Antiepileptic drugs: Role in paediatric poisoning.

Abstract:

:Intoxications, both accidental and intentional, are common in children and adolescents and often require hospitalisation and intensive treatment. Antiepileptic drugs are a possible cause of poisoning and intoxications because this category of medications has shown a rising trend in recent years. They might be responsible for multi-organ dysfunctions of variable severity, ranging from subtle symptoms to life-threatening complications. No guidelines on the management of these intoxications in the paediatric population are currently available, and treatment is mainly supportive. Activated charcoal administration and extracorporeal circulation techniques for drug removal have been proposed. Facing the complexity of this clinical scenario, it is of utmost importance to maintain a high index of suspicion to guarantee a prompt intervention and ensure the best possible management for the patient.

authors

Ferranti S,Grande E,Gaggiano C,Grosso S

doi

10.1111/jpc.13833

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

475-479

issue

5

eissn

1034-4810

issn

1440-1754

journal_volume

54

pub_type

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