Abstract：
:Hyperphosphatemic tumoral calcinosis (HTC) is a rare inherited metabolic disorder manifested by pararticular calcification and hyperphosphatemia, caused by an elevated renal phosphate reabsorption threshold and elevated serum 1,25-dihydroxyvitamin D levels. The disorder usually affects African-American subjects, but has also been described in Caucasians and Hispanics. Vascular calcifications and angioid streaks have been reported to be associated with the disorder; however, dementia has not been previously reported. Our medical center has followed two African-American siblings, with HTC for over 30 years, who have developed dementia at 56 years and 67 years of age. Neither man has been hypertensive, however, magnetic resonance imaging (MRI) scans in both cases revealed multiple periventricular infarcts, suggestive of infarcts caused by vascular calcification in the central nervous system. These two brothers with HTC suggest that periventricular infarcts with dementia may be a long term complication of this disorder.
journal_name
Clin Neurol Neurosurgjournal_title
Clinical neurology and neurosurgeryauthors
Beck DA,Gray L,Lyles KWdoi
10.1016/s0303-8467(98)00010-9subject
Has Abstractpub_date
1998-06-01 00:00:00pages
121-5issue
2eissn
0303-8467issn
1872-6968pii
S0303846798000109journal_volume
100pub_type
杂志文章abstract：:The frequency of positive results of four conventional provocative tests (Phalen sign, Tinel sign, wrist extension and pressure provocation test) was evaluated in 179 patients with clinical and electrophysiological findings consistent with idiopathic carpal tunnel syndrome (CTS), 147 control subjects and 39 patients w...
journal_title：Clinical neurology and neurosurgery
pub_type： 临床试验,杂志文章
doi：10.1016/s0303-8467(01)00140-8
更新日期：2001-10-01 00:00:00
abstract：:Disulfiram in generally accepted maintenance doses in alcoholism may produce a rather severe polyneuropathy. In addition to the 39 literature cases, 5 personal patients were examined. Detailed clinical findings are given and the frequent permanent sequelae are emphasized. In 2 patients sural nerve biopsies were studie...
journal_title：Clinical neurology and neurosurgery
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doi：10.1016/0303-8467(84)90070-2
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journal_title：Clinical neurology and neurosurgery
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doi：10.1016/j.clineuro.2007.03.003
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/s0303-8467(89)80030-7
更新日期：1989-01-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/0303-8467(91)90007-c
更新日期：1991-01-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2009.06.012
更新日期：2009-11-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.clineuro.2020.106208
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2010.11.020
更新日期：2011-05-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/0303-8467(92)90102-9
更新日期：1992-01-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2019.04.025
更新日期：2019-07-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2012.02.037
更新日期：2012-09-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2015.12.010
更新日期：2016-02-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2009.09.003
更新日期：2010-01-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2011.06.011
更新日期：2011-12-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2018.03.007
更新日期：2018-05-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2005.10.002
更新日期：2006-10-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2007.09.023
更新日期：2008-02-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2012.09.006
更新日期：2013-07-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2020.106201
更新日期：2020-11-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2014.06.033
更新日期：2014-10-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.clineuro.2010.05.011
更新日期：2010-11-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2020.106161
更新日期：2020-10-01 00:00:00
abstract：:Endovascular therapy has been used as an alternative treatment for vasospasm following subarachnoid hemorrhage. The effectiveness and safety of endovascular therapy are still controversial. We performed a systematic review and meta-analysis to identify any advantage of endovascular therapy over traditional medical tre...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.clineuro.2017.09.016
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVE:The aim of this hospital-based study is to get an insight into the efficacy and tolerability of antiepileptic drugs (AED) in Omani epileptic patients. PATIENTS AND METHODS:All Omani patients (aged 14 years and above) suffering from epileptic seizures for at least 2 years and followed-up by board-certified ne...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2005.08.007
更新日期：2006-09-01 00:00:00
abstract：OBJECTIVES:Neurosurgical audits are an important part of improving the safety, efficiency and quality of care but require considerable resources, time, and funding. To that end, the advent of the Artificial Intelligence-based algorithms offered a novel, more economically viable solution. The aim of the study was to eva...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2020.105732
更新日期：2020-05-01 00:00:00
abstract：:32 patients with the chronic progressive form of the multiple sclerosis were treated with high doses of cyclophosphamide and prednisone during 20 days, to produce immunosuppression. The effect of treatment was measured by scoring three different Kurtzke scales just before treatment (1), just after treatment (II), and ...
journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/s0303-8467(75)80007-2
更新日期：1975-01-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2020.105785
更新日期：2020-06-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.clineuro.2005.05.006
更新日期：2006-06-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2018.02.038
更新日期：2018-05-01 00:00:00
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journal_title：Clinical neurology and neurosurgery
pub_type： 杂志文章
doi：10.1016/j.clineuro.2013.06.003
更新日期：2013-10-01 00:00:00
