Perceived visual ability for functional vision performance among persons with low vision in the Indian state of Andhra Pradesh.

Abstract:

PURPOSE:To determine the distribution of perceived visual ability for functional vision performance among persons with low vision in the Indian state of Andhra Pradesh. METHODS:As part of a population-based epidemiologic study, the Andhra Pradesh Eye Disease Study (APEDS), a 16-item visual function questionnaire was designed and applied to 7363 persons older than 15 years, to record the levels of difficulty perceived by the subjects. Of these, 123 persons were found to have low vision. Rasch analysis was used to convert the ordinal difficulty ratings of these 123 persons into interval measures of perceived visual ability for functional vision. RESULTS:Content validity of the questionnaire was demonstrated by good separation indices (3.17 and 5.44) and high reliability scores (0.91 and 0.97) for person and item parameters. Construct validity was shown with model fit statistics. Criterion validity of the questionnaire was shown by good discrimination among the general vision ratings. The functional situation that required the least visual ability was "reaching an object farther or closer than you thought"; the situation requiring the most visual ability was "recognizing small objects." Bivariate regression analysis determined that for every unit of logMAR visual acuity, perceived visual ability for functional vision decreased by 2.9 logit, which could explain 32% of the variability in the person measure. CONCLUSIONS:The described assessment, across a range of visual problems, is a valid way to measure perceived ability for functional vision in persons with low vision. Perceived visual ability varies with every unit of logarithm of the minimum angle of resolution (logMAR) visual acuity.

authors

Nutheti R,Shamanna BR,Krishnaiah S,Gothwal VK,Thomas R,Rao GN

doi

10.1167/iovs.04-0243

keywords:

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

3458-65

issue

10

eissn

0146-0404

issn

1552-5783

pii

45/10/3458

journal_volume

45

pub_type

杂志文章
  • Gene-rich large deletions are overrepresented in POAG patients of Indian and Caucasian origins.

    abstract:PURPOSE:Large copy number variations (CNV) can contribute to increased burden for neurodegenerative diseases. In this study, we analyzed the genome-wide burden of large CNVs > 100 kb in primary open angle glaucoma (POAG), a neurodegenerative disease of the eye that is the largest cause of irreversible blindness. METHO...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.14-14339

    authors: Kaurani L,Vishal M,Kumar D,Sharma A,Mehani B,Sharma C,Chakraborty S,Jha P,Ray J,Sen A,Dash D,Ray K,Mukhopadhyay A

    更新日期:2014-04-24 00:00:00

  • Measurement of Diurnal Variation in Rod Outer Segment Length In Vivo in Mice With the OCT Optoretinogram.

    abstract:Purpose:To investigate diurnal variation in the length of mouse rod outer segments in vivo. Methods:The lengths of rod inner and outer segments (RIS, ROS) of dark-adapted albino mice maintained on a 12-hour dark:12-hour light cycle with light onset 7 AM were measured at prescribed times (6:30 AM, 11 AM, 3:30 PM) durin...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.61.3.9

    authors: Zhang P,Shibata B,Peinado G,Zawadzki RJ,FitzGerald P,Pugh EN Jr

    更新日期:2020-03-09 00:00:00

  • Somatic mitochondrial DNA deletions accumulate to high levels in aging human extraocular muscles.

    abstract::PURPOSE. Mitochondrial function and the presence of somatic mitochondrial DNA (mtDNA) defects were investigated in extraocular muscles (EOMs) collected from individuals covering a wide age range, to document the changes seen with normal aging. METHODS. Cytochrome c oxidase (COX) and succinate dehydrogenase (SDH) histo...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.09-4660

    authors: Yu-Wai-Man P,Lai-Cheong J,Borthwick GM,He L,Taylor GA,Greaves LC,Taylor RW,Griffiths PG,Turnbull DM

    更新日期:2010-07-01 00:00:00

  • Choroidal hemodynamic changes during isometric exercise in patients with inactive central serous chorioretinopathy.

    abstract:PURPOSE:Imaging studies suggest that the choroidal vasculature may be altered in central serous chorioretinopathy. Little is known, however, about the regulation of ocular blood flow in patients with central serous chorioretinopathy (CSC). The hypothesis for the present study was that choroidal blood flow changes durin...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.05-0268

    authors: Tittl M,Maar N,Polska E,Weigert G,Stur M,Schmetterer L

    更新日期:2005-12-01 00:00:00

  • Anti-retinal antibodies in serum of laser-treated rabbits.

    abstract:PURPOSE:Retinal injuries that affect the photoreceptors and/or the retinal pigment epithelium (RPE) may result in the leakage of retinal proteins into the systemic circulation. This study was designed to determine whether an immune response is elicited after an acute retinal injury resulting in circulating anti-retinal...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.11-7685

    authors: Scott SE,Bouhenni RA,Chomyk AM,Dunmire JJ,Patil J,Nakamura H,Deepak P

    更新日期:2012-04-06 00:00:00

  • Flow cytometry in impression cytology specimens. A new method for evaluation of conjunctival inflammation.

    abstract:PURPOSE:To investigate feasibility and potential uses of flow cytometry in impression cytology as a new procedure to assess and quantify conjunctival inflammation. METHODS:Specimens for cytology were collected by impression from 30 patients with various chronic ocular surface disorders and from 10 normal subjects. Two...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Baudouin C,Brignole F,Becquet F,Pisella PJ,Goguel A

    更新日期:1997-06-01 00:00:00

  • Scanning electron microscopy of human drusen.

    abstract::Drusen are small, yellowish deposits that form under the retinal pigment epithelium (RPE) with senescence or under certain pathological conditions. The present study examined these structures under the scanning electron microscope. Tissue came from four eyes of 66- and 75-year-old donors who demonstrated widespread dr...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Ulshafer RJ,Allen CB,Nicolaissen B Jr,Rubin ML

    更新日期:1987-04-01 00:00:00

  • Lateral phoria at distance: contributions of accommodation.

    abstract::Lateral heterophoria at distance often is cited as an index of tonic vergence, yet recent research has shown that vergence in darkness is more convergent than most measures of phoria. Two experiments were conducted to investigate the possible role of accommodation in this discrepancy. Experiment I compared measures of...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Owens DA,Tyrrell RA

    更新日期:1992-08-01 00:00:00

  • Preventing retinal detachment-associated photoreceptor cell loss in Bax-deficient mice.

    abstract:PURPOSE:To characterize photoreceptor cell apoptosis and cell loss in a mouse model of experimental retinal detachment (RD), and to use the technology of mouse genetics to study the molecular mechanisms underlying RD-associated photoreceptor degeneration. METHODS:Retinal detachments were created in adult wild-type and...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.03-0827

    authors: Yang L,Bula D,Arroyo JG,Chen DF

    更新日期:2004-02-01 00:00:00

  • Monitoring glaucomatous visual field progression: the effect of a novel spatial filter.

    abstract:PURPOSE:To assess the impact of a novel visual field spatial filtering technique on the detection of glaucomatous progression. METHODS:One hundred ninety-eight ocular hypertensive (OHT) and 21 control subjects were examined prospectively (1994-2001) with regular full-threshold Humphrey visual field (VF) testing. VF pr...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.06-0576

    authors: Strouthidis NG,Scott A,Viswanathan AC,Crabb DP,Garway-Heath DF

    更新日期:2007-01-01 00:00:00

  • Quality of life in patients with leber hereditary optic neuropathy.

    abstract:PURPOSE:Leber hereditary optic neuropathy (LHON) is an inherited mitochondrial optic neuropathy characterized by bilateral, severe loss of central vision. In this study, the first formal assessment was conducted of visual disability in affected and unaffected individuals from molecularly confirmed LHON pedigrees. METH...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.08-3166

    authors: Kirkman MA,Korsten A,Leonhardt M,Dimitriadis K,De Coo IF,Klopstock T,Griffiths PG,Hudson G,Chinnery PF,Yu-Wai-Man P

    更新日期:2009-07-01 00:00:00

  • Beta-adrenergic stimulation of Na+, K+, Cl- cotransport in fetal nonpigmented ciliary epithelial cells.

    abstract:PURPOSE:The effects of adrenergic agonists and antagonists on Na+, K+, Cl- cotransport in fetal human nonpigmented ciliary epithelial (NPE) cells were investigated. METHODS:86Rb+ as a marker for K+ was used to study ouabain-insensitive, bumetanide-sensitive 86Rb+ uptake in cultured NPE monolayers. Cyclic adenosine mon...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Crook RB,Riese K

    更新日期:1996-05-01 00:00:00

  • Angioscotometry with the scanning laser ophthalmoscope. Comparison of the effect of different wavelengths.

    abstract:PURPOSE:Angioscotomas are scotomata caused by vessel shadows. Their extent may be influenced by physiological and pharmacologic conditions and disease. In this study, the authors quantified angioscotomas in normal subjects using a fundus perimetry technique with a scanning laser ophthalmoscope. They further investigate...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Remky A,Beausencourt E,Elsner AE

    更新日期:1996-10-01 00:00:00

  • Unilateral gonadectomy does not alter contralateral intraocular pressure in rabbit eyes.

    abstract::The purpose of this study was to determine whether unilateral gonadectomy caused any change in intraocular pressure. Repeated measurements in 22 male and nine female rabbits after unilateral gonadectomy were made by three different methods of determining intraocular pressure. We were unable to find a decrease in intra...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: van den Pol A,Maul E,Sears M

    更新日期:1977-03-01 00:00:00

  • Mechanical properties of the human posterior lens capsule.

    abstract:PURPOSE:To investigate mechanical properties of the human posterior lens capsule. METHODS:Twenty-five human donor eyes were obtained from an eye bank. The age of the donors ranged from 1 to 94 years. Test specimens were prepared as tissue rings from posterior lens capsules by means of excimer laser. Capsular thickness...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.02-0096

    authors: Krag S,Andreassen TT

    更新日期:2003-02-01 00:00:00

  • The effects of citrate on the adherence of neutrophils to nylon fibers in vitro.

    abstract::The therapeutic effect of citrate on alkali-burned eyes is thought to be the result of inhibition of PMN activities while ascorbate apparently stimulates the production of new collagen by scorbutic fibroblasts. Attachment of PMNs to the vascular endothelium is the initial PMN response to mediators and must occur befor...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Pfister RR,Haddox JL,Snyder TL

    更新日期:1988-06-01 00:00:00

  • Advanced glycation end products in vitreous: Structural and functional implications for diabetic vitreopathy.

    abstract:PURPOSE:Advanced glycation end products (AGEs) form irreversible cross-links with many macromolecules and have been shown to accumulate in tissues at an accelerated rate in diabetes. In the present study, AGE formation in vitreous was examined in patients of various ages and in patients with diabetes. Ex vivo investiga...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Stitt AW,Moore JE,Sharkey JA,Murphy G,Simpson DA,Bucala R,Vlassara H,Archer DB

    更新日期:1998-12-01 00:00:00

  • Effects of dietary n-3 fatty acid deficiency and repletion in the guinea pig retina.

    abstract:PURPOSE:To investigate the nature and reversibility of biochemical and functional changes in the retina encountered over a single generation of dietary n-3 polyunsaturated fatty acid deficiency in guinea pigs. METHODS:Dunkin-Hartley guinea pigs were fed for 16 weeks after weaning with diets supplemented with safflower...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Weisinger HS,Vingrys AJ,Bui BV,Sinclair AJ

    更新日期:1999-02-01 00:00:00

  • A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants.

    abstract:PURPOSE:Mutations in the coding region of the OPTN gene are associated with certain glaucomas. Although the function of the optineurin protein is yet to be elucidated, the most common mutation, E50K, is associated with a severe phenotype. This study explores some functional features of optineurin and its mutants. METH...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.06-0834

    authors: Chalasani ML,Radha V,Gupta V,Agarwal N,Balasubramanian D,Swarup G

    更新日期:2007-04-01 00:00:00

  • Human macula investigated in vivo with polarization-sensitive optical coherence tomography.

    abstract:PURPOSE:To investigate a depolarizing layer that is visible in polarization-sensitive optical coherence tomography (PS-OCT) images of the retina. To identify this layer and characterize its depolarizing effect quantitatively. METHODS:Ten healthy human subjects (mean age, 31 +/- 8 years) and two patients with RPE disea...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.05-1589

    authors: Pircher M,Götzinger E,Findl O,Michels S,Geitzenauer W,Leydolt C,Schmidt-Erfurth U,Hitzenberger CK

    更新日期:2006-12-01 00:00:00

  • The Urokinase Receptor-Derived Peptide UPARANT Recovers Dysfunctional Electroretinogram and Blood-Retinal Barrier Leakage in a Rat Model of Diabetes.

    abstract:Purpose:The activation of the urokinase-type plasminogen activator and its receptor system is associated with retinal diseases. Among peptide inhibitors of this system, UPARANT acts by preventing the onset of pathologic signs of neovascular ocular diseases. We investigated whether systemic UPARANT may act in a therapeu...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.17-21593

    authors: Cammalleri M,Locri F,Marsili S,Dal Monte M,Pisano C,Mancinelli A,Lista L,Rusciano D,De Rosa M,Pavone V,Bagnoli P

    更新日期:2017-06-01 00:00:00

  • Vitreoretinal ablation with the 193-nm excimer laser in fluid media.

    abstract:PURPOSE:To ablate retina and vitreous membranes using the 193-nm argon fluoride excimer laser in a fluid medium. METHODS:A special delivery system for the 193-nm excimer laser was developed that enabled the delivery of the laser into high-absorption liquid environments. The system was tested on the retina in an in vit...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Palanker D,Hemo I,Turovets I,Zauberman H,Fish G,Lewis A

    更新日期:1994-10-01 00:00:00

  • Landmark-driven fundus perimetry using the scanning laser ophthalmoscope.

    abstract:PURPOSE:To present a new method of performing scanning laser ophthalmoscope perimetry that compensates for eye movements so that the correct retinal location is tested even if fixation changes. This allows for accurate testing of patients with central scotomas and for repeating testing longitudinally at the same retina...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Sunness JS,Schuchard RA,Shen N,Rubin GS,Dagnelie G,Haselwood DM

    更新日期:1995-08-01 00:00:00

  • Retinoblastoma: tissue culture lines and monoclonal antibody studies.

    abstract::Retinoblastoma patients have cellular and humoral reactivity towards antigens expressed on retinoblastoma cells. We report the ultrastructural, cytogenetic, and immunologic features of four new retinoblastoma derived tissue culture cell lines. Studies with hybridoma produced monoclonal antibodies demonstrate that thes...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:

    authors: Char DH,Wood IS,Huhta K,Rand N,Morita CT,Howes EL Jr

    更新日期:1984-01-01 00:00:00

  • Multiplex bead analysis of vitreous humor of patients with vitreoretinal disorders.

    abstract:PURPOSE:Vitreoretinal disorders are frequently characterized by increased vitreous levels of cellular mediators, including cytokines, chemokines, and growth factors. The study was conducted to investigate whether multiplex bead analysis could identify disease-specific profiles of these mediators in a variety of vitreor...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.06-1358

    authors: Banerjee S,Savant V,Scott RA,Curnow SJ,Wallace GR,Murray PI

    更新日期:2007-05-01 00:00:00

  • Benefits and side effects of different vegetable oil vectors on apoptosis, oxidative stress, and P2X7 cell death receptor activation.

    abstract:PURPOSE:Ocular side effects in patients using eye drops may be due to intolerance to the vector used in eye drops. Castor oil is the commonly used lipophilic vector but has been shown to be cytotoxic. Effects on cells of four oils (olive, camelina, Aleurites moluccana, maize) were compared with those of castor oil in h...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.07-0229

    authors: Said T,Dutot M,Christon R,Beaudeux JL,Martin C,Warnet JM,Rat P

    更新日期:2007-11-01 00:00:00

  • Endoscopic vitrectomy improves outcomes of Seoul-type keratoprosthesis exchange in rabbit model.

    abstract:PURPOSE:To investigate the efficacy of an endoscopic vitrectomy in Seoul-type keratoprosthesis (S-Kpro) exchange procedures. METHODS:Nine S-Kpro-implanted rabbit eyes were enrolled in the S-Kpro exchange. Six eyes underwent an antecedent vitrectomy by an endoscopic system and then the S-Kpro exchange (endoscopy group)...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.08-1802

    authors: Lee SM,Kim MK,Oh JY,Heo JW,Shin MS,Lee MS,Wee WR,Lee JH

    更新日期:2008-10-01 00:00:00

  • Photoreceptor layer topography in children with leber congenital amaurosis caused by RPE65 mutations.

    abstract:PURPOSE:To study the topography of photoreceptor loss early in the course of Leber congenital amaurosis (LCA) caused by RPE65 mutations. METHODS:Young patients with RPE65-LCA (n = 9; ages, 6-17 years) were studied with optical coherence tomography (OCT) in a wide region of central retina. Outer nuclear layer (ONL) thi...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.08-2121

    authors: Jacobson SG,Cideciyan AV,Aleman TS,Sumaroka A,Windsor EA,Schwartz SB,Heon E,Stone EM

    更新日期:2008-10-01 00:00:00

  • Quantitative Analysis of the Displacement of the Anterior Visual Pathway by Pituitary Lesions and the Associated Visual Field Loss.

    abstract:PURPOSE:To evaluate quantitatively the relationship between the displacement of anterior visual pathway structures by pituitary tumors and visual field damage with the goal of improving diagnosis and management. METHODS:Subjects had pituitary macroadenomas and both magnetic resonance imaging (MRI) and static perimetry...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.16-19410

    authors: Boland MV,Lee IH,Zan E,Yousem DM,Miller NR

    更新日期:2016-07-01 00:00:00

  • TAK1 inhibition accelerates cellular senescence of retinal pigment epithelial cells.

    abstract:PURPOSE:Oxidative stress and cellular senescence are known to contribute to the development of AMD; however, the mechanism is not fully understood. This study investigated the role of TGF-β-activated kinase 1 (TAK1) in the senescence of RPE cells as a model for the development of dry AMD. METHODS:Cultured human RPE ce...

    journal_title:Investigative ophthalmology & visual science

    pub_type: 杂志文章

    doi:10.1167/iovs.14-14349

    authors: Dvashi Z,Green Y,Pollack A

    更新日期:2014-08-12 00:00:00