDF) inhibits the development of choroidal neovascularization (CNV) in a murine m...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Mori K,Gehlbach P,Yamamoto S,Duh E,Zack DJ,Li Q,Berns KI,Raisler BJ,Hauswirth WW,Campochiaro PA

    更新日期:2002-06-01 00:00:00

  • The effects of protein kinase C on trabecular meshwork and ciliary muscle contractility.

    abstract:PURPOSE:The possible role of protein kinase C (PKC) inhibitors in novel pressure-lowering drugs is currently under investigation. To gain further insight into regulation of contractility by PKC in trabecular meshwork (TM) and ciliary muscle (CM), the effects of various PKC inhibitors and activators were tested. METHOD...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Thieme H,Nass JU,Nuskovski M,Bechrakis NE,Stumpff F,Strauss O,Wiederholt M

    更新日期:1999-12-01 00:00:00

  • Objective concurrent measures of open-loop accommodation and vergence under photopic conditions.

    abstract:PURPOSE:To investigate the relationship between photopic open-loop accommodation and vergence and the effect of mental effort on these positions. METHODS:Twenty subjects (11 men and 9 women) viewed monocularly a photopic (25 cdm-2), high-contrast (90%) Maltese cross-target for 3 minutes, through a 0.5-mm pinhole drill...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Gray LS,Winn B,Gilmartin B,Eadie AS

    更新日期:1993-09-01 00:00:00

  • Genomic organization of the human TIMP-1 gene. Investigation of a causative role in the pathogenesis of X-linked retinitis pigmentosa 2.

    abstract:PURPOSE:To evaluate the role of TIMP-1 in inherited retinal degeneration. METHODS:The genomic structure of the TIMP-1 gene was established and male patients with x-linked retinitis pigmentosa 2 from five families were screened for sequence alterations by direct sequencing in all exons, exon-intron boundaries, and the ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Hardcastle AJ,Thiselton DL,Nayudu M,Hampson RM,Bhattacharya SS

    更新日期:1997-08-01 00:00:00

  • Choroidal blood flow regulation after posture change or isometric exercise in men with obstructive sleep apnea syndrome.

    abstract:PURPOSE:Obstructive sleep apnea (OSA) syndrome generates hypertension, atherosclerosis, and endothelial and autonomic dysfunction, which may mutually interact with ocular vascular regulation. Exercise and posture changes can be used to manipulate blood pressure, ocular perfusion pressure (OPP), or both. It was hypothes...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章,随机对照试验

    doi:10.1167/iovs.11-7936

    authors: Khayi H,Pepin JL,Geiser MH,Tonini M,Tamisier R,Renard E,Baguet JP,Levy P,Romanet JP,Chiquet C

    更新日期:2011-12-16 00:00:00

  • A murine model for retinopathy of prematurity identifies endothelial cell proliferation as a potential mechanism for plus disease.

    abstract:PURPOSE:To characterize the features and possible mechanism of plus disease in the mouse oxygen-induced retinopathy (OIR) model for retinopathy of prematurity. METHODS:Wild-type and Adam (A Disintegrin And Metalloproteinase) knockout mice were exposed to 75% oxygen from postnatal day 7 to 12 (P7 to P12) (hyperoxia), t...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.12-11492

    authors: Guaiquil VH,Hewing NJ,Chiang MF,Rosenblatt MI,Chan RV,Blobel CP

    更新日期:2013-08-07 00:00:00

  • Visual fields of infants assessed with a new perimetric technique.

    abstract::The visual field of normal infants was assessed using a perimeter with LED stimuli and a forced-choice observation procedure. Central fixation was elicited by four central, pulsing LEDs and maintained with the aid of auditory stimuli. Field extent was derived from the four-alternative, forced-choice judgments of an ad...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Mayer DL,Fulton AB,Cummings MF

    更新日期:1988-03-01 00:00:00

  • Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye.

    abstract:Purpose:Tumor necrosis factor (TNF)-α is upregulated in eyes following corneal alkali injury and contributes to corneal and also retinal damage. Prompt TNF-α inhibition by systemic infliximab ameliorates retinal damage and improves corneal wound healing. However, systemic administration of TNF-α inhibitors carries risk...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.16-20339

    authors: Zhou C,Robert MC,Kapoulea V,Lei F,Stagner AM,Jakobiec FA,Dohlman CH,Paschalis EI

    更新日期:2017-01-01 00:00:00

  • Recording three-dimensional eye movements: scleral search coils versus video oculography.

    abstract:PURPOSE:This study compared the performance of a video-based infrared three-dimensional eye tracker device (Chronos) with the scleral search coil method. METHODS:Three-dimensional eye movements were measured simultaneously with both systems during fixation, saccades, optokinetic stimulation, and vestibular stimulation...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.05-0234

    authors: Houben MM,Goumans J,van der Steen J

    更新日期:2006-01-01 00:00:00

  • Cell proliferation and interleukin-6-type cytokine signaling are implicated by gene expression responses in early optic nerve head injury in rat glaucoma.

    abstract:PURPOSE:In glaucoma, the optic nerve head (ONH) is the principal site of initial axonal injury, and elevated intraocular pressure (IOP) is the predominant risk factor. However, the initial responses of the ONH to elevated IOP are unknown. Here the authors use a rat glaucoma model to characterize ONH gene expression cha...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.10-5317

    authors: Johnson EC,Doser TA,Cepurna WO,Dyck JA,Jia L,Guo Y,Lambert WS,Morrison JC

    更新日期:2011-01-25 00:00:00

  • Dibutyryl cyclic adenosine monophosphate and forskolin alter the paracellular pathway in cultured corneal endothelial cells.

    abstract:PURPOSE:This study describes the effects of the cyclic adenosine monophosphate (cAMP) pathway on the tight junctional barrier of the corneal endothelium, which plays a critical role in maintaining the corneal stroma in an underhydrated, transparent state. METHODS:Subcultured bovine corneal endothelial cells grown on f...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Le Varlet B,Ducroc R,Dagonet FB,Pouliquen Y,Vandewalle A,Hirsch M

    更新日期:1995-11-01 00:00:00

  • Elevated expression of transglutaminase 1 and keratinization-related proteins in conjunctiva in severe ocular surface disease.

    abstract:PURPOSE:In severe ocular surface diseases, pathologic keratinization of the ordinarily nonkeratinized corneal and conjunctival mucosal epithelia results in severe visual loss. The expression in conjunctivalized corneas of various proteins known to play important roles in the physiological keratinization process in huma...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Nakamura T,Nishida K,Dota A,Matsuki M,Yamanishi K,Kinoshita S

    更新日期:2001-03-01 00:00:00

  • Accommodative facility in eyes with and without myopia.

    abstract:PURPOSE:To compare accommodative facility in eyes with myopia to that in eyes with emmetropia or hyperopia and to determine whether accommodative facility can be used to predict an association with myopia. METHODS:In the Sydney Myopia Study, year-1 school children (6.7 +/- 0.4 years) were assessed for accommodative fa...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章,多中心研究

    doi:10.1167/iovs.05-1078

    authors: Pandian A,Sankaridurg PR,Naduvilath T,O'Leary D,Sweeney DF,Rose K,Mitchell P

    更新日期:2006-11-01 00:00:00

  • Latent stereopsis for motion in depth in strabismic amblyopia.

    abstract:PURPOSE:To investigate the residual stereo function of a group of 15 patients with strabismic amblyopia, by using motion-in-depth stimuli that allow discrimination of contributions from local disparity as opposed to those from local velocity mechanisms as a function of the rate of depth change. METHODS:The stereo perf...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.09-3551

    authors: Hess RF,Mansouri B,Thompson B,Gheorghiu E

    更新日期:2009-10-01 00:00:00

  • Impact of reticular pseudodrusen on microperimetry and multifocal electroretinography in intermediate age-related macular degeneration.

    abstract:PURPOSE:To examine the influence of reticular pseudodrusen (RPD) on retinal and visual function in intermediate AMD using multifocal electroretinography (mfERG) and microperimetry. METHODS:In a prospective cross-sectional study, microperimetry and mfERG testing, followed by color fundus photography, near-infrared refl...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.14-16210

    authors: Wu Z,Ayton LN,Makeyeva G,Guymer RH,Luu CD

    更新日期:2015-03-03 00:00:00

  • Platelet activating factor inhibits fluid transport by corneal endothelium.

    abstract:PURPOSE:Given reports of corneal edema after endothelial exposure to platelet activating factor (PAF), the authors have investigated whether PAF can affect the function of corneal endothelium in vitro. METHODS:The endothelial side of deepithelialized rabbit corneas was perfused with BSS+ and test agents: PAF, its inac...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Zhu Z,Kuang K,Kang F,Li J,Fischbarg J

    更新日期:1996-08-01 00:00:00

  • Effect of image quality, color, and format on the measurement of retinal vascular fractal dimension.

    abstract:PURPOSE:Fractal dimension of retinal vasculature is a global summary measure of retinal vascular network pattern and geometry. This study was conducted to examine the effect of variations in image color, brightness, focus, contrast, and format on the measurement of retinal vascular fractal dimension. METHODS:A set of ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.09-4129

    authors: Wainwright A,Liew G,Burlutsky G,Rochtchina E,Zhang YP,Hsu W,Lee JM,Wong TY,Mitchell P,Wang JJ

    更新日期:2010-11-01 00:00:00

  • Evaluating macular function using the focal ERG.

    abstract::A stimulus consisting of 96 red LEDs mounted in the rear of a ganzfeld bowl was used to elicit focal electroretinograms (FERG) from the central 9 degrees of the retina in human subjects. The luminance of the stimulus was driven sinusoidally at frequencies from 10-60 Hz. The temporal responsiveness and response phase l...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Seiple WH,Siegel IM,Carr RE,Mayron C

    更新日期:1986-07-01 00:00:00

  • Impairments of contrast discrimination and contrast adaptation in glaucoma.

    abstract:PURPOSE:Contrast detection is commonly measured clinically; however, discrimination between contrasts is also important for natural vision. Furthermore, optimal performance requires the visual system to adapt to ambient contrast conditions. Recent studies of primate neurophysiology demonstrate significant retinal invol...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.08-3332

    authors: McKendrick AM,Sampson GP,Walland MJ,Badcock DR

    更新日期:2010-02-01 00:00:00

  • Extended slow phase in latent/manifest latent nystagmus.

    abstract:PURPOSE:To investigate the slow phase in latent/manifest latent nystagmus (LMLN) by producing long eye-drift intervals devoid of fast phases (extended slow phases [ESPs]) and to relate ESP metrics to clinical findings. METHODS:Ten patients with LMLN had eye movements recorded while attending to paired visual and audit...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.03-0324

    authors: Gradstein L,Goldstein HP,Wizov SS,Reinecke RD

    更新日期:2004-04-01 00:00:00

  • Selective Early Glial Reactivity in the Visual Pathway Precedes Axonal Loss, Following Short-Term Cerebrospinal Fluid Pressure Reduction.

    abstract:Purpose:To examine the early glial reactivity and neuron damage in response to short-term cerebrospinal fluid pressure (CSFp) reduction, as compared with intraocular pressure (IOP) elevation. Methods:The experiment included 54 male Sprague-Dawley rats with elevated translaminar cribrosa pressure difference (TLPD), def...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.17-22232

    authors: Li XX,Zhang Z,Zeng HY,Wu S,Liu L,Zhang JX,Liu Q,Yang DY,Wang NL

    更新日期:2018-07-02 00:00:00

  • Reduction of apoptosis in ischemic retinas of two mouse models using hyperbaric oxygen treatment.

    abstract:PURPOSE:To investigate the effect of hyperbaric oxygen (HBO) chamber treatment in mouse models of retinal ischemia. METHODS:Unilateral central retinal artery occlusion (CRAO) or optic nerve crush (ONC) was induced in 50 mice each, of which 30 were treated with 100% oxygen at 2 atm for 90 minutes immediately after inju...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.11-7574

    authors: Gaydar V,Ezrachi D,Dratviman-Storobinsky O,Hofstetter S,Avraham-Lubin BC,Goldenberg-Cohen N

    更新日期:2011-09-29 00:00:00

  • A CX3CR1 genotype associated with retinal vasculitis in patients in the United Kingdom.

    abstract:PURPOSE:To investigate whether polymorphisms in the gene encoding the chemokine receptor CX3CR1, which has been linked to changes in functional ligand-binding activity, are associated with retinal vasculitis (RV) in a cohort of patients in the United Kingdom. METHODS:DNA was prepared from whole blood of 126 patients w...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.05-1631

    authors: Wallace GR,Vaughan RW,Kondeatis E,Mathew R,Chen Y,Graham EM,Stanford MR

    更新日期:2006-07-01 00:00:00

  • Peripheral endothelial dysfunction in normal pressure glaucoma.

    abstract:PURPOSE:To assess vascular endothelial function in patients with normal pressure glaucoma using forearm blood flow responses to intra-arterial infusions of endothelial-dependent and -independent vasoactive agents. METHODS:Eight patients with newly diagnosed and untreated normal pressure glaucoma and eight healthy age-...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Henry E,Newby DE,Webb DJ,O'Brien C

    更新日期:1999-07-01 00:00:00