Abstract：
OBJECTIVE:To examine the long-term relationship between sleep duration and type 2 diabetes or impaired glucose tolerance (IGT). METHODS:Body composition measurements and self-reported sleep duration were determined in a longitudinal sample of 276 individuals aged 21 to 64 years followed for a mean of 6 years. Risk factors of type 2 diabetes/IGT over the follow-up were determined and relative risks (RRs) calculated for the development of type 2 diabetes/IGT by sleep duration group. RESULTS:Independent risk factors of type 2 diabetes/IGT over the follow-up included age, obesity, sleep duration, and glucose/insulin homeostasis indicators. Using adults with 7-8h of sleep as a reference, the adjusted RR for the development of type 2 diabetes/IGT was 2.78 (1.61-4.12) for those with 6h of sleep and 2.54 (1.42-3.53) for those with 9h of sleep. These elevated RRs remained significant after adjustment for body mass index, waist circumference or percent body fat. CONCLUSION:Short and long sleeping times are associated with a higher risk of developing type 2 diabetes/IGT, independent of several covariates. These results suggest that sleep duration may represent a novel risk factor for type 2 diabetes/IGT.
journal_name
Sleep Medjournal_title
Sleep medicineauthors
Chaput JP,Després JP,Bouchard C,Astrup A,Tremblay Adoi
10.1016/j.sleep.2008.09.016subject
Has Abstractpub_date
2009-09-01 00:00:00pages
919-24issue
8eissn
1389-9457issn
1878-5506pii
S1389-9457(08)00371-7journal_volume
10pub_type
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