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How should a nonfunctioning pituitary macroadenoma be monitored after debulking surgery?

Abstract：

:Transsphenoidal surgery is the treatment of choice for nonfunctioning pituitary macroadenomas but is seldom curative. Tumour progression rates are high in patients with postoperative remnants. Therefore, long-term monitoring is necessary to detect tumour growth, which may be asymptomatic or manifest with visual field defects and/or pituitary dysfunction. In view of the generally slow-growing nature of these tumours, yearly magnetic resonance imaging, neuro-ophthalmologic and pituitary function evaluation are appropriate during the first 3-5 years after surgery. If there is no evidence for tumour progression during this period, testing intervals may be extended thereafter.

journal_name

Clin Endocrinol (Oxf)

journal_title

Clinical endocrinology

authors

Greenman Y,Stern N

doi

10.1111/j.1365-2265.2009.03542.x

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

829-32

issue

6

eissn

0300-0664

issn

1365-2265

pii

CEN3542

journal_volume

70

pub_type

杂志文章

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