Abstract:
:Menopause occurs naturally when the ovary ceases folliculogenesis, or artificially by surgical and/or medical ablation of the ovarian function. Menopause is a hypoestrogenic state, which may adversely affect estrogen target tissues, such as the brain, skeleton and skin, as well as the cardiovascular and genitourinary systems, with resultant frequency and severity of climacteric symptoms. The climacteric symptoms, however, vary significantly among women. For decades, hormone therapy (HT) has been the mainstay and is considered the most effective for managing menopausal symptoms. The prolonged use of either single estrogen therapy or a combination therapy of estrogen and progestogen (EPT) might be associated with a slightly increased risk of breast cancer and many resultant adverse events, such as coronary heart disease, stroke and venous thromboembolism. Perhaps because the clear benefits are limited to these end points of HT in treating menopausal women, the relatively significant adverse event profiles of these women may not be enough to trigger primary care physicians to be more aggressive than they have been to date in treating climacteric symptoms of postmenopausal women. However, severe climacteric symptoms really disturb the woman's life. Some epidemiologic studies have shown that the increased risk for breast cancer after 5 years of combined EPT is similar in magnitude to other lifestyle variables, such as 10-year delayed menopause, fewer pregnancies and reduced breastfeeding, postmenopausal obesity, excessive alcohol or cigarette use, and lack of regular exercise. Furthermore, elevated serum concentrations of either endogenous or exogenous (replaced by HT) sex hormone in either pre- or postmenopausal women are associated with an increased risk of breast cancer. Finally, the increased breast cancer risk diminishes soon after discontinuing hormones, and largely disappears by 5 years after cessation. Taken together, low-dose conventional HT can be used with symptomatic menopausal women, but is worthy of further evaluation because we found the following potential benefits, including (i) low-dose oral EPT appears to be effective for the alleviation of climacteric symptoms; (ii) it has a good tolerability profile with a low incidence of the most common and problematic side effects, such as breast tenderness and an increased mammographic density. Altogether, when compared with the standard dose HT, physicians may prefer to use low-dose HT initially in managing the climacteric symptoms of postmenopausal women. Time will prove.
journal_name
Taiwan J Obstet Gynecoljournal_title
Taiwanese journal of obstetrics & gynecologyauthors
Wang PH,Horng HC,Cheng MH,Chao HT,Chao KCdoi
10.1016/S1028-4559(07)60006-0subject
Has Abstractpub_date
2007-06-01 00:00:00pages
127-34issue
2eissn
1028-4559issn
1875-6263pii
S1028-4559(07)60006-0journal_volume
46pub_type
杂志文章,评审abstract:OBJECTIVE:To assess the impact of the transobturator mid-urethral sling (MUS) procedure on female sexual function and their partners' sexual activity. MATERIALS AND METHODS:Sexually active women with stress urinary incontinence who underwent a transobturator MUS procedure at the Department of Obstetrics and Gynecology...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.tjog.2018.10.015
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:The gold standard procedure for treating patients with apical pelvic organ prolapse (POP) is sacrocolpopexy. However, no report comparing the two types of single-incision robotic sacrocolpopexy, namely, single-site robotic sacrocolpopexy (SS-RSC) and single-port robotic sacrocolpopexy (SP-RSC) exists. Therefo...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2020.10.007
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the percentage of pregnant women with negative Group B Streptococcus (GBS) screening results by culture at 35 weeks' gestation, who subsequently had positive GBS test results after 39 weeks' gestation. MATERIALS AND METHODS:From 2006 to 2007, we recruited 150 pregnant wo...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 临床试验,杂志文章
doi:10.1016/S1028-4559(09)60269-2
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:To identify characteristics and pregnancy outcomes among pregnant illicit drug users living in an urban area, and to describe trends in drug use over an 8-year period. MATERIALS AND METHODS:Data on pregnant women living in the Bangkok Metropolitan Region who delivered at our institution during 2008-2015 were...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2017.12.014
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:To examine the association of antenatal renal pelvic dilatation observed on midtrimester ultrasound screening with the presence of hydronephrosis in newborn infants. MATERIALS AND METHODS:The records of patients who received fetal ultrasound examination at 18-28 weeks' gestation from May 2008 to March 2012 w...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.08.007
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:Pregnancy-associated death is defined by the American College of Obstetricians and Gynecologists as "a death of a woman while pregnant or within 1 year of termination of pregnancy, irrespective of the cause of death." We sought to determine pregnancy-associated mortality ratio (PAMR) in Taiwan and to compare ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2016.04.007
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:Burkitt's lymphoma (BL) occurs mostly in children; bilateral ovarian involvement mimicking a gynecologic malignancy in adults is extremely rare. Here, we report a patient with BL mimicking a gynecologic tumor. CASE REPORT:A 50-year-old Taiwanese woman presented with the complaint of persistent lower abdomina...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/S1028-4559(09)60217-5
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:We present a case of triplet pregnancy with a complete hydatidiform mole, a condition carrying a significant risk to both mother and fetuses and, therefore, raising an important issue on prenatal care. CASE REPORT:A 36-year-old patient with gonadal dysgenesis and a 46,XY karyotype successfully conceived a tr...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/S1028-4559(08)60034-0
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to summarize the experience on prenatal diagnosis of Down syndrome. MATERIALS AND METHODS:The study includes a retrospective data analysis of 157 prenatally detected cases of Down syndrome, routinely diagnosed among 6448 prenatal investigations performed during a 13-year period (2002...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2017.10.004
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To investigate the incidence, management, and perinatal and long-term outcomes of term pregnancies with umbilical cord prolapse (UCP) at Mackay Memorial Hospital, Taipei, from 1998 to 2007. MATERIALS AND METHODS:For this retrospective study, we reviewed the charts, searched a computerized birth database, and...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2012.07.010
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:The purpose of the study was to compare the Quinn's Advantage fertilization medium (Q1) and the tissue culture medium 199 (TCM199) for in vitro maturation (IVM) of oocytes and ammonium production during IVM. MATERIALS AND METHODS:The immature murine oocytes were randomly added into Q1 and TCM199. Ammonium co...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2013.12.001
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to propose a method using saline lubrication and two glass slides to reduce the proportion of inadequate Pap smears. MATERIALS AND METHODS:This was a retrospective study of patients at a medical center in eastern Taiwan that performs 5000-6000 Pap smears annually. The extracted data ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2020.09.018
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:The purpose of this methodology study is to examine the relative validity of four dietary assessment methods during pregnancy and to understand the pros and cons of each method. MATERIALS AND METHODS:We recruited 181 healthy pregnant women with less than 20 weeks of gestation and collected information throug...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2014.04.007
更新日期:2014-06-01 00:00:00
abstract::Systemic administration of cytotoxic drugs is the primary treatment strategy for patients with advanced cancer. The effect of cytotoxic drugs is to disrupt the DNA of the cells, rendering them unable to replicate and finally killing them; therefore, the fundamental role of a wide range of treatment regimens is typical...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.tjog.2012.04.002
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:This study aims to identify the prevalence of bacterial vaginosis (BV) and cervicitis among 511 female workers attending gynecological examination and determine the risk factors for bacterial vaginosis and cervicitis. MATERIALS AND METHODS:This study enrolled 511 female workers attending gynecological examin...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2018.11.036
更新日期:2019-05-01 00:00:00
abstract::Breast-feeding initiation within the first half hour after birth is one of the World Health Organization recommendations. However, in most hospitals, mother-infant contact and breast-feeding initiation are delayed due to routine mother and infant care. This study aimed to determine the effect of mother-infant skin to ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,meta分析
doi:10.1016/j.tjog.2018.11.002
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to describe our experience with the diagnosis and management of acquired uterine vascular abnormalities associated with persistent human chorionic gonadotropin (hCG). Through this case series, we sought to establish our protocol for the treatment and follow-up of uterine vascular les...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2014.06.008
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:Neonatal candidiasis is a leading infectious cause of significant morbidity and mortality in premature birth mainly due to impaired physical barriers and immature immune system of fetus. Maternal pregnancy-induced hypertension (PIH) has been reported to be able to disturb the neonatal immune system, which cou...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2019.01.017
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:To understand the mechanisms of postpartum uterine involution, we investigated the uterine myometrial changes during pregnancy and the postpartum period. MATERIALS AND METHODS:Nine groups of uterine myometrial samples from mice (n = 4) were collected on gestational Day 0 (nonpregnant), Day 1, Day 2, Day 7, D...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2013.01.030
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:Ovarian malignancy is highly suspected when patients present with an ovarian cystic mass lesion accompanied with ascites. However, aside from the primary origin, a metastatic lesion should be considered, since the ovary is frequently metastasized from cancers of other organs, such as the genital tract, gastro...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/S1028-4559(09)60261-8
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:We present molecular cytogenetic characterization of a prenatally detected derivative chromosome 9 [der(9)] of unknown origin. CASE REPORT:A 35-year-old woman underwent amniocentesis at 18 weeks of gestation because of advanced maternal age, which revealed a der(9) chromosome of unknown origin. The parental ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2016.06.008
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:We present prenatal diagnosis of mosaic trisomy 8 by amniocentesis in a fetus with central nervous system abnormalities. CASE REPORT:A 39-year-old woman was found to have fetal bilateral ventriculomegaly and enlargement of the third ventricle on prenatal ultrasound at 32 weeks of gestation. Fetal magnetic re...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type:
doi:10.1016/j.tjog.2019.11.020
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:A high dose of prolonged gonadotropins can yield higher numbers of oocytes and embryos. The high dose or prolonged regimens can be associated with ovarian hyperstimulation syndrome (OHSS), multiple gestations, emotional stress, economical burden and treatment dropout. In mild stimulation lower doses and short...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2018.02.005
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:To assess the long-term outcomes of laparoscopic staging surgery (LSS) in treating patients with endometrial carcinoma. MATERIALS AND METHODS:Patients with endometrial cancer who underwent LSS between June 1995 and June 2014 were prospectively registered. Perioperative data, complications, disease recurrence...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2016.04.035
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Acardiac twin occurs in 1:35,000 pregnancies. Several techniques have been described to treat this condition. Some techniques have been suggested as golden standard; however, new are still being tried. CASE REPORT:This is a case of a 32-year-old patient who had successful ablation of the acardiac twin with H...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2014.04.033
更新日期:2016-02-01 00:00:00
abstract::Prenatal screening with alpha-fetoprotein (AFP) and ultrasonography have allowed the prenatal diagnosis of neural tube defects (NTDs) in current obstetric care, and open spina bifida has been considered a potential candidate for in utero treatment in modern pediatric surgery. This article provides an overview of mater...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1016/S1028-4559(08)60125-4
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:Comparing the safety and effectiveness of the pulsed bipolar (PK) system and conventional electrosurgery in laparoscopic myomectomy (LM). MATERIALS AND METHODS:Retrospective chart review of 194 women with symptomatic uterine fibroids undertaken LM was performed. Cases of LMs with PK cutting forceps were comp...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2009.05.002
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To assess the clinical significance of low compliance bladder (LCB) in women with lower urinary tract symptoms. MATERIALS AND METHODS:Medical records of 1490 women undergoing videourodynamic studies (VUSs) were reviewed. Comprehensive medical histories, physical examinations, bladder diaries, and results of ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.10.003
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:We present a case of fetal complete atrioventricular block, diagnosed by the M mode of two-dimensional ultrasound, that was complicated with polyhydramnios and bilateral hydrocele. CASE REPORT:The fetus was delivered at 38 weeks' gestation by caesarean section. Postpartum autoimmune survey disclosed positive...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/s1028-4559(09)60192-3
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:To examine the alteration in the cellular dynamics of the urethral tissue after a simulated birth trauma in a mouse model. MATERIALS AND METHODS:A total of 36 B6 mice received vaginal distention treatment, and four untreated mice were used as controls. Specimens were collected every 24 hours after the injury...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.10.026
更新日期:2016-10-01 00:00:00