Abstract：
AIMS:The aim of the study was to evaluate the significance of total bilirubin, aspartate transaminase (AST), alanine transaminase and gamma-glutamyltransferase (GGT) for predicting outcome in sepsis-associated cholestasis. METHODS:A retrospective cohort review of the hospital records was performed in 181 neonates admitted to the Neonatal Care Unit. A comparison was performed between subjects with low and high liver values based on cut-off values from ROC analysis. We defined poor prognosis to be when a subject had prolonged cholestasis of more than 3.5 months, developed severe sepsis, septic shock or had a fatal outcome. RESULTS:The majority of the subjects were male (56%), preterm (56%) and had early onset sepsis (73%). The poor prognosis group had lower initial values of GGT compared with the good prognosis group (P = 0.003). Serum GGT (cut-off value of 85.5 U/L) and AST (cut-off value of 51 U/L) showed significant correlation with the outcome following multivariate analysis. The odds ratio (OR) of low GGT and high AST were OR 4.3 (95% CI:1.6 to 11.8) and OR 2.9 (95% CI:1.1 to 8), respectively, for poor prognosis. In subjects with normal AST values, those with low GGT value had relative risk of 2.52 (95% CI:1.4 to 3.5) for poorer prognosis compared with those with normal or high GGT. CONCLUSION:Serum GGT and AST values can be used to predict the prognosis of patients with sepsis-associated cholestasis.
journal_name
J Paediatr Child Healthjournal_title
Journal of paediatrics and child healthauthors
Oswari H,Widjaja RK,Rohsiswatmo R,Cleghorn Gdoi
10.1111/jpc.12053subject
Has Abstractpub_date
2013-01-01 00:00:00pages
E6-11issue
1eissn
1034-4810issn
1440-1754journal_volume
49pub_type
杂志文章abstract：OBJECTIVE:To assess the effect of a one-day paediatric life-support course on the knowledge of paediatric trainees. METHODS:A telephone survey was performed prior to and at set intervals following the course. Responses to individual questions before and after the course were analysed and an overall test score was calc...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00773.x
更新日期：2002-06-01 00:00:00
abstract：:We describe three cousins who presented with agitation, dysphasia and/or coma, and developed hemiplegia following initial onset of symptoms. Two cases followed minor head injuries, two were pyrexial and two were associated with neutrophilia. Two cases required ventilatory support on the intensive care unit. Magnetic r...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2009.01465.x
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVE:To study the frequency and types of adverse reactions to currently available vaccines in very preterm infants. METHODS:Case notes were obtained for very preterm infants < or =30 weeks' gestational age who received their first immunization at the Royal Women's Hospital, Melbourne, during 1999-2003. Data were ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00663.x
更新日期：2005-08-01 00:00:00
abstract：AIM:To compare maternal reasons for non-immunisation and for partial immunisation in northern Nigeria, and determine the link between specific reasons and future intentions to immunise. METHODS:Responses to open-ended questions collected through a 2007 questionnaire survey were individually coded for key words using t...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2010.01956.x
更新日期：2011-05-01 00:00:00
abstract：:A 9 year old girl presented with seizures, weight gain and early morning behavioural changes. She had been commenced on anticonvulsants and was subsequently diagnosed with hyperinsulinaemic hypoglycaemia. This case demonstrates the importance of blood glucose monitoring in children presenting with new-onset seizures a...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12399
更新日期：2014-04-01 00:00:00
abstract：AIM:Early feeding plays an important role in programming the immune system, particularly the risk of food allergy. There are many infant feeding guides published for consumers available in Australia, with most based on the National Health and Medical Research Council (NHMRC) 2012 Infant Feeding Guidelines for Health Wo...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.13594
更新日期：2017-09-01 00:00:00
abstract：:Patient restraint in health care is currently under intense review. There are two disparate groups that should be considered. First, infants and young children are commonly restrained while undergoing simple medical procedures such as venepuncture or immunisation, and this practice may be better framed as 'hugging' no...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.14607
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVES:To assess the knowledge of pulse oximetry of senior (SMO) and junior medical officers (JMO) in a tertiary paediatric hospital. METHODS:A 16-item multiple choice questionnaire was administered to SMO and JMO without prior notice or instruction in the area. The questions were completed voluntarily and anonymo...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2003.00238.x
更新日期：2003-11-01 00:00:00
abstract：AIM:We aimed to determine, in full-term newborns born between 2000 and 2499 g, what proportion develop problems or the need for interventions that would likely require admission to a special care nursery (SCN) (i.e., needed an intravenous line (IV) or a nasogastric tube (NGT). METHODS:A multicentre, retrospective audi...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,多中心研究
doi：10.1111/jpc.12304
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:To assess the effect of reduced skin exposure in preterm infants receiving overhead phototherapy treatment on total serum bilirubin (TSB). METHODS:Randomized controlled trial. Preterm infants (>1500 g birthweight and < or = 36 weeks gestation) were randomized to being nursed either partially clothed with onl...
journal_title：Journal of paediatrics and child health
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1440-1754.2004.00362.x
更新日期：2004-05-01 00:00:00
abstract：OBJECTIVE:To assess the diagnostic error rate among echocardiograms undertaken by individuals other than paediatric cardiologists in our referral area. METHODOLOGY:External group: The charts and echocardiographic results of all patients who had undergone outside echocardiograms between January 1996 and December 1999 w...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2001.00695.x
更新日期：2001-08-01 00:00:00
abstract：AIM:To describe changes in infant prelinguistic communication skills between 8 and 12 months, and identify factors associated with those skills. METHODS: DESIGN:Parent questionnaire data for a prospective population-based cohort of infants in metropolitan Melbourne, Australia. PARTICIPANTS:1911 infants born November...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2006.00974.x
更新日期：2006-12-01 00:00:00
abstract：OBJECTIVES:We observed a reduced incidence of necrotizing enterocolitis (NEC) despite increased survival of extremely premature infants over the last two decades. A different susceptibility pattern to NEC according to gestation has been proposed. We aim to examine the influence of perinatal risk factors for NEC in infa...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00583.x
更新日期：2005-04-01 00:00:00
abstract：AIM:This study aims to examine the influence of formula milk promotion via the media from Thailand to Lao People's Democratic Republic (PDR), where a cultural and linguistic proximity are shared. METHODS:A cross-sectional study was conducted through a structured questionnaire survey and focus group discussion (FGD) wi...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12391
更新日期：2014-01-01 00:00:00
abstract：:Legal and clinical complexities surrounding consent to medical treatment for trans and gender diverse (TGD) youth in Australia continue to develop. New Australian Standards of Care and Treatment Guidelines have also introduced substantial clinical developments. Significant changes to legal principles from court decisi...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.15181
更新日期：2020-12-01 00:00:00
abstract：:We present a case of pemphigus vulgaris (PV) accompanied with protein-losing gastroenteropathy (PLE). A 9-year-old girl developed multiple oral ulcerations and erosions. She was first treated with oral antibiotics and a topical steroid without improvement. Laboratory data showed eosinophilia (absolute eosinophil count...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2007.01277.x
更新日期：2008-03-01 00:00:00
abstract：:There is increasing evidence that hyperthermia can occur in cool climates because of overwrapping and that this practice precedes many deaths labelled as SIDS. We have attempted to test the hypothesis that the interaction of a cold face and a hot body might lead to further hyperthermia in a piglet model. Twelve non-se...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1992.tb02730.x
更新日期：1992-01-01 00:00:00
abstract：:Acute appendicitis is the most common reason for abdominal surgery in children. Luminal obstruction of the appendix progresses to suppurative inflammation and perforation, which causes generalised peritonitis or an appendix mass/abscess. Classical features include periumbilical pain that migrates to the right iliac fo...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
doi：10.1111/jpc.13737
更新日期：2017-11-01 00:00:00
abstract：AIM:The aim of this study is to compare the high-frequency pressure amplitude (oscillatory change in pressure (ΔP)) and tidal volume (high-frequency tidal volume at the airway opening (VTHF )) delivered by the Dräger VN500 (Drägerwerk Ag & Co., Lübeck, Germany) and the Sensormedics 3100 (SM3100; CareFusion, San Diego, ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12398
更新日期：2014-01-01 00:00:00
abstract：:Exercise-associated hyponatraemia is a potentially serious acute condition that may present early as asymptomatic or mildly symptomatic. Standard treatment is intravenous hypertonic saline, which can be challenging and carries some risk. An alternative may be oral therapy. We undertook a review of existing literature ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
doi：10.1111/jpc.13521
更新日期：2017-05-01 00:00:00
abstract：AIM:To examine the differences in return to work time after childbirth; the differences in income; and the differences in out of pocket health-care costs between mothers who had a preterm birth and mothers who delivered a full term baby in Australia. METHODS:Using administrative data, the length of time and 'risk' of ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.15278
更新日期：2021-01-10 00:00:00
abstract：OBJECTIVE:To report a family in which congenital fibre type disproportion (CFTD) and minicore disease have been observed in members of the same family, and raise the question of the relationship between CFTD and minicores. METHODOLOGY:A follow-up clinical and biopsy study of a girl who presented to hospital because of...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1995.tb00797.x
更新日期：1995-06-01 00:00:00
abstract：:Bloody nipple discharge is a rare but distressing finding in neonates and infants. We report an 8-month-old boy who showed bilateral bloody nipple discharge for 5 months without signs of infection. Ultrasound examination revealed dilated mammary ducts. This benign phenomenon is most likely caused by mammary duct ectas...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2003.00118.x
更新日期：2003-03-01 00:00:00
abstract：:We describe three infants born to mothers with poorly controlled Graves' disease, who developed transient central hypothyroidism in the immediate postnatal period. Suppression of the fetal pituitary-thyroid axis may be due to placental transfer of thyroxine from the hyperthyroid mother. This may persist for months pos...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00741.x
更新日期：2002-04-01 00:00:00
abstract：AIM:To report on two cases of childhood thyroid minimally invasive follicular carcinoma (MIFC) to highlight the clinical features, laboratory findings and diagnosis of this rare disease. METHODS:The patients' age, gender, clinical features, laboratory findings, pathology and therapy were reviewed. Immunohistochemistry...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2009.01656.x
更新日期：2010-04-01 00:00:00
abstract：AIM:To describe the prevalence of nicotine dependence and acceptance of nicotine replacement therapy (NRT) in young people entering custody, where smoking is not allowed. METHODS:Cross-sectional study in 2013. SETTING:All New South Wales Juvenile Justice Centres. PARTICIPANTS:Incarcerated youth, aged 12-21 years. M...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.13526
更新日期：2017-07-01 00:00:00
abstract：OBJECTIVE:To identify which clinical situations are the most difficult to manage for general paediatricians in Victoria, Australia. METHODS:Self-administered questionnaires were sent to general paediatricians in Victoria. They were asked their opinions regarding what were the most difficult and the most dangerous clin...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00017.x
更新日期：2002-10-01 00:00:00
abstract：:Congenital chylothorax is the accumulation of lymphatic fluid within the pleural space. Cases unresponsive to conservative management usually require surgery. Octreotide has been used successfully to treat post-traumatic chylothoraces in the paediatric and adult population. Its exact mode of action is uncertain but it...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
doi：10.1111/j.1440-1754.2004.00471.x
更新日期：2004-09-01 00:00:00
abstract：AIMS:To describe the developmental progress of very premature babies at the age of 2 years, who were managed in an era where nasal prong continuous positive airway pressure (CPAP) was the preferred method for the management of initial respiratory disease. METHODS:Two groups of very premature babies of <32 weeks gestat...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2007.01115.x
更新日期：2007-06-01 00:00:00
abstract：AIM:The aim of this study was to undertake a retrospective review of admissions and discharges to the neonatal unit at the National Hospital Guido Valadares, Dili, in order to gain insight into the epidemiology of hospitalised neonates in East Timor, as the information cannot be obtained from the hospital health manage...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12209
更新日期：2013-06-01 00:00:00
