Non-compliance in pyridoxine-dependent seizures and a way out.

Abstract:

:Pyridoxine dependency is a rare autosomal-recessive disorder causing intractable seizures in neonates and infants. Life-long therapy with pyridoxine is required for prevention of seizure recurrence and for an optimum intellectual outcome. With the availability of newer biochemical confirmatory tests, the conventional pyridoxine-withdrawal test is being used less frequently for diagnosis. This report describes an infant whose parents were non-compliant with pyridoxine therapy and proposes that pyridoxine-withdrawal test may be useful in demonstrating to parents the need for life-long pyridoxine therapy, thereby reducing non-compliance.

authors

Kumar P,Gupta VK,Mishra D

doi

10.1111/j.1440-1754.2007.01142.x

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

571-2

issue

7-8

eissn

1034-4810

issn

1440-1754

pii

JPC1142

journal_volume

43

pub_type

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