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Successful administration of recombinant human antithrombin in a pregnant Japanese woman with hereditary antithrombin deficiency.

Abstract：

OBJECTIVE:Hereditary antithrombin (AT) deficiency increases the risk of venous thromboembolism (VTE) in pregnant woman. We report the first case of administration of recombinant human antithrombin (rhAT) to a pregnant Japanese woman with AT deficiency. CASE REPORT:A 30-year-old woman, gravida 2 para 0, was referred to our hospital because of AT deficiency. Unfractionated heparin was administered from 13 weeks of gestation and rhAT was administered from labor onset. A cesarean section was performed and the patient and her baby were healthy, with no sequelae. CONCLUSION:We concluded that rhAT was effective for preventing VTE during delivery, with no potential infection risks.

journal_name

Taiwan J Obstet Gynecol

journal_title

Taiwanese journal of obstetrics & gynecology

authors

Fujibe Y,Mariya T,Mizuuchi M,Ishioka S,Yoshida M,Saito T

doi

10.1016/j.tjog.2019.09.021

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

849-851

issue

6

eissn

1028-4559

issn

1875-6263

pii

S1028-4559(19)30226-8

journal_volume

58

pub_type

杂志文章

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