Typhoid vaccination: the Asian experience.

abstract：:Recombinant adenoviruses have emerged as promising viral vectors for CD8(+) T-cell vaccines. Our studies have indicated that unlike most acute infections, the CD8(+) T-cell memory population elicited by recombinant human adenovirus serotype 5 (rHuAd5) displays a dominant effector memory phenotype. Persistent, low-leve...

journal_title：Expert review of vaccines

authors： Bassett JD,Swift SL,Bramson JL

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Patent and proprietary medicine vendors (PPMVs) are widespread in communities and can potentially be used to expand access to routine immunization especially in underserved areas. In this study, we aimed to assess their readiness to implement routine immunization in Kano, Nigeria and identify factors associa...

journal_title：Expert review of vaccines

authors： Adamu AA,Gadanya MA,Jalo RI,Uthman OA,Nnaji CA,Bello IW,Wiysonge CS

更新日期：2020-04-01 00:00:00

abstract：:Introduction Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), has quickly spread around the world. Areas covered This review will discuss the available immunologic and clinical evidence to support the benefit of the influenza, pneumococcal, and tuberculosis vaccines...

journal_title：Expert review of vaccines

authors： Sultana J,Mazzaglia G,Luxi N,Cancellieri A,Capuano A,Ferrajolo C,de Waure C,Ferlazzo G,Trifirò G

更新日期：2020-10-01 00:00:00

abstract：:Serogroup B Neisseria meningitidis is the leading cause of meningococcal disease in developed countries. There is currently no vaccine offering wide-ranging protection. Development of a serogroup B polysaccharide-based vaccine has been hindered by potential risks of autoantibodies that cross-react with glycosylated ho...

journal_title：Expert review of vaccines

authors： Bai X,Borrow R

更新日期：2010-10-01 00:00:00

abstract：:Dengue vaccine introduction will likely occur soon. However, little has been published on international dengue vaccine communication and advocacy. More effort at the international level is required to review, unify and strategically disseminate dengue vaccine knowledge to endemic countries' decision makers and potenti...

journal_title：Expert review of vaccines

authors： Carvalho A,Van Roy R,Andrus J

更新日期：2016-01-01 00:00:00

abstract：:In the molecular farming area, transient expression approaches for pharmaceutical proteins production, mainly recombinant monoclonal antibodies and vaccines, were developed almost two decades ago and, to date, these systems basically depend on Agrobacterium-mediated delivery and virus expression machinery. We survey h...

journal_title：Expert review of vaccines

authors： Komarova TV,Baschieri S,Donini M,Marusic C,Benvenuto E,Dorokhov YL

更新日期：2010-08-01 00:00:00

abstract：:Inhalation of Yersinia pestis bacilli causes pneumonic plague, a rapidly progressing and exceptionally virulent disease. Extensively antibiotic-resistant Y. pestis strains exist and we currently lack a safe and effective pneumonic plague vaccine. These facts raise concern that Y. pestis may be exploited as a bioweapon...

journal_title：Expert review of vaccines

authors： Smiley ST

更新日期：2008-03-01 00:00:00

abstract：:The global burden of disease due to Streptococcus pneumoniae remains high. The licensed 7-valent pneumococcal conjugate vaccine (7vCRM, Prevenar/Prevnar) has successfully reduced invasive disease in the USA, but serotype coverage is incomplete and some evidence suggests that serotype replacement has occurred. Recently...

journal_title：Expert review of vaccines

authors： Prymula R,Schuerman L

更新日期：2009-11-01 00:00:00

abstract：INTRODUCTION:Hepatitis A, caused by hepatitis A virus (HAV), is primarily transmitted via the fecal/oral route either through ingestion of contaminated food and water or through direct contact with an infectious person. Prevalence of hepatitis A is strongly correlated with socioeconomic factors, decreasing with increas...

journal_title：Expert review of vaccines

authors： Bravo C,Mege L,Vigne C,Thollot Y

更新日期：2019-03-01 00:00:00

abstract：INTRODUCTION:Intranasal influenza vaccines are expected to confer protection among vaccine recipients by successful induction of mucosal immune response in the upper respiratory tract. Though only live attenuated influenza virus vaccines (LAIVs) are licensed and available for intranasal use in humans today, intranasal ...

journal_title：Expert review of vaccines

authors： Sano K,Ainai A,Suzuki T,Hasegawa H

更新日期：2018-08-01 00:00:00

abstract：:The cytotoxic CD8(+) T lymphocyte-mediated cellular response is important for the elimination of virus-infected cells and requires the prior recognition of short viral peptide antigens previously translocated to the endoplasmic reticulum by the transporter associated with antigen processing (TAP). However, individuals...

journal_title：Expert review of vaccines

authors： López D,Lorente E,Barriga A,Johnstone C,Mir C

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Viruses from two antigenically distinct influenza B strains have co-circulated since the mid-1980s, yet inactivated trivalent influenza vaccines (TIVs) with either the Victoria or Yamagata lineage could only provide limited protection from influenza B strain. Quadrivalent influenza vaccine (QIV) including bo...

journal_title：Expert review of vaccines

authors： Wang SY,Liu SZ,Chu K,Zhao Y,Zhu FC,Hu YM,Meng FY,Li JX,Luo L,Yang JY,Liu P,Yu J

更新日期：2017-11-01 00:00:00

abstract：:Mucosal vaccines constitute an advantageous immunization approach to achieve broad immunization against widespread diseases; however, improvements in this field are still required to expand their exploitation. As gold nanoparticles are biocompatible and can be easily functionalized with antigens, they have been propos...

journal_title：Expert review of vaccines

authors： Salazar-González JA,González-Ortega O,Rosales-Mendoza S

更新日期：2015-01-01 00:00:00

abstract：:Several live-attenuated Shigella vaccines, with well-defined mutations in specific genes, have shown great promise in eliciting significant immune responses when given orally to volunteers. These responses have been measured by evaluating antibody-secreting cells, serum antibody levels and fecal immunoglobulin A to ba...

journal_title：Expert review of vaccines

authors： Venkatesan MM,Ranallo RT

更新日期：2006-10-01 00:00:00

abstract：:Lassa virus (LASV) is the most prevalent arenavirus in West Africa and is responsible for several hundred thousand infections and thousands of deaths annually. The sizeable disease burden, numerous imported cases of Lassa fever (LF) and the possibility that LASV can be used as an agent of biological warfare make a str...

journal_title：Expert review of vaccines

authors： Lukashevich IS

更新日期：2013-01-01 00:00:00

abstract：:The Leishmania donovani glycoprotein fraction, known as FML, successfully underwent preclinical and clinical (Phase I-III) vaccine trials against canine visceral leishmaniasis (92-95% of protection and 76-80% of vaccine efficacy) when formulated with a QS21 saponin-containing adjuvant. It became the licensed Leishmune...

journal_title：Expert review of vaccines

authors： Palatnik-de-Sousa CB,Barbosa Ade F,Oliveira SM,Nico D,Bernardo RR,Santos WR,Rodrigues MM,Soares I,Borja-Cabrera GP

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVES:We evaluated memory responses and antibody persistence to diphtheria-toxoid, tetanus-toxoid, whole-cell-pertussis (DTwP), and Hepatitis-B vaccines in HIV-unexposed, HIV-exposed-uninfected and HIV-infected children previously randomized to initiate time-limited ART at 6-10 weeks (ART-Immed) or when clinically...

journal_title：Expert review of vaccines

authors： Simani OE,Izu A,Nunes MC,Violari A,Cotton MF,Van Niekerk N,Adrian PV,Madhi SA

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Pertussis is a highly contagious disease of the respiratory tract which is caused by the bacterium Bordetella pertussis and is most severe in those <1 year of age. A vaccine against pertussis, introduced in the 1950's, led to a significant decrease in incidence of the disease, but recent increases in outbr...

journal_title：Expert review of vaccines

authors： Martinón-Torres F,Heininger U,Thomson A,Wirsing von König CH

更新日期：2018-04-01 00:00:00

abstract：:Influenza vaccines remain the primary public health tool in reducing the ever-present burden of influenza and its complications. In seeking more immunogenic, more effective and more broadly cross-protective influenza vaccines, the landscape of influenza vaccines is rapidly expanding, both in near-term advances and nex...

journal_title：Expert review of vaccines

authors： Reber A,Katz J

更新日期：2013-05-01 00:00:00

abstract：:Tumor vaccine has been studied extensively as an alternative or adjuvant therapy in the treatment of malignant tumors in the hope of prolonging the overall survival rates of cancer patients. The efficacy largely relies on the specificity of the target. In the last decade, many antibody epitopes, called mimotopes, have...

journal_title：Expert review of vaccines

authors： Zhao L,Liu Z,Fan D

更新日期：2008-12-01 00:00:00

abstract：:Evaluation of: Böckl K, Wild J, Bredl S et al. Altering an artificial Gagpolnef polyprotein and mode of Env co-administration affects the immunogenicity of a clade C HIV-1 DNA vaccine. PLoS ONE 7(4), e34723 (2012). SIV vaccination studies in monkeys have revealed that Env-directed antibodies are critical for protect...

journal_title：Expert review of vaccines

authors： van Montfort T,Sanders RW

更新日期：2012-10-01 00:00:00

abstract：:The authors have purified a major capsid protein, VP1 of Simian virus 40 (SV40), using recombinant baculovirus and have established the method of in vitro reassembly of SV40 virus-like particles (SV40-VLPs) from VP1-pentamers. In this reassembly, SV40-VLPs can encapsulate approximately 5 kb exogenous DNA shielded by h...

journal_title：Expert review of vaccines

authors： Kawano M,Matsui M,Handa H

更新日期：2013-02-01 00:00:00

abstract：:Protection against acquisition of fully heterologous, neutralization-resistant SIV was achieved in rhesus monkeys with adenovirus/poxvirus vector-based vaccines. Protection against acquisition of infection required the inclusion of envelope antigens and correlated with the induction of binding antibodies against the E...

journal_title：Expert review of vaccines

authors： Esparza J

更新日期：2012-05-01 00:00:00

abstract：:Adjuvants are essential components of most clinically used vaccines. This is because the majority of nonliving vaccines are relatively poor inducers of adaptive immunity unless effective adjuvants are co-administered. Aluminum salts (alum) have been used as adjuvants with great success for almost a century and have be...

journal_title：Expert review of vaccines

authors： Schijns VE,Lavelle EC

更新日期：2011-04-01 00:00:00

abstract：:It is generally believed that the role of CD4(+) T cells is to coordinate the different arms of the adaptive immune system to shape an effective response against a pathogen and regulate nonessential or deleterious activities. However, a growing body of evidence suggests that effector CD4(+) T cells can directly displa...

journal_title：Expert review of vaccines

authors： Soghoian DZ,Streeck H

更新日期：2010-12-01 00:00:00

abstract：:Dengue virus is the most significant arboviral pathogen worldwide with nearly 400 million infections annually and half the global population at risk of disease. Despite this tremendous public health burden, there are no licensed treatments or vaccines to prevent dengue in humans. Results from clinical trials of leadin...

journal_title：Expert review of vaccines

authors： Widman DG,Baric RS

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:There is a growing interest in developing curative strategies for HIV infection. Therapeutic vaccines are one of the most promising approaches. We will review the current knowledge and the new challenges in this research field. Areas covered: PubMed and ClinicalTrial.gov databases were searched to review t...

journal_title：Expert review of vaccines

authors： Leal L,Lucero C,Gatell JM,Gallart T,Plana M,García F

更新日期：2017-06-01 00:00:00

abstract：:An urgent need exists for vaccines to prevent infections caused by nontypeable Haemophilus influenzae and Moraxella catarrhalis. These bacteria cause otitis media in children, a clinical problem associated with enormous morbidity and cost. H. influenzae and M. catarrhalis also cause lower respiratory tract infections ...

journal_title：Expert review of vaccines

authors： Murphy TF

更新日期：2005-12-01 00:00:00

abstract：:The Keystone Symposia conference, Challenges of Global Vaccine Development, attracted approximately 440 scientists, physicians and students from all around the world. The conference goal was to share newly acquired knowledge regarding vaccine-induced immunity, novel technologies, childhood vaccines, preclinical models...

journal_title：Expert review of vaccines

authors： Gudmundsdotter L,Hallengärd D

更新日期：2008-02-01 00:00:00

abstract：:Recombinant, nonreplicating, human adenovirus serotype 5-vectored vaccine, known as MRKAd5, expressing three HIV-1 clade B-derived internal proteins when used in a homologous immunization regimen, did not decrease HIV-1 infection rate nor postinfection virus load in the first Phase IIb proof-of-concept trial. However,...

journal_title：Expert review of vaccines

authors： Hanke T

更新日期：2008-04-01 00:00:00