External Validation of the Adult Spinal Deformity (ASD) Frailty Index (ASD-FI) in the Scoli-RISK-1 Patient Database.

Abstract:

STUDY DESIGN:Analysis of a prospective multicenter database. OBJECTIVE:To assess the ability of the recently created Adult Spinal Deformity (ASD) Frailty Index (ASD-FI) to predict odds of major complications and length of hospital stay for patients who had more severe preoperative deformity and underwent more invasive ASD surgery compared with patients in the database used to create the index. SUMMARY OF BACKGROUND DATA:Accurate preoperative estimates of risk are necessary given the high complication rates currently associated with ASD surgery. METHODS:Patients were enrolled by participating institutions in Europe, Asia, and North America from 2009 to 2011. ASD-FI scores were used to classify 267 patients as not frail (NF) (<0.3), frail (0.3-0. 5), or severely frail (SF) (>0.5). Multivariable logistic regression, adjusted for preoperative and surgical covariates such as operative time and blood loss, was performed to determine the relationship between ASD-FI category and incidence of major complications, overall incidence of complications, and length of hospital stay. RESULTS:The mean ASD-FI score was 0.3 (range, 0-0.7). We categorized 105 patients as NF, 103 as frail, and 59 as SF. The adjusted odds of developing a major complication were higher for SF patients (odds ratio = 4.4; 95% CI 2.0, 9.9) compared with NF patients. After adjusting for covariates, length of hospital stay for SF patients increased by 19% (95% CI 1.4%, 39%) compared with NF patients. The odds of developing a major complication or having increased length of stay were similar between frail and NF patients. CONCLUSION:Greater patient frailty, as measured by the ASD-FI, is associated with a longer hospital stay and greater risk of major complications among patients who have severe preoperative deformity and undergo invasive surgical procedures. LEVEL OF EVIDENCE:2.

journal_name

Spine (Phila Pa 1976)

journal_title

Spine

authors

Miller EK,Lenke LG,Neuman BJ,Sciubba DM,Kebaish KM,Smith JS,Qiu Y,Dahl BT,Pellisé F,Matsuyama Y,Carreon LY,Fehlings MG,Cheung KM,Lewis S,Dekutoski MB,Schwab FJ,Boachie-Adjei O,Mehdian H,Bess S,Shaffrey CI,Ames CP

doi

10.1097/BRS.0000000000002717

subject

Has Abstract

pub_date

2018-10-15 00:00:00

pages

1426-1431

issue

20

eissn

0362-2436

issn

1528-1159

pii

00007632-201810150-00014

journal_volume

43

pub_type

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