The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease).

Abstract:

OBJECTIVE:Ovarian juvenile granulosa cell tumor has an interesting association with multiple enchondromatosis (Ollier disease and Maffucci syndrome) and should be considered a leading diagnosis when an ovarian mass is found in young patients with these conditions. Besides the association with nonskeletal malignancies, there is a high risk of malignant transformation of enchondroma in chondrosarcoma as was also the case in this instance. CASE REPORT:The report uses multiple images to document the representative and characteristic markers of multiple enchondromas in a 22-year-old patient with Ollier disease complicated by malignant transformation of chondrosarcoma and in whom the disease is associated with ovarian juvenile granulosa cell tumor of the right ovary. CONCLUSION:It is important to recognize that when the female patient presents with enchondromatosis and a large unilateral multilocular-solid ovarian mass, the specific diagnosis of granulosa cell tumor can be made with high accuracy.

authors

Burgetova A,Matejovsky Z,Zikan M,Slama J,Dundr P,Skapa P,Benkova K,Cibula D,Fischerova D

doi

10.1016/j.tjog.2017.02.002

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

253-257

issue

2

eissn

1028-4559

issn

1875-6263

pii

S1028-4559(17)30050-5

journal_volume

56

pub_type

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