Abstract：
:Eight full-term infants (mean gestation 39.9 weeks [range 37-42] and mean birthweight 3642 g [range 3060-4200]) with severe respiratory failure (median oxygenation index 28 [range 16-65] and median arterial/alveolar PO2 ratio (a/APO2) 0.094 [range 0.038-0.165]) and pulmonary barotrauma were treated with Dexamethasone, 0.5 mg/kg per day, from the median age of 5 days (range 3-22). Six of the eight (75%) infants survived. They were weaned from mechanical ventilation and extubated a median of 2.5 days after commencing treatment with Dexamethasone. Two infants died and one of them suffered recurrent pneumothoraces. There was a significant improvement in oxygenation in the seven infants who survived the 72 h period of observation. Their median oxygenation index was 24 when Dexamethasone was commenced compared with 8 after 12 h (P less than 0.05) and 10 after 36 h (P less than 0.025). Their a/APO2 ratio was 0.095 when Dexamethasone was commenced compared with 0.289 after 12 h (P less than 0.05) and 0.207 after 36 h (P less than 0.025). There was a significant increase in the infants' arterial mean blood pressure associated with Dexamethasone therapy and one infant developed Staphylococcus aureus septicaemia. In this uncontrolled study of eight full-term infants with severe respiratory failure and pulmonary barotrauma, the use of Dexamethasone was associated with significant improvement in oxygenation and rapid weaning from mechanical ventilation.
journal_name
J Paediatr Child Healthjournal_title
Journal of paediatrics and child healthauthors
Barr Pdoi
10.1111/j.1440-1754.1991.tb00421.xsubject
Has Abstractpub_date
1991-12-01 00:00:00pages
366-9issue
6eissn
1034-4810issn
1440-1754journal_volume
27pub_type
杂志文章abstract：:The clinical course of a term neonate (birthweight 3.14 kg) who developed thrombosis of the left common and internal iliac veins on day 21 following recovery from Streptococcus mitis septicemia, with shock diagnosed on day 13, is reported. Subcutaneous low molecular weight heparin (LMWH) was commenced (1.5 mg/kg 12 ho...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00052.x
更新日期：2002-12-01 00:00:00
abstract：AIM:The aim of this study was to determine the frequency, risk factors and anthropometric measurements of fetally malnourished, liveborn singleton term neonates. METHODS:The computed delivery room data of 11.741 liveborn singleton term neonates was used to compare malnourished and nourished newborns. RESULTS:Of the t...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2012.02520.x
更新日期：2012-10-01 00:00:00
abstract：AIM:This study compared the outcomes of patients with biliary atresia (BA) treated according to a standardised protocol with historical patients. METHODS:This is a single-centred retrospective study of BA patients treated from 1980 to 2016. A standardised treatment protocol was established since 2008 regarding peri-op...
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
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更新日期：2017-11-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2006.00828.x
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:To determine whether umbilical cord blood glucose correlates with subsequent hypoglycaemia after birth in infants of well-controlled diabetic mothers. METHODOLOGY:Thirty-eight term infants of well-controlled diabetic mothers were enrolled. Five mothers had pre-existing diabetes. Of the 33 gestational diabeti...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2000.00512.x
更新日期：2000-08-01 00:00:00
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doi：10.1046/j.1440-1754.2000.00548.x
更新日期：2000-12-01 00:00:00
abstract：AIM:The aim of this study is to measure objectively and accurately the physical activity (PA) patterns in Spanish children and adolescents according to their obesity status, gender and age groups. METHODS:A sample of 487 children and 274 adolescents from the European Youth Heart Study participated in the study. The va...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
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更新日期：2013-11-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2006.00903.x
更新日期：2006-07-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2001.00587.x
更新日期：2001-04-01 00:00:00
abstract：:A term infant was admitted at 6 h of age with seizures related to hyponatraemia. During the last hours of labour the infant's mother had drunk 3 L of water. After delivery the serum sodium was 121 mmol/L in the mother and 126 mmol/L in the infant. Both resolved spontaneously. We discuss this case and the impact of mat...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2004.00516.x
更新日期：2004-12-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
doi：10.1111/j.1440-1754.2010.01730.x
更新日期：2012-10-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12292
更新日期：2013-10-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1994.tb00719.x
更新日期：1994-12-01 00:00:00
abstract：AIM:Currently, there are no population-based or hospital-based studies on the full spectrum of paediatric head injuries (HIs) in Australia. We set out to provide detailed information on the incidence rates, causes and clinical management of all severities of HI in children and adolescents at an Australian tertiary refe...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2009.01499.x
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVES:To identify and demonstrate necrotizing dermatitis in infancy; an uncommon, puzzling syndrome, in which anecdotal reporting and personal experience indicates that one third of cases may require skin grafting. Much informed discussion about the pathogenesis of this distressing syndrome centres on the role of ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00531.x
更新日期：2005-01-01 00:00:00
abstract：:Retinopathy of prematurity (ROP) is a multifactorial disease affecting the developing retinal vasculature and remains an important cause of blindness in very preterm infants. Rush disease, or aggressive posterior ROP (AP-ROP), progresses rapidly to stage 5 disease without exhibiting the classical course that includes ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2008.01287.x
更新日期：2008-04-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.13280
更新日期：2017-01-01 00:00:00
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journal_title：Journal of paediatrics and child health
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doi：10.1111/j.1440-1754.1996.tb01538.x
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journal_title：Journal of paediatrics and child health
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更新日期：2011-03-01 00:00:00
abstract：:It is now 50 years since Leo Kanner first described autism as a distinctive pattern of symptoms in some children with severe developmental problems. Since then the assessment and diagnosis of children with pervasive disorders of development has been refined and much is known about the phenomenology and epidemiology. A...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
doi：10.1111/j.1440-1754.1994.tb00590.x
更新日期：1994-04-01 00:00:00
abstract：AIM:Peer review is one component of the improvement of diabetes care delivered by the National Health Service (NHS) in England and Wales. Queensland has a decentralised model of service provision with an established state diabetes network. METHODS:The NHS scheme was adapted for use in Australia, and seven trained revi...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.14281
更新日期：2019-06-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.13645
更新日期：2017-12-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.1999.00373.x
更新日期：1999-08-01 00:00:00
abstract：AIM:Our aim was to identify the clinical features and outcome of multidrug resistant Candida auris (CA) infection in neonates. METHODS:This is a retrospective case cohort study of 17 neonates who developed sepsis caused by CA infection in a tertiary care neonatal intensive care unit over 3 years. The risk factors, cli...
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pub_type： 杂志文章
doi：10.1111/jpc.15019
更新日期：2020-10-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2016-02-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12410
更新日期：2014-01-01 00:00:00
abstract：:Contemporary paediatric practices of Australian Aboriginal men and women, in more than 100 Aboriginal Language Groups, comprise a living discipline whose origins predate Western medicine by tens of millennia. The history of paediatrics acknowledges this surviving continuum of the world's oldest child-care practices. B...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00612.x
更新日期：2005-05-01 00:00:00
abstract：:We describe three infants born to mothers with poorly controlled Graves' disease, who developed transient central hypothyroidism in the immediate postnatal period. Suppression of the fetal pituitary-thyroid axis may be due to placental transfer of thyroxine from the hyperthyroid mother. This may persist for months pos...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00741.x
更新日期：2002-04-01 00:00:00
