Post-training administration of corticosterone enhances consolidation of contextual fear memory and hippocampal long-term potentiation in rats.

abstract：:When placed in a novel environment, mice tend to explore for a period of time, and then reduce the level of exploration. This reduction in locomotor or exploratory behavior is known as habituation and can occur within a single session or across sessions, respectively, termed intrasession and intersession habituation. ...

journal_title：Neurobiology of learning and memory

authors： Bolivar VJ

更新日期：2009-09-01 00:00:00

abstract：:Corticosterone (CORT), the predominant glucocorticoid in rodents, elevated for 21 days damages hippocampal subregion CA3. We tested the hypothesis that CORT would impair spatial memory, a hippocampal function. In each of the three experiments, rats received daily, subcutaneous injections of either CORT (26.8 mg/kg bod...

journal_title：Neurobiology of learning and memory

authors： Coburn-Litvak PS,Pothakos K,Tata DA,McCloskey DP,Anderson BJ

更新日期：2003-07-01 00:00:00

abstract：:There is ongoing debate concerning whether new protein synthesis is necessary for, or even contributes to, memory formation and storage. This review summarizes a contemporary model proposing a role for altered protein synthesis in memory formation and its subsequent stabilization. One defining aspect of the model is t...

journal_title：Neurobiology of learning and memory

authors： Klann E,Sweatt JD

更新日期：2008-03-01 00:00:00

abstract：:MsrB1 belongs to the methionine sulfoxide reductase family, it is also known as selenoprotein R for the sake of possessing a selenocysteine residue. It has been reported that MsrB1 could interact with actin, TRPM6, clusterin, and amyloid-beta in vitro. Thus, we presumed that MsrB1 may play an important role in central...

journal_title：Neurobiology of learning and memory

authors： Shi T,Yang Y,Zhang Z,Zhang L,Song J,Ping Y,Du X,Song G,Liu Q,Li N

更新日期：2019-12-01 00:00:00

abstract：:An automated training system was used to compare the behavior of knockout (KO) mice lacking the fragile X mental retardation protein with that of wild-type (WT) mice (C57Bl/6 strain) in the acquisition and retention of olfactory discriminations. KO and WT mice did not differ in the acquisition of a four-stage nose pok...

journal_title：Neurobiology of learning and memory

authors： Larson J,Kim D,Patel RC,Floreani C

更新日期：2008-07-01 00:00:00

abstract：:Phosphodiesterase inhibitors (PDE-Is) enhance cAMP and/or cGMP signaling via reducing the degradation of these cyclic nucleotides. Both cAMP and cGMP signaling are essential for a variety of cellular functions and exert their effects both pre- and post-synaptically. Either of these second messengers relays and amplifi...

journal_title：Neurobiology of learning and memory

authors： Heckman PR,Blokland A,Ramaekers J,Prickaerts J

更新日期：2015-03-01 00:00:00

abstract：:Two experiments examined the effects of total stimulus preexposure on latent inhibition (LI) in a conditioned taste aversion procedure with rats. Experiment 1 varied the frequency and duration of saccharin preexposures. LI was an increasing function of the product of frequency x duration. Experiment 2 kept saccharin e...

journal_title：Neurobiology of learning and memory

authors： De la Casa G,Lubow RE

更新日期：1995-09-01 00:00:00

abstract：:New neurons are continually produced in the adult mammalian brain from progenitor cells located in specific brain regions, including the subgranular zone (SGZ) of the dentate gyrus of the hippocampus. We hypothesized that neurogenesis occurs in the canine brain and is reduced with age. We examined neurogenesis in the ...

journal_title：Neurobiology of learning and memory

authors： Siwak-Tapp CT,Head E,Muggenburg BA,Milgram NW,Cotman CW

更新日期：2007-09-01 00:00:00

abstract：:The impact of past history on behavior across the life span is largely unknown. This is why the role of previous experience in subsequent memory performances has been studied in a combined longitudinal (animals repeatedly tested) and cross-sectional (animals tested once at various ages) study, in male Sprague-Dawley r...

journal_title：Neurobiology of learning and memory

authors： Dellu F,Mayo W,Vallee M,Le Moal M,Simon H

更新日期：1997-03-01 00:00:00

abstract：:The healthy aging process affects the ability to learn and remember new facts and tasks. Prior work has shown that motor learning can be adversely affected by non-motor deficits, such as time. Here we investigated how age, and a dual task influence the learning and forgetting of a new walking pattern. We studied healt...

journal_title：Neurobiology of learning and memory

authors： Malone LA,Bastian AJ

更新日期：2016-02-01 00:00:00

abstract：:An increasing number of studies using human subjects substantiate the use of transcranial direct current stimulation (tDCS) as a noninvasive approach to treat various neurological symptoms. tDCS has been tested in conditions from motor to cognition dysfunctions. Performance enhancement of healthy subjects using tDCS h...

journal_title：Neurobiology of learning and memory

authors： Rohan JG,Miklasevich MK,McInturf SM,Bechmann NA,Moore RJ,Hatcher-Solis C,Jankord R

更新日期：2020-01-01 00:00:00

abstract：:Cocaine experience affects motivation structures such as the nucleus accumbens (NAc) and its major output target, the ventral pallidum (VP). Previous studies demonstrated that both NAc activity and hedonic responses change reliably as a taste cue comes to predict cocaine availability. Here we extended this investigati...

journal_title：Neurobiology of learning and memory

authors： Chan CL,Wheeler DS,Wheeler RA

更新日期：2016-04-01 00:00:00

abstract：:Recent data have demonstrated a biochemical sequence of events in the rat hippocampus that is necessary for memory formation of inhibitory avoidance behavior. The sequence initially involves the activation of three different types of glutamate receptors followed by changes in second messengers and biochemical cascades...

journal_title：Neurobiology of learning and memory

authors： Izquierdo I,Medina JH

更新日期：1997-11-01 00:00:00

abstract：:Attempts were made to further analyze the role of 5-HT1A receptors in consolidation of learning by evaluating the role of these receptors in cognitively normal and impaired animals. The effects of post-training administration of 8-OH-DPAT and 5-HT1A receptor antagonists, WAY 100135, WAY 100635, and S-UH-301, plus the ...

journal_title：Neurobiology of learning and memory

authors： Meneses A,Hong E

更新日期：1999-03-01 00:00:00

abstract：:The immunotoxin 192-saporin, infused intracerebroventricularly into rats, destroys cholinergic neurons in the basal forebrain nuclei. Doses required for complete cholinergic loss also kill some Purkinje cells. The immunotoxin OX7-saporin, when infused intraventricularly into rats, destroys Purkinje cells in a pattern ...

journal_title：Neurobiology of learning and memory

authors： Waite JJ,Wardlow ML,Power AE

更新日期：1999-05-01 00:00:00

abstract：:The study of bidirectional conditioning began more than a century ago, yet it has failed to take strong root in psychology and neuroscience. We revisit this topic by exploiting E. A. Asratyan's alternating procedure of stimulus presentation, in which both forward (e.g., A → B) and backward (e.g., B → A) training trial...

journal_title：Neurobiology of learning and memory

authors： Navarro VM,Wasserman EA

更新日期：2020-05-01 00:00:00

abstract：:Mounting evidence suggests that long-lasting, protein synthesis-dependent changes in synaptic strength accompany both the initial acquisition and subsequent recall of specific memories. Within brain areas thought to be important for learning and memory, including the hippocampus, learning-related plasticity is likely ...

journal_title：Neurobiology of learning and memory

authors： Chia C,Otto T

更新日期：2013-11-01 00:00:00

abstract：:It has been proposed that normal waking levels of acetylcholine (ACH) are important for initial memory acquisition, and that decreased ACH is critical for memory consolidation. Sleep is thought to benefit memory consolidation in part due to the predominance of low ACH levels observed during non-rapid eye movement slee...

journal_title：Neurobiology of learning and memory

authors： Tucker MA,Taylor K,Merchant R,George S,Stoddard C,Kopera K

更新日期：2018-11-01 00:00:00

abstract：:Two experiments investigated the potential facilitative effects of prior instructed awareness and predetermined learning criteria on humans' ability to make transitive inference (TI) judgments. Participants were first exposed to a learning phase and required to learn five premise pairs (A+B-, B+C-, C+D-, D+E-, E+F-). ...

journal_title：Neurobiology of learning and memory

authors： Munnelly A,Dymond S

更新日期：2014-03-01 00:00:00

abstract：:Research on how steroid hormones mediate mnemonic processes have focused on effects of 17beta-estradiol (E(2)); yet, progesterone (P(4)) co-varies with E(2) across endogenous hormonal milieu, and itself may influence cognitive processes. We investigated the hypothesis that acute P(4) treatment enhances cognitive perfo...

journal_title：Neurobiology of learning and memory

authors： Frye CA,Walf AA

更新日期：2008-07-01 00:00:00

abstract：:Numerous preclinical studies show that acute cannabinoid administration impairs cognitive performance. Almost all of this research has employed cannabinoid injections, however, whereas smoking is the preferred route of cannabis administration in humans. The goal of these experiments was to systematically determine how...

journal_title：Neurobiology of learning and memory

authors： Blaes SL,Orsini CA,Holik HM,Stubbs TD,Ferguson SN,Heshmati SC,Bruner MM,Wall SC,Febo M,Bruijnzeel AW,Bizon JL,Setlow B

更新日期：2019-01-01 00:00:00

abstract：:Growing evidence indicates that antagonists of the 5-hydroxytryptamine (serotonin) receptor(6) (5-HT(6)) improve memory and reverse amnesia although the mechanisms involved are poorly understood. Hence, in this paper RT-PCR was used to evaluate changes in mRNA expression of 5-HT(6) receptor in trained and untrained ra...

journal_title：Neurobiology of learning and memory

authors： Huerta-Rivas A,Pérez-García G,González-Espinosa C,Meneses A

更新日期：2010-01-01 00:00:00

abstract：:Neuroplastin 65 (NP65) is a brain-specific glycoprotein component of synaptic membrane, which is predominantly located in the forebrain such as the cortex, amygdala and striatum and hippocampus. Previous studies have shown that NP65 is implicated in synaptic plasticity, so it was hypothesized to play roles in cognitiv...

journal_title：Neurobiology of learning and memory

authors： Amuti S,Tang Y,Wu S,Liu L,Huang L,Zhang H,Li H,Jiang F,Wang G,Liu X,Yuan Q

更新日期：2016-01-01 00:00:00

abstract：:When trained to peck a selected position in a sagittally-oriented series of identical food containers, and then required to generalize to an identical series rotated by 90°, chicks identify as correct only the target position from the left end, while choosing the right one at chance. Here we show that when accustomed ...

journal_title：Neurobiology of learning and memory

authors： Rugani R,Vallortigara G,Vallini B,Regolin L

更新日期：2011-03-01 00:00:00

abstract：:Carbon monoxide (CO) is most often thought of as an exogenous toxin rather than as a possible endogenous nootrope. However, a limited number of studies have suggested that CO is necessary in memory processing for at least some tasks. While nitric oxide (NO) and CO are known activators of guanylyl cyclase (GC), only th...

journal_title：Neurobiology of learning and memory

authors： Cutajar MC,Edwards TM,Ng KT

更新日期：2005-05-01 00:00:00

abstract：:Previous studies have reported that drugs affecting neuromodulatory systems within the basolateral amygdala (BLA), including drugs affecting muscarinic cholinergic receptors, modulate the consolidation of many kinds of training, including contextual fear conditioning (CFC). The present experiments investigated the inv...

journal_title：Neurobiology of learning and memory

authors： Boccia MM,Blake MG,Baratti CM,McGaugh JL

更新日期：2009-01-01 00:00:00

abstract：:The efficacy of synaptic transmission between two neurons changes as a function of the history of previous activations of the synaptic connection. This history dependence can be characterized by examining the dependence of transmission on the frequency of stimulation. In this framework synaptic plasticity can also be ...

journal_title：Neurobiology of learning and memory

authors： Markram H,Gupta A,Uziel A,Wang Y,Tsodyks M

更新日期：1998-07-01 00:00:00

abstract：:We previously identified a set of 50 genes that were differentially transcribed in the hippocampal CA1 region of aged, learning-impaired rats compared to aged, superior learning animals during a Morris water maze paradigm. In the current study, we expressed three of these genes (Pctk1, Tcf12 and Ccnd1), which had show...

journal_title：Neurobiology of learning and memory

authors： Wu K,Li S,Bodhinathan K,Meyers C,Chen W,Campbell-Thompson M,McIntyre L,Foster TC,Muzyczka N,Kumar A

更新日期：2012-01-01 00:00:00

abstract：:Trace eyeblink conditioning requires animals to associate a neutral stimulus (CS) and an aversive periorbital shock (US) that occurred moment later. Acquisition in this conditioning depends on several forebrain regions including the hippocampus, medial prefrontal, and entorhinal cortices in addition to the cerebellum....

journal_title：Neurobiology of learning and memory

authors： Shearkhani O,Takehara-Nishiuchi K

更新日期：2013-02-01 00:00:00

abstract：:The single-trial passive avoidance task is a useful procedure for examining learning and memory in the young chick. However, it has recently been suggested that discrepant results reported by different laboratories are due to differences in training procedure. The present study investigated a number of parameters surr...

journal_title：Neurobiology of learning and memory

authors： Crowe SF,Hale MW

更新日期：2002-09-01 00:00:00