Treatment of platinum-resistant recurrent ovarian cancer using a "predictive molecule targeted routine chemotherapy" system.

abstract：BACKGROUND:Surgical resection is generally considered the main curative treatment for intrahepatic biliary cystadenocarcinoma (IBCA) or suspected IBCAs, but controversy exists regarding the prognosis for IBCAs. This study aimed to describe the clinicopathological characteristics of IBCA and identify prognostic factors ...

journal_title：Chinese medical journal

authors： Xu MY,Shi XJ,Wan T,Liang YR,Wang HG,Zhang WZ,He L,Chen MY,Lyu SC,Zhang WW,Li HX

更新日期：2015-05-05 00:00:00

abstract：OBJECTIVE:To investigate the short- and long-term clinician and angiographic outcome of stenting or angioplasty for chronic total coronary artery occlusion. METHODS:A total of 95 patients with successful percutaneous transluminal coronary angioplasty (PTCA) for total occlusion coronary artery were identified out of 35...

journal_title：Chinese medical journal

authors： Dong S,Jeong M,Cho J,Kang J

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Vascular endothelial dysfunction is considered a key pathophysiologic process for the development of acute lung injury. In this study, we aimed at investigating the effects of unfractionated heparin (UFH) on the lipopolysaccharide (LPS)-induced changes of vascular endothelial-cadherin (VE-cadherin) and the p...

journal_title：Chinese medical journal

authors： Mu ST,Tang J,Ma JQ,Zhong Y,Liu HZ,Ma XC,Zheng Z

更新日期：2020-08-05 00:00:00

abstract：BACKGROUND:Mitochondrial diseases are a group of energy metabolic disorders with multisystem involvements. Variable clinical features present a major challenge in pediatric diagnoses. We summarized the clinical spectrum of m.3243A>G mutation in Chinese pediatric patients, to define the common clinical manifestations an...

journal_title：Chinese medical journal

authors： Xia CY,Liu Y,Liu H,Zhang YC,Ma YN,Qi Y

更新日期：2016-08-20 00:00:00

abstract：BACKGROUND:Pulsed radiofrequency (PRF) application to the dorsal root ganglia can reduce neuropathic pain (NP) in animal models, but the effect of PRF on damaged peripheral nerves has not been examined. We investigated the effect of PRF to the rat sciatic nerve (SN) on pain-related behavior and SN ultrastructure follow...

journal_title：Chinese medical journal

authors： Li DY,Meng L,Ji N,Luo F

更新日期：2015-02-20 00:00:00

abstract：BACKGROUND:Preoperative incisional local anaesthesia with ropivacaine is a common method of providing post-laparoscopy pain relief. The pulmonary recruitment manoeuvre also provides pain relief, but the combined effect of these two methods on pain following laparoscopic procedures has not been reported. We investigated...

journal_title：Chinese medical journal

authors： Liu H,Ma C,Zhang X,Yu C,Yang Y,Song X,Tang Y,Guo X

更新日期：2014-01-01 00:00:00

abstract：Background:The increasing frequency of explosive injuries has increased interest in blast-induced traumatic brain injury (bTBI). Various shock tube models have been used to study bTBI. Mild-to-moderate explosions are often overlooked because of the slow onset or mildness of the symptoms. However, heavy gas cylinders an...

journal_title：Chinese medical journal

authors： Zhou Y,Wen LL,Wang HD,Zhou XM,Fang J,Zhu JH,Ding K

更新日期：2018-10-20 00:00:00

abstract：OBJECTIVE:To explore the effects of thyroid hormone (TH) on cardiac function and peripheral lymphocyte beta-adrenoceptors (beta-ARs) of patients with chronic congestive heart failure (CHF). METHODS:Twenty-eight patients with class III or IV advanced CHF due to dilated cardiomyopathy (DCM) or ischemic cardiomyopathy (I...

journal_title：Chinese medical journal

authors： Lu X,Huang J,Zhang X,Li X,Wang C,Zhang P,Chen Y

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Recent studies have suggested that p38 mitogen-activated protein kinases (MAPK) signalling pathway plays an important role in hepatic fibrosis. This study explored the antifibrotic effect of oxymatrine on tetrachloromethane induced liver fibrosis in rats and its modulation on the p38 MAPK signalling pathway....

journal_title：Chinese medical journal

authors： Deng ZY,Li J,Jin Y,Chen XL,Lü XW

更新日期：2009-06-20 00:00:00

abstract：:Twenty-seven samples of pleomorphic salivary adenoma (PSA) were examined for expression and structure of c-myc, c-Ha-ras, c-erbB-2, c-sis oncogenes by RNA dot blot, DNA dot blot and Southern blot hybridization. Eighteen of 25 PSA showed 5.02 +/- 4.74 fold overexpression of c-myc oncogene, 6 of 19 PSA had 4.91 +/- 3.87...

journal_title：Chinese medical journal

authors： Xue H,Situ ZQ,Wang CJ,Wu JZ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Idiopathic choroidal neovascularization (ICNV) is an uncommon disorder affecting primarily individuals younger than the age of 50 years. In CNV patients, no apparent cause can be determined. This study aimed to evaluate the functional and morphological change of the retina with ICNV in young adults. METHODS...

journal_title：Chinese medical journal

authors： Wang WQ,Liu HY,Lu FQ,Hu WT,Gong YY,Wu Y,Xu S,Wang WJ,Xu X,Wang FH,Sun XD

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Some esophageal cancer patients complicated with depression exhibit cognitive impairments. Frontal electroencephalogram (EEG) may be used as a reliable biomarker for prefrontal-mediated cognitive functions. This study was to investigate alterations of EEG and frontal cognitive impairment in esophageal cancer...

journal_title：Chinese medical journal

authors： Cao Y,Chen X,Xie H,Zou L,Hu LJ,Zhou XJ

更新日期：2017-08-05 00:00:00

abstract：BACKGROUND:Double plate osteosynthesis is the standard treatment for intra-articular fractures of the distal humerus. However, there is still controversy concerning dual plate positions in terms of providing optimal stability. The purpose of this retrospective study was to compare the clinical outcomes in patients with...

journal_title：Chinese medical journal

authors： Lan X,Zhang LH,Tao S,Zhang Q,Liang XD,Yuan BT,Xu WP,Yin P,Tang PF

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:A correct thyroid function reference range is important for the accurate diagnosis of thyroid disease during pregnancy. However, there is no consensus on whether thyroid function reference ranges in Chinese population should follow the America Thyroid Association (ATA) guidelines. This study aimed to establi...

journal_title：Chinese medical journal

authors： Yang X,Meng Y,Zhang Y,Zhang C,Guo F,Yang S,Ding R,Fan JX

更新日期：2019-03-05 00:00:00

abstract：:In 16 dogs the endothelium of the left anterior descending coronary artery was injured mechanically. Then a copper wire was inserted into the lumen as a choke of flow and the vessel was slightly compressed from outside by a constrictor. Eight dogs had been treated beforehand with a preparation of flavone extracted fro...

journal_title：Chinese medical journal

authors： Zhao HY,Fang WY

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVE:To detect the virus in the feces and sera of patients in an outbreak of enterically transmitted non-A, non-E hepatitis, and this review covers the epidemiologic features and experimental infection of this novel virus. DATA SOURCES:Data sources come from our own work on this subject, published and unpublished...

journal_title：Chinese medical journal

authors： Luo K,Zhang L

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) pneumonia is an important issue with significant morbidity and mortality in clinical practice, especially in diabetes mellitus (DM). Studies focusing on S. aureus pneumonia in DM is limited, we sought to make a relatively comprehensive exploration of clinica...

journal_title：Chinese medical journal

authors： Zhang QR,Chen H,Liu B,Zhou M

更新日期：2019-06-20 00:00:00

abstract：BACKGROUND:At present, revascularization is still one of the most critical technologies in orthotopic liver transplantation (OLT). Hepatic artery (HA) variations occur frequently in both donors and recipients. Moreover, there are always some pathological changes in the recipient hepatic artery. If handled improperly, i...

journal_title：Chinese medical journal

authors： Ma Y,Li Q,Ye ZM,Zhu XF,He XS

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Transforming growth factor-beta1 (TGF-beta1) exerts strong fibrogenic potential in culture-activated HSCs. Smad4 is a key intracellular mediator for the transforming growth factor-beta (TGF-beta) superfamily of growth factors. The aim of this study was to assess the effects of the antisense Smad4 gene on Ito...

journal_title：Chinese medical journal

authors： Xu XB,Leng XS,He ZP,Liang ZQ,Lin K,Wei YH,Yu X,Peng JR

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:It has been confirmed that defective expression of human leukocyte antigen class I (HLA-I) molecules can contribute to the immune evasion of cancer cells in some types of cancer. The aim of this study was to examine the expression of HLA class I antigen and the antigen-processing machinery (APM) components i...

journal_title：Chinese medical journal

authors： Ayshamgul H,Ma H,Ilyar S,Zhang LW,Abulizi A

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase (MMP)-2 plays an important role in the remodeling of left ventricles (LVs) and right ventricles (RVs). We investigated the differences of MMP-2 expression between LV and RV in response to nandrolone decanoate (ND), swimming training (ST), and combined ND and ST (NS) in mice, based on...

journal_title：Chinese medical journal

authors： Bai Y,Shi XB,Zhang YQ,Wang YL,Liu XY,Esteve-Pastor MA

更新日期：2018-01-20 00:00:00

abstract：BACKGROUND:Previous studies have suggested that primary degeneration of hair cells causes secondary degeneration of spiral ganglion neurons (SGNs), but the effect of SGN degeneration on hair cells has not been studied. In the adult mouse inner ear ouabain can selectively and permanently induce the degeneration of type ...

journal_title：Chinese medical journal

authors： Yuan Y,Chi F

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The research of cancer in patients on hemodialysis (HD) in China has not been reported. The aim of this study was to investigate the clinical and histological features and outcomes of cancer in Chinese HD patients. METHODS:The study subjects were 49 cancer patients (1.4%) out of 3448 end stage renal disease...

journal_title：Chinese medical journal

authors： Zhou L,Cao YL,Li WG,Fu FT,Zhang L,Wang X,Shi XH

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Bioactive proteins, such as cytokines and chemokines, have not been systematically evaluated in healthy and preeclamptic pregnancies. We aimed to investigate the difference of these proteins between healthy and preeclamptic pregnancies in order to help clarify their potential roles in the pathogenesis of hyp...

journal_title：Chinese medical journal

authors： Wang T,Wang YY,Zhou R,Song CP,Lin W,Niu XY,Zhang L,Hu HZ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Although breast-conserving surgery is one of the standard treatments for breast cancer, few studies have assessed its recent implementation in China. We aimed to clarify the current real-world status of breast-conserving surgery in China. METHODS:This cross-sectional survey relied on data collected by the C...

journal_title：Chinese medical journal

authors： Yu LX,Shi P,Tian XS,Yu ZG,Chinese Society of Breast Surgery.

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:Hippophae rhamnoides L. (HL) exerts antioxidant activities against various oxidative stress conditions. In this study, we investigated effects of extract from HL leaves (HLE) on cell proliferation and neuroblast differentiation in the subgranular zone (SGZ) of the dentate gyrus (DG) of aged gerbils. METHODS...

journal_title：Chinese medical journal

authors： Ahn JH,Chen BH,Park JH,Kim IH,Cho JH,Lee JC,Yan BC,Choi JH,Hwang IK,Park JH,Han SN,Lee YL,Kim MJ,Won MH

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To summarize the recent findings on the epidemiology of medically important, opportunistic invasive fungal infections (IFIs) in China and discuss the relevant social, economical reasons and medical factors. DATA SOURCES:We performed a comprehensive search of both English and Chinese literatures of opportunis...

journal_title：Chinese medical journal

authors： Liao Y,Chen M,Hartmann T,Yang RY,Liao WQ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The columella, nasal tip, lip relationship in the bilateral cleft lip nasal deformity remains a great challenge for plastic surgeon. An esthetically satisfying result is difficult to obtain. A subset of patients with bilateral cleft lip nasal deformity still require columellar lengthening and nasal correctio...

journal_title：Chinese medical journal

authors： Yan W,Zhao ZM,Yin NB,Song T,Li HD,Wu D,Gao F,Wang XG

更新日期：2011-12-01 00:00:00

abstract：:Recombinant DNA Yeast-Derived Hepatitis B Vaccine (RYHB vaccine) is comparable to and can replace Plasma-Derived Hepatitis B Vaccine (PHB vaccine) for the prevention of mother-infant transmission of hepatitis B virus (HBV), but the duration of immune efficacy of RYHB vaccine is not clear. This study indicates the long...

journal_title：Chinese medical journal

authors： Zhu QR,Gu XH,Duan SC,Xu HF

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:To determine the feasibility and accuracy of high-frequency ultrasound in evaluating the left ventricular (LV) structure and function in normal and pressure overload rats and to examine the changes of the left ventricle during its transition from hypertrophy to heart failure. METHODS:Thirty-eight female rats...

journal_title：Chinese medical journal

authors： Xu F,Wang J,Bai X,Yang J,Bai S

更新日期：2002-04-01 00:00:00