Genetic determination of the effect of post-translational modification on the innate immune response to the 19 kDa lipoprotein of Mycobacterium tuberculosis.

abstract：BACKGROUND:The kinetoplast DNA (kDNA) of trypanosomatids consists of an unusual arrangement of circular molecules catenated into a single network. The diameter of the isolated kDNA network is similar to that of the entire cell. However, within the kinetoplast matrix, the kDNA is highly condensed. Studies in Crithidia f...

journal_title：BMC microbiology

authors： Cavalcanti DP,Shimada MK,Probst CM,Souto-Padrón TC,de Souza W,Goldenberg S,Fragoso SP,Motta MC

更新日期：2009-06-04 00:00:00

abstract：BACKGROUND:The genus Phytophthora includes a group of agriculturally important pathogens and they are commonly regarded as water molds. They produce motile zoospores that can move via water currents and on their own locomotion in aquatic environments. However, zoosporic response to dissolved oxygen, an important water ...

journal_title：BMC microbiology

authors： Kong P,Hong C

更新日期：2014-05-13 00:00:00

abstract：BACKGROUND:The evolution of mycoplasmas from a common ancestor with Firmicutes has been characterized not only by genome down-sizing but also by horizontal gene transfer between mycoplasma species sharing a common host. The mechanisms of these gene transfers remain unclear because our knowledge of the mycoplasma mobile...

journal_title：BMC microbiology

authors： Breton M,Tardy F,Dordet-Frisoni E,Sagne E,Mick V,Renaudin J,Sirand-Pugnet P,Citti C,Blanchard A

更新日期：2012-11-12 00:00:00

abstract：BACKGROUND:The species Pectobacterium carotovorum includes a diverse subspecies of bacteria that cause disease on a wide variety of plants. In Morocco, approximately 95% of the P. carotovorum isolates from potato plants with tuber soft rot are P. carotovorum subsp. carotovorum. However, identification of this pathogen ...

journal_title：BMC microbiology

authors： Kettani-Halabi M,Terta M,Amdan M,El Fahime el M,Bouteau F,Ennaji MM

更新日期：2013-07-29 00:00:00

abstract：BACKGROUND:Microorganisms are a large and diverse form of life. Many of them live in association with large multicellular organisms, developing symbiotic relations with the host and some have even evolved to form obligate endosymbiosis. All Carpenter ants (genus Camponotus) studied hitherto harbour primary endosymbioti...

journal_title：BMC microbiology

authors： de Souza DJ,Bézier A,Depoix D,Drezen JM,Lenoir A

更新日期：2009-02-06 00:00:00

abstract：BACKGROUND:Lactic acid bacteria (LAB) has been considered a beneficial bacterial group, found as part of the microbiota of diverse hosts, including humans and various animals. However, the mechanisms of how hosts and LAB interact are still poorly understood. Previous work demonstrates that 13 species of Lactobacillus a...

journal_title：BMC microbiology

authors： Butler È,Alsterfjord M,Olofsson TC,Karlsson C,Malmström J,Vásquez A

更新日期：2013-10-22 00:00:00

abstract：BACKGROUND:The ColRS two-component system has been shown to contribute to the membrane functionality and stress tolerance of Pseudomonas putida as well as to the virulence of Pseudomonas aeruginosa and plant pathogenic Xanthomonas species. However, the conditions activating the ColRS pathway and the signal(s) sensed by...

journal_title：BMC microbiology

authors： Ainsaar K,Mumm K,Ilves H,Hõrak R

更新日期：2014-06-20 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) biofilm producers represent an important etiological agent of many chronic human infections. Antibiotics and host immune responses are largely ineffective against bacteria within biofilms. Alternative actions and novel antimicrobials should be considered. In...

journal_title：BMC microbiology

authors： Dakheel KH,Rahim RA,Neela VK,Al-Obaidi JR,Hun TG,Isa MNM,Yusoff K

更新日期：2019-05-28 00:00:00

abstract：BACKGROUND:Despite the high prevalence of genotype 1b hepatitis C virus (HCV) among patients, a cell culture system that permits entire viral life cycle of genotype 1b isolates is limited. To develop a cell-cultured hepatitis C virus (HCVcc) of genotype 1b, the proper combination of HCV genomic variants and host cells ...

journal_title：BMC microbiology

authors： Mori KI,Matsumoto A,Maki N,Ichikawa Y,Tanaka E,Yagi S

更新日期：2016-09-27 00:00:00

abstract：BACKGROUND:A disrupted cell cycle progression of hepatocytes was reported in chronic hepatitis C virus (HCV) infection, which can contribute significantly in the associated pathogenesis. The present study aimed to further elaborate these disruptions by evaluating the expression of key cell cycle and apoptotic proteins ...

journal_title：BMC microbiology

authors： Sarfraz S,Hamid S,Siddiqui A,Hussain S,Pervez S,Alexander G

更新日期：2008-08-05 00:00:00

abstract：BACKGROUND:The environment is the likely source of many pathogenic mycobacterial species but detection of mycobacteria by bacteriological tools is generally difficult and time-consuming. Consequently, several molecular targets based on the sequences of housekeeping genes, non-functional RNA and structural ribosomal RNA...

journal_title：BMC microbiology

authors： Radomski N,Roguet A,Lucas FS,Veyrier FJ,Cambau E,Accrombessi H,Moilleron R,Behr MA,Moulin L

更新日期：2013-12-03 00:00:00

abstract：BACKGROUND:Over the last years oleaginous yeasts have been studied for several energetic, oleochemical, medical and pharmaceutical purposes. However, only a small number of yeasts are known and have been deeply exploited. The search for new isolates with high oleaginous capacity becomes imperative, as well as the use o...

journal_title：BMC microbiology

authors： Miranda C,Bettencourt S,Pozdniakova T,Pereira J,Sampaio P,Franco-Duarte R,Pais C

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:Enterococcus is ubiquitous in nature and is a commensal of both the bovine and human gastrointestinal (GI) tract. It is also associated with clinical infections in humans. Subtherapeutic administration of antibiotics to cattle selects for antibiotic resistant enterococci in the bovine GI tract. Antibiotic re...

journal_title：BMC microbiology

authors： Beukers AG,Zaheer R,Goji N,Amoako KK,Chaves AV,Ward MP,McAllister TA

更新日期：2017-03-08 00:00:00

abstract：BACKGROUND:Enteropathogenic Escherichia coli (EPEC) are classified into typical and atypical strains based on the presence of the E. coli adherence factor (EAF) plasmid. The EAF plasmid contains the bfp (bundle-forming pilus) operon and the perABC (plasmid encoded regulator) gene cluster. A 1-kb cryptic region of EAF p...

journal_title：BMC microbiology

authors： Teixeira NB,Rojas TC,da Silveira WD,Matheus-Guimarães C,Silva NP,Scaletsky IC

更新日期：2015-10-05 00:00:00

abstract：BACKGROUND:Salmonella enteritidis is suggested to translocate in the small intestine. In vivo it induces gene expression changes in the ileal mucosa and Peyer's patches. Stimulation of Salmonella translocation by dietary prebiotics fermented in colon suggests involvement of the colon as well. However, effects of Salmon...

journal_title：BMC microbiology

authors： Rodenburg W,Keijer J,Kramer E,Roosing S,Vink C,Katan MB,van der Meer R,Bovee-Oudenhoven IM

更新日期：2007-09-12 00:00:00

abstract：BACKGROUND:Lyme borrelia genotypes differ in their capacity to cause disseminated disease. Gene array analysis was employed to profile the host transcriptome induced by Borrelia burgdorferi strains with different capacities for causing disseminated disease in the blood of C3H/HeJ mice during early infection. RESULTS:B...

journal_title：BMC microbiology

authors： Petzke MM,Iyer R,Love AC,Spieler Z,Brooks A,Schwartz I

更新日期：2016-03-08 00:00:00

abstract：BACKGROUND:Bacteriocins are antimicrobial proteins and peptides ribosomally synthesized by some bacteria which can effect both intraspecies and interspecies killing. RESULTS:Moraxella catarrhalis strain E22 containing plasmid pLQ510 was shown to inhibit the growth of M. catarrhalis strain O35E. Two genes (mcbA and mcb...

journal_title：BMC microbiology

authors： Attia AS,Sedillo JL,Hoopman TC,Liu W,Liu L,Brautigam CA,Hansen EJ

更新日期：2009-09-25 00:00:00

abstract：BACKGROUND:Most group A streptococcal (GAS) vaccine strategies have focused on the surface M protein, a major virulence factor of GAS. The amino-terminus of the M protein elicits antibodies, that are both opsonic and protective, but which are type specific. J14, a chimeric peptide that contains 14 amino acids from the ...

journal_title：BMC microbiology

authors： Yoonim N,Olive C,Pruksachatkunakorn C,Pruksakorn S

更新日期：2006-08-09 00:00:00

abstract：BACKGROUND:Xanthophyllomyces dendrorhous is a basidiomycetous yeast that synthesizes astaxanthin, a carotenoid with great biotechnological impact. The ergosterol and carotenoid synthetic pathways derive from the mevalonate pathway and involve cytochrome P450 enzymes. Among these enzymes, the CYP51 family, which is invo...

journal_title：BMC microbiology

authors： Leiva K,Werner N,Sepúlveda D,Barahona S,Baeza M,Cifuentes V,Alcaíno J

更新日期：2015-04-25 00:00:00

abstract：BACKGROUND:Famous Chinese strong-flavored liquor (CSFL) is brewed by microbial consortia in a special fermentation pit (FT). However, the fermentation process was not fully understood owing to the complicate community structure and metabolism. In this study, the process-related dynamics of microbial communities and mai...

journal_title：BMC microbiology

authors： Zhang Y,Zhu X,Li X,Tao Y,Jia J,He X

更新日期：2017-09-15 00:00:00

abstract：BACKGROUND:Bacterial lipoproteins often play important roles in pathogenesis and can stimulate protective immune responses. Such lipoproteins are viable vaccine candidates. Haemophilus ducreyi, which causes the sexually transmitted disease chancroid, expresses a number of lipoproteins during human infection. One such l...

journal_title：BMC microbiology

authors： Janowicz DM,Zwickl BW,Fortney KR,Katz BP,Bauer ME

更新日期：2014-06-24 00:00:00

abstract：BACKGROUND:Alpha (alpha)-hemolysin is a pore forming cytolysin and serves as a virulence factor in intestinal and extraintestinal pathogenic strains of E. coli. It was suggested that the genes encoding alpha-hemolysin (hlyCABD) which can be found on the chromosome and plasmid, were acquired through horizontal gene tran...

journal_title：BMC microbiology

authors： Burgos Y,Beutin L

更新日期：2010-07-19 00:00:00

abstract：BACKGROUND:Bacillus sp. H2O-1, isolated from the connate water of a Brazilian reservoir, produces an antimicrobial substance (denoted as AMS H2O-1) that is active against sulfate reducing bacteria, which are the major bacterial group responsible for biogenic souring and biocorrosion in petroleum reservoirs. Thus, the u...

journal_title：BMC microbiology

authors： Korenblum E,de Araujo LV,Guimarães CR,de Souza LM,Sassaki G,Abreu F,Nitschke M,Lins U,Freire DM,Barreto-Bergter E,Seldin L

更新日期：2012-11-07 00:00:00

abstract：BACKGROUND:Mycoplasma pneumoniae has previously been characterized as a micro-organism that is genetically highly stable. In spite of this genetic stability, homologous DNA recombination has been hypothesized to lie at the basis of antigenic variation of the major surface protein, P1, of M. pneumoniae. In order to iden...

journal_title：BMC microbiology

authors： Sluijter M,Hoogenboezem T,Hartwig NG,Vink C

更新日期：2008-10-02 00:00:00

abstract：BACKGROUND:Bovine tuberculosis (bTB) caused by Mycobacterium bovis is the most serious endemic disease affecting livestock in the UK. The European badger (Meles meles) is the most important wildlife reservoir of bTB transmission to cattle, making eradication particularly difficult. In this respect, oral vaccination wit...

journal_title：BMC microbiology

authors： Stedman A,Maluquer de Motes C,Lesellier S,Dalley D,Chambers M,Gutierrez-Merino J

更新日期：2018-07-13 00:00:00

abstract：BACKGROUND:Staphylococcus aureus (S. aureus) is one of the primary causes of bone infections which are often chronic and difficult to eradicate. Bacteria like S. aureus may survive upon internalization in cells and may be responsible for chronic and recurrent infections. In this study, we compared the responses of a ph...

journal_title：BMC microbiology

authors： Hamza T,Li B

更新日期：2014-07-25 00:00:00

abstract：BACKGROUND:The skin microbiome serves as a first line defense against pathogens in vertebrates. In amphibians, it has the potential to protect against the chytrid fungus Batrachochytrium dendrobatis (Bd), a likely agent of amphibian declines. Alteration of the microbiome associated with unfavorable environmental change...

journal_title：BMC microbiology

authors： Jiménez RR,Alvarado G,Sandoval J,Sommer S

更新日期：2020-09-22 00:00:00

abstract：BACKGROUND:Mannheimia haemolytica strains isolated from North American cattle have been classified into two genotypes (1 and 2). Although members of both genotypes have been isolated from the upper and lower respiratory tracts of cattle with or without bovine respiratory disease (BRD), genotype 2 strains are much more ...

journal_title：BMC microbiology

authors： Clawson ML,Schuller G,Dickey AM,Bono JL,Murray RW,Sweeney MT,Apley MD,DeDonder KD,Capik SF,Larson RL,Lubbers BV,White BJ,Blom J,Chitko-McKown CG,Brichta-Harhay DM,Smith TPL

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:The dspA (hik33) gene, coding for a putative sensory histidine kinase, is conserved in plastids (ycf26) and cyanobacteria. It has been linked with a number of different stress responses in cyanobacteria. RESULTS:We constructed an insertional mutant of dspA (ycf26) in Synechocystis 6803. We found little phen...

journal_title：BMC microbiology

authors： Morrison SS,Mullineaux CW,Ashby MK

更新日期：2005-08-02 00:00:00

abstract：BACKGROUND:Enterobacter sakazakii is an emergent pathogen associated with ingestion of infant formula and accurate identification is important in both industrial and clinical settings. Bacterial species can be difficult to accurately characterise from complex biochemical datasets and computer algorithms can potentially...

journal_title：BMC microbiology

authors： Iversen C,Lancashire L,Waddington M,Forsythe S,Ball G

更新日期：2006-03-13 00:00:00