Abstract:
STUDY DESIGN:Retrospective single center analysis. OBJECTIVE:The purpose of our study is to quantify the development of a postoperative radiculitis in our minimally invasive transforaminal lumbar interbody fusion patient population. SUMMARY OF BACKGROUND DATA:The application of recombinant human Bone Morphogenetic Protein-2 (BMP) in spinal surgery has allowed for greater success in spinal fusions. This has led to the FDA approving its use in anterior lumbar interbody fusion. However, its well-recognized benefits have generated its "off-label" use in the cervical, thoracic, and lumbar spine. Despite its benefits, the adverse effects of its inflammatory properties are just starting to get recognized. Some clear adverse reactions have been documented in the literature in the cervical spine. However, we feel that these inflammatory properties may be present in the lumbar spine as well. METHODS:We performed a retrospective chart review of 43 patients who had undergone a minimally invasive transforaminal lumbar interbody fusions. Thirty-five of these patients had BMP and 8 patients did not have BMP. We documented whether there was a preoperative radiculopathy present and whether a radiculopathy was present postoperative. We reviewed radiographic postoperative imaging to establish a structural cause for any radiculopathy. If new or increasing radicular symptoms were present, we attempted to assess the duration of these symptoms. RESULTS:Our analysis, showed that 0 of the 8 patients of the non-BMP group had new radicular symptoms that were not attributed to structural causes. In the BMP group, 4 of the 35 patients (11.4%) had new radicular symptoms without structural etiology. CONCLUSION:Our analysis suggest that patients undergoing minimally invasive transforaminal lumbar interbody fusions procedures have a higher incidence of developing new radicular symptoms that could be attributed to BMP.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Mindea SA,Shih P,Song JKdoi
10.1097/BRS.0b013e3181a396a1subject
Has Abstractpub_date
2009-06-15 00:00:00pages
1480-4; discussion 1485issue
14eissn
0362-2436issn
1528-1159pii
00007632-200906150-00010journal_volume
34pub_type
杂志文章相关文献
SPINE文献大全abstract:STUDY DESIGN:Retrospective database analysis. OBJECTIVE:To determine C2 fracture patterns associated with vertebral artery injury (VAI) as assessed by computed tomography angiography. SUMMARY OF BACKGROUND DATA:The incidence of C2 fracture hospitalizations has increased significantly in the last decade. The vertebral...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000000893
更新日期:2015-06-15 00:00:00
abstract::The authors attempted to investigate the effect of vibration on the physiologic behavior of the intervertebral disc from rheologic and biological responses. Using fresh disc-cartilaginous end plate complexes of porcine coccygeal vertebrae, the frequency characteristics of dynamic compressive elastic modulus and dissip...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199203001-00002
更新日期:1992-03-01 00:00:00
abstract:STUDY DESIGN:Retrospective Cohort OBJECTIVE.: Investigate and establish minimum clinically important differences (MCID) for PHQ-9 among patients undergoing minimally invasive transforaminal lumbar interbody fusion (MIS TLIF). SUMMARY OF BACKGROUND:Spine surgery is linked to postoperative improvements in anxiety, depre...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000003853
更新日期:2020-12-07 00:00:00
abstract:STUDY DESIGN:Forty-four consecutive thoracic idiopathic adolescent curves surgically treated between 1995 and 1999 at one institution were analyzed. All were thoracic curves; there were no lumbar curves, double major curves, or triple major curves. OBJECTIVES:To study the clinical and radiographic results for these 44...
journal_title:Spine
pub_type: 临床试验,杂志文章
doi:10.1097/00007632-200209150-00018
更新日期:2002-09-15 00:00:00
abstract:STUDY DESIGN:Survey. OBJECTIVE:The aim of this study was to objectify the burden of adolescent idiopathic scoliosis (AIS) to better advocate for scoliosis care in the future. SUMMARY OF BACKGROUND DATA:AIS is a common spinal deformity that can affect individuals on many levels. Patients with big curves usually seek m...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001708
更新日期:2017-01-15 00:00:00
abstract:STUDY DESIGN:A questionnaire survey. OBJECTIVE:To assess the preferred surgical technique, the optimal timing of surgery, and the expectations of different surgical techniques of neurosurgeons in the Netherlands, regarding patients with cervical disc herniation (CDH). SUMMARY OF BACKGROUND DATA:To treat CDH, multiple...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001743
更新日期:2017-03-01 00:00:00
abstract:STUDY DESIGN:Retrospective case series. OBJECTIVE:To report the effect of repeated growing rod (GR) lengthenings on the sagittal and pelvic profile in patients with early-onset scoliosis. SUMMARY OF BACKGROUND DATA:Posterior distraction-based GRs have gained popularity as a technique for the surgical management of ea...
journal_title:Spine
pub_type: 杂志文章,多中心研究
doi:10.1097/BRS.0000000000000565
更新日期:2014-10-15 00:00:00
abstract:OBJECTIVE:To summarize the clinical manifestations and treatment of acquired hemophilia A in a patient with lumbar disc herniation. SUMMARY OF BACKGROUND DATA:Acquired hemophilia A is a rare but potentially life-threatening hemorrhagic disorder. It is caused by the development of autoantibodies directed against coagul...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0b013e31819740d6
更新日期:2009-04-15 00:00:00
abstract:STUDY DESIGN:Herniated lumbar disc specimens were cocultured with peripheral blood mononuclear cells, and cells isolated from extruded disc were cultured to study the production of matrix metalloproteinases. OBJECTIVE:To investigate the role of peripheral blood mononuclear cells infiltrating extruded discs and disc-de...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200107150-00004
更新日期:2001-07-15 00:00:00
abstract:STUDY DESIGN:A total of 12 human cervical spines were tested in vitro in a biomechanical nondestructive set-up to compare the primary stability of different posterior cervical instrumentations after a bilevel corpectomy. OBJECTIVE:To evaluate the primary 3-dimensional stability with special focus on the impact of cerv...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181e6bc59
更新日期:2010-10-15 00:00:00
abstract:STUDY DESIGN:A retrospective study of patients undergoing palliative surgery for metastatic spinal tumors. OBJECTIVE:To investigate short-term functional recovery and duration of improvement after palliative surgery, to correlate these outcomes with the revised Tokuhashi score, and to examine the relationship between ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181878733
更新日期:2008-10-01 00:00:00
abstract::Electrically evoked compound action potentials were used to quantify the neurophysiologic abnormalities caused by application of chymopapain into the lumbar spinal canal in rats. A branch of the sciatic nerve was stimulated with voltage impulses of constant amplitude (40 V) and duration (0.1 msec) at the right externa...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198901000-00013
更新日期:1989-01-01 00:00:00
abstract:STUDY DESIGN:Retrospective analysis of lumbosacral radiculography using 3-dimensional (3D) magnetic resonance (MR) rendering in patients with extraforaminal disc herniation. OBJECTIVE:To investigate the significance of lumbosacral radiculography as depicted by 3D MR rendering in the diagnosis of symptomatic extraforam...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3182374465
更新日期:2012-05-01 00:00:00
abstract:STUDY DESIGN:Prospective randomized controlled animal model. OBJECTIVE:The purpose of this study is to determine whether the readministration of human recombinant bone morphogenetic protein-2 (rhBMP-2) induces an immune response and inhibits successful fusion in repeat posterolateral spinal surgery. SUMMARY OF BACKGR...
journal_title:Spine
pub_type: 杂志文章,随机对照试验
doi:10.1097/BRS.0b013e3181cdd396
更新日期:2011-02-01 00:00:00
abstract:STUDY DESIGN:In vivo animal study. OBJECTIVES:To describe a new porcine disc degeneration model, and to analyze disc remodeling and degeneration after nucleotomy with special view to the different nucleus pulposus (NP) cell types. SUMMARY OF BACKGROUND DATA:Thus far, predominantly smaller animals were used for disc d...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181b723c9
更新日期:2009-12-01 00:00:00
abstract:STUDY DESIGN:A population-based, prospective cohort study. OBJECTIVE:To identify demographic, job-related, psychosocial, and clinical factors associated with the use of magnetic resonance imaging (MRI) within 6 weeks from injury (early MRI) among workers' compensation claimants with acute occupational low back pain (L...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31823a03cc
更新日期:2012-09-01 00:00:00
abstract:STUDY DESIGN:A retrospective study. OBJECTIVE:To compare the mid-term outcomes of hybrid surgery (HS) and anterior cervical discectomy and fusion (ACDF) for the treatment of contiguous two-segment cervical degenerative disc diseases. SUMMARY OF BACKGROUND DATA:HS has become one of the most controversial subjects in s...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000002639
更新日期:2018-10-15 00:00:00
abstract:STUDY DESIGN:We performed a retrospective study of 668 consecutive patients with congenital spine deformities. OBJECTIVES:To determine the prevalence of Goldenhar conditions in patients with congenital spine deformities, and describe the types of vertebral abnormalities and their treatment. SUMMARY OF BACKGROUND DATA...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000219876.45640.2a
更新日期:2006-06-01 00:00:00
abstract:STUDY DESIGN:A biomechanical study was designed to assess relative rigidity provided by anterior, posterior, or combined cervical fixation using cadaveric cervical spine models for flexion-distraction injury and burst fracture. OBJECTIVES:To compare the construct stability provided by anterior plating with locked fixa...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200101010-00005
更新日期:2001-01-01 00:00:00
abstract:STUDY DESIGN:In vitro and in vivo study. OBJECTIVE:To evaluate the role of recombinant human bone morphogenetic protein-2 (rhBMP2) on breast cancer cell (MDA-MB-231 cells) growth. SUMMARY OF BACKGROUND DATA:Bone morphogenetic proteins (BMPs) are expressed in a variety of human carcinoma cell lines and are known to pr...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31827db4c6
更新日期:2013-02-01 00:00:00
abstract:STUDY DESIGN:Case report. OBJECTIVE:To report a case of an acute intracranial subdural hematoma that formed due to cerebrospinal fluid (CSF) leak following lumbar surgery. SUMMARY OF BACKGROUND DATA:Intracranial hypotension may occur when CSF is removed from the subarachnoid space. Intracranial subdural hematoma form...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000192208.66360.29
更新日期:2005-12-15 00:00:00
abstract:STUDY DESIGN:Prospective cohort study. OBJECTIVE:To analyze the serum and drain concentrations of antibiotics administered by two different routes and compare the results. SUMMARY OF BACKGROUND DATA:Systemic antibiotics are expected to reach the surgical site and maintain adequate concentrations of the drug to preven...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000003238
更新日期:2020-02-15 00:00:00
abstract:STUDY DESIGN:A case is reported in which a 45-year-old man developed cauda equina syndrome caused by enlargement of an L4-L5 juxtafacet cyst diagnosed 4 months earlier. OBJECTIVES:To highlight the short interval that can elapse between the discovery of a juxtafacet cyst and its remarkable progression. SUMMARY OF BACK...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200206010-00022
更新日期:2002-06-01 00:00:00
abstract:STUDY DESIGN:Isolated tubercular involvement of craniovertebral junction in a human immunodeficiency virus-positive patient causing paraplegia and sudden death with radiologic features is presented. OBJECTIVES:Isolated involvement of craniovertebral junction by tuberculosis causing quadriparesis is a rare entity. The ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.BRS.0000083257.63544.A9
更新日期:2003-08-01 00:00:00
abstract:STUDY DESIGN:A baseline study of the general population and the health care providers in 3 Norwegian counties. OBJECTIVE:To investigate if beliefs about low back pain (LBP) are related to personal experiences and profession sought for care. SUMMARY OF BACKGROUND DATA:Myths about LBP that are abandoned by health profe...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000171909.81632.fe
更新日期:2005-08-01 00:00:00
abstract:STUDY DESIGN:Cerebrospinal fluid (CSF) from dogs with intervertebral disc herniation (IVDH) were analyzed using a specific antibody against cartilage oligomeric matrix protein (COMP). Immunolocalization and genetic expression of COMP were also examined in the spinal cords of mouse, rat, and dog. OBJECTIVE:To investiga...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181b61f14
更新日期:2010-01-01 00:00:00
abstract::Fifteen cervical spines from cadavers were used to compare the rotational and translational stability of the Brooks fusion, a fusion construct using Halifax interlaminar clamps, and the Gallie fusion. The Brooks and Halifax clamp constructs exhibited significantly greater rotational and translational stiffness than th...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199302000-00001
更新日期:1993-02-01 00:00:00
abstract:STUDY DESIGN:A case report. OBJECTIVE:To describe a case of traumatic lumbosacral spondyloptosis and present a literature review. SUMMARY OF BACKGROUND DATA:Traumatic spondyloptosis is a very rare injury caused by high-energy trauma. Eight cases of traumatic spondyloptosis of L5-S1 have been reported, including only ...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0b013e318268c08a
更新日期:2012-10-15 00:00:00
abstract::The purpose of this study was to determine the incidence and severity of degenerative changes seen on lateral roentgenograms in 200 asymptomatic men and women in five age groups with an age range of 20-65 years and to determine the normal values of cervical lordosis and spinal canal sagittal diameters and their relati...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198607000-00003
更新日期:1986-07-01 00:00:00
abstract::Computed tomography represents one of the most remarkable short-term technical advances ever seen in medicine. Its recent extension to scanning of the lumbar spine promises to become its most significant extra-cranial application. The accusation has been made that CT scanning represents an expensive diagnostic modalit...
journal_title:Spine
pub_type: 历史文章,杂志文章
doi:10.1097/00007632-197907000-00003
更新日期:1979-07-01 00:00:00