Effect of spinal construct stiffness on short segment fusion mass incorporation.


STUDY DESIGN:Three segment (L3-L5) pedicle screw constructs were implanted in caprine spines, and the resulting ankylosis evaluated mechanically and compared 12 weeks after surgery. OBJECTIVES:To determine if a construct of maximal stiffness could impair the biologic process of spinal arthrodesis by "stress-shielding." SUMMARY OF BACKGROUND DATA:Fusion mass stiffness is believed to be enhanced by increasing construct stiffness, although previous studies have used semirigid, nonconstrained constructs, which lose stiffness through cyclical loading. Device-related osteoporosis, reported to occur with stiff, constrained implants, may be more related to the presence of fusion induced by the implants rather than the implants themselves. METHODS:In 15 goats, L3-L5 segments were instrumented with pedicle screws, and four different diameters of rods (3.2 cm, 4.8 cm, 6.4 mm, and no rods) were implanted as longitudinal connections to vary the stiffness of the constructs. After 12 weeks, animals were killed and the segments were tested to determine their stiffness. RESULTS:In lateral bending, spines "fused" with rods (any size) were significantly stiffer (P = 0.03) than nonrodded spines. There was a trend toward stiffer segments with larger rods (4.8 cm or 6.4 mm) compared with 3.2 mm or no rods. There was a highly significant (P < 0.0001) increase in stiffness of all operated (rodded or nonrodded) segments compared with unoperated controls. CONCLUSIONS:The enhancement of segmental stiffness by stiffer constructs was confirmed, suggesting a beneficial effect on spinal arthrodesis by increasing stiffness. Stress shielding could not be shown.


Spine (Phila Pa 1976)




Johnston CE 2nd,Welch RD,Baker KJ,Ashman RB




Has Abstract


1995-11-15 00:00:00














  • Upper extremity palsy following cervical decompression surgery results from a transient spinal cord lesion.

    abstract:STUDY DESIGN:Retrospective analysis. OBJECTIVE:To test the hypothesis that spinal cord lesions cause postoperative upper extremity palsy. SUMMARY OF BACKGROUND DATA:Postoperative paresis, so-called C5 palsy, of the upper extremities is a common complication of cervical surgery. Although there are several hypotheses r...


    pub_type: 杂志文章,多中心研究


    authors: Hasegawa K,Homma T,Chiba Y

    更新日期:2007-03-15 00:00:00

  • Strategies of medical intervention in the management of acute spinal cord injury.

    abstract:STUDY DESIGN:: Literature review. OBJECTIVE:: The purpose of this paper is to review clinical treatment strategies and future developments in the treatment of acute spinal cord injury. SUMMARY OF BACKGROUND DATA:: The treatment of acute spinal cord injury continues to be supportive. The search for specialized pharmac...


    pub_type: 杂志文章,评审


    authors: Hurlbert RJ

    更新日期:2006-05-15 00:00:00

  • Lymphocyte Count at 4 Days Postoperatively: A Reliable Screening Marker for Surgical Site Infection After Posterior Lumbar Decompression Surgery.

    abstract:STUDY DESIGN:Case-control study. OBJECTIVE:To identify laboratory markers for surgical site infection (SSI) in posterior lumbar decompression surgery, which are not affected by operative factors, and to determine the diagnostic cutoffs of these markers. SUMMARY OF BACKGROUND DATA:Numerous laboratory markers are used ...


    pub_type: 杂志文章,多中心研究


    authors: Iwata E,Shigematsu H,Yamamoto Y,Tanaka M,Okuda A,Morimoto Y,Masuda K,Nakajima H,Koizumi M,Tanaka Y

    更新日期:2018-09-15 00:00:00

  • Measurements of surgeons' exposure to ionizing radiation dose during intraoperative use of C-arm fluoroscopy.

    abstract:STUDY DESIGN:Measurement of radiation dose from C-arm fluoroscopy during a simulated intraoperative use in spine surgery. OBJECTIVE.: To investigate scatter radiation doses to specific organs of surgeons during intraoperative use of C-arm fluoroscopy in spine surgery and to provide practical intraoperative guidelines. ...


    pub_type: 杂志文章


    authors: Lee K,Lee KM,Park MS,Lee B,Kwon DG,Chung CY

    更新日期:2012-06-15 00:00:00

  • Respiratory dysfunction in patients with chronic-onset cervical myelopathy.

    abstract:STUDY DESIGN:A retrospective study. OBJECTIVE To clarify the characteristics of respiratory dysfunction associated with chronic-onset cervical myelopathy. SUMMARY OF BACKGROUND DATA:In acute cervical cord injury, respiratory dysfunction, especially vital capacity (VC), is impaired, which causes respiratory complicatio...


    pub_type: 杂志文章


    authors: Ishibe T,Takahashi S

    更新日期:2002-10-15 00:00:00

  • Augmentation of rabbit posterolateral spondylodesis using a novel demineralized bone matrix-hyaluronan putty.

    abstract:STUDY DESIGN:Posterolateral spinal fusion with allogeneic demineralized bone graft-hyaluronan putty in addition to autogenous iliac crest bone graft in a rabbit model. OBJECTIVES:To determine the potential efficacy of demineralized bone graft-hyaluronan putty as a bone graft enhancer. SUMMARY OF BACKGROUND DATA:Autog...


    pub_type: 杂志文章


    authors: Yee AJ,Bae HW,Friess D,Robbin M,Johnstone B,Yoo JU

    更新日期:2003-11-01 00:00:00

  • Spinal chronic subdural hematoma in association with anticoagulant therapy: a case report and literature review.

    abstract:STUDY DESIGN:A case of spinal chronic subdural hematoma (SCSDH) in association with anticoagulant therapy was treated surgically. OBJECTIVE:To clarify the etiopathogenesis, clinical presentation, and surgical outcomes of SCSDH. SUMMARY OF BACKGROUND DATA:Intracranial chronic subdural hematoma is a well-recognized com...


    pub_type: 杂志文章,评审


    authors: Jimbo H,Asamoto S,Mitsuyama T,Hatayama K,Iwasaki Y,Fukui Y

    更新日期:2006-03-15 00:00:00

  • Anterior surgical management of single-level cervical disc disease: a cost-effectiveness analysis.

    abstract:STUDY DESIGN:Cost-effectiveness analysis with decision analysis and meta-analysis. OBJECTIVE:To determine the relative cost-effectiveness of anterior cervical discectomy with fusion (with autograft, allograft, or spacers), anterior cervical discectomy without fusion (ACD), and cervical disc replacement (CDR) for the t...


    pub_type: 杂志文章,meta分析


    authors: Lewis DJ,Attiah MA,Malhotra NR,Burnett MG,Stein SC

    更新日期:2014-12-01 00:00:00

  • Quantitative dynamic measures of physical exposure predict low back functional impairment.

    abstract:STUDY DESIGN:Prospective field study of work exposure and changes in back function. OBJECTIVE:Quantify dynamic physical exposures in the workplace and their association with decreases in kinematic back function (indicative of low back pain [LBP]). SUMMARY OF BACKGROUND DATA:Previous epidemiologic studies of work have...


    pub_type: 杂志文章


    authors: Marras WS,Lavender SA,Ferguson SA,Splittstoesser RE,Yang G

    更新日期:2010-04-15 00:00:00

  • A novel method of cervical pedicle screw placement from C3 to C5 and its clinical applications.

    abstract:STUDY DESIGN:Applied anatomical study and clinical application. OBJECTIVE:To design and optimize the method of cervical pedicle screw placement for cervical vertebrae C3-C5, and to test it in clinical applications. SUMMARY OF BACKGROUND DATA:Most of the anatomical studies on cervical pedicle screw placement previousl...


    pub_type: 杂志文章


    authors: Liu J,Li Y,Wu Y,Zhu Q

    更新日期:2013-04-15 00:00:00

  • Primary Ewing sarcoma of the spine mimicking a psoas abscess secondary to spinal infection.

    abstract:STUDY DESIGN:A case of primary Ewing sarcoma of the lumbar spine is presented. OBJECTIVE:To present and review a rare case of primary Ewing sarcoma of the lumbar spine that required differentiation from spinal infection. SUMMARY OF BACKGROUND DATA:Primary Ewing sarcoma originating from the spinal column is very rare....


    pub_type: 杂志文章


    authors: Akeda K,Kasai Y,Kawakita E,Seto M,Kono T,Uchida A

    更新日期:2009-04-20 00:00:00

  • Prevalence and risk factors associated with low back pain among health care providers in a Kuwait hospital.

    abstract:STUDY DESIGN:A cross-sectional survey among health professionals working in a Kuwait hospital. OBJECTIVE:To investigate the prevalence and factors associated with low back pain (LBP). SUMMARY OF BACKGROUND DATA:The literature suggests that health professionals are exposed to occupational risk factors that predispose ...


    pub_type: 杂志文章


    authors: Landry MD,Raman SR,Sulway C,Golightly YM,Hamdan E

    更新日期:2008-03-01 00:00:00

  • Neck pain in Hong Kong: a telephone survey on prevalence, consequences, and risk groups.

    abstract:STUDY DESIGN:A cross-sectional telephone survey was conducted using a two-stage randomization process. OBJECTIVES:The objectives of this paper were to investigate the prevalence of neck pain and their consequences and risk groups in the Hong Kong population. SUMMARY OF BACKGROUND DATA:There has been a lack of recent ...


    pub_type: 杂志文章


    authors: Chiu TT,Leung AS

    更新日期:2006-07-15 00:00:00

  • Validation of a noninvasive technique to precisely measure in vivo three-dimensional cervical spine movement.

    abstract:STUDY DESIGN:In vivo validation during functional loading. OBJECTIVE:To determine the accuracy and repeatability of a model-based tracking technique that combines subject-specific computed tomographic (CT) models and high-speed biplane x-ray images to measure three-dimensional (3D) in vivo cervical spine motion. SUMM...


    pub_type: 杂志文章


    authors: Anderst WJ,Baillargeon E,Donaldson WF 3rd,Lee JY,Kang JD

    更新日期:2011-03-15 00:00:00

  • Prophylactic stabilization of vertebral body metastasis at risk of imminent fracture using balloon kyphoplasty.

    abstract:STUDY DESIGN:Case report. OBJECTIVE:Presentation of the previously unreported technique of balloon kyphoplasty being used to prophylactically stabilize a vertebral body metastasis at risk of imminent fracture. SUMMARY OF BACKGROUND DATA:Many patients with spinal metastases are not suitable for a total en bloc resecti...


    pub_type: 杂志文章


    authors: Langdon J,Bernard J,Molloy S

    更新日期:2009-06-01 00:00:00

  • Outcomes of workers' compensation claimants with low back pain undergoing intradiscal electrothermal therapy.

    abstract:STUDY DESIGN:Case series. OBJECTIVE:To describe the outcomes of workers' compensation (WC) claimants who have had a lumbar intradiscal electrothermal therapy (IDET) procedure. SUMMARY OF BACKGROUND DATA:IDET was developed as a less invasive treatment alternative to fusion after failure of conservative treatment for d...


    pub_type: 杂志文章


    authors: Webster BS,Verma S,Pransky GS

    更新日期:2004-02-15 00:00:00

  • Intraoperative three dimensional correction during in situ contouring surgery by using a numerical model.

    abstract:STUDY DESIGN:A numerical study was conducted by simulating in situ contouring (ISC) surgery. OBJECTIVE:To quantify intraoperative correction during ISC surgery. SUMMARY OF BACKGROUND DATA:Surgical techniques correcting scoliosis, like the ISC one, lead to a complex 3-dimensional correction of the spine. Using motion ...


    pub_type: 杂志文章


    authors: Lafon Y,Steib JP,Skalli W

    更新日期:2010-02-15 00:00:00

  • Lumbar laminectomy for the resection of synovial cysts and coexisting lumbar spinal stenosis or degenerative spondylolisthesis: an outcome study.

    abstract:STUDY DESIGN:Surgeon- and patient-based (SF-36) outcome measures were used to assess the results of decompressive laminectomies for the excision of synovial cysts with coexistent lumbar spinal stenosis (45 patients) or for synovial cysts with coexistent lumbar stenosis and degenerative spondylolisthesis (35 patients). ...


    pub_type: 杂志文章


    authors: Epstein NE

    更新日期:2004-05-01 00:00:00

  • Lumbar spine fusion for chronic low back pain due to degenerative disc disease: a systematic review.

    abstract:STUDY DESIGN:Systematic literature review. OBJECTIVE:To categorize published evidence systematically for lumbar fusion for chronic low back pain (LBP) in order to provide an updated and comprehensive analysis of the clinical outcomes. SUMMARY OF BACKGROUND DATA:Despite a large number of publications of outcomes of sp...


    pub_type: 杂志文章,评审


    authors: Phillips FM,Slosar PJ,Youssef JA,Andersson G,Papatheofanis F

    更新日期:2013-04-01 00:00:00

  • Using segmental renal artery as recipient artery for spinal reconstructive surgery.

    abstract:STUDY DESIGN:Report of the use of one segmental artery from the left renal artery as inflow source for reconstructing a spine with recalcitrant osteomyelitis. OBJECTIVE:To describe one difficult case of spinal osteomyelitis and our reconstruction procedure. SUMMARY OF BACKGROUND DATA:The use of a vascularized fibular...


    pub_type: 杂志文章


    authors: Yen YH,Hsieh TS,Hou SM,Wu SJ,Chen SC,Pu CM

    更新日期:2010-12-01 00:00:00

  • Comparing the clinical and radiological outcomes of pedicular transvertebral screw fixation of the lumbosacral spine in spondylolisthesis versus unilateral transforaminal lumbar interbody fusion (TLIF) with posterior fixation using anterior cages.

    abstract:STUDY DESIGN:This study retrospectively compares the clinical and radiologic outcomes of unilateral transforaminal lumbar interbody fusion (TLIF) with those of transvertebral screw fixation of the lumbosacral spine in high-grade spondylolisthesis. OBJECTIVE:To examine the outcome and perioperative complications of uni...


    pub_type: 杂志文章


    authors: Rodriguez-Olaverri JC,Zimick NC,Merola A,Vicente J,Rodriguez J,Tabuenca A,Loste A,Suñen E,Burgos J,Hevia E,Piza-Vallespir G

    更新日期:2008-08-15 00:00:00

  • Basic fibroblast growth factor immunoreactivity in blood vessels and cells of disc herniations.

    abstract:STUDY DESIGN:Basic fibroblast growth factor immunoreactivity was studied in disc herniation tissue. OBJECTIVES:The first objective was to analyze in which tissue components, if any, fibroblast growth factor is expressed in the disc herniation. The second objective was to compare such expression with that in fresh cada...


    pub_type: 杂志文章


    authors: Tolonen J,Grönblad M,Virri J,Seitsalo S,Rytömaa T,Karaharju E

    更新日期:1995-02-01 00:00:00

  • Collagenolytic enzyme systems in human intervertebral disc: their control, mechanism, and their possible role in the initiation of biomechanical failure.

    abstract::Changes in the macromolecular matrix of the intervertebral disc may predispose to biomechanical failure of the disc. Such changes would involve extracellular enzymes capable of altering the collagen and proteoglycan of the disc matrix. In this study, extracts from homogenates of both annuli fibrosi and nuclei pulposi ...


    pub_type: 杂志文章


    authors: Sedowofia KA,Tomlinson IW,Weiss JB,Hilton RC,Jayson MI

    更新日期:1982-05-01 00:00:00

  • Thoracic and lumbar fractures associated with femoral shaft fractures in the multiple trauma patient. Occult presentations and implications for femoral fracture stabilization.

    abstract::Two-hundred-and-one patients with femoral shaft fractures were identified in a 5 year period at three institutions. Seven patients (3.5%) were found to have associated thoracic or lumbar fractures of various types. All resulted from high-velocity trauma. Four (57%) of these patients had thoracic or lumbar fractures th...


    pub_type: 杂志文章


    authors: Rupp RE,Ebraheim NA,Chrissos MG,Jackson WT

    更新日期:1994-03-01 00:00:00

  • Spinal manipulation for low back pain. An updated systematic review of randomized clinical trials.

    abstract:STUDY DESIGN:Systematic review of randomized clinical trials. OBJECTIVES:To assess the efficacy of spinal manipulation for patients with low back pain. SUMMARY OF BACKGROUND DATA:The management of low back pain remains controversial. Spinal manipulation is a widely used treatment option for low back pain. Recently is...


    pub_type: 杂志文章,评审


    authors: Koes BW,Assendelft WJ,van der Heijden GJ,Bouter LM

    更新日期:1996-12-15 00:00:00

  • Disparities in rates of spine surgery for degenerative spine disease between HIV-infected and uninfected veterans.

    abstract:STUDY DESIGN:Retrospective analysis of nationwide Veterans Health Administration clinical and administrative data. OBJECTIVE:Examine the association between HIV infection and the rate of spine surgery for degenerative spine disease. SUMMARY OF BACKGROUND DATA:Combination antiretroviral therapy has prolonged survival ...


    pub_type: 杂志文章


    authors: King JT Jr,Gordon AJ,Perkal MF,Crystal S,Rosenthal RA,Rodriguez-Barradas MC,Butt AA,Gibert CL,Rimland D,Simberkoff MS,Justice AC

    更新日期:2012-04-01 00:00:00

  • Intra-observer reproducibility and interobserver reliability of the radiographic parameters in the Spinal Deformity Study Group's AIS Radiographic Measurement Manual.

    abstract:STUDY DESIGN:Retrospective cross-sectional assessment of the reproducibility and reliability of radiographic parameters. OBJECTIVE:To measure the intra-examiner and interexaminer reproducibility and reliability of salient radiographic features. SUMMARY OF BACKGROUND DATA:The management and treatment of adolescent idi...


    pub_type: 杂志文章


    authors: Dang NR,Moreau MJ,Hill DL,Mahood JK,Raso J

    更新日期:2005-05-01 00:00:00

  • Mesenchymal Stem Cell Homing Into Intervertebral Discs Enhances the Tie2-positive Progenitor Cell Population, Prevents Cell Death, and Induces a Proliferative Response.

    abstract:STUDY DESIGN:Experimental study with human mesenchymal stem cells (MSCs) and intervertebral disc (IVD) tissue samples. OBJECTIVE:This study aimed to characterize the effect of MSC homing on the Tie2-positive IVD progenitor cell population, IVD cell survival, and proliferation. SUMMARY OF BACKGROUND DATA:Homing of hum...


    pub_type: 杂志文章


    authors: Wangler S,Peroglio M,Menzel U,Benneker LM,Haglund L,Sakai D,Alini M,Grad S

    更新日期:2019-12-01 00:00:00

  • Spine update. Impaired cognitive functioning after whiplash injury of the cervical spine.

    abstract::To enhance the awareness of physicians treating whiplash patients, findings from previous research regarding cognitive functioning of these patients are discussed and recommendations for assessment provided. Cognitive disturbances (i.e., deficient attentional functioning and impairment of memory) are frequent complain...


    pub_type: 杂志文章,评审


    authors: Radanov BP,Dvorak J

    更新日期:1996-02-01 00:00:00

  • Measurement techniques for lower cervical spine injuries: consensus statement of the Spine Trauma Study Group.

    abstract:STUDY DESIGN:Literature review. OBJECTIVES:It was the purpose of the Spine Trauma Study Group to compile a collection of clinically useful imaging methods used in lower cervical spine trauma and to describe in detail how these measurements should be made. SUMMARY OF BACKGROUND DATA:Injury detection, description, and ...


    pub_type: 共识发展会议,杂志文章,评审


    authors: Bono CM,Vaccaro AR,Fehlings M,Fisher C,Dvorak M,Ludwig S,Harrop J

    更新日期:2006-03-01 00:00:00