Abstract:
STUDY DESIGN:A retrospective study of patients undergoing palliative surgery for metastatic spinal tumors. OBJECTIVE:To investigate short-term functional recovery and duration of improvement after palliative surgery, to correlate these outcomes with the revised Tokuhashi score, and to examine the relationship between function and neurologic deterioration. SUMMARY OF BACKGROUND DATA:The revised Tokuhashi score is a scoring system used to predict life expectancy for patients with metastatic spinal tumors. The relationship between the revised Tokuhashi score and physical functional improvement after palliative surgery has not been examined previously. METHODS:The clinical charts of 86 patients were reviewed. The Eastern Cooperative Oncology Group Performance Status (ECOG-PS) was used to assess physical function. Each score was documented before surgery and at every month after surgery. The duration of ECOG-PS improvement, defined as the period between surgery and deterioration to the preoperative ECOG-PS grade, was correlated with the revised Tokuhashi score. RESULTS:The ECOG-PS grade improved in 44 (51.1%) patients at 1 month postoperative. When ECOG-PS improvement was found after surgery, it persisted above the preoperative level for an average of 9.3 months. At 1 month postoperative, patients scoring 0 to 8 on the total revised Tokuhashi score had significantly lower ECOG-PS improvement (26 of 55 patients) when compared to patients with higher scores (18 of 27 patients, P < 0.05). In 44 patients with ECOG-PS improvement, the existence of major internal organ metastases significantly shortened the duration of improvement (P < 0.05). CONCLUSION:Palliative surgery benefited half of the patients with metastatic spinal tumor, with a greater probability of benefit found in persons with a higher total revised Tokuhashi score (score 9-15) and/or primary cancers with longer survival times.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Yamashita T,Aota Y,Kushida K,Murayama H,Hiruma T,Takeyama M,Iwamura Y,Saito Tdoi
10.1097/BRS.0b013e3181878733subject
Has Abstractpub_date
2008-10-01 00:00:00pages
2341-6issue
21eissn
0362-2436issn
1528-1159pii
00007632-200810010-00015journal_volume
33pub_type
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