Presbyopic spectacle coverage, willingness to pay for near correction, and the impact of correcting uncorrected presbyopia in adults in Zanzibar, East Africa.

Abstract:

PURPOSE:To assess presbyopic spectacle coverage, willingness to pay, and the impact of correcting uncorrected presbyopia in individuals 40 years of age and older in Zanzibar and whether assessment of presbyopia can be incorporated into Rapid Assessment of Blindness (RAAB) surveys. METHODS:A cross-sectional, population-based survey of presbyopia was incorporated into a RAAB survey. The sample size of 400 included individuals older than 50 years (from RAAB survey) and those 40 to 50 years old (from the same household) who had a corrected visual acuity (VA) of at least 6/18 in either eye. An Ophthalmic Clinical Officer (OCO) administered visual function (VF) and quality of life (QOL) questionnaires followed by clinical assessment by an optometrist. Participants requiring a simple near addition were dispensed free readymade spectacles. The same team traced participants 6 months later and readministered the questionnaires. Those requiring new spectacles had their near VA measured and were given spectacles. RESULTS:Three hundred eighty-one participants were examined. The prevalence of presbyopia was 89.2% (340/381) and spectacle coverage was only 17.6%. Barriers to accessing services included spectacles not being a priority and lack of money. At follow-up, 175 (93.6%) of 187 participants given spectacles still had them. Mean satisfaction was high at 89.5%. The mean amount participants were willing to pay for spectacles had increased from 2.17 USD at baseline to 3.14 USD at follow-up. The impact of correcting presbyopia on VF produced an effect size of 2.90 and effect sizes ranging from 1.15 to 3.90 for mean QoL scores. CONCLUSIONS:This study highlights the value of correcting presbyopia from the community perspective and the necessity of providing affordable, quality, and accessible near spectacles at the primary health level.

authors

Laviers HR,Omar F,Jecha H,Kassim G,Gilbert C

doi

10.1167/iovs.08-3154

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

1234-41

issue

2

eissn

0146-0404

issn

1552-5783

pii

iovs.08-3154

journal_volume

51

pub_type

杂志文章
  • Impact of vitamin A supplementation on prevalence and incidence of xerophthalmia in Nepal.

    abstract:PURPOSE:To assess the impact of vitamin A supplementation at 4-month intervals on the prevalence and incidence of xerophthalmia among preschool-age children. METHODS:A stratified, random sample of 40 wards with 4766 children in Sarlahi district of Nepal was selected to participate in a randomized, controlled, communit...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Katz J,West KP Jr,Khatry SK,Thapa MD,LeClerq SC,Pradhan EK,Pokhrel RP,Sommer A

    更新日期:1995-12-01 00:00:00

  • Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2-Treated Human Tenon's Fibroblasts.

    abstract:PURPOSE:To investigate the pharmacologic effect of tetramethylpyrazine (TMP) on human Tenon's fibroblasts (HTFs), the cells implicated in scarring after filtration surgery. METHODS:Transforming growth factor-β2 (TGF-β2) was used to stimulate a fibrotic phenotype in primary HTFs, and the influence of TMP on the fibroti...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.16-19529

    authors: Cai X,Yang Y,Chen P,Ye Y,Liu X,Wu K,Yu M

    更新日期:2016-09-01 00:00:00

  • Tear evaporation dynamics in normal subjects and subjects with obstructive meibomian gland dysfunction.

    abstract:PURPOSE:To test a newly developed tear evaporimetry system that detects real-time changes in tear evaporation rates and shows the tear film stability in patients with obstructive meibomian gland dysfunction (MGD). METHODS:A ventilated chamber system with high-sensitivity microbalance sensor was used to evaluate tear e...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.02-0170

    authors: Goto E,Endo K,Suzuki A,Fujikura Y,Matsumoto Y,Tsubota K

    更新日期:2003-02-01 00:00:00

  • Effects of mithramycin, mitomycin, daunorubicin, and bleomycin on human subconjunctival fibroblast attachment and proliferation.

    abstract::Scar formation and fibrosis are the most common causes of ultimate glaucoma filtration surgery failure. The authors used Coulter counter, hexosaminidase, and 3H-thymidine assays to evaluate the effects of mithramycin, mitomycin, daunorubicin, and bleomycin on human subconjunctival fibroblast growth in tissue culture. ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Lee DA,Lee TC,Cortes AE,Kitada S

    更新日期:1990-10-01 00:00:00

  • Inhibition of herpes simplex virus replication in the mouse cornea by drug containing immunoliposomes.

    abstract::Monoclonal antibody to HSV glycoprotein D was derivatized with palmitic acid and incorporated into liposomes. These immunoliposomes bound specifically to intact mouse corneas infected with HSV-1 in vitro. Furthermore, in yield reduction assays, anti-gD immunoliposomes loaded with acyclovir proved far more effective at...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Norley SG,Sendele D,Huang L,Rouse BT

    更新日期:1987-03-01 00:00:00

  • Lack of association between interleukin-1 gene cluster polymorphisms and glaucoma in Chinese subjects.

    abstract:PURPOSE:A recent study identified single nucleotide polymorphisms (SNPs) within the IL-1 gene cluster at chromosomal locus 2q13 that were associated with reduced risk for primary open-angle glaucoma (POAG) in whites. The purpose of this study was to investigate the association between IL-1 SNPs and glaucoma in Chinese ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.06-1213

    authors: How AC,Aung T,Chew X,Yong VH,Lim MC,Lee KY,Toh JY,Li Y,Liu J,Vithana EN

    更新日期:2007-05-01 00:00:00

  • Biochemical and biophysical properties of recombinant human interphotoreceptor retinoid binding protein.

    abstract:PURPOSE:Interphotoreceptor retinoid-binding protein (IRBP) binds and transports retinoids and fatty acids in the interphotoreceptor space (IPS). To understand the relationship between the protein structure and its functions requires bulk quantities of human IRBP. The authors sought to produce recombinant human IRBP (rh...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Lin ZY,Si JS,Nickerson JM

    更新日期:1994-09-01 00:00:00

  • Creatine transporter immunolocalization in aged human and detached retinas.

    abstract:PURPOSE:To identify the distribution of creatine transporter (CRT) in the aged human retina and how this expression pattern is modified after retinal detachment. METHODS:An affinity-purified antibody raised against the CRT was used in the immunohistochemical investigation. The anti-CRT antibody was colocalized with ne...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.11-8462

    authors: de Souza CF,Kalloniatis M,Christie DL,Polkinghorne PJ,McGhee CN,Acosta ML

    更新日期:2012-04-18 00:00:00

  • Enhancement of ON-bipolar cell responses of cone electroretinograms in rabbits with the Pro347Leu rhodopsin mutation.

    abstract:PURPOSE:To determine how the different stages of retinal processing change after photoreceptor degeneration in rabbits carrying the Pro347Leu rhodopsin mutation (Tg rabbits). METHODS:Cone electroretinograms (ERGs) were elicited by 150-ms duration stimuli from 13 Tg rabbits at 12 and 24 weeks of age. The ERG recordings...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.11-7611

    authors: Nishimura T,Machida S,Kondo M,Terasaki H,Yokoyama D,Kurosaka D

    更新日期:2011-09-29 00:00:00

  • The balance between proteinases and inhibitors in a murine model of proliferative retinopathy.

    abstract:PURPOSE:To examine the expression of matrix metalloproteinases (MMPs) and their inhibitors during the development of retinal neovascularization (NV) in a mouse model. METHODS:A well-characterized murine model of retinal NV was used to study the expression of specific MMPs (MMP-2, MMP-9, and MT1-MMP) and tissue inhibit...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Majka S,McGuire P,Colombo S,Das A

    更新日期:2001-01-01 00:00:00

  • Effect of intraocular pressure on uveoscleral outflow following cyclodialysis in the monkey eye.

    abstract::Cyclodialysis was performed in both eyes of five cynomolgus monkeys. Two days later the intraocular pressure (IOP) had fallen from 17.7 +/- 0.8 to 7.1 +/- 1.4 mm Hg (P less than 0.001). At that time, both eyes were perfused for 30 min with fluorescein-isothiocyanate (FITC) dextran (MW 70,000), one at 35 mm Hg and the ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Toris CB,Pederson JE

    更新日期:1985-12-01 00:00:00

  • Visual Field Loss in Patients With Diabetes in the Absence of Clinically-Detectable Vascular Retinopathy in a Nationally Representative Survey.

    abstract:Purpose:Neuroretinopathy is increasingly being recognized as an independent cause of vision loss in diabetes. Visual field loss, as detected by frequency doubling technology (FDT)-based visual perimetry, is a sign of neuroretinopathy and occurs in early stages of diabetic retinopathy (DR). Here, we hypothesized that FD...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.19-28063

    authors: Bao YK,Yan Y,Gordon M,McGill JB,Kass M,Rajagopal R

    更新日期:2019-11-01 00:00:00

  • Systemic counterregulatory response of placental growth factor levels to intravitreal aflibercept therapy.

    abstract:PURPOSE:Placental growth factor (PlGF) has been implicated as a contributor to resistance against anti-VEGF therapy. The purpose of the present study was to analyze the systemic levels of PlGF, VEGF-A, and VEGF-B in patients with neovascular age-related macular degeneration (AMD) after treatment with aflibercept, ranib...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章,随机对照试验

    doi:10.1167/iovs.15-16686

    authors: Zehetner C,Bechrakis NE,Stattin M,Kirchmair R,Ulmer H,Kralinger MT,Kieselbach GF

    更新日期:2015-05-01 00:00:00

  • Palisade Endings Have an Exocytotic Machinery But Lack Acetylcholine Receptors and Distinct Acetylcholinesterase Activity.

    abstract:Purpose:The purpose of this work was to test whether palisade endings express structural and molecular features of exocytotic machinery, and are associated with acetylcholine receptors, and enzymes for neurotransmitter breakdown. Methods:Extraocular rectus muscles from six cats were studied. Whole-mount preparations o...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.61.14.31

    authors: Blumer R,Streicher J,Carrero-Rojas G,Calvo PM,de la Cruz RR,Pastor AM

    更新日期:2020-12-01 00:00:00

  • Blood pressure, perfusion pressure, and open-angle glaucoma: the Los Angeles Latino Eye Study.

    abstract:PURPOSE:To examine the cross-sectional relationship between blood pressure, perfusion pressure, and prevalence of open angle glaucoma (OAG) in an adult Latino population. METHODS:Participants aged 40 years and older (N = 6130) from the Los Angeles Latino Eye Study (LALES), a large, population-based study of self-ident...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.08-2956

    authors: Memarzadeh F,Ying-Lai M,Chung J,Azen SP,Varma R,Los Angeles Latino Eye Study Group.

    更新日期:2010-06-01 00:00:00

  • Angiographic Risk Features of Branch Retinal Vein Occlusion Onset as Determined by Optical Coherence Tomography Angiography.

    abstract:Purpose:Examine associations between the vasculature at arteriovenous (AV) crossings and the onset of branch retinal vein occlusion (BRVO). Methods:We included 78 patients with major BRVO, 35 patients with macular BRVO, and 110 controls without BRVO and determined the vessel positions at AV crossings, where the first-...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.61.2.8

    authors: Kogo T,Muraoka Y,Iida Y,Ooto S,Murakami T,Kadomoto S,Iida-Miwa Y,Numa S,Miyake M,Miyata M,Uji A,Tsujikawa A

    更新日期:2020-02-07 00:00:00

  • Heat shock protein 90 is an essential molecular chaperone for nuclear transport of glucocorticoid receptor beta.

    abstract:PURPOSE:Glucocorticoid sensitivity in glaucoma has been attributed to differences in the expression of the two glucocorticoid receptors, GRalpha and GRbeta. GRalpha undergoes steroid-dependent nuclear translocation by associating with a heat shock protein (Hsp)90 multiprotein heterocomplex. The nuclear transport of the...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.05-0697

    authors: Zhang X,Clark AF,Yorio T

    更新日期:2006-02-01 00:00:00

  • Expression of the blue-light receptor cryptochrome in the human retina.

    abstract:PURPOSE:To analyze the patterns of expression of the cryptochromes, CRY1 and CRY2, in the human retina and to correlate expression of these putative blue-light receptors with nonvisual photoreceptor localization. METHODS:CRY1 and CRY2 mRNA expression was analyzed in 4-mm diameter punches of macula and midperipheral hu...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.03-0303

    authors: Thompson CL,Bowes Rickman C,Shaw SJ,Ebright JN,Kelly U,Sancar A,Rickman DW

    更新日期:2003-10-01 00:00:00

  • Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan Lecture.

    abstract::Iron is a potent generator of oxidative damage whose levels increase with age, potentially exacerbating age-related diseases. Several lines of evidence suggest that iron accumulation may be a factor in age-related macular degeneration (AMD). AMD retinas have more iron within the photoreceptors, RPE, and drusen than do...

    journal_title:Investigative ophthalmology & visual science

    pub_type:

    doi:10.1167/iovs.06-0568

    authors: Dunaief JL

    更新日期:2006-11-01 00:00:00

  • Kininogen in autoimmune uveitis: decrease in peripheral blood stream versus increase in target tissue.

    abstract:PURPOSE:Equine recurrent uveitis (ERU) is an incurable disease affecting the inner eye that leads to blindness, through activated T cells that pass the blood-retinal barrier and destroy the retina. Serum markers are a desirable choice for monitoring development of disease, as serum is easy accessible and the markers co...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.09-4094

    authors: Zipplies JK,Hauck SM,Schoeffmann S,Amann B,van der Meijden CH,Stangassinger M,Ueffing M,Deeg CA

    更新日期:2010-01-01 00:00:00

  • The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1.

    abstract:Purpose:Diabetes leads to the downregulation of the retinal Kir4.1 channels and Müller cell dysfunction. The insulin receptor substrate-1 (IRS-1) is a critical regulator of insulin signaling in Müller cells. Circadian rhythms play an integral role in normal physiology; however, diabetes leads to a circadian dysrhythmia...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.18-26045

    authors: Luo Q,Xiao Y,Alex A,Cummins TR,Bhatwadekar AD

    更新日期:2019-05-01 00:00:00

  • Use of EyeCam for imaging the anterior chamber angle.

    abstract:PURPOSE:To compare EyeCam (Clarity Medical Systems, Pleasanton, CA) imaging with gonioscopy for detecting angle closure. METHODS:In this prospective, hospital-based study, subjects underwent gonioscopy by a single observer and EyeCam imaging by a different operator. EyeCam images were graded by two masked observers. T...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.09-4418

    authors: Perera SA,Baskaran M,Friedman DS,Tun TA,Htoon HM,Kumar RS,Aung T

    更新日期:2010-06-01 00:00:00

  • Perceived visual ability for functional vision performance among persons with low vision in the Indian state of Andhra Pradesh.

    abstract:PURPOSE:To determine the distribution of perceived visual ability for functional vision performance among persons with low vision in the Indian state of Andhra Pradesh. METHODS:As part of a population-based epidemiologic study, the Andhra Pradesh Eye Disease Study (APEDS), a 16-item visual function questionnaire was d...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.04-0243

    authors: Nutheti R,Shamanna BR,Krishnaiah S,Gothwal VK,Thomas R,Rao GN

    更新日期:2004-10-01 00:00:00

  • Asymmetric Inter-Eye Progression in Stargardt Disease.

    abstract:Purpose:Asymmetry in disease progression between left and right eyes can occur in Stargardt disease (STGD1), and this needs to be considered in novel therapeutic trials with a fellow-eye paired controlled design. This study investigated the inter-eye discordance of best-corrected visual acuity (BCVA) and progression of...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.16-20963

    authors: Lambertus S,Bax NM,Groenewoud JM,Cremers FP,van der Wilt GJ,Klevering BJ,Theelen T,Hoyng CB

    更新日期:2016-12-01 00:00:00

  • Functional impact of ZEB1 mutations associated with posterior polymorphous and Fuchs' endothelial corneal dystrophies.

    abstract:PURPOSE:To assess the impact of zinc finger E-box binding homeobox 1 (ZEB1) gene mutations associated with posterior polymorphous corneal dystrophy 3 (PPCD3) and Fuchs' endothelial corneal dystrophy (FECD). METHODS:Thirteen of the 27 previously reported ZEB1 truncating mutations associated with PPCD3 and the six previ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.14-15247

    authors: Chung DW,Frausto RF,Ann LB,Jang MS,Aldave AJ

    更新日期:2014-09-04 00:00:00

  • Neuroprotective effects of recombinant T-cell receptor ligand in autoimmune optic neuritis in HLA-DR2 mice.

    abstract:PURPOSE:Optic neuritis (ON) is a condition involving primary inflammation, demyelination, and axonal injury in the optic nerve and leads to apoptotic retinal ganglion cell (RGC) death, which contributes to the persistence of visual loss. Currently, ON has no effective treatment. The goal was to determine the effectiven...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.11-8419

    authors: Adamus G,Brown L,Andrew S,Meza-Romero R,Burrows GG,Vandenbark AA

    更新日期:2012-01-25 00:00:00

  • Saccade adaptation in Williams-Beuren Syndrome.

    abstract:PURPOSE:To investigate the capacity for rapid saccade adaptation in Williams-Beuren Syndrome (WBS), a genetic neurodevelopmental disorder, in which it has been observed that saccadic accuracy is severely reduced. METHODS:Saccade amplitude modification was elicited by backward steps (30% of target eccentricity) during ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.05-0617

    authors: van der Geest JN,Haselen GC,Frens MA

    更新日期:2006-04-01 00:00:00

  • Biochemical activity of reactive oxygen species scavengers do not predict retinal ganglion cell survival.

    abstract:PURPOSE:Retinal ganglion cells (RGCs) die as a result of axonal injury in a variety of optic neuropathies, including glaucoma. Reactive oxygen species (ROS) act as intracellular signaling molecules and initiate apoptosis in nerve growth factor-deprived sympathetic neurons and axotomized RGCs. Determination of the role ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.05-1010

    authors: Schlieve CR,Lieven CJ,Levin LA

    更新日期:2006-09-01 00:00:00

  • Role of Pseudomonas aeruginosa ExsA in penetration through corneal epithelium in a novel in vivo model.

    abstract:PURPOSE:The scarified cornea keratitis model was modified to study Pseudomonas aeruginosa infection of healing corneal epithelium. The new model was then used to study the role of ExsA, a transcriptional activator of P. aeruginosa, in bacterial penetration through injured and healing corneal epithelia. METHODS:Scratch...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.03-0229

    authors: Lee EJ,Evans DJ,Fleiszig SM

    更新日期:2003-12-01 00:00:00

  • Noninvasive measurements of pyridine nucleotide fluorescence from the cornea.

    abstract::The autofluorescence of reduced pyridine nucleotides (NADH and NADPH) and oxidized flavoproteins within the rabbit cornea were noninvasively measured as a function of depth. This was accomplished by combining a corneal specular microscope with a time-shared spectrofluorometer. When either 8 mM sodium pentobarbital or ...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Laing RA,Fischbarg J,Chance B

    更新日期:1980-01-01 00:00:00