Precocious puberty in Turner syndrome.

Abstract:

:Turner syndrome (TS) affects approximately 1 in 2000 liveborn girls. It is a common cause of short stature and is often, but not universally, associated with characteristic dysmorphic features and ovarian dysgenesis. Genotype/phenotype correlation in TS is generally poor and girls with TS may occasionally have normal functioning ovarian tissue, with approximately 30-40% entering puberty, 4% achieving menarche and 1% being fertile. In this report, we describe a girl with mosaic TS who unusually experienced spontaneous precocious puberty with associated accelerated longitudinal growth during mid childhood. This case acts as a useful clinical vignette with which to highlight important aspects of diagnosis and treatment in children with TS, particularly in relation to future growth potential and issues relating to fertility.

authors

Sabin MA,Zacharin MR

doi

10.1111/j.1440-1754.2007.01219.x

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

776-8

issue

11

eissn

1034-4810

issn

1440-1754

pii

JPC1219

journal_volume

43

pub_type

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