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Term pregnancy with choriocarcinoma presenting as severe fetal anemia and postpartum hemorrhage.

Abstract：

OBJECTIVE:Term pregnancy with choriocarcinoma is a rare condition that can be a serious health threat to both the mother and the fetus. We present a rare case of term pregnancy with choriocarcinoma presenting as severe fetal anemia and postpartum hemorrhage. CASE REPORT:A 34-year-old woman, gravida 3 para 2, was admitted for profuse vaginal bleeding 2 weeks after cesarean delivery of a full-term anemic baby. Transvaginal sonography revealed a 4.7-cm×10.6-cm heterogenous lesion in the endometrial cavity. Dilatation and curettage was done and a pathologic report revealed choriocarcinoma. Metastatic workup showed lung metastasis. The patient achieved remission after eight cycles of chemotherapy in the form of etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine. There was no evidence of recurrence in the subsequent 3 years of regular follow up. CONCLUSION:Although fetomaternal hemorrhage is a rare form of presentation of choriocarcinoma, its presence should alert the physician to investigate the cause further. This chemotherapy regimen was effective in our case and the patient needed to be followed up carefully.

journal_name

Taiwan J Obstet Gynecol

journal_title

Taiwanese journal of obstetrics & gynecology

authors

Peng HH,Ng ZP,Tang YH,Chua AA,Huang KG

doi

10.1016/j.tjog.2016.04.021

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

430-3

issue

3

eissn

1028-4559

issn

1875-6263

pii

S1028-4559(16)30043-2

journal_volume

55

pub_type

杂志文章

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