Abstract：
OBJECTIVE:To investigate the relationship between placental transthyretin (TTR) level and preeclampsia. MATERIALS AND METHODS:Placental tissues from uncomplicated and preeclamptic pregnancies were analyzed using immunohistochemistry and image analysis. We measured the mean optical density (OD) of immunohistochemical staining of TTR across multiple sections using Image Pro Plus 6.0. To avoid bias, we used placental tissue array, which contained preeclamptic placentas (n=8) and the control placentas (n=6) on the same slide. RESULTS:The mean TTR OD of the syncytiotrophoblast layer of placentas (95% confidence interval) from the first trimester was higher than those from the second/third trimester, and term placentas [0.149 (0.014-0.285) for the 1(st) trimester, 0.037 (0.000-0.073) for the 2(nd)/3(rd) trimester, and 0.011 (0.035-0.056) for term; p<0.01]. Although the OD of the second/third trimester placentas appeared greater than that of term placentas, this was not statistically significant. The mean TTR OD of the syncytiotrophoblast layer of the severe preeclampsia group was lower than that of controls [0.010 (0.005-0.016) vs. 0.027 (0.013-0.041), p<0.05]. CONCLUSION:The immunohistochemical expression of TTR in the syncytiotrophoblast layer of the placenta decreased significantly after 12 weeks of gestation, paralleling the changing demands of thyroid hormone uptake into the placenta. The reduced TTR expression in the syncytiotrophoblast layer of the preeclamptic placenta might impair thyroid hormone uptake and contribute to the pathophysiology of the disease.
journal_name
Taiwan J Obstet Gynecoljournal_title
Taiwanese journal of obstetrics & gynecologyauthors
Zhu L,Baczyk D,Lye SJ,Zhang Zdoi
10.1016/j.tjog.2016.04.014subject
Has Abstractpub_date
2016-06-01 00:00:00pages
385-9issue
3eissn
1028-4559issn
1875-6263pii
S1028-4559(16)30036-5journal_volume
55pub_type
杂志文章abstract：:Intrauterine adhesion is a severe complication after intrauterine operation, Various adjuvant therapies failed to improve clinical symptoms and pregnancy rates among patients with moderate-to-severe intrauterine adhesion. At present, hyaluronic acid gel is widely used in the primary prevention of adhesion after hyster...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.tjog.2019.09.002
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVE:This study aimed to investigate the risk of birth weights over 4000 g (macrosomia) in association with following the 2009 American Institute of Medicine (AIOM) recommendations. MATERIALS AND METHODS:Seventy-six nondiabetic women who delivered a singleton, term macrosomic fetus and 82 women who delivered a si...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2013.05.001
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:To investigate the relationship between abnormal degrees of oral glucose tolerance test (OGTT) results and pregnancy outcomes. MATERIALS AND METHODS:A total of 7513 singleton pregnancies screened for gestational diabetes mellitus were enrolled in this retrospective observational study. The pregnancy outcomes...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2013.10.005
更新日期：2013-12-01 00:00:00
abstract：:Cervical cancer is not only the most frequently reported cancer among women, but also the most common female genital tract neoplasm in Taiwan. Early detection is effective, because the development, maintenance and progression of precursor lesions (cervical intraepithelial neoplasia [CIN]) evolve slowly into invasive c...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/S1028-4559(08)60004-2
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVE:To compare the safety and effectiveness of the harmonic scalpel and conventional electrosurgery in laparoscopic myomectomy (LM). MATERIALS AND METHODS:We performed a retrospective chart review of 591 women with symptomatic uterine fibroids who underwent LM. Thirty-three cases of LMs with harmonic scalpel (LM...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2015.12.023
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVE:The gold standard procedure for treating patients with apical pelvic organ prolapse (POP) is sacrocolpopexy. However, no report comparing the two types of single-incision robotic sacrocolpopexy, namely, single-site robotic sacrocolpopexy (SS-RSC) and single-port robotic sacrocolpopexy (SP-RSC) exists. Therefo...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2020.10.007
更新日期：2021-01-01 00:00:00
abstract：:The aim of the current review is to report a-CGH abnormalities identified in fetuses with prenatally diagnosed fetal malformations in whom a normal karyotype was diagnosed with conventional cytogenetic analysis. A systematic electronic search of databases (PubMed/Medline, EMBASE/SCOPUS) has been conducted from incepti...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2018.11.003
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the prevalence of daytime urinary frequency among Taiwanese women aged 60 years and older. MATERIALS AND METHODS:There were an estimated 1.25 million female residents aged 60 years and over in Taiwan in 2000. A sample of 2,410 women was selected using a multistage random sampling method. Face-to-...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/S1028-4559(09)60328-4
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:To discuss the follow-up and management of fetal ovarian cysts (FOCs) and review the current literature. CASE REPORT:A 26-year-old, gravida 2, para 0, abortus 1, Rh-negative patient was diagnosed with bilateral FOCs during ultrasound examination at 32 weeks gestation. Fetal nuchal translucency measured at 12...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/s1028-4559(08)60084-4
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the rates of infection of asymptomatic fetuses and mothers through fetal cord blood and maternal blood examination results. MATERIALS AND METHODS:Quantitative PCR (Q-PCR) was used to detect pathogens in maternal peripheral blood and fetal cord blood after delivery of term pregnancy at Buddhist Tz...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/S1028-4559(09)60207-2
更新日期：2006-06-01 00:00:00
abstract：OBJECTIVE:Human papillomavirus (HPV) has been recognized as the major etiologic agent of cervical squamous cell carcinoma. However, it has been demonstrated that HPV infection is usually a self-limited process and does not lead to significant epithelial lesions or cancer. Recent data indicate that persistent high-risk ...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2014.06.001
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVES:To study the operative outcomes of single-port laparoscopic hysterectomy in uteri greater than 500 g, using either laparoscopic assisted vaginal hysterectomy (LAVH) or laparoscopic supracervical hysterectomy (LSH). MATERIALS AND METHODS:78 patients were included in a single institute by a single surgeon fro...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2020.05.006
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:Human-embryonic-stem-cell (hESC) lines derived from chromosomally or genetically abnormal embryos obtained following preimplantation genetic diagnosis are valuable in investigating genetic disorders. MATERIALS AND METHODS:In this study, a new hESC line, Center of Clinical Reproductive Medicine 8 (CCRM8) was ...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2015.08.003
更新日期：2015-10-01 00:00:00
abstract：OBJECTIVE:In nonimmune pregnant woman, the primary infection with parvovirus B19 may lead to transplacental transmission to the fetus with variable outcomes, including congenital anemia, hydrops fetalis, fetal death or spontaneous resolution. CASE REPORT:The first case was of a 28-year-old woman, gravida 2, para 1, wh...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/s1028-4559(08)60014-5
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVE:This study was aimed to identify the physical and mental state of women after delivery, to investigate the factors that influence those, and to examine the effects of postpartum care performance, which is traditionally believed to be appropriate care in Korea, on women's physical and mental status. MATERIALS...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2014.04.030
更新日期：2015-08-01 00:00:00
abstract：:Placenta previa poses a high risk for massive hemorrhage, from the antenatal period until after Cesarean section. This condition increases the risk of maternal and neonatal mortality and morbidity. In cases of placenta previa, the prenatal prediction of sudden bleeding during pregnancy and blood loss during Cesarean s...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.tjog.2012.01.002
更新日期：2012-03-01 00:00:00
abstract：:Systemic administration of cytotoxic drugs is the primary treatment strategy for patients with advanced cancer. The effect of cytotoxic drugs is to disrupt the DNA of the cells, rendering them unable to replicate and finally killing them; therefore, the fundamental role of a wide range of treatment regimens is typical...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.tjog.2012.04.002
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVE:We present prenatal diagnosis of low-level mosaicism for tetrasomy 18p at amniocentesis in a pregnancy with a favorable outcome. CASE REPORT:A 40-year-old woman underwent amniocentesis at 17 weeks of gestation because of advanced maternal age. Amniocentesis revealed a de novo supernumerary isochromosome 18p ...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2017.10.024
更新日期：2017-12-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 临床试验,杂志文章
doi：10.1016/S1028-4559(09)60269-2
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVE:Term pregnancy with choriocarcinoma is a rare condition that can be a serious health threat to both the mother and the fetus. We present a rare case of term pregnancy with choriocarcinoma presenting as severe fetal anemia and postpartum hemorrhage. CASE REPORT:A 34-year-old woman, gravida 3 para 2, was admit...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2016.04.021
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:To analyze the benefits of external cephalic version (ECV) with epidural analgesia at term and labor induction just after the procedure. MATERIALS AND METHODS:This is a retrospective observational study with patients who did not want trying a breech vaginal delivery and decided trying an ECV with epidural an...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2017.04.018
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVE:To compare trends and rates of cesarean section delivery by indication in one academic center. MATERIALS AND METHODS:A retrospective analysis of the indications of all cesarean sections performed in Edith Wolfson Medical Center, Holon, Israel, a tertiary healthcare university facility, during 1997-2012 was d...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2014.12.014
更新日期：2016-08-01 00:00:00
abstract：OBJECTIVE:We present detection of paternal origin of fetal trisomy 21 in a pregnancy with isolated ventriculomegaly but without advanced parental age. CASE REPORT:A 29-year-old pregnant woman was admitted to the hospital at 18 weeks of gestation for tocolytic treatment because of irregular uterine contractions. Her hu...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type：
doi：10.1016/j.tjog.2020.05.025
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:The thalassemias is a group of hereditary disorders with impaired production of functional hemoglobin. In this report we described a rare case of compound heterozygous mutation of South-East Asia type hereditary persistence of fetal hemoglobin (SEA-HPFH) and β -thalassemia that allowed prenatal diagnosis to b...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2018.04.019
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVES:An increase in the proportion of male-to-female live births has raised concerns in Taiwan. Disclosure of fetal sex during prenatal screening is not allowed by the Taiwan government. Fetal sex annotation in clinical genetic reports is also prohibited. This study tested the hypothesis that the male-to-female s...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2012.09.012
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:Ovarian juvenile granulosa cell tumor has an interesting association with multiple enchondromatosis (Ollier disease and Maffucci syndrome) and should be considered a leading diagnosis when an ovarian mass is found in young patients with these conditions. Besides the association with nonskeletal malignancies, ...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2017.02.002
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:Pregnancy-associated death is defined by the American College of Obstetricians and Gynecologists as "a death of a woman while pregnant or within 1 year of termination of pregnancy, irrespective of the cause of death." We sought to determine pregnancy-associated mortality ratio (PAMR) in Taiwan and to compare ...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2016.04.007
更新日期：2016-06-01 00:00:00
abstract：:Streptococcus (S.) agalactiae colonizes in the female genitourinary and lower gastrointestinal tracts and is responsible for a wide range of infections in newborns, pregnant women and non-pregnant adults. Therefore, antibiotic prophylaxis and infection treatment against S. agalactiae is important. The aim of this stud...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.tjog.2020.07.002
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:Mucinous ovarian carcinoma (MOC) is an uncommon subtype of epithelial ovarian cancers, and the pathogenesis is still poorly understood because of its rarity. We conducted a gene set-based analysis to investigate the pathogenesis of MOC by integrating microarray gene expression datasets based on the regularity...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2016.12.016
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:This was a retrospective study of the efficacy of urethral overdilation (UOD) for women with voiding dysfunction. MATERIALS AND METHODS:Thirty-six patients diagnosed with voiding dysfunction were enrolled. The main indications for UOD included women with poor compliance (30 patients, 83.3%) and obstructive s...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2014.11.008
更新日期：2015-02-01 00:00:00
