Abstract：
:The shortage of adequate organ donors remains a great challenge in clinical lung transplantation. With increasing experience in the medical management and surgical technique of lung transplantation, gradual expansion of the criteria for lung donor selection has occurred with beneficial effects on the donor pool. Interest in donation after cardiac death also is increasing as the gap increases between donors and the needs of listed patients. Successful use of these new sources of lungs depends on the accurate assessment and prediction of transplanted lung function. Promising techniques for lung assessment and diagnostics include investigating key genes associated with graft failure or good graft performance using molecular approaches, and ex vivo evaluation. Further studies are needed to answer remaining questions about the best technique and solution to reperfuse human lungs for several hours without edema formation. As the predictive ability to discern good from injured donor lungs improves, strategies to repair donor lungs become increasingly important. Prolonged normothermic EVLP seems to be a platform on which many reparative strategies can be realized. With these new methods for assessing and resuscitating lungs accurately, it is hoped that inroads will be made toward providing every listed patient a chance for successful lung transplantation.
journal_name
Thorac Surg Clinjournal_title
Thoracic surgery clinicsauthors
Yeung JC,Cypel M,Waddell TK,van Raemdonck D,Keshavjee Sdoi
10.1016/j.thorsurg.2009.02.006subject
Has Abstractpub_date
2009-05-01 00:00:00pages
261-74issue
2eissn
1547-4127issn
1558-5069pii
S1547-4127(09)00004-8journal_volume
19pub_type
杂志文章,评审abstract：:Adequate lymphadenectomy represents a fundamental procedure in lung cancer surgery for accurate staging and potential survival benefit. Various techniques are used in current surgical practice for the intraoperative lymph node removal associated with pulmonary resection, without definitive indications concerning the p...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2011.12.001
更新日期：2012-05-01 00:00:00
abstract：:Arterial thoracic outlet syndrome is rare and may be associated with a bony anomaly. Patient presentation can range from mild arm discoloration and claudication to severe limb-threatening ischemia. For patients with subclavian artery dilation without secondary complications, thoracic outlet decompression and arterial ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2020.09.006
更新日期：2021-02-01 00:00:00
abstract：:The benefits derived from comprehensive PR, when applied to patients who have lung cancer, should have significant impact on both survival and health status. Because PR is known to improve exercise capacity, it is reasonable to expect that this treatment modality may provide more patients with a potential cure. In add...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2007.10.003
更新日期：2008-02-01 00:00:00
abstract：:Development of postpneumonectomy empyema with bronchopleural fistula is a life-threatening condition that requires prompt action. Although measures should be taken to prevent bronchopleural fistula at time of pneumonectomy, many patients experience this complication. Management focuses on drainage of the pleural space...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2018.05.008
更新日期：2018-08-01 00:00:00
abstract：:Recurrent symptomatic paraesophageal hernias (PEHs) can lead to significant morbidity if untreated. Surgical treatment of recurrent PEH can pose a great challenge. Several different surgical options are available and need to be considered on an individual basis. Before embarking on the repair of a recurrent hernia, a ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2019.07.011
更新日期：2019-11-01 00:00:00
abstract：:Standardized clinical care pathways for the investigation of patients with lung cancer allow for a reduction in the time interval between suspicion of lung cancer and treatment, lower costs, increased patient satisfaction, and quality of care. It may also be associated with a modest increase in survival. ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2013.01.012
更新日期：2013-05-01 00:00:00
abstract：:Professional oaths and codes do not establish a firm basis for the obligation to treat all patients and they provide little or no clear guidance about whether patient nonadherence exempts a physician from a longstanding and still prevalent tradition in surgery supports a strong obligation to one's established patients...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2005.06.012
更新日期：2005-11-01 00:00:00
abstract：:Gastroesophageal reflux disease (GERD) is a well-defined disease characterized by symptoms or complications caused by an abnormal amount of GER, which is a retrograde movement of gastric contents into the esophagus. Laryngopharyngeal reflux (LPR) is a subset of GERD and given its own identity, because the main symptom...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2011.08.001
更新日期：2011-11-01 00:00:00
abstract：:This article summarizes the pertinent points of tracheal and bronchial anatomy, including the relationships to surrounding structures. Tracheal and bronchial anatomy is essential knowledge for the thoracic surgeon, and an understanding of the anatomic relationships surrounding the airway is crucial to the safe perform...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2006.12.006
更新日期：2007-11-01 00:00:00
abstract：:Nerve injuries can cause substantial morbidity after thoracic surgical procedures. These injuries are preventable, provided that the surgeon has a thorough understanding of the anatomy and follows important surgical principles. When nerve injuries occur, it is important to recognize the options available in the immedi...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2015.07.012
更新日期：2015-11-01 00:00:00
abstract：:Esophageal perforation has historically been a devastating condition resulting in high morbidity and mortality. The use of endoluminal therapies to treat esophageal leaks and perforations has grown exponentially over the last decade and offers many advantages over traditional surgical intervention in the appropriate c...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2018.07.002
更新日期：2018-11-01 00:00:00
abstract：:MPM is an uncommon disease with limited treatment options. Early diagnosis, a standardized staging system, early referral to centers experienced in MPM, and efforts to develop collaborative multicenter trials are essential to improving treatment for patients with MPM. Efforts to manage this malignancy, which is projec...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2004.06.009
更新日期：2004-11-01 00:00:00
abstract：:Staging of malignant pleural mesothelioma has been challenging because of a paucity of cases and poor survival. At least 5 staging systems were proposed before 1990 until the first consensus system was published in 1995. This system used tumor, node, metastasis designations and borrowed heavily from parenchymal lung c...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2020.07.001
更新日期：2020-11-01 00:00:00
abstract：:A thorough knowledge of thoracic anatomy is of fundamental importance to the thoracic surgeon. Surface anatomy is an often-neglected component of traditional topographic anatomic teaching, but a proper understanding of the relationship of surface features to deeper structures is invaluable in the clinical assessment o...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2006.12.002
更新日期：2007-11-01 00:00:00
abstract：:Despite a prospective randomized trial that reported decreased locoregional recurrence for the intentional use of sublobar resection for stage IA non-small cell lung cancer, it continues to be a point of considerable debate. Improved imaging techniques have introduced a large group of smaller and more indolent tumors ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2016.04.007
更新日期：2016-08-01 00:00:00
abstract：:Stage IVA disease can be de novo disease or more commonly represent recurrent disease. The pleura is the most common site of relapse after thymoma resection. Local pleural disease is usually simply resected. This is usually combined with either induction or adjuvant chemotherapy. The ultimate extended surgery for adva...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2010.08.007
更新日期：2011-02-01 00:00:00
abstract：:Thoracoscopic lobectomy is emerging as the procedure of choice for patients with early stage non-small cell lung cancer, based on advantages in quality of life as well as long-term outcomes. In addition, thoracoscopic lobectomy has been demonstrated to be safe and effective for selected patients with locally advanced ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2008.04.002
更新日期：2008-08-01 00:00:00
abstract：:Surgical treatment of locally advanced or recurrent breast cancer involving the chest wall continues to play a role in the therapeutic armamentarium as part of the multidisciplinary treatment regimen. Significant progress has been made in chest wall resections and reconstructions, thanks to the availability of novel m...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2017.01.009
更新日期：2017-05-01 00:00:00
abstract：:Research on surgically implanted devices not only can raise issues familiar from drug studies, but also can raise special challenges. This article suggests some ways in which device trials can raise distinctive ethical issues. The AbioCor artificial heart trial is used as an example. Although this particular trial sho...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2005.06.009
更新日期：2005-11-01 00:00:00
abstract：:Benign stenosis of trachea results mainly from tracheotomy, ventilation, or trauma. The combination of a defect of the mucosa or the tracheal wall and infection produce secondary scar tissue healing with shrinkage of the tracheal lumen or instability of the tracheal wall. Standard of treatment consists of resection of...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2013.09.001
更新日期：2014-02-01 00:00:00
abstract：:The incorporation of research into a career in thoracic surgery is a complex process. Ideally, the preparation for a career in academic thoracic surgery begins with a research fellowship during training. In the academic setting, a research portfolio might include clinical research, translational research, or basic res...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章
doi：10.1016/j.thorsurg.2011.04.004
更新日期：2011-08-01 00:00:00
abstract：:Anatomic lung segmentectomy is a possible alternative to lobectomy for small (<2 cm) primary lung cancers. Interest in anatomic lung segmentectomy has increased further after the adoption of high-resolution computed tomography and the implementation of lung cancer screening studies, which are increasing the detection ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2014.02.008
更新日期：2014-05-01 00:00:00
abstract：:MDCT using thin collimation and postprocessing techniques, such as multiplanar reformations along and perpendicular to the central axes of the central airways, and volume rendering techniques, such as virtual bronchoscopy and virtual bronchography, has become the imaging modality of choice for the diagnosis of nonneop...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章
doi：10.1016/j.thorsurg.2009.12.005
更新日期：2010-02-01 00:00:00
abstract：:Esophageal cancer requires a multimodality treatment approach, with surgical resection a key component in many cases. When it comes to esophagectomy, several approaches and techniques exist, including transhiatal versus transthoracic and open versus minimally invasive. Each approach has its associated risks and advant...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2020.04.010
更新日期：2020-08-01 00:00:00
abstract：:This article provides an overview of current literature on blunt tracheobronchial injury, and discusses the presentation of tracheobronchial injuries in clinical and radiographic forms. A review of the current data on repair is provided with an outline of surgical management. ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2018.04.008
更新日期：2018-08-01 00:00:00
abstract：:Despite significant improvements in surgical technique and perioperative care, the management of patients requiring chest wall resection and reconstruction is an ongoing challenge for thoracic surgeons. A successful approach includes a thorough assessment of the patient and the lesion, an adequate biopsy to confirm ti...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2010.07.008
更新日期：2010-11-01 00:00:00
abstract：:Despite advances in treatment, long-term outcomes for esophageal cancer remain poor, with overall survival rates of between 15% and 35%. Poor long-term survival reflects locoregionally advanced disease or metastatic disease at presentation. Among patients undergoing surgical resection, 40% to 50% have stage III diseas...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2013.07.007
更新日期：2013-11-01 00:00:00
abstract：:Air leakage after pulmonary resections is considered the most prevalent postoperative problem, and it is often the only morbidity identified. Ideally, treatment begins with prevention; the onset of this complication should be anticipated and recognized during surgery, and intraoperative strategies should be attempted ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2010.03.004
更新日期：2010-08-01 00:00:00
abstract：:Because the esophagus is a tubular muscular structure only partially filled with air and surrounded by major structures (vessels, lungs, and heart), its radiologic evaluation cannot be performed solely by conventional chest radiograph or barium studies. The emergence of newer techniques has had a dramatic effect on th...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章
doi：10.1016/j.thorsurg.2010.12.007
更新日期：2011-05-01 00:00:00
abstract：:Tracheobronchomalacia is an uncommon acquired disorder of the central airways. Common symptoms include dyspnea, constant coughing, inability to raise secretions, and recurrent respiratory infections. Evaluation includes an inspiratory-expiratory chest CT (dynamic CT), an awake functional bronchoscopy, and pulmonary fu...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2018.01.006
更新日期：2018-05-01 00:00:00
