Abstract：
:Research on surgically implanted devices not only can raise issues familiar from drug studies, but also can raise special challenges. This article suggests some ways in which device trials can raise distinctive ethical issues. The AbioCor artificial heart trial is used as an example. Although this particular trial should not be deemed typical of surgically implanted device studies, it can highlight some particularly significant methodologic and ethical features.
journal_name
Thorac Surg Clinjournal_title
Thoracic surgery clinicsauthors
Morreim EHdoi
10.1016/j.thorsurg.2005.06.009keywords:
subject
Has Abstractpub_date
2005-11-01 00:00:00pages
555-63, viiiissue
4eissn
1547-4127issn
1558-5069pii
S1547-4127(05)00087-3journal_volume
15pub_type
杂志文章,评审abstract：:The literature shows that, in the hands of experienced thoracoscopic surgeons, VL is a safe operation that offers patients at least comparable complication and survival rates compared with lobectomy by thoracotomy. VL can be performed safely with proven advantages over conventional thoracotomy for lobectomy: smaller i...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2007.03.019
更新日期：2007-05-01 00:00:00
abstract：:Professional oaths and codes do not establish a firm basis for the obligation to treat all patients and they provide little or no clear guidance about whether patient nonadherence exempts a physician from a longstanding and still prevalent tradition in surgery supports a strong obligation to one's established patients...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2005.06.012
更新日期：2005-11-01 00:00:00
abstract：:Patients express risk aversion toward surgery, particularly if surgery can lead to lifelong debility and loss of independence. When faced with a guarantee of progressive lung cancer and no alternatives for cure, however, patients are willing to take extremely high risks of postoperative complications and surgery-relat...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章
doi：10.1016/S1547-4127(04)00016-7
更新日期：2004-08-01 00:00:00
abstract：:The venous side of the systemic vascular circulation returns the left ventricular cardiac output in a converging fashion to the superior and inferior vena cava and hence to the right atrium. Oxygenated blood is returned to the left atrium. The volumes of these 2 systems are in balance in a normal physiologic state. ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章
doi：10.1016/j.thorsurg.2010.12.010
更新日期：2011-05-01 00:00:00
abstract：:The incorporation of research into a career in thoracic surgery is a complex process. Ideally, the preparation for a career in academic thoracic surgery begins with a research fellowship during training. In the academic setting, a research portfolio might include clinical research, translational research, or basic res...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章
doi：10.1016/j.thorsurg.2011.04.004
更新日期：2011-08-01 00:00:00
abstract：:Development of postpneumonectomy empyema with bronchopleural fistula is a life-threatening condition that requires prompt action. Although measures should be taken to prevent bronchopleural fistula at time of pneumonectomy, many patients experience this complication. Management focuses on drainage of the pleural space...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2018.05.008
更新日期：2018-08-01 00:00:00
abstract：:Esophageal cancer requires a multimodality treatment approach, with surgical resection a key component in many cases. When it comes to esophagectomy, several approaches and techniques exist, including transhiatal versus transthoracic and open versus minimally invasive. Each approach has its associated risks and advant...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2020.04.010
更新日期：2020-08-01 00:00:00
abstract：:Anatomic lung segmentectomy is a possible alternative to lobectomy for small (<2 cm) primary lung cancers. Interest in anatomic lung segmentectomy has increased further after the adoption of high-resolution computed tomography and the implementation of lung cancer screening studies, which are increasing the detection ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2014.02.008
更新日期：2014-05-01 00:00:00
abstract：:Recent studies have shown that patients who are down-staged via neoadjuvant therapy and undergo resection have a significant increased 5-year survival rate (as high as 40%-50%) when compared with patients who have residual N2 disease. The identification of patients who are N2 negative after the completion of their neo...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2008.08.002
更新日期：2008-11-01 00:00:00
abstract：:Video-assisted thoracic surgery (VATS) lobectomy has become a standard approach for early stage 1 lung cancer. However, concerns still remain regarding certain clinical situations, such as potential damage to the heart or bypass grafts when VATS is performed after median sternotomy for cardiac surgery. In this article...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2015.04.004
更新日期：2015-08-01 00:00:00
abstract：:Assessment for thoracic surgery in elderly patients should be based on physiologic rather than chronologic age. Thoracic surgery has been shown to be safe in selected elderly patients, and age should not be a contraindication to a therapy that offers the best chance of cure for patients with early-stage cancer. A targ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2014.07.001
更新日期：2014-11-01 00:00:00
abstract：:Arterial thoracic outlet syndrome is rare and may be associated with a bony anomaly. Patient presentation can range from mild arm discoloration and claudication to severe limb-threatening ischemia. For patients with subclavian artery dilation without secondary complications, thoracic outlet decompression and arterial ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2020.09.006
更新日期：2021-02-01 00:00:00
abstract：:Curing cancer requires the treatment of metastatic disease. Whether this is a patient with advanced disease and clinically apparent metastases, or if the patient with localized disease is at risk for development of dissemination, failure to control metastasis will result in a poor outcome. Here, we have presented a mo...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2005.12.003
更新日期：2006-05-01 00:00:00
abstract：:Endoscopic thoracic sympathectomy (ETS) is an effective treatment of primary hyperhidrosis of the face, upper extremities, and axillae. The major limitation is the side effect of compensatory sweating severe enough that patients request reversal in up to 10% of cases. When ETS is performed by cutting the sympathetic c...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2016.06.006
更新日期：2016-11-01 00:00:00
abstract：:Nanotechnology is an emerging field with potential as an adjunct to cancer therapy, particularly thoracic surgery. Therapy can be delivered to tumors in a more targeted fashion, with less systemic toxicity. Nanoparticles may aid in diagnosis, preoperative characterization, and intraoperative localization of thoracic t...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2015.12.009
更新日期：2016-05-01 00:00:00
abstract：:The aim of this study is to assess in bronchial carcinoid tumors, the prognostic factors in relation to the histology that would determine their most appropriate therapy. The histologic aggressiveness is a determining factor in tumor size and nodal involvement in these tumors. The knowledge of the histologic limits of...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2014.05.003
更新日期：2014-08-01 00:00:00
abstract：:This article focuses on new materials available to thoracic surgeons for the reconstruction of chest wall defects. Each surgeon is called to select the best reconstructive strategy based on the disease for which the resection is needed, the possible extension to adjacent structures, the availability of professional co...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2010.06.005
更新日期：2010-11-01 00:00:00
abstract：:Despite the potential differences in patient characteristics, study designs, and types of instruments used, this review of the literature showed several common findings. Important improvements in QOL are reported after lung transplantation. These improvements were observed when cross-sectional comparisons were made ac...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/S1547-4127(04)00025-8
更新日期：2004-08-01 00:00:00
abstract：:Bassed on the authors' review of the unusual variants of PPS and the body of published experience, a revision of the current classification scheme for PPS into a more comprehensive form is justified as follows: (1) by the nature of obstruction; and (2) by the time of onset. This classification encompasses early and la...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2006.05.001
更新日期：2006-08-01 00:00:00
abstract：:Pulmonary metastasis occurs in as many as 88% and 80% of stage IV patients with sarcoma and germ cell tumors, respectively. Pulmonary metastatectomy may be the only means of rendering a patient disease free. Sublobar resection (wedge or segmentectomy), lobectomy, and pneumonectomy achieve complete resection. Bilateral...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2015.09.007
更新日期：2016-02-01 00:00:00
abstract：:The few long-term survivors of MPM have been cured with radical surgical extirpation often followed by radiation therapy and adjuvant chemotherapy. The combination of pemetrexed and cisplatin recently was shown to improve survival over treatment with cisplatin alone. Given the size and robustness of that trial, the co...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2004.06.010
更新日期：2004-11-01 00:00:00
abstract：:Postoperative pain following thoracic surgery presents a significant challenge, and multiple factors complicate recovery and pain management for this population. Considerable comorbidities often exist in thoracic surgical patients, further limiting therapeutic options. Elements of nociceptive and neuropathic pain may ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2015.07.005
更新日期：2015-11-01 00:00:00
abstract：:Surgery for tuberculosis is becoming more relevant today. This article discusses the main indications, contraindications, features of operations, and perioperative period. This information is useful for practicing surgeons and specialists in the treatment of pulmonary tuberculosis. ...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2018.09.003
更新日期：2019-02-01 00:00:00
abstract：:In recent years, the subxiphoid approach has been used to avoid intercostal nerve damage in the field of thoracic surgery. A subxiphoid single-port thymectomy does not require sternotomy; it is associated with lesser pain because there is no intercostal nerve damage; and it provides excellent cosmetic outcomes. Furthe...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2017.06.006
更新日期：2017-11-01 00:00:00
abstract：:Detection of clinically occult lung neoplasms may represent an opportunity for early curative intervention. Fluorescent bronchoscopy is a sensitive technique for detecting early endobronchial tumors that may be combined with CT scanning as part of a comprehensive lung cancer screening program. Identification and longi...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/S1547-4127(04)00041-6
更新日期：2004-02-01 00:00:00
abstract：:Thoracoscopy has afforded a huge advance for upper thoracic sympathetic procedures compared with prior open procedures. Different clinical syndromes of hyperhidrosis exist and require different forms of treatment. The classic severe palmoplantar pattern of hyperhidrosis will not respond effectively in the long term to...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2008.01.005
更新日期：2008-05-01 00:00:00
abstract：:Hydatid disease is caused by the parasite Echinococcus granulosus. The liver and the lungs are common sites. When a cystic lesion is seen on CT scan, diagnosis is made based on the patient having lived in an endemic area. Serologic tests are used for differential diagnosis. Medical treatment is centered on albendazole...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2012.04.004
更新日期：2012-08-01 00:00:00
abstract：:A thorough knowledge of thoracic anatomy is of fundamental importance to the thoracic surgeon. Surface anatomy is an often-neglected component of traditional topographic anatomic teaching, but a proper understanding of the relationship of surface features to deeper structures is invaluable in the clinical assessment o...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2006.12.002
更新日期：2007-11-01 00:00:00
abstract：:Gastroesophageal reflux disease (GERD) is a well-defined disease characterized by symptoms or complications caused by an abnormal amount of GER, which is a retrograde movement of gastric contents into the esophagus. Laryngopharyngeal reflux (LPR) is a subset of GERD and given its own identity, because the main symptom...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2011.08.001
更新日期：2011-11-01 00:00:00
abstract：:In summary, from the different alternatives to conventional hospitalization developed in the last decades, outpatient surgery has been the one with the greatest growth. However, only few studies have been reported on thoracic surgery and there is still great potential for an increase in outpatient thoracic surgery. Th...
journal_title：Thoracic surgery clinics
pub_type： 杂志文章,评审
doi：10.1016/j.thorsurg.2008.04.003
更新日期：2008-08-01 00:00:00
