Abstract：
OBJECTIVES:To identify and demonstrate necrotizing dermatitis in infancy; an uncommon, puzzling syndrome, in which anecdotal reporting and personal experience indicates that one third of cases may require skin grafting. Much informed discussion about the pathogenesis of this distressing syndrome centres on the role of spider envenomation; and in particular on the speculative role of the Australian White-tailed spider, Lampona cylindrata. METHODS:We present here six cases of necrotizing dermatitis treated surgically at the Royal Children's Hospital and Mater Children's Hospital in Brisbane over the period from 1991 to 1999. Clinical history, surgical details and pathological investigations were reviewed in each case. Microbiological investigation of necrotic ulcers included standard aerobic and anaerobic culture. RESULT:Nocardia and Staphylococcus were cultured in two cases, but no positive bites were witnessed and no spiders were identified by either the children or their parents. All cases were treated with silver sulphadiazine creme. Two of the infants required general anaesthesia, excision debridement and split skin grafting. The White-tailed spider, Lampona cylindrata, does not occur in Queensland, but Lampona murina does; neither species has necrotizing components in its venom. Circumstantial evidence is consistent with this syndrome being due to invertebrate envenomation, possibly following arachnid bites. CONCLUSION:In our experience there is insufficient evidence to impute a specific genus as the cause, at this stage of scientific knowledge. If the offending creature is a spider, we calculate that the syndrome of necrotizing dermatitis occurs in less than 1 in 5000 spider bites.
journal_name
J Paediatr Child Healthjournal_title
Journal of paediatrics and child healthauthors
Lui PC,Petersen D,Kimble RM,Raven RJ,Pearn JHdoi
10.1111/j.1440-1754.2005.00531.xkeywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
27-30issue
1-2eissn
1034-4810issn
1440-1754pii
JPC531journal_volume
41pub_type
杂志文章abstract：:Intoxications, both accidental and intentional, are common in children and adolescents and often require hospitalisation and intensive treatment. Antiepileptic drugs are a possible cause of poisoning and intoxications because this category of medications has shown a rising trend in recent years. They might be responsi...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
doi：10.1111/jpc.13833
更新日期：2018-05-01 00:00:00
abstract：INTRODUCTION:Propranolol has recently emerged as an effective drug treatment for infantile haemangiomas. The side effect profile of the drug and the safety of administering propranolol in outpatient settings in this age group remain uncertain. We report our experience with 200 infants and children prescribed propranolo...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2012.02521.x
更新日期：2012-10-01 00:00:00
abstract：:We surveyed the directors of all 92 long day care centres in western Sydney to document the occurrence of communicable disease outbreaks during 1992 and to identify risk factors for the occurrence of these outbreaks. A total of 6092 children were enrolled at the centres, of whom 530 (8.7%) were less than 3 years old. ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1994.tb00600.x
更新日期：1994-04-01 00:00:00
abstract：AIM:Asthma is prevalent in our primary (elementary) school population. Training in asthma management for school staff should be relevant and focused on the recognition and management of an acute severe exacerbation of asthma. Evidence suggests that online training can be as effective as face-to-face training for medica...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.14080
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVES:To evaluate the usefulness of a microelectronic tablet-dispenser for monitoring adherence to preventive therapy for tuberculosis infection in adolescents. METHODOLOGY:Twenty-one patients with positive Mantoux tests were treated with isoniazid (INH), dispensed in a microelectronic tablet-dispenser that recor...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：
更新日期：1999-08-01 00:00:00
abstract：AIM:Eosinophilic oesophagitis (EoE) is a rare, chronic, relapsing immune/antigen-mediated disease characterised by symptoms of oesophageal dysfunction, with a paucity of data among New Zealand (NZ) children. This 3-year prospective study aimed to characterise EoE diagnosed nationally and to describe initial treatment s...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.15183
更新日期：2020-09-12 00:00:00
abstract：AIM:Donor selection for milk banks is essential to ensure the safety and nutritional quality of the donor milk, and to ensure that the prospective donor and her breastfeeding infant do not come to harm through donating. Australian Red Cross Lifeblood Milk went through a robust process to develop a set of criteria for t...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.14909
更新日期：2020-08-01 00:00:00
abstract：:A 5-year-old Chinese girl with 1-year history of progressive jaundice, steatorrhoea and pruritus was referred. Physical examination showed failure to thrive, marked jaundice, finger clubbing and hepatomegaly. There was laboratory evidence of cholestatic jaundice and autoimmunity, with marked elevation of alkaline phos...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00593.x
更新日期：2005-04-01 00:00:00
abstract：:Patient restraint in health care is currently under intense review. There are two disparate groups that should be considered. First, infants and young children are commonly restrained while undergoing simple medical procedures such as venepuncture or immunisation, and this practice may be better framed as 'hugging' no...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.14607
更新日期：2019-10-01 00:00:00
abstract：AIM:To review the use of antifungal chemoprophylaxis to prevent neonatal invasive fungal infections (IFI) in very low birthweight infants (VLBW <1500 g). METHOD:Systematic review of randomised controlled trials. RESULTS:Nine trials were identified (2029 infants), with six comparing fluconazole with placebo/no treatme...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,meta分析,评审
doi：10.1111/j.1440-1754.2012.02543.x
更新日期：2012-09-01 00:00:00
abstract：:Between April 1989 and October 1991, 13 severely ill infants, median age 13 days (range 1-180 days), median weight 3.5 kg (range 2.5-4.8 kg), received continuous venovenous haemofiltration (CVVH) for a median duration of 39 h (range 5-234 h). Filtration was performed through a double lumen catheter inserted into a cen...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1994.tb00566.x
更新日期：1994-02-01 00:00:00
abstract：:Recent studies have shown an association between enuresis and behavioural or emotional problems. The direction or causality of the association and its duration, however, remain unclear. This study followed a large group of children from ages 11 to 15 years and reported the prevalence of enuresis to age 13 years. The e...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1990.tb02390.x
更新日期：1990-04-01 00:00:00
abstract：:The development of educational packages on health-related topics has become common in school curricula. This paper describes an integrated health and education input in the development of an educational package about asthma for Year 8 high school students. Ownership and educational relevance of the package (ensuring i...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1994.tb00719.x
更新日期：1994-12-01 00:00:00
abstract：OBJECTIVES:Paediatric oncology patients often require repeated bone marrow aspirates and lumbar punctures. These procedures commonly require sedation and analgesia. The Australian and New Zealand College of Anaesthetists and the American Academy of Pediatrics have published guidelines that provide recommendations on mo...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00761.x
更新日期：2002-04-01 00:00:00
abstract：OBJECTIVE:To derive reference centiles for blood pressure in children aged 1-6 years which seek to address shortcomings in available reference ranges. METHODS:Prospective cohort study of 2876 children in Perth, Western Australia, commenced in 1989 with serial blood pressure measurements through early childhood obtaine...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2000.00445.x
更新日期：2000-02-01 00:00:00
abstract：OBJECTIVES:To examine the relationship between infant and parental characteristics and parental report of infant cyanosis and also hospital admission for apnoea/cyanosis. METHODS:A prospective cohort study was conducted. It involved the one-fifth of Tasmanian live births who were assessed, using a perinatal score, as ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1997.tb01608.x
更新日期：1997-08-01 00:00:00
abstract：OBJECTIVES:To document whether medically stable infants can be transferred safely from incubators to unheated, open cots at 1500 g. METHODS:Four cohorts were recruited in a stepwise observational trial of transfer from incubators to unheated, open cots. We aimed to transfer the first 15 infants into cots on reaching a...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00754.x
更新日期：2005-12-01 00:00:00
abstract：:Eight full-term infants (mean gestation 39.9 weeks [range 37-42] and mean birthweight 3642 g [range 3060-4200]) with severe respiratory failure (median oxygenation index 28 [range 16-65] and median arterial/alveolar PO2 ratio (a/APO2) 0.094 [range 0.038-0.165]) and pulmonary barotrauma were treated with Dexamethasone,...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1991.tb00421.x
更新日期：1991-12-01 00:00:00
abstract：:The public health system in Australia currently faces unprecedented challenges managing an ageing population with a rising burden of illness. Health professionals employed in the area are under constant pressure to do more with less, leading to high levels of employee dissatisfaction. Physician satisfaction is a criti...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2009.01651.x
更新日期：2010-04-01 00:00:00
abstract：AIM:This study examined the prevalence and risk factors of fine motor delay in Australian pre-school children from low-income communities. METHODS:Children from the Early Start Baseline Study completed the Ages and Stages Questionnaire (3rd edn.). Age, sex, executive function and family characteristics were assessed a...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.15152
更新日期：2021-01-01 00:00:00
abstract：:The aim of this study was to determine whether infants absorb aluminium from antacid therapy. The study was conducted at Torrens House, a service provided by Child and Adolescent Health Services (CAFHS) for feeding and settling problems. Over an 11 week period, all patients receiving antacid therapy were studied. Pati...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1992.tb02658.x
更新日期：1992-06-01 00:00:00
abstract：AIM:To identify factors that distinguish duct-dependent congenital heart disease (DDCHD) from non-DDCHD in newborn infants. METHOD:A retrospective, cohort study. The Newborn Emergency Transport Service, Victoria (NETS) is a retrieval service for all inter-hospital neonatal transfers, and the Royal Children's Hospital,...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12410
更新日期：2014-01-01 00:00:00
abstract：:We describe a 14-year-old girl with Marfan syndrome who presented with severe postural headache. Dural ectasia was demonstrated radiologically. Cerebrospinal fluid (CSF) pressure was immeasurable on formal measurement. Radionucleide cisternography failed to demonstrate a CSF leak. We consider that the underlying fibri...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00541.x
更新日期：2005-01-01 00:00:00
abstract：AIM:A retrospective Auckland-wide (total population approximately 1.4 million) study of hospital admissions from 2007 to 2015 was conducted to assess trends in admissions for acute post-streptococcal glomerulonephritis (APSGN) in children aged 0-14 years. METHODS:International Statistical Classification of Diseases (I...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.14263
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:To compare botulinum toxin A injections with fixed plaster cast stretching in the management of cerebral palsied children with dynamic (i.e. non-fixed) calf tightness. METHODS:The settings were the Women's and Children's Hospital (WCH) and the Crippled Children's Association of South Australia (CCA), Adelaid...
journal_title：Journal of paediatrics and child health
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1046/j.1440-1754.1999.00330.x
更新日期：1999-02-01 00:00:00
abstract：:Modern paediatric oncology practice has rapidly evolved from a fatal condition at diagnosis in the 1940s to modern survival rates of over 80%. With the advent of the 'omics' era and modern diagnostics platforms, we can now determine many of the molecular driving mechanisms of malignancy. Current molecular diagnostics ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.14325
更新日期：2019-01-01 00:00:00
abstract：:Clinicians practising in different regions of the world are often impressed at marked differences in disease patterns witnessed. The bases of most obvious differences are usually socio-economic and genetic, but culture and environment can be equally important. Documenting and assessing such differences is more than ju...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
doi：10.1111/j.1440-1754.1996.tb00929.x
更新日期：1996-10-01 00:00:00
abstract：:We report 36 week gestation twins born following a traumatic delivery. Twin 2 had profuse haemorrhage where haemostasis was achieved with recombinant Factor VIIa (rFVIIa - NovoSeven;Novo Nordisk A/S, Bagsvaerd, Denmark). ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2008.01446.x
更新日期：2009-01-01 00:00:00
abstract：AIMS:The aim of the study was to evaluate the significance of total bilirubin, aspartate transaminase (AST), alanine transaminase and gamma-glutamyltransferase (GGT) for predicting outcome in sepsis-associated cholestasis. METHODS:A retrospective cohort review of the hospital records was performed in 181 neonates admi...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12053
更新日期：2013-01-01 00:00:00
abstract：AIM:To report infant care practice prevalence for known modifiable sudden infant death syndrome (SIDS) risk factors among a generally disadvantaged yet low-SIDS rate population of mothers with Pacific infants. METHODS:The Pacific Islands Families study follows a cohort of Pacific infants born at a large tertiary hospi...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2007.01085.x
更新日期：2007-05-01 00:00:00
