Paternity testing: blood group systems and DNA analysis by variable number of tandem repeat markers.

Abstract:

:Two recent paternity cases are reported. In the first case of paternity exclusion, deoxyribonucleic acid (DNA) restriction fragment length polymorphisms (RFLPs) on variable number of tandem repeat (VNTR) loci with multiple alleles were informative, as well as established systems of red blood antigens, red cell enzymes, serum proteins, and human leukocyte antigens. In the second case, in which both the alleged father and the first wife were deceased, the paternal genotype was determined by using genetic markers from the second wife and four children, which then were compared with the paternal alleles of the child in question, the plaintiff in this case. The high probability of paternity (0.999,998,7) made us conclude that the man probably was the actual father. The DNA analysis by VNTR probes appears to be quite valuable in the study of paternity cases.

journal_name

J Forensic Sci

authors

Akane A,Matsubara K,Shiono H,Yuasa I,Yokota S,Yamada M,Nakagome Y

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

1217-25

issue

5

eissn

0022-1198

issn

1556-4029

journal_volume

35

pub_type

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