Abstract:
:MPM is an uncommon disease with limited treatment options. Early diagnosis, a standardized staging system, early referral to centers experienced in MPM, and efforts to develop collaborative multicenter trials are essential to improving treatment for patients with MPM. Efforts to manage this malignancy, which is projected to peak in the twenty-first century, constitute an important international health concern, particularly because the use of asbestos, despite successful regulatory efforts in many parts of the world, continues unabated in others.
journal_name
Thorac Surg Clinjournal_title
Thoracic surgery clinicsauthors
Kukreja J,Jaklitsch MT,Wiener DC,Sugarbaker DJ,Burgers S,Baas Pdoi
10.1016/j.thorsurg.2004.06.009keywords:
subject
Has Abstractpub_date
2004-11-01 00:00:00pages
435-45issue
4eissn
1547-4127issn
1558-5069pii
S1547-4127(04)00124-0journal_volume
14pub_type
杂志文章,评审abstract::The incorporation of research into a career in thoracic surgery is a complex process. Ideally, the preparation for a career in academic thoracic surgery begins with a research fellowship during training. In the academic setting, a research portfolio might include clinical research, translational research, or basic res...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章
doi:10.1016/j.thorsurg.2011.04.004
更新日期:2011-08-01 00:00:00
abstract::Early stage non-small cell lung cancer is a potentially curable manifestation of a disease that is typically associated with a grim prognosis. Therapies directed at early stage disease can be challenging to deliver because patients tend to be elderly with multiple comorbidities. Surgery, the standard of care, has been...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2013.05.009
更新日期:2013-08-01 00:00:00
abstract::In recent years, the subxiphoid approach has been used to avoid intercostal nerve damage in the field of thoracic surgery. A subxiphoid single-port thymectomy does not require sternotomy; it is associated with lesser pain because there is no intercostal nerve damage; and it provides excellent cosmetic outcomes. Furthe...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2017.06.006
更新日期:2017-11-01 00:00:00
abstract::Because the esophagus is a tubular muscular structure only partially filled with air and surrounded by major structures (vessels, lungs, and heart), its radiologic evaluation cannot be performed solely by conventional chest radiograph or barium studies. The emergence of newer techniques has had a dramatic effect on th...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章
doi:10.1016/j.thorsurg.2010.12.007
更新日期:2011-05-01 00:00:00
abstract::Vertebral body resection for locally advanced lung cancer can be performed with acceptable morbidity and mortality rates, and with improved long-term survival, when combined with chemotherapy and radiation. A consensus has not been reached on either the optimal extent of vertebral resection or the optimal treatment re...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/S1547-4127(04)00009-X
更新日期:2004-05-01 00:00:00
abstract::Despite the potential differences in patient characteristics, study designs, and types of instruments used, this review of the literature showed several common findings. Important improvements in QOL are reported after lung transplantation. These improvements were observed when cross-sectional comparisons were made ac...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/S1547-4127(04)00025-8
更新日期:2004-08-01 00:00:00
abstract::The search for clinically applicable biologic markers or tumor signatures sufficiently powered as prognosticators of tumor behaviors or responses to therapeutic interventions has significantly advanced in scope and sophistication in the last 10 years. The TNM system, examining of tumor tissues to identify histopatholo...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2006.07.004
更新日期:2006-11-01 00:00:00
abstract::Nerve injuries can cause substantial morbidity after thoracic surgical procedures. These injuries are preventable, provided that the surgeon has a thorough understanding of the anatomy and follows important surgical principles. When nerve injuries occur, it is important to recognize the options available in the immedi...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2015.07.012
更新日期:2015-11-01 00:00:00
abstract::Benign stenosis of trachea results mainly from tracheotomy, ventilation, or trauma. The combination of a defect of the mucosa or the tracheal wall and infection produce secondary scar tissue healing with shrinkage of the tracheal lumen or instability of the tracheal wall. Standard of treatment consists of resection of...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2013.09.001
更新日期:2014-02-01 00:00:00
abstract::This article has reviewed radiation treatment of thoracic malignancies in elderly patients. In general the literature suggests that thoracic irradiation is equally efficacious in elderly patients as in younger patients and is associated with increased but acceptable toxicity. Technical advances are allowing a further ...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2009.06.003
更新日期:2009-08-01 00:00:00
abstract::MDCT using thin collimation and postprocessing techniques, such as multiplanar reformations along and perpendicular to the central axes of the central airways, and volume rendering techniques, such as virtual bronchoscopy and virtual bronchography, has become the imaging modality of choice for the diagnosis of nonneop...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章
doi:10.1016/j.thorsurg.2009.12.005
更新日期:2010-02-01 00:00:00
abstract::The benefits derived from comprehensive PR, when applied to patients who have lung cancer, should have significant impact on both survival and health status. Because PR is known to improve exercise capacity, it is reasonable to expect that this treatment modality may provide more patients with a potential cure. In add...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2007.10.003
更新日期:2008-02-01 00:00:00
abstract::Bassed on the authors' review of the unusual variants of PPS and the body of published experience, a revision of the current classification scheme for PPS into a more comprehensive form is justified as follows: (1) by the nature of obstruction; and (2) by the time of onset. This classification encompasses early and la...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2006.05.001
更新日期:2006-08-01 00:00:00
abstract::Staging of malignant pleural mesothelioma has been challenging because of a paucity of cases and poor survival. At least 5 staging systems were proposed before 1990 until the first consensus system was published in 1995. This system used tumor, node, metastasis designations and borrowed heavily from parenchymal lung c...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2020.07.001
更新日期:2020-11-01 00:00:00
abstract::Postoperative pain following thoracic surgery presents a significant challenge, and multiple factors complicate recovery and pain management for this population. Considerable comorbidities often exist in thoracic surgical patients, further limiting therapeutic options. Elements of nociceptive and neuropathic pain may ...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2015.07.005
更新日期:2015-11-01 00:00:00
abstract::Research on surgically implanted devices not only can raise issues familiar from drug studies, but also can raise special challenges. This article suggests some ways in which device trials can raise distinctive ethical issues. The AbioCor artificial heart trial is used as an example. Although this particular trial sho...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2005.06.009
更新日期:2005-11-01 00:00:00
abstract::As we enter the 21st century, thoracic surgeons can look back with pride and gratitude to their predecessors who placed a high premium on clinical practice and certification. Thoracic surgery, however, is dynamic, not static. So, too, should be thoracic surgery recertification. In recent years, considerable effort has...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2007.07.001
更新日期:2007-08-01 00:00:00
abstract::Detection of clinically occult lung neoplasms may represent an opportunity for early curative intervention. Fluorescent bronchoscopy is a sensitive technique for detecting early endobronchial tumors that may be combined with CT scanning as part of a comprehensive lung cancer screening program. Identification and longi...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/S1547-4127(04)00041-6
更新日期:2004-02-01 00:00:00
abstract::Despite advances in treatment, long-term outcomes for esophageal cancer remain poor, with overall survival rates of between 15% and 35%. Poor long-term survival reflects locoregionally advanced disease or metastatic disease at presentation. Among patients undergoing surgical resection, 40% to 50% have stage III diseas...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2013.07.007
更新日期:2013-11-01 00:00:00
abstract::Despite a prospective randomized trial that reported decreased locoregional recurrence for the intentional use of sublobar resection for stage IA non-small cell lung cancer, it continues to be a point of considerable debate. Improved imaging techniques have introduced a large group of smaller and more indolent tumors ...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2016.04.007
更新日期:2016-08-01 00:00:00
abstract::Concerns regarding the sequelae of neoadjuvant chemotherapy or chemoradiotherapy on the pleural space and tissue planes had previously deterred the application of video-assisted thoracoscopic (VATS) lobectomy for patients who underwent neoadjuvant therapy. As experience with VATS has increased, however, its applicatio...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2014.07.013
更新日期:2014-11-01 00:00:00
abstract::European studies have contributed significantly to the understanding of lung cancer screening. Smoking within screening, quality of life, nodule management, minimally invasive treatments, cancer prevention programs, and risk models have been extensively investigated by European groups. Mortality data from European scr...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2014.12.002
更新日期:2015-05-01 00:00:00
abstract::The advent of immune checkpoint blockade has revolutionized the management of advanced non-small cell lung cancer (NSCLC). Impressive results in the metastatic setting have prompted substantial interest in the application of these agents in earlier-stage disease. Applications of checkpoint blockade in the adjuvant set...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2020.01.001
更新日期:2020-05-01 00:00:00
abstract::Curing cancer requires the treatment of metastatic disease. Whether this is a patient with advanced disease and clinically apparent metastases, or if the patient with localized disease is at risk for development of dissemination, failure to control metastasis will result in a poor outcome. Here, we have presented a mo...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2005.12.003
更新日期:2006-05-01 00:00:00
abstract::Development of postpneumonectomy empyema with bronchopleural fistula is a life-threatening condition that requires prompt action. Although measures should be taken to prevent bronchopleural fistula at time of pneumonectomy, many patients experience this complication. Management focuses on drainage of the pleural space...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2018.05.008
更新日期:2018-08-01 00:00:00
abstract::Practically, hiatal hernias are divided into sliding hiatal hernias (type I) and PEH (types II, III, or IV). Patients with PEH are usually symptomatic with GERD or obstructive symptoms, such as dysphagia. Rarely, patients present with acute symptoms of hernia incarceration, such as severe epigastric pain and retching....
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2009.08.006
更新日期:2009-11-01 00:00:00
abstract::Stage IVA disease can be de novo disease or more commonly represent recurrent disease. The pleura is the most common site of relapse after thymoma resection. Local pleural disease is usually simply resected. This is usually combined with either induction or adjuvant chemotherapy. The ultimate extended surgery for adva...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2010.08.007
更新日期:2011-02-01 00:00:00
abstract::The current convention is for bilateral one-stage lung volume reduction surgery. Unilateral surgery results in a symptomatic improvement in most patients. A staged approach to the second lung may reduce the risk of surgery and lead to a slower decline in physiologic improvement. The timing of the second operation can ...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2009.02.001
更新日期:2009-05-01 00:00:00
abstract::Endoscopic thoracic sympathectomy (ETS) is an effective treatment of primary hyperhidrosis of the face, upper extremities, and axillae. The major limitation is the side effect of compensatory sweating severe enough that patients request reversal in up to 10% of cases. When ETS is performed by cutting the sympathetic c...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2016.06.006
更新日期:2016-11-01 00:00:00
abstract::Pediatric mediastinal tumors and cysts are rare disorders that share many similarities with adults, yet which have important differences unique to the child. Posterior mediastinal tumors are relatively more common in children than in adults and are also more likely to be malignant in children. CT imaging facilitates t...
journal_title:Thoracic surgery clinics
pub_type: 杂志文章,评审
doi:10.1016/j.thorsurg.2008.09.014
更新日期:2009-02-01 00:00:00