Techniques for temporal detection of neural sensitivity to external stimulation.

Abstract:

:We propose a simple measure of neural sensitivity for characterizing stimulus coding. Sensitivity is defined as the fraction of neurons that show positive responses to n stimuli out of a total of N. To determine a positive response, we propose two methods: Fisherian statistical testing and a data-driven Bayesian approach to determine the response probability of a neuron. The latter is non-parametric, data-driven, and captures a lower bound for the probability of neural responses to sensory stimulation. Both methods are compared with a standard test that assumes normal probability distributions. We applied the sensitivity estimation based on the proposed method to experimental data recorded from the mushroom body (MB) of locusts. We show that there is a broad range of sensitivity that the MB response sweeps during odor stimulation. The neurons are initially tuned to specific odors, but tend to demonstrate a generalist behavior towards the end of the stimulus period, meaning that the emphasis shifts from discrimination to feature learning.

journal_name

Biol Cybern

journal_title

Biological cybernetics

authors

Rodríguez FB,Huerta R

doi

10.1007/s00422-009-0297-6

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

289-97

issue

4

eissn

0340-1200

issn

1432-0770

journal_volume

100

pub_type

杂志文章
  • Bayesian models of eye movement selection with retinotopic maps.

    abstract::Among the various possible criteria guiding eye movement selection, we investigate the role of position uncertainty in the peripheral visual field. In particular, we suggest that, in everyday life situations of object tracking, eye movement selection probably includes a principle of reduction of uncertainty. To evalua...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-009-0292-y

    authors: Colas F,Flacher F,Tanner T,Bessière P,Girard B

    更新日期:2009-03-01 00:00:00

  • Equation of motion and general solution for the one-dimensional complex cell response in the signal-tuned approach.

    abstract::A signal-tuned approach has been recently introduced for modeling stimulus-dependent cortical receptive fields. The approach is based on signal-tuned Gabor functions, which are Gaussian-modulated sinusoids whose parameters are obtained from a "tuning" signal. Given a stimulus to a cell, it is taken as the tuning signa...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-015-0653-7

    authors: Torreão JR

    更新日期:2015-10-01 00:00:00

  • Motion control of musculoskeletal systems with redundancy.

    abstract::Motion control of musculoskeletal systems for functional electrical stimulation (FES) is a challenging problem due to the inherent complexity of the systems. These include being highly nonlinear, strongly coupled, time-varying, time-delayed, and redundant. The redundancy in particular makes it difficult to find an inv...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-008-0258-5

    authors: Park H,Durand DM

    更新日期:2008-12-01 00:00:00

  • A model for the economical encoding of the visual image in cerebral cortex.

    abstract::We propose a model for the first stage of the cortical transformation of the visual image based on the principle that the cortex encodes the information with the minimum number of channels mathematically needed. We restrict our model to be consistent with the data on size adaptations, the known relationships of acuity...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00336972

    authors: Sakitt B,Barlow HB

    更新日期:1982-01-01 00:00:00

  • Face-infringement space: the frame of reference of the ventral intraparietal area.

    abstract::Experimental studies have shown that responses of ventral intraparietal area (VIP) neurons specialize in head movements and the environment near the head. VIP neurons respond to visual, auditory, and tactile stimuli, smooth pursuit eye movements, and passive and active movements of the head. This study demonstrates ma...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-012-0491-9

    authors: McCollum G,Klam F,Graf W

    更新日期:2012-07-01 00:00:00

  • The contribution of muscle properties in the control of explosive movements.

    abstract::Explosive movements such as throwing, kicking, and jumping are characterized by high velocity and short movement time. Due to the fact that latencies of neural feedback loops are long in comparison to movement times, correction of deviations cannot be achieved on the basis of neural feedback. In other words, the contr...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00198959

    authors: van Soest AJ,Bobbert MF

    更新日期:1993-01-01 00:00:00

  • A cardioid oscillator with asymmetric time ratio for establishing CPG models.

    abstract::Nonlinear oscillators are usually utilized by bionic scientists for establishing central pattern generator models for imitating rhythmic motions by bionic scientists. In the natural word, many rhythmic motions possess asymmetric time ratios, which means that the forward and the backward motions of an oscillating proce...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-018-0746-1

    authors: Fu Q,Wang DH,Xu L,Yuan G

    更新日期:2018-06-01 00:00:00

  • Estimation of signal and noise spectra by special averaging techniques with application to a posteriori "Wiener" filtering.

    abstract::This paper deals with the problem of separating the spectra of signal and noise in ensembles where the signal can be considered as an invariant component and the noise as a stationary additive background. Several methods are discussed and compared on the basis of a statistical analysis of the first two moments of the ...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00337392

    authors: de Weerd JP,Uyen GJ,Johannesma PI,Martens WL

    更新日期:1979-03-19 00:00:00

  • A posteriori time-varying filtering of averaged evoked potentials. II. Mathematical and computational aspects.

    abstract::The problem of estimating an unknown transient signal, given an ensemble of waveforms, in which this signal appears as a nonrandom component in the presence of additive noise is considered. This problem is solved by generalizing the method of "a posteriori 'Wiener' filtering". In the new method, the ensemble average i...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00340323

    authors: de Weerd JP,Kap JI

    更新日期:1981-01-01 00:00:00

  • On the classification of normally distributed neurons: an application to human dentate nucleus.

    abstract::One of the major goals in cellular neurobiology is the meaningful cell classification. However, in cell classification there are many unresolved issues that need to be addressed. Neuronal classification usually starts with grouping cells into classes according to their main morphological features. If one tries to test...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-011-0426-x

    authors: Ristanović D,Milošević NT,Marić DL

    更新日期:2011-03-01 00:00:00

  • An elaborated model of fly small-target tracking.

    abstract::Flies have the capability to visually track small moving targets, even across cluttered backgrounds. Previous computational models, based on figure detection (FD) cells identified in the fly, have suggested how this may be accomplished at a neuronal level based on information about relative motion between the target a...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-004-0518-y

    authors: Higgins CM,Pant V

    更新日期:2004-12-01 00:00:00

  • Recognition and tracking of impulse patterns with delay adaptation in biology-inspired pulse processing neural net (BPN) hardware.

    abstract::The application of an electronic real time emulator for biology-inspired pulse processing neural networks (BPN) to recognition and temporal tracking of discrete impulse patterns via delay adaptation is demonstrated. The electronic emulation includes biologically plausible features, such as asynchronous impulses, membr...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00206711

    authors: Napp-Zinn H,Jansen M,Eckmiller R

    更新日期:1996-05-01 00:00:00

  • Washout filter aided mean field feedback desynchronization in an ensemble of globally coupled neural oscillators.

    abstract::We propose an approach for desynchronization in an ensemble of globally coupled neural oscillators. The impact of washout filter aided mean field feedback on population synchronization process is investigated. By blocking the Hopf bifurcation of the mean field, the controller desynchronizes the ensemble. The technique...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-009-0334-5

    authors: Luo M,Wu Y,Peng J

    更新日期:2009-09-01 00:00:00

  • Intrinsic variability of latency to first-spike.

    abstract::The assessment of the variability of neuronal spike timing is fundamental to gain understanding of latency coding. Based on recent mathematical results, we investigate theoretically the impact of channel noise on latency variability. For large numbers of ion channels, we derive the asymptotic distribution of latency, ...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-010-0384-8

    authors: Wainrib G,Thieullen M,Pakdaman K

    更新日期:2010-07-01 00:00:00

  • Topological maps of protein sequences.

    abstract::A new method based on neural networks to cluster proteins into families is described. The network is trained with the Kohonen unsupervised learning algorithm, using matrix pattern representations of the protein sequences as inputs. The components (x, y) of these 20 x 20 matrix patterns are the normalized frequencies o...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00204658

    authors: Ferrán EA,Ferrara P

    更新日期:1991-01-01 00:00:00

  • The frequency response function and sinusoidal threshold properties of the Hodgkin-Huxley model of action potential encoding.

    abstract::The behavior of the space-clamped Hodgkin-Huxley model has been studied using band-limited white noise (0-50 Hz) as the input membrane current and taking the output as a point process in time given by the peaks of the action potentials. The frequency response and coherence functions were measured by use of the Fourier...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00334462

    authors: French AS

    更新日期:1984-01-01 00:00:00

  • The main sequence of saccades optimizes speed-accuracy trade-off.

    abstract::In primates, it is well known that there is a consistent relationship between the duration, peak velocity and amplitude of saccadic eye movements, known as the 'main sequence'. The reason why such a stereotyped relationship evolved is unknown. We propose that a fundamental constraint on the deployment of foveal vision...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-006-0064-x

    authors: Harris CM,Wolpert DM

    更新日期:2006-07-01 00:00:00

  • Biochemical switching device realizing McCulloch-Pitts type equation.

    abstract::We analyzed cyclic enzyme systems, one of the best candidates for biochemical switching devices, especially focusing on their control mode against external perturbations. Since these systems have the reliability of ON-OFF types of operation (McCulloch-Pitts' neuronic equation), we shall present here the mechanical dif...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00363938

    authors: Okamoto M,Sakai T,Hayashi K

    更新日期:1988-01-01 00:00:00

  • Hebbian mechanisms help explain development of multisensory integration in the superior colliculus: a neural network model.

    abstract::The superior colliculus (SC) integrates relevant sensory information (visual, auditory, somatosensory) from several cortical and subcortical structures, to program orientation responses to external events. However, this capacity is not present at birth, and it is acquired only through interactions with cross-modal eve...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-012-0511-9

    authors: Cuppini C,Magosso E,Rowland B,Stein B,Ursino M

    更新日期:2012-12-01 00:00:00

  • A new algorithm for voltage clamp by iteration: a learning control of a nonlinear neuronal system.

    abstract::Voltage-clamp of excitable membrane allows the measurement of membrane currents associated with electrical potential changes across the membrane. However, it has been impossible in practice to apply the conventional analog feedback voltage-clamp circuits to single electrode voltage clamping in central neurons. The rea...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00355690

    authors: Kawato M,Etoh M,Oda Y,Tsukahara N

    更新日期:1985-01-01 00:00:00

  • The fractal dimension of a test signal: implications for system identification procedures.

    abstract::The experimental identification of a non-linear biologic transducer is often approached via consideration of its response to a stochastic test ensemble, such as Gaussian white noise (Marmarelis and Marmarelis 1978). In this approach, the input-output relationship a deterministic transducer is described by an orthogona...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00354987

    authors: Victor JD

    更新日期:1987-01-01 00:00:00

  • Physiological evidence for central modulation of voice tremor.

    abstract::The present report presents an attempt to define the physiological parameter used to describe "voice tremor" in psychological stress evaluating machines, and to find its sources. This parameter was found to be a low frequency (5-20 Hz) random process which frequency modulates the vocal cord waveform and (independently...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00340063

    authors: Inbar GF,Eden G

    更新日期:1983-01-01 00:00:00

  • Relevance of the single ommatidium performance in determining the oscillatory response of the Limulus retina.

    abstract::The response of a healthy lateral eye of Limulus to constant, uniform and sufficiently intense light stimulation, consists of a sustained oscillatory discharge, all ommatidia firing synchronously in bursts, at intervals of about 0.2s (Barlow and Fraioli, 1978). This response has been analysed by a computer simulation,...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00336944

    authors: Barbi M,Ferdeghini EM

    更新日期:1980-01-01 00:00:00

  • Cross-modal identification: effects of contingent changes in the stimulus series.

    abstract::Two computer controlled experiments in an olfactory cross-modal matching task, using two-component odour mixtures matched against bar diagrams, were designed so that stimulus presentation was contingent upon the recent performance of the subject; stimuli that were relatively poorly (in experiment 1) or well (in experi...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00336981

    authors: Gregson RA,Gates A

    更新日期:1985-01-01 00:00:00

  • Synchronizing human movement with an external clock source.

    abstract::Temporal information processing was studied in humans attempting to tap a key in synchrony with a metronome whose base period was subjected to subliminal random changes. Statistical measures of the sequential timing of metronome and key-tap events were compared with similar time series generated by computer-simulated ...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00319511

    authors: Hary D,Moore GP

    更新日期:1987-01-01 00:00:00

  • Self-stabilization of neuronal networks. II. Stability conditions for synaptogenesis.

    abstract::This study is concerned with synaptic reorganization in local neuronal networks. Within networks of 30 neurons, an initial disequilibrium in connectivity has to be compensated by reorganization of synapses. Such plasticity is not a genetically determined process, but depends on results of neuronal interaction. Neurobi...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00364134

    authors: Dammasch IE,Wagner GP,Wolff JR

    更新日期:1988-01-01 00:00:00

  • A two dimensional field theory for motion computation. First order approximation; translatory motion of rigid patterns.

    abstract::The local extraction of motion information from brightness patterns by individual movement detectors of the correlation-type is considered in the first part of the paper. A two-dimensional field theory of movement detection is developed by treating the distance between two adjacent photoreceptors as a differential. In...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00205969

    authors: Reichardt WE,Schlögl RW

    更新日期:1988-01-01 00:00:00

  • Neural network firing-rate models on integral form: effects of temporal coupling kernels on equilibrium-state stability.

    abstract::Firing-rate models describing neural-network activity can be formulated in terms of differential equations for the synaptic drive from neurons. Such models are typically derived from more general models based on Volterra integral equations assuming exponentially decaying temporal coupling kernels describing the coupli...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-007-0167-z

    authors: Nordbø O,Wyller J,Einevoll GT

    更新日期:2007-09-01 00:00:00

  • A central pattern generator to control a pyloric-based system.

    abstract::A central pattern generator (CPG) is built to control a mechanical device (plant) inspired by the pyloric chamber of the lobster. Conductance-based models are used to construct the neurons of the CPG. The plant has an associated function that measures the amount of food flowing through it per unit of time. We search f...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/PL00007963

    authors: Huerta R,Sánchez-Montañés MA,Corbacho F,Sigüenza JA

    更新日期:2000-01-01 00:00:00

  • A computational theory of visual receptive fields.

    abstract::A receptive field constitutes a region in the visual field where a visual cell or a visual operator responds to visual stimuli. This paper presents a theory for what types of receptive field profiles can be regarded as natural for an idealized vision system, given a set of structural requirements on the first stages o...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-013-0569-z

    authors: Lindeberg T

    更新日期:2013-12-01 00:00:00