Abstract：
OBJECTIVE:The aim of this study is to summarize the experience on prenatal diagnosis of Down syndrome. MATERIALS AND METHODS:The study includes a retrospective data analysis of 157 prenatally detected cases of Down syndrome, routinely diagnosed among 6448 prenatal investigations performed during a 13-year period (2002-2014) in a single tertiary center. RESULTS:The prevalence of diagnosed Down syndrome cases was 2.4%. Maternal age alone was indication for prenatal diagnosis in 47 cases (45.2%), increased first-/second-trimester biochemical screening test in 34 cases (21.7%), abnormal ultrasound examination in 69 cases (43.9%), positive familial history for chromosomal abnormalities in four cases, and high risk for trisomy 21 revealed by cell-free DNA testing in three cases. Ultrasound anomalies were present in total of 94 fetuses (59.8%). The most common abnormality was cystic hygroma found in 46 cases (29.3%). A regular form of Down syndrome (trisomy 21) was found in 147 cases (93.6%), Robertsonian translocation in six cases (3.8%), and mosaic form in four cases (2.6%). CONCLUSION:In prenatal diagnosis of Down syndrome noninvasive screening methods are important for estimation of individual risks, in both, young population of woman and older mothers, while conventional and molecular cytogenetic methods are essential for definite diagnosis and proper genetic counseling.
journal_name
Taiwan J Obstet Gynecoljournal_title
Taiwanese journal of obstetrics & gynecologyauthors
Vičić A,Hafner T,Bekavac Vlatković I,Korać P,Habek D,Stipoljev Fdoi
10.1016/j.tjog.2017.10.004subject
Has Abstractpub_date
2017-12-01 00:00:00pages
731-735issue
6eissn
1028-4559issn
1875-6263pii
S1028-4559(17)30243-7journal_volume
56pub_type
杂志文章abstract：OBJECTIVE:To investigate the incidence, management, and perinatal and long-term outcomes of term pregnancies with umbilical cord prolapse (UCP) at Mackay Memorial Hospital, Taipei, from 1998 to 2007. MATERIALS AND METHODS:For this retrospective study, we reviewed the charts, searched a computerized birth database, and...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2012.07.010
更新日期：2012-09-01 00:00:00
abstract：OBJECTIVES:We evaluated the role of three-dimensional power Doppler ultrasound (3D PD-US) to detect endometrial lesions in women with postmenopausal endometrial bleeding. MATERIALS AND METHODS:In this prospective observational study, from January 2009 to November 2012, we recruited 225 postmenopausal women with postme...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2013.10.043
更新日期：2015-06-01 00:00:00
abstract：OBJECTIVE:The gold standard procedure for treating patients with apical pelvic organ prolapse (POP) is sacrocolpopexy. However, no report comparing the two types of single-incision robotic sacrocolpopexy, namely, single-site robotic sacrocolpopexy (SS-RSC) and single-port robotic sacrocolpopexy (SP-RSC) exists. Therefo...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2020.10.007
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVE:To test whether the interleukin-4 (IL-4) gene polymorphisms could be used as markers of susceptibility for preeclampsia in Taiwan. MATERIALS AND METHODS:This study included 78 women with preeclampsia and 125 normal controls. A polymerase chain reaction was used to analyze the variable number of tandem repeat...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2014.04.017
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:To highlight importance of detailed ultrasound examination in fetuses with known normal karyotype (and micro-array result) from CVS. In case of markedly abnormal ultrasound result repeated karyotyping by amniocentesis should be considered. Sample should be analyzed by routine cytogenetic techniques, however a...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2018.08.021
更新日期：2018-10-01 00:00:00
abstract：:Abnormal umbilical artery flow with absent or reversed end-diastolic velocity (AREDV) during pregnancy is a strong indication of placental insufficiency. When AREDV occurs prenatally, a close follow-up or expeditious delivery should be contemplated. AREDV in the umbilical artery is associated with intraventricular hem...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/S1028-4559(09)60294-1
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVE:We present the application of non-invasive prenatal testing (NIPT) in late gestation in a pregnancy associated with intrauterine growth restriction (IUGR) and trisomy 22 confined placental mosaicism (CPM). CASE REPORT:A 35-year-old pregnant woman underwent chorionic villus sampling (CVS) at 12 weeks of gesta...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2017.09.001
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVE:Pain affects many cancer patients in advancing stages, lowering the level of their quality of life. Morphine has long been the "gold standard" for the treatment of cancer pain; however, its side effects, particularly sedation and cognitive impairment at high doses, have encouraged the use of "opioid rotation"...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2011.01.006
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:This study aims to validate the BACs-on-Beads (BoB) technology as a robust and high throughput method for pre-implantation genetic screening (PGS) for aneuploidy. MATERIAL AND METHODS:The performances with respect to the sensitivity, specificity, success rate and detection rate of this technique from new BoB...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2017.01.011
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:To present a case of malignant mixed müllerian tumor of the ovary, a rare and aggressive ovarian malignant tumor with poor prognosis. CASE REPORT:A 52-year-old woman consulted our outpatient department with complaints of abdominal distention and a firm palpable mass over her lower abdomen. Physical examinati...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/S1028-4559(10)60016-2
更新日期：2010-03-01 00:00:00
abstract：OBJECTIVE:Our previous study has shown that high expression of α2,3-sialytransferase type I was associated with advanced stage serous type epithelial ovarian cancer (EOC). The aim of the current study further attempts to evaluate the altered α 2,3-sialylation on the behavior of clear cell type EOC (C-EOC). MATERIALS A...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2018.02.015
更新日期：2018-04-01 00:00:00
abstract：:Streptococcus (S.) agalactiae colonizes in the female genitourinary and lower gastrointestinal tracts and is responsible for a wide range of infections in newborns, pregnant women and non-pregnant adults. Therefore, antibiotic prophylaxis and infection treatment against S. agalactiae is important. The aim of this stud...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.tjog.2020.07.002
更新日期：2020-09-01 00:00:00
abstract：:Laparoscopic hysterectomies increase recently due to several advantages of minimally invasive surgery. Controversy exists for laparoscopic hysterectomies for large uteri weighing >500g because some reports show increased complications and morbidities and high laparoconversion rate in the past. With familiarity of lapa...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.tjog.2011.10.003
更新日期：2011-12-01 00:00:00
abstract：:Breast-feeding initiation within the first half hour after birth is one of the World Health Organization recommendations. However, in most hospitals, mother-infant contact and breast-feeding initiation are delayed due to routine mother and infant care. This study aimed to determine the effect of mother-infant skin to ...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,meta分析
doi：10.1016/j.tjog.2018.11.002
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:Embryo culture media are important factors in IVF, which can significantly influence clinical outcome of IVF/ICSI cycles. Despite this, it is still not completely clear which formulation is most optimal and whether sequential or continuous media should be favored. MATERIALS AND METHODS:This study retrospecti...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2020.08.001
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy and toxicity of VMP regimen applied to the patients with low-risk gestational trophoblastic neoplasia (LR-GTN) treated in Anhui provincial hospital. MATERIALS AND METHODS:Between 2005 and 2017, 87 patients with low-risk gestational trophoblastic neoplasia received VMP regimen, consis...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2019.03.008
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVE:This study was aimed to identify the physical and mental state of women after delivery, to investigate the factors that influence those, and to examine the effects of postpartum care performance, which is traditionally believed to be appropriate care in Korea, on women's physical and mental status. MATERIALS...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2014.04.030
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVE:To discuss the follow-up and management of fetal ovarian cysts (FOCs) and review the current literature. CASE REPORT:A 26-year-old, gravida 2, para 0, abortus 1, Rh-negative patient was diagnosed with bilateral FOCs during ultrasound examination at 32 weeks gestation. Fetal nuchal translucency measured at 12...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/s1028-4559(08)60084-4
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVE:To compare the sex ratio of offspring born after cleavage stage embryo transfer and blastocyst transfer. MATERIALS AND METHODS:In this retrospective study of embryo transfer (ET), we included 473 offspring from 446 deliveries during the period January 2002 to December 2007. Statistical analysis was performed...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/S1028-4559(10)60006-X
更新日期：2010-03-01 00:00:00
abstract：OBJECTIVE:To determine the psychological response of cervical human papillomavirus (HPV) infected women. MATERIALS AND METHODS:Twenty oncogenic or high-risk HPV infected cases were collected by purposive sampling, and a 2-hour in-depth interview was carried out with 20 women at a tertiary referring medical center. The...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2011.01.035
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVE:Endometriosis is a chronic inflammatory disease pathologically defined as the presence of endometrial-like tissue outside the uterine cavity. It is one of the most important diseases affecting women of reproductive age. The process of endometriotic implant growth is mediated by many complex interactions of im...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2015.07.004
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVE:To assess the impact of the transobturator mid-urethral sling (MUS) procedure on female sexual function and their partners' sexual activity. MATERIALS AND METHODS:Sexually active women with stress urinary incontinence who underwent a transobturator MUS procedure at the Department of Obstetrics and Gynecology...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.tjog.2018.10.015
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:Big submucosal myoma often causes heavy menstrual bleeding and are complicated in hysterscopic surgery. High Intensity Focused Ultrasound (HIFU), is a method for myoma ablation therapy, which may benefit on size reduction, and assist following hysterscopic myomectomy. CASE REPORT:Two cases, case one,. 44-yea...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2019.04.001
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVE:To estimate the prevalence of nocturia in Taiwanese women aged 20-59 years. MATERIALS AND METHODS:A random sample of 4,549 women within the age range was selected by a multistage sampling design. Face-to-face visits with 3,537 women were completed by well-trained professional interviewers. Nocturia, accordin...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/S1028-4559(08)60107-2
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:Melilotus officinalis (L.) Pall. is commonly used for treating bronchitis, painful menstruation, hemorrhoids, kidney stones, ulcers of the eyes, earache, and hardening and swelling of uterus. The European Medicines Agency reported the use of M. officinalis orally against stomach ache, gastric ulcer, and disor...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2020.01.008
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the rates of infection of asymptomatic fetuses and mothers through fetal cord blood and maternal blood examination results. MATERIALS AND METHODS:Quantitative PCR (Q-PCR) was used to detect pathogens in maternal peripheral blood and fetal cord blood after delivery of term pregnancy at Buddhist Tz...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/S1028-4559(09)60207-2
更新日期：2006-06-01 00:00:00
abstract：OBJECTIVE:To present prenatal diagnosis and molecular cytogenetic characterization of de novo partial monosomy 1p (1p36.23→pter) and partial trisomy 20p (20p12.1→pter) associated with ventriculomegaly, ventricular septal defect and midface hypoplasia. MATERIALS, METHODS AND RESULTS:A 31-year-old, primigravid woman was...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/S1028-4559(10)60100-3
更新日期：2010-12-01 00:00:00
abstract：OBJECTIVES:The feasibility of vaginoscopic hysteroscopy combined with office endometrial biopsy after ultrasonography for management of post-menopausal vaginal bleeding (PMB). MATERIALS AND METHODS:A prospective observational study of with PMB whom attending the Outpatient Clinic of Kang Ning Hospital during a four mo...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2019.05.012
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:Pregnancy-associated death is defined by the American College of Obstetricians and Gynecologists as "a death of a woman while pregnant or within 1 year of termination of pregnancy, irrespective of the cause of death." We sought to determine pregnancy-associated mortality ratio (PAMR) in Taiwan and to compare ...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2016.04.007
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to investigate factors associated with thrombosis that may contribute to recurrent pregnancy loss (habitual abortion), specifically differences in serum levels of platelet-activating factor and thrombin-activatable fibrinolysis inhibitor (carboxypeptidase B2) between women with a his...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2015.06.013
更新日期：2016-02-01 00:00:00
