Abstract：
:Acoustic communication in male Chorthippus biguttulus is a suitable behavioral model to explore the physiological effects and underlying molecular mechanisms of identified neuropeptides. Proctolin plays a modulatory role in a neuronal circuit controlling sexual behavior in these insects. Activation of proctolin receptors triggers courtship singing (the second level of excitation in sexual behavior) that is preceded by call singing triggered by muscarinic acetylcholine receptor activation. The pharmacological studies presented here revealed that the Phospholipase C pathway was involved in courtship singing since neomycin and Li(+) strongly inhibited proctolin-stimulated singing. In addition, injecting phorbol ester into proctolin-sensitive neural sites only elicited stridulation. This confirms that proteinkinase C can mediate the effects of Phospholipase C activation in this model. These results partially clarify the molecular mechanisms in the decision making brain center that controls sexual behavior in these insects.
journal_name
Eur J Pharmacoljournal_title
European journal of pharmacologyauthors
Vezenkov SR,Danalev DLdoi
10.1016/j.ejphar.2009.08.010subject
Has Abstractpub_date
2009-10-01 00:00:00pages
57-60issue
1-3eissn
0014-2999issn
1879-0712pii
S0014-2999(09)00681-5journal_volume
619pub_type
杂志文章abstract：:Canine femoral arteries responded to acetylcholine with relaxations; these were abolished in potassium free solution, restored by potassium or rubidium but not by cesium or amonium. Potassium and rubidium were equipotent in inducing ouabain-sensitive relaxation, while amonium and cesium were less potent. The results (...
journal_title：European journal of pharmacology
pub_type： 杂志文章
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journal_title：European journal of pharmacology
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journal_title：European journal of pharmacology
pub_type： 杂志文章
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journal_title：European journal of pharmacology
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journal_title：European journal of pharmacology
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journal_title：European journal of pharmacology
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journal_title：European journal of pharmacology
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doi：10.1016/j.ejphar.2007.06.053
更新日期：2007-10-31 00:00:00
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journal_title：European journal of pharmacology
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/j.ejphar.2007.10.068
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/j.ejphar.2009.03.024
更新日期：2009-05-01 00:00:00
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/0014-2999(90)90604-5
更新日期：1990-05-03 00:00:00
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/j.ejphar.2008.08.010
更新日期：2008-11-12 00:00:00
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/j.ejphar.2003.11.006
更新日期：2004-01-26 00:00:00
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/j.ejphar.2006.01.067
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/s0014-2999(97)00129-5
更新日期：1997-05-01 00:00:00
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journal_title：European journal of pharmacology
pub_type： 杂志文章,评审
doi：10.1016/s0014-2999(01)01319-x
更新日期：2001-10-19 00:00:00
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/0014-2999(75)90305-2
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/0014-2999(92)90782-y
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journal_title：European journal of pharmacology
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journal_title：European journal of pharmacology
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更新日期：2005-05-02 00:00:00
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journal_title：European journal of pharmacology
pub_type： 杂志文章
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更新日期：1983-08-05 00:00:00
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journal_title：European journal of pharmacology
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doi：10.1016/j.ejphar.2013.10.005
更新日期：2013-11-15 00:00:00
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journal_title：European journal of pharmacology
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doi：10.1016/j.ejphar.2018.03.015
更新日期：2018-05-15 00:00:00
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journal_title：European journal of pharmacology
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doi：10.1016/j.ejphar.2017.03.054
更新日期：2017-05-15 00:00:00
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/0922-4106(91)90029-h
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/0014-2999(95)00009-a
更新日期：1995-03-24 00:00:00
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/0014-2999(95)00573-4
更新日期：1995-11-14 00:00:00
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journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/0014-2999(88)90276-2
更新日期：1988-11-08 00:00:00
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journal_title：European journal of pharmacology
pub_type： 杂志文章
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更新日期：2020-02-15 00:00:00
abstract：:Depression is very common in asthmatic patients and may increases risk for morbidity and mortality. The present work aimed to investigate the protective effect of fluoxetine, on behavioral and biochemical changes, associated with ovalbumin (OVA) - induced bronchial asthma and depression in rats. Rats were sensitized w...
journal_title：European journal of pharmacology
pub_type： 杂志文章
doi：10.1016/j.ejphar.2018.08.026
更新日期：2018-10-15 00:00:00
