Recovery from Strongyloides venezuelensis infection in Lewis rats is associated with a strong Th2 response.

abstract：:In this study, supplementation with the probiotic Saccharomyces boulardii promoted a reduction in intensity of infection by Toxocara canis and modulates cytokines mRNA expression in experimentally infected mice. IL-12 gene transcription had 40-fold increase in S. boulardii supplemented uninfected mice and sevenfold in...

journal_title：Parasite immunology

authors： de Avila LF,de Leon PM,de Moura MQ,Berne ME,Scaini CJ,Leivas Leite FP

更新日期：2016-05-01 00:00:00

abstract：:Isotype/subclass-specific antibody responses to adult Onchocerca volvulus extract (OvAg) were assessed by both ELISA and immunoblotting for a group of putatively immune individuals (PIs, n = 29) from a hyperendemic area in Ecuador and for a group of infected individuals (INFs, n = 470) from the same regions. As a grou...

journal_title：Parasite immunology

authors： Stewart GR,Elson L,Araujo E,Guderian R,Nutman TB,Bradley JE

更新日期：1995-07-01 00:00:00

abstract：:Human recombinant tumour necrosis factor (rTNF) enhanced monoclonal IgE-dependent eosinophil-mediated cytotoxicity to schistosomula of Schistosoma japonicum in a dose-dependent manner. The enhancing effect of rTNF was also observed for the antibody-dependent cytotoxicity of a human eosinophilic leukemia cell line, EoL...

journal_title：Parasite immunology

authors： Janecharut T,Hata H,Takahashi H,Yoshida S,Saito H,Kojima S

更新日期：1992-11-01 00:00:00

abstract：:The present study was designed to investigate the role of neutrophils during the development of Schistosoma japonicum egg granulomas, in C57BL/6 and CBA mice. Laid eggs were implanted into the liver and monoclonal antibody, RB6-8C5, was used to eliminate neutrophils. After daily antibody treatment between days 9 and 1...

journal_title：Parasite immunology

authors： Hirata M,Hara T,Kage M,Fukuma T,Sendo F

更新日期：2002-09-01 00:00:00

abstract：:Soluble extracts from salivarian trypanosomes (Trypanosoma brucei brucei, T. evansi and T. congolense) were shown to be capable of inducing murine tumour necrosis factor (mTNF) secretion, both in vivo and in vitro, whereas the soluble extract of an intracellular trypanosome (T. cruzi) failed to do so. Furthermore, the...

journal_title：Parasite immunology

authors： Magez S,Lucas R,Darji A,Songa EB,Hamers R,De Baetselier P

更新日期：1993-11-01 00:00:00

abstract：:Leishmania donovani, the causative parasite of Visceral Leishmaniasis (VL), deviously manipulates host monocytes/macrophages to ensure its survival. Although monocytes/macrophages from patients with VL have demonstrated an impaired oxidative burst and antigen presentation, an unanswered yet pertinent question remains ...

journal_title：Parasite immunology

authors： Roy S,Mukhopadhyay D,Mukherjee S,Moulik S,Chatterji S,Brahme N,Pramanik N,Goswami RP,Saha B,Chatterjee M

更新日期：2018-07-01 00:00:00

abstract：:Toxoplasma gondii is a worldwide protozoan parasite which causes severe disease in congenitally infected children and in immunocompromised patients. Besides the well-defined cytoplasmic and membrane antigens of tachyzoites, we felt that excreted/secreted antigens could play a major role in the immune response. We firs...

journal_title：Parasite immunology

authors： Darcy F,Deslee D,Santoro F,Charif H,Auriault C,Decoster A,Duquesne V,Capron A

更新日期：1988-09-01 00:00:00

abstract：:Serum antibody responses of mice exposed to Philippine isolates of Schistosoma japonicum have been analysed by immunoprecipitation of exogenously radiolabelled antigens extracted from adult worms. Attention was focused on labelled protein antigens differentially recognized by sera of mice that differ genetically in th...

journal_title：Parasite immunology

authors： Mitchell GF,Beall JA,Cruise KM,Tiu WU,Garcia EG

更新日期：1985-03-01 00:00:00

abstract：:Helper T cell cytokine and antibody responses were investigated in mice after infection with Babesia microti (King strain). Infection of CBA mice with 106 parasitized erythrocytes resulted in the development of a transitory high parasitaemia which peaked 14 days post infection (DPI), and was resolved at 24 DPI. Th1 re...

journal_title：Parasite immunology

authors： Chen D,Copeman DB,Burnell J,Hutchinson GW

更新日期：2000-02-01 00:00:00

abstract：:The protein-energy malnutrition (PEM) and visceral leishmaniasis (VL) are important problems of public health, which affect millions of people worldwide. Currently, it has been accepted that the immunity or susceptibility to infect-parasitic diseases are directly related to the nutritional status of the host. However,...

journal_title：Parasite immunology

authors： Malafaia G

更新日期：2009-10-01 00:00:00

abstract：:The platelets from normal rats interact with microfilariae of Dipetalonema viteae in vitro in the presence of antibodies leading to the killing of the parasite. The antibody involved in this reaction is identified as IgE because the absorption of immune rat serum on anti-rat IgE column or the pretreatment of platelets...

journal_title：Parasite immunology

authors： Haque A,Cuna W,Bonnel B,Capron A,Joseph M

更新日期：1985-09-01 00:00:00

abstract：:Parasitic nematodes are constantly exposed to the immune effector mechanisms of their hosts. One strategy of the worms to cope with these defence reactions is the secretion of modulatory proteins that down-regulate cell-mediated immune responses. We analysed the proliferation of mesenteric lymph node cells of mice inf...

journal_title：Parasite immunology

authors： Rzepecka J,Lucius R,Doligalska M,Beck S,Rausch S,Hartmann S

更新日期：2006-09-01 00:00:00

abstract：:The number of individuals catching schistosomiasis has increased with the popularity of 'primitive tourism' in Africa. Highly immunogenic material originating from the intestine of intravascular adult schistosomes gives rise to an antibody response making possible early identification of infected individuals using ser...

journal_title：Parasite immunology

authors： Thors C,Linder E

更新日期：1998-10-01 00:00:00

abstract：:Lysates of the haematoprotozoa Trypanosoma brucei or Plasmodium berghei stimulated murine peritoneal exudate cells to release a mediator, which suppressed lipoprotein lipase activity in differentiating 3T3-L1 preadipocytes. The parasite-induced mediator suppressed the activity of cell surface lipoprotein lipase up to ...

journal_title：Parasite immunology

authors： Hotez PJ,Le Trang N,Fairlamb AH,Cerami A

更新日期：1984-05-01 00:00:00

abstract：:Chagas' disease or American trypanosomiasis due to Trypanosoma cruzi has existed at least since the time of the Inca empire and contributes significantly to cardiovascular morbidity and mortality in several countries of this continent. Due to the fundamental role of human class II molecules polymorphic residues in the...

journal_title：Parasite immunology

authors： Fernandez-Mestre MT,Layrisse Z,Montagnani S,Acquatella H,Catalioti F,Matos M,Balbas O,Makhatadze N,Dominguez E,Herrera F,Madrigal A

更新日期：1998-04-01 00:00:00

abstract：:Antigen specific and concanavalin A (Con A)-induced lymphocyte blastogenesis responses were monitored in the spleens of rats infected with Plasmodium berghei. Con A responses were depressed only at the time of peak parasitaemia. The antigen specific blastogenesis response was either not in evidence, or at a low level ...

journal_title：Parasite immunology

authors： Raybourne R,Desowitz RS,Sanghirun C

更新日期：1984-09-01 00:00:00

abstract：:Research on infectious agents as a possible cause of schizophrenia has become prominent in the past decade. Toxoplasma gondii has emerged as a prime candidate for a variety of reasons; (i) many studies have reported that individuals with schizophrenia, compared to controls, have a higher prevalence of antibodies to T....

journal_title：Parasite immunology

authors： Yolken RH,Dickerson FB,Fuller Torrey E

更新日期：2009-11-01 00:00:00

abstract：:Dipetalonema viteae (Filarioidea) infections were established in inbred strains of mice by the s.c. implantation of adult female worms and the resulting microfilaraemia and adult worm survival monitored. BALB/c mice were the most susceptible strain examined, showing a high level microfilaraemia of approximately 6 mont...

journal_title：Parasite immunology

authors： Storey N,Wakelin D,Behnke JM

更新日期：1985-07-01 00:00:00

abstract：:The development of a malaria vaccine is a priority for improved and sustained malaria control. Optimal use of a vaccine in Africa will only be achieved if it can be delivered through the Expanded Programme of Immunization (EPI). We have completed a trial of the peptide vaccine SPf66 in Tanzanian infants, given alongsi...

journal_title：Parasite immunology

authors： Galindo CM,Acosta CJ,Schellenberg D,Aponte JJ,Roca A,Oettli A,Urassa H,Armstrong Schellenberg J,Kahigwa E,Ascaso C,Mshinda H,Lwilla F,Vidal J,Menendez C,Tanner M,Alonso PL

更新日期：2000-09-01 00:00:00

abstract：:We demonstrated recently that immunization with recombinant Neospora caninum profilin (rNcPRO) induces limited protection and a regulatory T-cell response in mice. The aim of this study was to evaluate the immune response elicited by rNcPRO in cattle and assess a strategy to enhance its immunogenicity, combining the a...

journal_title：Parasite immunology

authors： Mansilla FC,Quintana ME,Cardoso NP,Capozzo AV

更新日期：2016-11-01 00:00:00

abstract：:The course of primary infections with Nippostrongylus brasiliensis was followed in nude (CBH/R nu/nu) and heterozygote (CBH/R nu/+) rats. In both nude and heterozygote rats peak egg production by N. brasiliensis occurred on days 7 and 8 post-infection. However, whereas in heterozygote rats egg production declined rapi...

journal_title：Parasite immunology

authors： Smith NC,Ovington KS,Bryant C

更新日期：1991-11-01 00:00:00

abstract：AIMS:Industrial growth has increased the exposure to endocrine disruptor compounds (EDCs) in all organisms. Bisphenol A (BPA), an EDC, has been demonstrated to be involved in the susceptibility to parasite infections. However, few studies have analysed this connection in more depth. The aim of this study was to determi...

journal_title：Parasite immunology

authors： Nava-Castro KE,Togno-Peirce C,Palacios-Arreola MI,Del Rio-Araiza VH,Hernandez-Bello R,Morales Montor J

更新日期：2020-09-01 00:00:00

abstract：:The natural site of infection for T. gondii is the mucosal surface of the intestine, so the protective immunity obtained after natural infection with T. gondii points to the importance of developing a vaccine that stimulates mucosal defences. In this study, an aroA- and aroD- attenuated strain of Salmonella typhimuriu...

journal_title：Parasite immunology

authors： Cong H,Gu QM,Jiang Y,He SY,Zhou HY,Yang TT,Li Y,Zhao QL

更新日期：2005-01-01 00:00:00

abstract：:Toxoplasma gondii-specific murine CD4+ T cell clone 3Tx9 belongs to the Th1 subtype by virtue of secreting high levels of interleukin(IL)-2, interferon-gamma and tumor necrosis factor without producing IL4 and IL10. To characterize the clonal antigen, Toxoplasma lysate-was separated by SDS-PAGE and probed in T cell bl...

journal_title：Parasite immunology

authors： Reichmann G,Dlugonska H,Fischer HG

更新日期：1997-05-01 00:00:00

abstract：:African trypanosomes are well known for their ability to avoid immune elimination by switching the immunodominant variant surface glycoprotein (VSG) coat during infection. However, antigenic variation is only one of several means by which trypanosomes manipulate the immune system of their hosts. In this article, the r...

journal_title：Parasite immunology

authors： Mansfield JM,Paulnock DM

更新日期：2005-10-01 00:00:00

abstract：:We have cloned the cDNA of TBA-1, the Nematode polyprotein allergen (NPA) of Toxocara canis and found it to be most similar to ABA-1, the Ascaris NPA, on the basis of amino acid sequence. We could study the antigenic properties of an E-coli synthesized fusion protein prepared with the cloned gene since no glycosylatio...

journal_title：Parasite immunology

authors： Yahiro S,Cain G,Butler JE

更新日期：1998-08-01 00:00:00

abstract：:Trypanosoma congolense is one of the main species responsible for Animal African Trypanosomosis (AAT). As preventive vaccination strategies for AAT have been unsuccessful so far, investigating the mechanisms underlying vaccine failure has to be prioritized. In T. brucei and T. vivax infections, recent studies revealed...

journal_title：Parasite immunology

authors： Obishakin E,de Trez C,Magez S

更新日期：2014-05-01 00:00:00

abstract：:Helminth parasites induce a strong Th2 response, characterized by high levels of IgE and elevated signature cytokines such as IL-5. As many global deworming programmes are underway, there is concern that this might lead to emergence of Th1-mediated pathologies when the counterbalancing helminth-induced Th2 response is...

journal_title：Parasite immunology

authors： de Ruiter K,Tahapary DL,Wammes LJ,Wiria AE,Hamid F,van Lieshout L,Smit JWA,Houwing-Duistermaat JJ,Sartono E,Supali T,Yazdanbakhsh M

更新日期：2017-06-01 00:00:00

abstract：:The protective effect of specific vaccination against Plasmodium berghei (P. berghei) was compared in terms of survival percentage in DBA/2, C3H, outbred albino mice and in two lines of mice produced by selective breeding for either high or low antibody responsiveness to sheep erythrocyte (H and L lines respectively)....

journal_title：Parasite immunology

authors： Heumann AM,Bucci A,Stiffel C,Casaglia O,Zenobi P,Biozzi G

更新日期：1983-03-01 00:00:00

abstract：:A limiting dilution microculture system was optimized to quantify the frequency of Theileria parva-specific cytotoxic T lymphocyte precursors (CTLp) in peripheral blood mononuclear cells (PBMC) from immune cattle. Optimal results were obtained with responder cell input levels ranging from 2 x 10(4)/well to 6.25 x 10(2...

journal_title：Parasite immunology

authors： Taracha EL,Goddeeris BM,Scott JR,Morrison WI

更新日期：1992-03-01 00:00:00