Could Helicobacter pylori play an important role in axonal type of Guillain-Barré syndrome pathogenesis?

Abstract:

:In this case-control study, ELISA and Western blot with whole bacterial protein lysate were performed on serum and cerebrospinal fluid (CSF) of 15 controls and 15 patients. According to Griffin subtypes, 10 of our patients were in acute inflammatory demyelinating polyradiculoneuropathy (AIDP) group, 3 in acute motor axonal neuropathy (AMAN) group, and 2 in acute motor sensory axonal neuropathy (AMSAN) subtype. 86.6% of patients were positive for Helicobacter pylori (H. pylori) IgG. Serum anti-H. pylori IgG of patients and controls were significantly different. CSF anti-H. pylori IgG was significantly higher in patients than controls. In patients, the titer of anti-H. pylori IgG in serum was significantly higher than CSF, which may indicate extra-neural antibody synthesis. CSF IgG titer was higher in patients having axonal pattern. Western blot was positive in CSF of 13 patients and negative in all controls. There was a correlation between the number of antibody types against H. pylori particles and the titer of anti-H. pylori IgG in CSF and serum. Also, antibody against cytotoxin associated protein (CagA) was associated with primary axonal pattern. The association between the presence of anti-CagA and primary axonal pattern, is in favor of the relation between axonal neuropathy and H. pylori infection.

journal_name

Clin Neurol Neurosurg

authors

Ghabaee M,Ghanbarian D,Brujeni GN,Bokaei S,Siavoshi F,Gharibzadeh S

doi

10.1016/j.clineuro.2009.11.008

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

193-8

issue

3

eissn

0303-8467

issn

1872-6968

pii

S0303-8467(09)00305-9

journal_volume

112

pub_type

杂志文章
  • Holocord astrocytomas in childhood.

    abstract::In this case report, we present a patient with a low-grade holocord astrocytoma. Therapy and its consequences are discussed. ...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/0303-8467(90)90066-e

    authors: Vles JS,Grubben CP,van Ooy A,Weil EH

    更新日期:1990-01-01 00:00:00

  • Surgical outcomes in traumatic brain injuries with bilateral mass occupying lesions. Analysis of prognostic factors.

    abstract:INTRODUCTION:Traumatic brain injury is a silent epidemic with major impacts on national productivity as it affects the economically productive age group. Bilateral injuries are usually severe with no clearly defined predictors of outcome as per current available literature. METHODS:We retrospectively assessed 102 cons...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2020.106017

    authors: Yeole U,Krishnakumar M,Gopalakrishna KN,Sekar A,Sadashiva N,Shukla D

    更新日期:2020-09-01 00:00:00

  • Ipilimumab treatment associated pituitary hypophysitis: clinical presentation and imaging diagnosis.

    abstract::Ipilimumab is an immunomodulating drug for use in treatment of unresectable or metastatic melanoma with autoimmune lymphocytic hypophysitis as a reported complication. We describe three recent cases of ipilimumab associated autoimmune hypophysitis (IAH) at our institution, and provide a selected literature review show...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.clineuro.2014.06.011

    authors: Chodakiewitz Y,Brown S,Boxerman JL,Brody JM,Rogg JM

    更新日期:2014-10-01 00:00:00

  • Is there a difference in outcomes of patients with idiopathic intracranial hypertension with the choice of cerebrospinal fluid diversion site: a single centre experience.

    abstract:UNLABELLED:The visual and headache outcomes in patients with idiopathic intracranial hypertension (IIH) undergoing cerebrospinal fluid diversion with a lumboperitoneal (LPS) or ventriculoperitoneal shunting (VPS) have not been well reported. The aims of this study were to: (a) to assess outcomes of CSF diversion in IIH...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2011.02.008

    authors: Tarnaris A,Toma AK,Watkins LD,Kitchen ND

    更新日期:2011-07-01 00:00:00

  • Facioscapulohumeral muscular dystrophy: the impact of genetic research.

    abstract::Recent developments in genetic research have led to the localization and identification of the causative gene defect in a large number of neurological diseases. This paper describes some of the basic principles of molecular genetics and the strategies that have been followed in the search for the gene for facioscapulo...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1016/0303-8467(93)90086-v

    authors: Brouwer OF,Wijmenga C,Frants RR,Padberg GW

    更新日期:1993-03-01 00:00:00

  • Follow-up magnetic resonance imaging in Hallervorden-Spatz disease.

    abstract::Bilateral high signal emitting areas in the globus pallidus surrounded by low signal emitting areas have been described as a typical MRI finding in Hallervorden-Spatz disease (HSD). We made a diagnosis of HSD in an 11-year-old girl with progressive dystonia of 4 years duration who showed these typical MRI abnormalitie...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1016/0303-8467(92)90023-v

    authors: Brouwer OF,Laboyrie PM,Peters AC,Vielvoye GJ

    更新日期:1992-01-01 00:00:00

  • Clinical experiences with spontaneous intracranial hypotension: a proposal of a diagnostic approach and treatment.

    abstract:OBJECTIVE:We analyzed our clinical experience with patients with intracranial hypotension and developed a strategic model for the diagnosis mainly using Radioisotope (RI) cisternography and treatment of spontaneous intracranial hypotension (SIH). METHODS AND MATERIALS:We retrospectively analyzed our clinical experienc...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2010.12.015

    authors: Yoon SH,Chung YS,Yoon BW,Kim JE,Paek SH,Kim DG

    更新日期:2011-06-01 00:00:00

  • Pedicle fracture of the axis: report of two cases and a review of literature.

    abstract::Clinical and neuroradiological features of two cases with unilateral pedicle fractures of C2 were presented and the literature of this rare traumatic fracture was reviewed. Both 37- and 57-year-old woman had traffic accident and were admitted in our institute. Both patients were neurologically free except for neck pai...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.clineuro.2004.06.001

    authors: Cokluk C,Takayasu M,Yoshida J

    更新日期:2005-02-01 00:00:00

  • Non-traumatic brachial plexopathies, clinical, radiological and neurophysiological findings from a tertiary centre.

    abstract:OBJECTIVE:To establish the clinical characteristics, aetiology, neuro-physiological characteristics, imaging findings and other investigations in a cohort of patients with non-traumatic brachial plexopathy (BP). METHODS:A 3-year retrospective study of patients with non-traumatic BP identified by electromyography (EMG)...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2007.05.010

    authors: Mullins GM,O'Sullivan SS,Neligan A,Daly S,Galvin RJ,Sweeney BJ,McNamara B

    更新日期:2007-10-01 00:00:00

  • Pain and functional improvement effects of methylene blue injection on the soft tissue around fusion site after traumatic thoracolumbar fixation: A double-blind, randomized placebo-controlled study.

    abstract:OBJECTIVE:Fractures of the thoracolumbar spine can cause pain, long-term reductions in quality of life (QOL), and neural deficits. The aim of this study was to investigate the effects of methylene blue (MB) on preventing postoperative pain and improving QOL in patients with throracolumbar fractures undergoing posterior...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.clineuro.2016.08.018

    authors: Farrokhi MR,Yazdanpanah H,Gholami M,Farrokhi F,Mesbahi AR

    更新日期:2016-11-01 00:00:00

  • Dementia associated with hyperphosphatemic tumoral calcinosis.

    abstract::Hyperphosphatemic tumoral calcinosis (HTC) is a rare inherited metabolic disorder manifested by pararticular calcification and hyperphosphatemia, caused by an elevated renal phosphate reabsorption threshold and elevated serum 1,25-dihydroxyvitamin D levels. The disorder usually affects African-American subjects, but h...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(98)00010-9

    authors: Beck DA,Gray L,Lyles KW

    更新日期:1998-06-01 00:00:00

  • Time course of cerebrospinal fluid inflammatory biomarkers and relationship to 6-month neurologic outcome in adult severe traumatic brain injury.

    abstract:OBJECTIVE:Activation of the inflammatory cascade is a known pathophysiologic process in severe traumatic brain injury (TBI) with yet non-standardized scientific data regarding relationship to outcome. The understanding of the time course of expression of cerebrospinal fluid (CSF) biomarker levels following severe TBI i...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2016.06.009

    authors: Nwachuku EL,Puccio AM,Adeboye A,Chang YF,Kim J,Okonkwo DO

    更新日期:2016-10-01 00:00:00

  • Pseudohypoxic brain swelling after elective clipping of an unruptured anterior communicating artery aneurysm.

    abstract::A case of pseudohypoxic brain swelling, a newly defined entity, is described. The patient experienced generalized seizures and did not awake initially after a seemingly uneventful elective craniotomy for clipping of an unruptured anterior communicating artery aneurysm. Neuroimaging findings demonstrated diffuse brain ...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2009.08.007

    authors: Yokota H,Yokoyama K,Miyamoto K,Nishioka T

    更新日期:2009-12-01 00:00:00

  • Atypical presentation of an extradural hematoma on the grounds of a temporal arachnoid cyst.

    abstract::We report a 56-year-old man, with atypical presentation of an extradural hematoma caused by head injury after a fall. The presence of a temporal arachnoid cyst on the grounds of temporal lobe agenesis altered the clinical image of this man, causing only mild symptoms where an otherwise acute neurologic deterioration w...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(03)00022-2

    authors: Boviatsis EJ,Maratheftis NL,Kouyialis AT,Sakas DE

    更新日期:2003-07-01 00:00:00

  • Validation of diagnostic algorithm to differentiate between tuberculous meningitis and acute bacterial meningitis.

    abstract:BACKGROUND:Discrimination between tuberculous and acute bacterial meningitis is difficult by clinical features alone and laboratory methods may only supplement the clinical suspicion. We aimed to validate the diagnostic criteria by Thwaites et al. [1] and construct our own diagnostic predictors based on the clinical an...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2011.12.033

    authors: Vibha D,Bhatia R,Prasad K,Srivastava MV,Tripathi M,Kumar G,Singh MB

    更新日期:2012-07-01 00:00:00

  • Red blood cell distribution width is an independent predictor of mortality in patients with aneurysmal subarachnoid hemorrhage.

    abstract:OBJECTIVES:This study was performed to evaluate the association between red blood cell distribution width (RDW) and 3-month mortality in patients with aneurysmal subarachnoid hemorrhage. PATIENTS AND METHODS:This observational study was performed from March 2007 to May 2017 in an emergency department. The baseline cha...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2018.06.044

    authors: Hong DY,Kim SY,Kim JY,Kim JW

    更新日期:2018-09-01 00:00:00

  • Tardive gait.

    abstract::Tardive dyskinesia (TD) is a hyperkinetic movement disorder induced by dopamine receptor blocking drugs (DRBDs). TD typically presents with stereotypy or dystonia, but may also cause akathisia, myoclonus, or tremor. However, no detailed reports of gait abnormalities have been documented. We report three patients expos...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2007.09.013

    authors: Kuo SH,Jankovic J

    更新日期:2008-02-01 00:00:00

  • Complications of the chronic subdural hematoma.

    abstract::Eighty three chronic subdural hematomas, obtained by surgery or by necropsy, were examinated. The patient age distribution curve of the non-complicated operative cases showed the highest incidence in the first year of life and also a moderate increase in the elderly group. Recurrent hemorrhage in the walls and in the ...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(76)80051-0

    authors: Reuck JD,Roels H,Eecken H

    更新日期:1976-01-01 00:00:00

  • Subarachnoid hemorrhage in systemic lupus erythematosus: systematic review and report of three cases.

    abstract:OBJECTIVE:Systemic lupus erythematosus (SLE) is an autoimmune disorder of multifactorial etiology with a broad range of clinical manifestations. Cerebral disorders such as psychosis, seizures and cerebrovascular accidents are commonly described in SLE patients. Subarachnoid hemorrhage (SAH) presents a higher incidence ...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.clineuro.2014.10.018

    authors: Torné R,Rodríguez-Hernández A,Bernard T,Arikan Abelló F,Vilalta Castan J,Sahuquillo J

    更新日期:2015-01-01 00:00:00

  • Endosellar meningiomas: report of 2 cases and review of the literature.

    abstract::Two cases of endosellar meningiomas are presented. The clinical and radiological picture is not always sufficiently specific to distinguish meningiomas from other types of sellar lesions, but pre-operative diagnosis is of fundamental importance in choosing the best surgical approach. In both cases, the transsphenoidal...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/0303-8467(95)00085-2

    authors: Talacchi A,Benvenuto F,Lombardo C,Bricolo A

    更新日期:1996-02-01 00:00:00

  • Compromised motor imagery ability in individuals with multiple sclerosis and mild physical disability: an ERP study.

    abstract:BACKGROUND:Motor imagery (MI) impairment has been reported in individuals with multiple sclerosis (MS). The present study was designed to investigate neural evidence for MI impairment and its relationship to working memory in MS patients. METHODS:The study participants included 24 early stage MS patients (age: 22-40/m...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2013.04.002

    authors: Tabrizi YM,Mazhari S,Nazari MA,Zangiabadi N,Sheibani V,Azarang S

    更新日期:2013-09-01 00:00:00

  • Inter observer agreement in the assessment of the motor response of the Glasgow 'coma' scale.

    abstract::The motor response of the Glasgow 'coma' scale is readily learned by nurses and doctors. It can be used as a reliable indicator of changes in the state of a comatose patient, as there is a high agreement rate between different observers. ...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(78)80067-5

    authors: Braakman R,Avezaat CJ,Maas AI,Roel M,Schouten HJ

    更新日期:1977-01-01 00:00:00

  • A single institutional outcome analysis of Gamma Knife radiosurgery for single or multiple brain metastases.

    abstract::Although Gamma Knife stereotactic radiosurgery (SRS) is widely used for metastatic brain tumors, optimal patient selection and treatment strategy continue to be investigated. The aim of this study was to provide treatment results with Gamma Knife SRS and to establish prognostic factors. Of the 54 patients treated from...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(00)00117-7

    authors: Nakagawa K,Tago M,Terahara A,Aoki Y,Sasaki T,Kurita H,Shin M,Kawamoto S,Kirino T,Otomo K

    更新日期:2000-12-01 00:00:00

  • Efficacy of spinal cord stimulation for neuropathic pain following idiopathic acute transverse myelitis: a case report.

    abstract::Spinal cord stimulation (SCS) involves the electrical stimulation of dorsal structures within the spinal cord, and is the most widespread application of neurostimulation for the relief of chronic pain. Idiopathic acute transverse myelitis (IATM) is an acute monophasic lesion of the spinal cord that presents with sympt...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(99)00012-8

    authors: Laffey JG,Murphy D,Regan J,O'Keeffe D

    更新日期:1999-06-01 00:00:00

  • Peripheral vascular disease as remote ischemic preconditioning, for acute stroke.

    abstract:OBJECTIVES:Remote ischemic preconditioning (RIPC) is a powerful endogenous mechanism whereby a brief period of ischemia is capable of protecting remote tissues from subsequent ischemic insult. While this phenomenon has been extensively studied in the heart and brain in animal models, little work has been done to explor...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2013.07.038

    authors: Connolly M,Bilgin-Freiert A,Ellingson B,Dusick JR,Liebeskind D,Saver J,Gonzalez NR

    更新日期:2013-10-01 00:00:00

  • Megadolicho vascular malformation of the intracranial arteries.

    abstract::A patient is presented suffering a hemiparesis. Megadolicho-vascular malformation of the intracranial part of the internal carotid arteries and some of its branches and of the basilar artery was suggested by CT and confirmed by angiography. The value of CT compared with angiography in relation to intracranial megadoli...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(81)80004-2

    authors: Lodder J,Janevski B,van der Lugt PJ

    更新日期:1981-01-01 00:00:00

  • Muscle activation features of the osteoarthritic knee with patellar lateral subluxation.

    abstract:OBJECTIVE:The aim of the study was to compare the muscle activation feature of vastus medialis obliquus (VMO) and vastus lateralis (VL) between the osteoarthritic knee patients with patellar lateral subluxation (Group 1B) and without patellar lateral subluxation (Group 1A). METHODS:Isokinetic muscle strength of the kn...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/S0303-8467(15)30009-3

    authors: Tang SF,Wu CK,Chen CH,Chen JT,Tang AC,Wu SH

    更新日期:2015-02-01 00:00:00

  • Familial spastic paraplegia: evidence for a fourth locus.

    abstract::Autosomal dominant familial spastic paraparesis (AD-FSP) is a genetically heterogeneous disorder of the central nervous system characterized by a progressive spasticity of the legs. One gene causing AD-FSP (FSP1) has recently been mapped to chromosome 14q, another gene (FSP2) to chromosome 2p, and a third gene (FSP3) ...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(97)00602-1

    authors: Bruyn RP,van Veen MM,Kremer H,Scheltens PH,Padberg GW

    更新日期:1997-05-01 00:00:00

  • Cranial nerve involvement in childhood polyarteritis nodosa.

    abstract::Amongst a variety of neurological manifestations of childhood polyarteritis nodosa, cranial nerve involvement is unusual. We report 4 cases with cranial nerve palsies in a series of 36 biopsy-proven patients. Two cases presented with IIIrd nerve palsy alone, one with right IIIrd and left IVth nerve palsy, and one with...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/0303-8467(92)90111-f

    authors: Topaloglu R,Besbas N,Saatci U,Bakkaloglu A,Oner A

    更新日期:1992-01-01 00:00:00

  • The correlation of helios and neuropilin-1 frequencies with parkinson disease severity.

    abstract:OBJECTIVES:Parkinson disease (PD), a neurodegenerative disease, has also some immunologic basis in which several regulatory factors, like Helios and Neuropilin-1 (NRP-1) may show some roles in its pathogenesis. We aimed to evaluate the circulatory frequency of T regulatory cells (Tregs) expressing Helios and NRP-1 in P...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2020.105833

    authors: Daneshvar Kakhaki R,Kouchaki E,Dadgostar E,Behnam M,Tamtaji OR,Nikoueinejad H,Akbari H

    更新日期:2020-05-01 00:00:00