Carbon and arsenic metabolism in Thiomonas strains: differences revealed diverse adaptation processes.

abstract：BACKGROUND:Hepatitis C virus (HCV) core protein and nonstructural protein 4B (NS4B) are potentially oncogenic. Aberrant activation of the Wnt/β-catenin signaling pathway is closely associated with hepatocarcinogenesis. We investigated the effects of HCV type 1b core protein and NS4B on Wnt/β-catenin signaling in variou...

journal_title：BMC microbiology

authors： Jiang XH,Xie YT,Cai YP,Ren J,Ma T

更新日期：2017-05-25 00:00:00

abstract：BACKGROUND:Streptococcus pseudopneumoniae, is a novel member of the genus Streptococcus, falling close to related members like S. pneumoniae, S. mitis, and S. oralis. Its recent appearance has shed light on streptococcal infections, which has been unclear till recently. In this study, the transcriptome of S. pseudopneu...

journal_title：BMC microbiology

authors： Park HK,Myung SC,Kim W

更新日期：2012-07-06 00:00:00

abstract：BACKGROUND:Streptococcus pneumoniae is a common respiratory pathogen and a major causative agent of respiratory infections, including otitis media (OM). Pneumococcal biofilms have been demonstrated on biopsies of the middle ear mucosa in children receiving tympanostomy tubes, supporting the hypothesis that chronic OM m...

journal_title：BMC microbiology

authors： Hall-Stoodley L,Nistico L,Sambanthamoorthy K,Dice B,Nguyen D,Mershon WJ,Johnson C,Hu FZ,Stoodley P,Ehrlich GD,Post JC

更新日期：2008-10-08 00:00:00

abstract：BACKGROUND:Fluconazole (FLC), a triazole antifungal drug, is widely used for the maintenance therapy of cryptococcal meningoencephalitis, the most common opportunistic infection in AIDS patients. In this study, we examined changes in the gene expression profile of the C. neoformans reference strain H99 (serotype A) fol...

journal_title：BMC microbiology

authors： Florio AR,Ferrari S,De Carolis E,Torelli R,Fadda G,Sanguinetti M,Sanglard D,Posteraro B

更新日期：2011-05-11 00:00:00

abstract：BACKGROUND:The lung of patients with cystic fibrosis (CF) is particularly sensitive to Pseudomonas aeruginosa. This bacterium plays an important role in the poor outcome of CF patients. During the disease progress, first acquisition of P. aeruginosa is the key-step in the management of CF patients. Quantitative PCR (qP...

journal_title：BMC microbiology

authors： Le Gall F,Le Berre R,Rosec S,Hardy J,Gouriou S,Boisramé-Gastrin S,Vallet S,Rault G,Payan C,Héry-Arnaud G

更新日期：2013-06-21 00:00:00

abstract：BACKGROUND:Staphylococcus aureus is an opportunistic commensal bacterium that mostly colonizes the skin and soft tissues. The pathogenicity of S. aureus is due to both its ability to resist antibiotics, and the production of toxins. Here, we characterize a group of genes responsible for toxin production and antibiotic ...

journal_title：BMC microbiology

authors： Sina H,Ahoyo TA,Moussaoui W,Keller D,Bankolé HS,Barogui Y,Stienstra Y,Kotchoni SO,Prévost G,Baba-Moussa L

更新日期：2013-08-08 00:00:00

abstract：BACKGROUND:Footrot and interdigital dermatitis are endemic infectious diseases in all sheep farming regions, impairing welfare and production. The development of efficacious vaccines against the primary causative pathogen has been hampered by the extensive antigenic diversity of Dichelobacter nodosus. Understanding the...

journal_title：BMC microbiology

authors： Davies PL,Blanchard AM,Staley CE,Bollard NJ,Coffey TJ,Tötemeyer S

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Epidemiology of celiac disease (CD) is increasing. CD mainly presents in early childhood with small intestinal villous atrophy and signs of malabsorption. Compared to healthy individuals, CD patients seemed to be characterized by higher numbers of Gram-negative bacteria and lower numbers Gram-positive bacter...

journal_title：BMC microbiology

authors： Di Cagno R,De Angelis M,De Pasquale I,Ndagijimana M,Vernocchi P,Ricciuti P,Gagliardi F,Laghi L,Crecchio C,Guerzoni ME,Gobbetti M,Francavilla R

更新日期：2011-10-04 00:00:00

abstract：BACKGROUND:Although the most widely accepted mechanism of action for polymyxins is related to bacterial lysis via disruption, we hypothesized that this antimicrobial drug class could have other effects on Pseudomonas aeruginosa planktonic and sessile cells. Little is known regarding oxidative burst and zeta potential (...

journal_title：BMC microbiology

authors： Lima MR,Ferreira GF,Nunes Neto WR,Monteiro JM,Santos ÁRC,Tavares PB,Denadai ÂML,Bomfim MRQ,Dos Santos VL,Marques SG,de Souza Monteiro A

更新日期：2019-05-29 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is known as a leading cause of morbidity and mortality. Investigation of the MRSA's virulence and resistance mechanisms is a continuing concern toward controlling such burdens through using high throughput whole Genome Sequencing (WGS) and molecular diagnost...

journal_title：BMC microbiology

authors： Ali MS,Isa NM,Abedelrhman FM,Alyas TB,Mohammed SE,Ahmed AE,Ahmed ZSA,Lau NS,Garbi MI,Amirul AA,Seed AO,Omer RA,Mohamed SB

更新日期：2019-06-11 00:00:00

abstract：BACKGROUND:Several conventional methods, including fungal culture and periodic acid-Schiff (PAS) reagent staining, have been used to diagnose oral candidiasis. The aim of this study was to evaluate the efficacy of a novel method, fungal fluorescent staining, in relation to conventional protocols in the diagnosis of ora...

journal_title：BMC microbiology

authors： Yao Y,Shi L,Zhang C,Sun H,Wu L

更新日期：2019-05-14 00:00:00

abstract：BACKGROUND:Salmonella enterica serovar Typhimurium (Typhimurium) is an important pathogen that infects a broad range of hosts. In humans, Typhimurium causes a gastroenteritis characterized by vomiting, diarrhea, and abdominal pains. Typhimurium infection occurs mainly through the ingestion of contaminated food includin...

journal_title：BMC microbiology

authors： Dieye Y,Ameiss K,Mellata M,Curtiss R 3rd

更新日期：2009-01-06 00:00:00

abstract：BACKGROUND:Bacteria employ multiple mechanisms to control gene expression and react to their constantly changing environment. Bacterial growth in rich laboratory medium is a dynamic process in which bacteria utilize nutrients from simple to complex and change physical properties of the medium, as pH, during the process...

journal_title：BMC microbiology

authors： Sitkiewicz I,Musser JM

更新日期：2009-02-10 00:00:00

abstract：BACKGROUND:The KdpD/KdpE two-component system of Escherichia coli regulates expression of the kdpFABC operon encoding the high affinity K+ transport system KdpFABC. The input domain of KdpD comprises a domain that belongs to the family of universal stress proteins (Usp). It has been previously demonstrated that UspC bi...

journal_title：BMC microbiology

authors： Heermann R,Lippert ML,Jung K

更新日期：2009-07-09 00:00:00

abstract：BACKGROUND:Recent studies suggest that the reported protective effects of statins (HMG-CoA reductase inhibitors) against community-acquired pneumonia (CAP) and sepsis in humans may be due to confounders and a healthy user-effect. To directly test whether statins are protective against Streptococcus pneumoniae, the lead...

journal_title：BMC microbiology

authors： Boyd AR,Hinojosa CA,Rodriguez PJ,Orihuela CJ

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:Trichomonas vaginalis is a human urogenital pathogen responsible for trichomonosis, the number-one, non-viral sexually transmitted disease (STD) worldwide, while T. tenax is a commensal of the human oral cavity, found particularly in patients with poor oral hygiene and advanced periodontal disease. The exten...

journal_title：BMC microbiology

authors： Kucknoor AS,Mundodi V,Alderete J

更新日期：2009-03-18 00:00:00

abstract：BACKGROUND:Avian pathogenic Escherichia coli (APEC) and uropathogenic E. coli (UPEC) are the two main subsets of extraintestinal pathogenic E. coli (ExPEC). Both types have multiple iron acquisition systems, including heme and siderophores. Although iron transport systems involved in the pathogenesis of APEC or UPEC ha...

journal_title：BMC microbiology

authors： Gao Q,Wang X,Xu H,Xu Y,Ling J,Zhang D,Gao S,Liu X

更新日期：2012-07-20 00:00:00

abstract：BACKGROUND:The influence of the membrane-bound AAA+ protease FtsH on membrane and cytoplasmic proteins of Corynebacterium glutamicum was investigated in this study. For the analysis of the membrane fraction, anion exchange chromatography was combined with SDS-PAGE, while the cytoplasmic protein fraction was studied by ...

journal_title：BMC microbiology

authors： Lüdke A,Krämer R,Burkovski A,Schluesener D,Poetsch A

更新日期：2007-01-25 00:00:00

abstract：BACKGROUND:Modifiable lifestyle factors (e.g. dietary intake and physical activity) are important contributors to weight gain during college. The purpose of this study was to evaluate whether associations exist between body mass index, physical activity, screen time, dietary consumption (fat, protein, carbohydrates, an...

journal_title：BMC microbiology

authors： Whisner CM,Maldonado J,Dente B,Krajmalnik-Brown R,Bruening M

更新日期：2018-12-12 00:00:00

abstract：BACKGROUND:Microbiome and metagenomic studies have given rise to a new understanding of microbial colonization of various human tissues and their ability to impact our health. One human microbiome growing in notoriety, the vaginal microbiome, stands out given its importance for women's health, and is peculiar in terms ...

journal_title：BMC microbiology

authors： Brandt K,Barrangou R

更新日期：2020-11-10 00:00:00

abstract：BACKGROUND:Sigma factors are one of the components of RNA polymerase holoenzymes, and an essential factor of transcription initiation in bacteria. Corynebacterium glutamicum possesses seven genes coding for sigma factors, most of which have been studied to some detail; however, the role of SigD in transcriptional regul...

journal_title：BMC microbiology

authors： Taniguchi H,Busche T,Patschkowski T,Niehaus K,Pátek M,Kalinowski J,Wendisch VF

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:Chlamydia trachomatis, an obligate intracellular human pathogen, is the most prevalent bacterial sexually transmitted infection worldwide and a leading cause of preventable blindness. HtrA is a virulence and stress response periplasmic serine protease and molecular chaperone found in many bacteria. Recombina...

journal_title：BMC microbiology

authors： Huston WM,Theodoropoulos C,Mathews SA,Timms P

更新日期：2008-11-06 00:00:00

abstract：BACKGROUND:In the present work, we describe a group of anomalous dose-response (DR) profiles and develop a dynamic model that is able to explain them. Responses were obtained from conventional assays of three antimicrobial agents (nisin, pediocin and phenol) against two microorganisms (Carnobacterium piscicola and Leuc...

journal_title：BMC microbiology

authors： Murado MA,Vázquez JA

更新日期：2010-08-19 00:00:00

abstract：BACKGROUND:Salmonella enterica is a facultative intracellular pathogen that replicates within a membrane-bound compartment termed Salmonella containing vacuole (SCV). The biogenesis of SCV requires Salmonella type III protein secretion/translocation system and their effector proteins which are translocated into host ce...

journal_title：BMC microbiology

authors： Wang X,Li D,Qu D,Zhou D

更新日期：2010-08-26 00:00:00

abstract：BACKGROUND:Bartonella henselae is a Gram-negative bacterium transmitted to humans by a scratch from cat in the presence of ectoparasites. Humans infected with B. henselae can result in various clinical diseases including local lymphadenopathy and more serious systemic disease such as persistent bacteremia and endocardi...

journal_title：BMC microbiology

authors： Zheng X,Ma X,Li T,Shi W,Zhang Y

更新日期：2020-04-10 00:00:00

abstract：BACKGROUND:Papua New Guinea (PNG) is a high tuberculosis (TB) burden country of the WHO Western Pacific Region, but so far research on drug resistance (DR) and genotypes of Mycobacterium tuberculosis (M. tuberculosis) was only conducted in few provinces in the country. The aim of the present study was to obtain baselin...

journal_title：BMC microbiology

authors： Ley SD,Harino P,Vanuga K,Kamus R,Carter R,Coulter C,Pandey S,Feldmann J,Ballif M,Siba PM,Phuanukoonnon S,Gagneux S,Beck HP

更新日期：2014-12-05 00:00:00

abstract：BACKGROUND:Recent scientific developments have shed more light on the importance of the host-microbe interaction, particularly in the gut. However, the mechanistic study of the host-microbe interplay is complicated by the intrinsic limitations in reaching the different areas of the gastrointestinal tract (GIT) in vivo....

journal_title：BMC microbiology

authors： Marzorati M,Vanhoecke B,De Ryck T,Sadaghian Sadabad M,Pinheiro I,Possemiers S,Van den Abbeele P,Derycke L,Bracke M,Pieters J,Hennebel T,Harmsen HJ,Verstraete W,Van de Wiele T

更新日期：2014-05-22 00:00:00

abstract：BACKGROUND:"Candidatus Phytoplasma aurantifolia", is the causative agent of witches' broom disease in Mexican lime trees (Citrus aurantifolia L.), and is responsible for major losses of Mexican lime trees in Southern Iran and Oman. The pathogen is strictly biotrophic, and thus is completely dependent on living host cel...

journal_title：BMC microbiology

authors： Zamharir MG,Mardi M,Alavi SM,Hasanzadeh N,Nekouei MK,Zamanizadeh HR,Alizadeh A,Salekdeh GH

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Salmonella enteritidis is suggested to translocate in the small intestine. In vivo it induces gene expression changes in the ileal mucosa and Peyer's patches. Stimulation of Salmonella translocation by dietary prebiotics fermented in colon suggests involvement of the colon as well. However, effects of Salmon...

journal_title：BMC microbiology

authors： Rodenburg W,Keijer J,Kramer E,Roosing S,Vink C,Katan MB,van der Meer R,Bovee-Oudenhoven IM

更新日期：2007-09-12 00:00:00

abstract：BACKGROUND:A common assumption of microorganisms is that laboratory stocks will remain genetically and phenotypically constant over time, and across laboratories. It is becoming increasingly clear, however, that mutations can ruin strain integrity and drive the divergence or "domestication" of stocks. Since its discove...

journal_title：BMC microbiology

authors： Carroll SM,Xue KS,Marx CJ

更新日期：2014-01-02 00:00:00