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Prenatal Group B Streptococcus test using real-time polymerase chain reaction.

Abstract：

OBJECTIVE:The aim of this study was to evaluate the percentage of pregnant women with negative Group B Streptococcus (GBS) screening results by culture at 35 weeks' gestation, who subsequently had positive GBS test results after 39 weeks' gestation. MATERIALS AND METHODS:From 2006 to 2007, we recruited 150 pregnant women who received routine GBS culture screening at 35 weeks' gestation with negative results, and who had repeat cultures and real-time polymerase chain reaction (RT-PCR) tests for GBS after 39 weeks' gestation. RESULTS:Two percent of pregnant women with GBS-negative results by culture screening at 35 weeks' gestation were GBS-positive at 39 weeks' gestation. CONCLUSION:It is necessary to perform a GBS test 4 weeks after an initial negative GBS culture at 35-37 weeks of gestation. RT-PCR provides a simple and rapid alternative method for detecting rectovaginal GBS colonization at the time of labor.

journal_name

Taiwan J Obstet Gynecol

journal_title

Taiwanese journal of obstetrics & gynecology

authors

Wei CF,She BC,Liang HS,Ling QD,Tsai CY,Yen CW,Wu HY,Tsai MS

doi

10.1016/S1028-4559(09)60269-2

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

116-9

issue

2

eissn

1028-4559

issn

1875-6263

pii

S1028-4559(09)60269-2

journal_volume

48

pub_type

临床试验,杂志文章

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