Does umbilical cord blood glucose extraction discriminate the risk of early neonatal hypoglycaemia in at-risk newborns?

Abstract:

AIM:Despite targeting newborns at risk of hypoglycaemia based on clinical characteristics, blood glucose measured at 1 and 4 h of age is frequently normal. Identification of at-risk newborns at the greatest risk of hypoglycaemia would allow more targeted, earlier intervention. We aimed to determine the ability of calculated umbilical cord blood glucose extraction to discriminate hypoglycaemia in at-risk newborns in the first 4 h of life. METHODS:Newborns with paired arterial and venous cord blood glucose and 1 ± 4 h capillary or venous blood glucose measured using a blood gas analyser (radiometer) were retrospectively identified (n = 154). Hypoglycaemia was defined as a blood glucose ≤2.0 mmol/L. The ability of calculated umbilical cord blood glucose extraction to discriminate risk of hypoglycaemia was determined by an receiver operating characteristic (ROC) curve. RESULTS:Twenty-seven newborns (18%) had a blood glucose ≤2.0 mmol/L at either time point. Neither arterial nor venous cord blood glucose predicted early hypoglycaemia better than chance. The area under the ROC curve for umbilical cord blood glucose extraction (area under the ROC curve = 0.74, (95% confidence interval, 0.65-0.82)) was significantly better than chance and arterial or venous cord blood glucose. An umbilical cord blood glucose extraction of 16% had the best sensitivity (80%) and specificity (55%) for discriminating the risk of early hypoglycaemia. CONCLUSIONS:Umbilical cord blood glucose extraction discriminates the risk of early hypoglycaemia at 1 or 4 h of age. However, the clinical utility of this test is limited due to the low sensitivity and specificity. Its predictive value may be greater in specific subsets of at-risk newborns and warrants further investigation.

authors

Kennedy LML,Crawford TM,Andersen CC,Stark MJ

doi

10.1111/jpc.14473

subject

Has Abstract

pub_date

2019-12-01 00:00:00

pages

1476-1480

issue

12

eissn

1034-4810

issn

1440-1754

journal_volume

55

pub_type

杂志文章
  • Diagnostic accuracy of paediatric echocardiograms interpreted by individuals other than paediatric cardiologists.

    abstract:OBJECTIVE:To assess the diagnostic error rate among echocardiograms undertaken by individuals other than paediatric cardiologists in our referral area. METHODOLOGY:External group: The charts and echocardiographic results of all patients who had undergone outside echocardiograms between January 1996 and December 1999 w...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2001.00695.x

    authors: Ward CJ,Purdie J

    更新日期:2001-08-01 00:00:00

  • Partial monosomy 10q with partial trisomy 11q due to paternal balanced translocation.

    abstract::A male neonate with partial monosomy 10q and partial trisomy 11q, due to paternal balanced translocation, and who had cerebellar and olfactory lobe hypoplasia, cardiovascular defects, duodenal atresia and imperforate anus, is presented. To the best of our knowledge, this is the first report on this combination of chro...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2001.00587.x

    authors: Maruyama K,Koizumi T,Ikeda H

    更新日期:2001-04-01 00:00:00

  • Hair-thread tourniquet syndrome.

    abstract::We report a case of hair-thread tourniquet syndrome involving the labia majora of a 14-year-old autistic child. 'Hair-thread tourniquet' refers to the process whereby a thread of hair leads to the ischaemic strangulation of an appendage or other piece of tissue. Uncommonly recognized, this syndrome has gradually gaine...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章,评审

    doi:10.1111/j.1440-1754.2005.00569.x

    authors: Golshevsky J,Chuen J,Tung PH

    更新日期:2005-03-01 00:00:00

  • Barriers to the use of interpreters in emergency room paediatric consultations.

    abstract:OBJECTIVE:To identify barriers to the use of trained interpreters in emergency department (ED) paediatric consultations. METHODS:A cross-sectional survey of non-English-speaking-background (NESB) carers who presented a child aged 14 years or less to the Fairfield Hospital ED during a 3-month period was undertaken usin...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2003.00135.x

    authors: Bonacruz Kazzi G,Cooper C

    更新日期:2003-05-01 00:00:00

  • Documenting family history in children with hypercholesterolaemia: A lost opportunity.

    abstract:AIM:To determine whether information about a family history of hypercholesterolaemia or early cardiovascular disease was documented by paediatricians in children and adolescents with elevated low-density lipoprotein (LDL)-cholesterol levels. METHODS:Retrospective chart review of all children with a LDL-cholesterol lev...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/jpc.13457

    authors: Sorubarajan T,Lewis BD,Burnett JR,Martin AC

    更新日期:2017-05-01 00:00:00

  • Use of complementary and alternative medicine in children: too important to ignore.

    abstract::There is evidence that complementary and alternative medicine (CAM) is commonly being used for Australian children, however, at the same time, many doctors have little interest or understanding of the topic. Just as with mainstream treatments, CAM therapies have significant potential for adverse effects and drug inter...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2003.00236.x

    authors: South M,Lim A

    更新日期:2003-11-01 00:00:00

  • Types and timing of breastfeeding support and its impact on mothers' behaviours.

    abstract:AIM:To determine the types and timing of breastfeeding support for mothers of newborn babies and the extent to which this affects breastfeeding intentions and behaviours in a region with low rates of breastfeeding initiation and duration. METHODS:A cross-sectional study by interviewer-administrated questionnaire was u...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2009.01643.x

    authors: Kervin BE,Kemp L,Pulver LJ

    更新日期:2010-03-01 00:00:00

  • Child rearing and cultural beliefs and practices amongst Thai mothers in Victoria, Australia: implications for the sudden infant death syndrome.

    abstract:OBJECTIVE:To examine the perceptions of sudden infant death syndrome (SIDS) and to describe the role of cultural beliefs and practices on child rearing amongst Thai mothers in Victoria, Australia. METHODOLOGY:In-depth interviews and participant observation conducted with 30 Thai mothers during 1995-96. RESULTS:SIDS w...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.1998.00234.x

    authors: Rice PL,Naksook C

    更新日期:1998-08-01 00:00:00

  • Paediatric presentations to Christchurch Hospital Emergency Department during COVID-19 lockdown.

    abstract:AIM:To describe the variation in volumes and types of paediatric presentations to a tertiary emergency department in New Zealand during the national level 4 lockdown for COVID-19. METHODS:A retrospective, comparative cohort study in Christchurch Hospital Emergency Department, New Zealand. RESULTS:There was a 37% redu...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/jpc.15347

    authors: Bothara RK,Raina A,Carne B,Walls T,McCombie A,Ardagh MW,Joyce LR

    更新日期:2021-01-15 00:00:00

  • Unusual presentation of acute otomastoiditis with petrositis.

    abstract::The anatomical relationships of the middle ear, the mastoid air cells, the temporal bone and intracranial structures can lead to invasive infections. Acute mastoiditis is the most common intratemporal complication of acute otitis media. Timely management includes antimicrobial therapy, imaging including ultrasound and...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/jpc.12170

    authors: Lammers TH,Krieser DM

    更新日期:2013-09-01 00:00:00

  • Cardiac cirrhosis and hepatocellular carcinoma in a 13-year-old treated with doxorubicin microbead transarterial chemoembolization.

    abstract::Increasing numbers of children are surviving into adulthood following surgery to correct or palliate congenital heart disease. This surgery can occasionally result in long-standing elevated right heart pressures and chronic hepatic venous congestion leading to cardiac cirrhosis. We report the first paediatric case of ...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2010.01932.x

    authors: Rosenbaum J,Vrazas J,Lane GK,Hardikar W

    更新日期:2012-03-01 00:00:00

  • A novel approach to monitoring adherence to preventive therapy for tuberculosis in adolescence.

    abstract:OBJECTIVES:To evaluate the usefulness of a microelectronic tablet-dispenser for monitoring adherence to preventive therapy for tuberculosis infection in adolescents. METHODOLOGY:Twenty-one patients with positive Mantoux tests were treated with isoniazid (INH), dispensed in a microelectronic tablet-dispenser that recor...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:

    authors: Starr M,Sawyer S,Carlin J,Powell C,Newman R,Johnson P

    更新日期:1999-08-01 00:00:00

  • Alcohol use by parents who present their child to a paediatric emergency department.

    abstract:OBJECTIVES:Parental alcohol misuse exposes children to risk, but is poorly identified in paediatric settings. We aimed to (i) measure the alcohol use in parents of a sample of children attending emergency and (ii) assess the quality of documentation of this alcohol use by paediatric residents. METHOD:Parents of childr...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.1999.t01-1-00345.x

    authors: Sharma S,Llewelyn K,Jureidini J

    更新日期:1999-04-01 00:00:00

  • Perception, attitudes and knowledge regarding the 2009 swine-origin influenza A (H1N1) virus pandemic among health-care workers in Australia.

    abstract:AIM:To determine the perceptions, attitudes and knowledge of Australian health-care workers (HCWs) regarding the novel, swine-origin influenza A (H1N1) virus (S-OIV) outbreak that reached the country in early May 2009. METHODS:Self-administered, anonymous Web-based survey conducted during the early stages of the S-OIV...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2010.01820.x

    authors: Tebruegge M,Pantazidou A,Ritz N,Connell T,Bryant P,Donath S,Curtis N

    更新日期:2010-11-01 00:00:00

  • Invasive pneumococcal infection in children, 1981-92: a hospital-based study.

    abstract:OBJECTIVE:To document the pattern and sequelae of invasive pneumococcal infection in hospitalized children. METHODOLOGY:Retrospective review of Streptococcus pneumoniae (Sp) isolates from normally sterile sites from 1981 to 1992 at three paediatric centres in Sydney for demographic data, spectrum of disease, predispos...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1440-1754.1995.tb00819.x

    authors: Davis CW,McIntyre PB

    更新日期:1995-08-01 00:00:00

  • Osteomyelitis and septic arthritis due to Citrobacter freundii and Haemophilus influenzae type b.

    abstract::This report describes dual infection with Citrobacter freundii and Haemophilus influenzae type b causing septic arthritis and osteomyelitis of the elbow in a previously healthy 5-year-old boy. The patient was treated successfully with intravenous fosfomycin for 4 weeks. Infections with Citrobacter beyond the neonatal ...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.1998.00161.x

    authors: Stricker T,Fröhlich S,Nadal D

    更新日期:1998-02-01 00:00:00

  • Carbohydrate-deficient glycoprotein syndrome 1b: a new answer to an old diagnostic dilemma.

    abstract::A patient with carbohydrate-deficient glycoprotein syndrome type 1b (CDGS1b) is reported. The patient presented at 5 months of age with failure to thrive, prolonged diarrhoea, hepatomegaly and elevated serum liver transaminases. Liver biopsy showed steatosis. A low serum albumin and elevated serum liver transaminases ...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2001.00671.x

    authors: Kelly DF,Boneh A,Pitsch S,Gold H,Fietz M,Nelson P,Oliver MR

    更新日期:2001-10-01 00:00:00

  • Socio-economic, familial and perinatal factors associated with obesity in Sydney schoolchildren.

    abstract:AIM:To examine associations between socio-economic, familial and perinatal factors with overweight/obesity in 6- and 12-year-old schoolchildren. METHODS:Eligible year-1 (1765/2238, mean age 6.7 years) and year-7 students (2353/3144, mean age, 12.7 years) from a random cluster sample of 55 Sydney schools were examined ...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2011.02181.x

    authors: Gopinath B,Baur LA,Burlutsky G,Robaei D,Mitchell P

    更新日期:2012-01-01 00:00:00

  • The epidemiology of paediatric head injuries: data from a referral centre in Victoria, Australia.

    abstract:AIM:Currently, there are no population-based or hospital-based studies on the full spectrum of paediatric head injuries (HIs) in Australia. We set out to provide detailed information on the incidence rates, causes and clinical management of all severities of HI in children and adolescents at an Australian tertiary refe...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2009.01499.x

    authors: Crowe L,Babl F,Anderson V,Catroppa C

    更新日期:2009-06-01 00:00:00

  • Improvement in resuscitation knowledge after a one-day paediatric life-support course.

    abstract:OBJECTIVE:To assess the effect of a one-day paediatric life-support course on the knowledge of paediatric trainees. METHODS:A telephone survey was performed prior to and at set intervals following the course. Responses to individual questions before and after the course were analysed and an overall test score was calc...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2002.00773.x

    authors: Durojaiye L,O'Meara M

    更新日期:2002-06-01 00:00:00

  • Idiopathic necrotizing dermatitis: current management.

    abstract:OBJECTIVES:To identify and demonstrate necrotizing dermatitis in infancy; an uncommon, puzzling syndrome, in which anecdotal reporting and personal experience indicates that one third of cases may require skin grafting. Much informed discussion about the pathogenesis of this distressing syndrome centres on the role of ...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.2005.00531.x

    authors: Lui PC,Petersen D,Kimble RM,Raven RJ,Pearn JH

    更新日期:2005-01-01 00:00:00

  • Neonatal outcome in a randomized, controlled trial of low-dose aspirin in high-risk pregnancies.

    abstract:OBJECTIVE:To determine the value of low-dose aspirin in high-risk pregnancies, and assess its impact on fetal growth, as well as on perinatal mortality and morbidity. METHODOLOGY:One hundred and eight women with singleton pregnancies were enrolled in a randomized, double-blind, placebo-controlled trial of 100 mg/day a...

    journal_title:Journal of paediatrics and child health

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1440-1754.1995.tb00882.x

    authors: Leslie GI,Gallery ED,Arnold JD,Ross MR,Gyory AZ

    更新日期:1995-12-01 00:00:00

  • Dialysis and renal transplantation in children: long term and recent experience.

    abstract::The outcome of 38 children with endstage renal failure who entered a dialysis and renal transplant programme over a period of 16 years is reported. The initial care was given in an adult programme but in 1985 this was changed to a comprehensive and specifically paediatric programme. Patient survival was 97, 86 and 80%...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.1990.tb01071.x

    authors: Lewis DJ,McIver M,Scott DF,Thomson NM

    更新日期:1990-10-01 00:00:00

  • Delayed presentation of an ingested foreign body causing gastric perforation.

    abstract::Ingested foreign bodies may lead to perforation of the gastrointestinal tract. We present a case of a 14-month-old boy who presented with an unusual abdominal mass secondary to ingesting a foreign body 4 months previously. Abdominal computerized tomography scan was valuable in making this diagnosis. ...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.2001.00570.x

    authors: Lam PY,Marks MK,Fink AM,Oliver MR,Woodward A

    更新日期:2001-06-01 00:00:00

  • Serum digoxin concentration in a neonate with renal and hepatic impairment.

    abstract::This report demonstrates the questionable usefulness of monitoring digoxin concentrations using the available immunoassays in some clinical situations. The patient reported here showed three characteristics (being a neonate with hepatic and renal impairment) that are associated with the presence of digoxin-like immuno...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.1990.tb02418.x

    authors: Ti TY,Lee HS,Tan CL

    更新日期:1990-06-01 00:00:00

  • Soy infant formula and phytoestrogens.

    abstract::Soy infant formula contains high levels of the isoflavones, genistein and daidzein, which are commonly referred to as phytoestrogens. These are non-steroidal chemicals with structural similarities to estrogen. Infants consuming soy formula have high levels of circulating isoflavones. These are an order of magnitude gr...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章,评审

    doi:10.1046/j.1440-1754.2003.00178.x

    authors: Tuohy PG

    更新日期:2003-08-01 00:00:00

  • Extreme sodium derangement in a paediatric inpatient population.

    abstract:OBJECTIVE:To determine the aetiology, symptoms and outcome of extreme sodium derangement in a paediatric inpatient population. METHODOLOGY:A retrospective study of children with extreme disturbance of their plasma sodium (> or = 165 mmol/L or < or = 115 mmol/L) admitted to a tertiary referral centre during a 72-month ...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.1997.tb00986.x

    authors: Dunn K,Butt W

    更新日期:1997-02-01 00:00:00

  • Ecthyma gangrenosum as a very early herald of acute lymphoblastic leukaemia.

    abstract::Ecthyma gangrenosum is a manifestation of cutaneous infection by Pseudomonas aeruginosa. The lesion may be associated with immunocompromise, in particular neutropenia. We present a case of ecthyma gangrenosum in a previously healthy child who 3 months later developed acute lymphoblastic leukaemia; we use this to illus...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1046/j.1440-1754.1999.355389.x

    authors: Pouryousefi A,Foland J,Michie C,Cummins M

    更新日期:1999-10-01 00:00:00

  • Familial Cushing's disease with severe weight loss occurring in late childhood.

    abstract::We describe a rare case of familial Cushing's disease occurring in a 7-year-old boy, and 19 years of follow up. Our patient first presented soon after his maternal aunt had been treated for Cushing's disease. The clinical presentation was made complicated by the development of an intercurrent eating disorder resemblin...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.1997.tb00996.x

    authors: Cameron FJ,Warne GL

    更新日期:1997-02-01 00:00:00

  • An evaluation of three methods used to assess the gestational age of aboriginal neonates.

    abstract::Many Aboriginal women do not recall their last menstrual period date, so alternative methods of estimating gestational age are necessary for optimal obstetric and neonatal care. In this retrospective review of 605 Aboriginal infants born at the Royal Darwin Hospital, the gestational age was estimated by the Dubowitz m...

    journal_title:Journal of paediatrics and child health

    pub_type: 杂志文章

    doi:10.1111/j.1440-1754.1992.tb02675.x

    authors: Sayers SM,Powers JR

    更新日期:1992-08-01 00:00:00