WITHDRAWN: Membrane-based amplification in hearing.

abstract：:Laser scanning confocal microscopy was used to determine the distribution of actin, spectrin and tubulin in whole mounts of the organ of Corti of guinea pig, monkey, rat and chinchilla. Actin, spectrin and tubulin were localized in all cell types in the auditory epithelium. No specialized cytoskeletal organization of ...

journal_title：Hearing research

authors： Raphael Y,Athey BD,Wang Y,Lee MK,Altschuler RA

更新日期：1994-06-01 00:00:00

abstract：:In recent years, new designs of cochlear implant electrodes have been introduced in an attempt to improve efficiency and performance by locating stimulation sites closer to spiral ganglion neurons and deeper into the scala tympani. The goal of this study was to document insertion depth, intracochlear position and inse...

journal_title：Hearing research

authors： Wardrop P,Whinney D,Rebscher SJ,Roland JT Jr,Luxford W,Leake PA

更新日期：2005-05-01 00:00:00

abstract：:Previous investigations have shown that a subset of inferior colliculus neurons, which have been designated type O units, respond selectively to isolated features of the cat's head-related transfer functions (HRTFs: the directional transformation of a free-field sound as it propagates from the head to the eardrum). Ba...

journal_title：Hearing research

authors： May BJ,Anderson M,Roos M

更新日期：2008-04-01 00:00:00

abstract：:Tinnitus is most often initiated by modality specific otopathologic disturbances affecting peripheral and central auditory pathways. However, there is growing evidence indicating that the anatomical location generating tinnitus occurs at sites different from the initial pathology. Support for this notion is found in i...

journal_title：Hearing research

authors： Cacace AT

更新日期：2003-01-01 00:00:00

abstract：:The auditory system can encode interaural delays in highpass-filtered complex sounds by phase locking to their slowly modulating envelopes. Spectrotemporal analysis of interaurally time-delayed highpass waveforms reveals the presence of a concomitant interaural level cue. The current study systematically investigated ...

journal_title：Hearing research

authors： Hsieh IH,Petrosyan A,Gonçalves ÓF,Hickok G,Saberi K

更新日期：2011-07-01 00:00:00

abstract：:Ototoxicity is a dose-limiting side effect of chemotherapeutic treatment with cisplatin. In a series of experiments on neonatal rat cochlear organotypic cultures, the extent of damage induced by a broad range of cisplatin treatment concentrations was examined. Paradoxically, it was found that hair cell loss was greate...

journal_title：Hearing research

authors： Ding D,He J,Allman BL,Yu D,Jiang H,Seigel GM,Salvi RJ

更新日期：2011-12-01 00:00:00

abstract：:It is well known that quality of hearing decreases with increasing age due to changes in the peripheral or central auditory pathway. Along with the decrease in the number of neurons the neurotransmitter profile is also affected in the various parts of the auditory system. Particularly, changes in the inhibitory neuron...

journal_title：Hearing research

authors： Pal I,Paltati CRB,Kaur C,Shubhi Saini,Kumar P,Jacob TG,Bhardwaj DN,Roy TS

更新日期：2019-06-01 00:00:00

abstract：:The basilar papilla length increases systematically with body mass for 41 species from more than 10 avian orders and this relation does not differ between phylogenetic groups. Audiograms of 25 non-strigiform and 12 owl species, normalized relative to best frequency and best threshold, were used to compare audiogram sh...

journal_title：Hearing research

authors： Gleich O,Langemann U

更新日期：2011-03-01 00:00:00

abstract：:In the cochlea, outer hair cells (OHCs) and Deiters' cells most likely contribute to the generation of active cochlear mechanics. The presence of ATP receptors on these cells indicates that endogenous ATP may have a role in cochlear mechanics. To explore this possibility, the effects of ATP antagonists were studied bo...

journal_title：Hearing research

authors： Skellett RA,Chen C,Fallon M,Nenov AP,Bobbin RP

更新日期：1997-09-01 00:00:00

abstract：:Sensorineural hearing loss, which is often caused by degeneration of hair cells in the auditory epithelium, is permanent because lost hair cells are not replaced. Several conceptual approaches can be used to place new hair cells in the auditory epithelium. One possibility is to enhance proliferation of non-sensory cel...

journal_title：Hearing research

authors： Minoda R,Izumikawa M,Kawamoto K,Zhang H,Raphael Y

更新日期：2007-10-01 00:00:00

abstract：:Perception of objects in the scene around us is effortless and intuitive, yet entails profound computational challenges. Progress has been made in understanding some mechanisms by which the brain encodes the boundaries and surfaces of visual objects. However, in the auditory domain, these mechanisms are poorly underst...

journal_title：Hearing research

authors： McMullan AR,Hambrook DA,Tata MS

更新日期：2013-10-01 00:00:00

abstract：:Voltage-dependent K+ channels in the basolateral membrane of hair cells in guinea-pig cochlea might contribute to the non-linear current-voltage relationships in these hair cells and, thereby, to generation of the extracellular summating potential (SP). To evaluate the role of K+ channels in the generation of the SP t...

journal_title：Hearing research

authors： van Emst MG,Klis SF,Smoorenburg GF

更新日期：1995-08-01 00:00:00

abstract：:The inner ear contains receptor cells that oscillate spontaneously, generating waves that propagate backward in the cochlea, ultimately causing sound to be radiated into the ear canal--the spontaneous otoacoustic emissions (SOAEs). Except in rare conditions, these internally generated signals appear to go unheard. The...

journal_title：Hearing research

authors： Norena A,Micheyl C,Durrant J,Chéry-Croze S,Collet L

更新日期：2002-09-01 00:00:00

abstract：:Eighth nerve endings and neuronal types in the nucleus magnocellularis were analyzed in the red-eared turtle (Chrysemys scripta elegans). One group of turtles had horseradish peroxidase (HRP) injected into the surgically exposed inner ear. Following injection the animals survived for 3-5 days and then their 8th nerve ...

journal_title：Hearing research

authors： Browner RH,Marbey D

更新日期：1988-06-01 00:00:00

abstract：:Progress in amino acid sequencing of two low-molecular weight acidic proteins of unknown function which are present at high concentrations in the organ of Corti is reported. These two proteins, provisionally termed OCP1 and OCP2, were originally demonstrated by two-dimensional polyacrylamide gel electrophoresis; their...

journal_title：Hearing research

authors： Thalmann I,Suzuki H,McCourt DW,Comegys TH,Thalmann R

更新日期：1993-01-01 00:00:00

abstract：:A hyperpolarization-activated current (termed I[h]) is believed to provide a pacemaker depolarization in sinoatrial node cells and in some central and peripheral neurons. In the present study, we examined if such an inward cation current exists in primary auditory neurons using the whole-cell patch-clamp technique. A ...

journal_title：Hearing research

authors： Chen C

更新日期：1997-08-01 00:00:00

abstract：:The middle ear is a sophisticated and complex structure with a variety of functions, yet a delicate organ prone to injuries due to various reasons. Both, understanding and reconstructing its functions has always been an important topic for researchers from medical and technical background. Currently, human temporal bo...

journal_title：Hearing research

authors： Kuru I,Maier H,Müller M,Lenarz T,Lueth TC

更新日期：2016-10-01 00:00:00

abstract：:Exposure of the auditory system to either continuous or interrupted nontraumatic noises, often collectively referred to as priming exposures, has been shown, in a number of experimental paradigms, to reduce the susceptibility of the auditory system to noise-induced hearing and sensory cell loss from a subsequent traum...

journal_title：Hearing research

authors： Hamernik RP,Ahroon WA

更新日期：1999-11-01 00:00:00

abstract：:Strial marginal cells are known to take up and metabolize glucose as their main source of metabolic energy. The membrane transport mechanisms for glucose uptake into strial marginal cells, however, are largely unknown. Two types of glucose transporters in mammalian cells have been described, the facilitated glucose tr...

journal_title：Hearing research

authors： Takeuchi S,Ando M

更新日期：1997-12-01 00:00:00

abstract：:Reported are the results of analyses of three-channel Lissajous trajectories (3CLTs) of the auditory brain stem responses (ABRs) in a human subject in whom a focal lesion of the brain stem was caused by stereotactic radiosurgery, the 'gamma knife'. The surgery caused total destruction of the right inferior colliculus....

journal_title：Hearing research

authors： Durrant JD,Martin WH,Hirsch B,Schwegler J

更新日期：1994-01-01 00:00:00

abstract：:To rehabilitate profoundly deaf patients who are not suitable for cochlear implants, central auditory prostheses have been implanted. To compare two possible electrode configurations - penetrating and surface ones - electrical stimulation of the cochlear nucleus with both types of arrays was tested on guinea pigs and ...

journal_title：Hearing research

authors： Liu X,McPhee G,Seldon HL,Clark GM

更新日期：1997-12-01 00:00:00

abstract：:Electrically evoked auditory brainstem response (EABR) recordings were made from 38 humans implanted with one of three cochlear prostheses, and from 25 cats. Recognizable auditory potentials were identified in 27 of the profoundly deaf implanted subjects. In both cats and humans EABR waveform morphology and magnitude ...

journal_title：Hearing research

authors： van den Honert C,Stypulkowski PH

更新日期：1986-01-01 00:00:00

abstract：:Speech is central to human life. As such, any delay or impairment in receptive speech processing can have a profoundly negative impact on the social and professional life of a person. Thus, being able to assess the integrity of speech processing in different populations is an important goal. Current standardized asses...

journal_title：Hearing research

authors： Di Liberto GM,Lalor EC

更新日期：2017-05-01 00:00:00

abstract：:Masking patterns were measured for hearing-impaired subjects with varying degrees of hearing loss. In one set of conditions, three subjects were tested using narrowband noise ('noise') and sinusoidal ('tone') maskers and narrowband noise signals. The maskers had centre frequencies of 0.25, 0.5, 1.0 and 4.0 kHz and lev...

journal_title：Hearing research

authors： Alcántara JI,Moore BC

更新日期：2002-03-01 00:00:00

abstract：:Cochlear outer hair cell (OHC) electromotility is associated with the cell's lateral wall. The lateral wall contains two distinct membranes: the plasma membrane (PM) and the subsurface cisternae (SSC). We explored biophysical characteristics of these lipid structures using membrane-specific fluorescent dyes. We have p...

journal_title：Hearing research

authors： Oghalai JS,Tran TD,Raphael RM,Nakagawa T,Brownell WE

更新日期：1999-09-01 00:00:00

abstract：:Although speech understanding is highly variable amongst cochlear implants (CIs) subjects, the remarkably high speech recognition performance of many CI users is unexpected and not well understood. Numerous factors, including neural health and degradation of the spectral information in the speech signal of CIs, likely...

journal_title：Hearing research

authors： Zheng Y,Escabí M,Litovsky RY

更新日期：2017-08-01 00:00:00

abstract：:Tone-burst-evoked compound action potentials (CAP) from the guinea pig round window (RW) are altered by DC current injection through the RW. The CAP waveform consists of a series of interleaved negative and positive peaks (N(1), P(1), N(2), P(2) etc.) of decreasing amplitude. During positive DC current injection (arou...

journal_title：Hearing research

authors： Brown DJ,McMahon CM,Patuzzi RB

更新日期：2004-04-01 00:00:00

abstract：:Certain hair cells of fish exhibit strong immunoreactivity to an S-100 antibody. By their spatial locations in the utricle and saccule, these hair cells appear to possess a relatively short kinocilium and a roughly ovoid cell shape. In the utricle, these cells are predominantly located in the striola. In the saccule, ...

journal_title：Hearing research

authors： Saidel WM,Presson JC,Chang JS

更新日期：1990-08-01 00:00:00

abstract：:Noise trauma, aging, and ototoxicity preferentially damage the outer hair cells of the inner ear, leading to increased hearing thresholds and poorer frequency resolution. Whereas outer hair cells make synaptic connections with less than 10% of afferent auditory nerve fibers (type-II), inner hair cells make connections...

journal_title：Hearing research

authors： Lobarinas E,Salvi R,Ding D

更新日期：2013-08-01 00:00:00

abstract：:The tension fibroblasts of the spiral ligament of the mammalian cochlea are thought to create radial tension on the basilar membrane. Their postnatal development was investigated in the gerbil (Meriones unguiculatus) with confocal fluorescence microscopy using phallotoxin as a specific marker for F-actin. In the adult...

journal_title：Hearing research

authors： Kuhn B,Vater M

更新日期：1997-06-01 00:00:00