Abstract:
STUDY DESIGN:Case report. OBJECTIVES:To report primary angiosarcoma of the T8 vertebra, which was successfully managed with en bloc spondylectomy and postoperative chemotherapy. SUMMARY OF BACKGROUND DATA:To the best of our knowledge, the present case is the first documented example of successful treatment of angiosarcoma of the spine. METHODS:Angiosarcoma of the eighth thoracic vertebra was diagnosed in a 48-year-old man with impending neurologic deficit. Imaging findings revealed a nonspecific high-grade lesion. A total spondylectomy of T8 by en bloc resection was performed. The defect of the vertebral body was reconstructed with a apatite-wollastonite glass ceramic prosthesis; moreover, the T6-T10 vertebrae were instrumented by the pedicle screw, hook and rod system. The histologic diagnosis of the excised specimen was high-grade angiosarcoma. Postoperative chemotherapy was implemented to prevent local recurrence and distant metastasis. RESULTS:No sign of local recurrence or metastasis was evident 5 years after surgery. CONCLUSION:This case is the first documented example of successful treatment of angiosarcoma of the thoracic spine. Radiologic findings were nonspecific; consequently, correct diagnosis was established by pathologic examination. Immediate, aggressive operative treatment and postoperative adjuvant chemotherapy afforded a satisfactory outcome.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Kawashima H,Ishikawa S,Fukase M,Ogose A,Hotta Tkeywords:
subject
Has Abstractpub_date
2004-07-01 00:00:00pages
E280-3issue
13eissn
0362-2436issn
1528-1159pii
00007632-200407010-00026journal_volume
29pub_type
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