Abstract:
BACKGROUND:Most studies examining psychotropic medication use on cognition in older persons with dementia include measures of global cognitive function. The present study examined the relationship between different types of psychotropic medication and specific cognitive functions in older people with dementia. METHODS:Two hundred and six institutionalized older adults with dementia (180 women, mean age 85 years) were administered neuropsychological tests. Psychotropic medication use was extracted from their medical status and categorized as: sedatives, antidepressants and antipsychotics. RESULTS:Analysis of covariance revealed that psychotropic consumers, and particularly those who used antipsychotics, performed worse on neuropsychological tests of executive/attentional functioning than non-consumers. There were no differences between consumers of other classes of psychotropic drugs and non-consumers. The number of psychotropic drugs used was inversely related to executive/attentional functioning. CONCLUSIONS:These findings show that in institutionalized older adults with dementia, specific impairment of cognitive function, i.e. executive/attentional impairments, are associated with antipsychotic medication use. Future longitudinal studies are recommended.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Eggermont LH,de Vries K,Scherder EJdoi
10.1017/S1041610209008552subject
Has Abstractpub_date
2009-04-01 00:00:00pages
286-94issue
2eissn
1041-6102issn
1741-203Xpii
S1041610209008552journal_volume
21pub_type
杂志文章abstract:BACKGROUND:This study determined the reliability, validity, and factor structure of self-report emotions in persons with mild Alzheimer's disease (AD) and mild cognitive impairment (MCI) relative to controls. METHODS:Participants (mild AD, n = 73; MCI, n = 159; controls, n = 96) rated current emotions with the Visual ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021100041X
更新日期:2011-08-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218001813
更新日期:2019-04-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210000050
更新日期:2010-08-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218002193
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Concerns about suicide risk in people with dementia have been increasing in recent years along with a discourse about rational suicide and assisted suicide. METHODS:A systematic narrative literature review of suicidal behavior and assisted suicide in persons with dementia. RESULTS:Most studies that have ex...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610215000629
更新日期:2015-10-01 00:00:00
abstract::This article discusses the role of some pathogenetical factors in the main morphological variants of vascular dementia and their correlation with certain clinical parameters. On the basis of computer-tomographical (CT) studies of 62 patients with dementia, it was possible to distinguish three groups of patients, accor...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610292001054
更新日期:1992-10-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
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更新日期:2019-12-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610220004019
更新日期:2021-01-18 00:00:00
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journal_title:International psychogeriatrics
pub_type: 评论,杂志文章
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2006-06-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610215001751
更新日期:2016-04-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/S1041610210000116
更新日期:2011-02-01 00:00:00
abstract::Understanding of vascular substrates of cognitive decline in the elderly is evolving to include a major emphasis on the impact of small vessel disease (SVD). While existing concepts of multi-infarct dementia and strategic infarct dementia remain valid, they present difficulty in generalizing clinicopathological correl...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610203008998
更新日期:2003-01-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
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更新日期:2017-01-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610205002759
更新日期:2006-09-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610215002306
更新日期:2016-06-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/s1041610297004468
更新日期:1997-09-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2020-08-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2011-02-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2000-06-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
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更新日期:2015-10-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:Cognitive impairment places older adults at increased risk of functional decline, injuries, and hospitalization. Assessments to determine whether older persons are still capable of meeting the cognitive challenges of everyday living are crucial to ensure their safe and independent living in the community. Th...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213001889
更新日期:2014-02-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章,随机对照试验
doi:10.1017/S104161021500071X
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Vocally disruptive behavior (VDB) in the elderly is a common condition, especially in people with dementia, but difficult to treat. It may occur in as many as 40% of nursing home residents. This study is a review of the existing literature on this condition. METHOD:The literature review was conducted using ...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610208006728
更新日期:2008-08-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218002144
更新日期:2019-11-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2003-01-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
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更新日期:2012-05-01 00:00:00
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journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610208007035
更新日期:2008-10-01 00:00:00