Levetiracetam use in critically ill patients.

abstract：BACKGROUND:Hematoma expansion (HE) occurs in approximately one-third of patients with intracerebral hemorrhage (ICH) and is known to be a strong predictor of neurological deterioration as well as poor functional outcome. This study aims to externally validate three risk prediction models of HE (PREDICT, 9-point, and BR...

journal_title：Neurocritical care

authors： Lim JX,Han JX,See AAQ,Lew VH,Chock WT,Ban VF,Pothiawala S,Lim WEH,McAdory LE,James ML,King NKK

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Fever in neurocritical care patients is common and has a negative impact on neurological outcome. The purpose of this prospective observational study was (1) to evaluate the practicability of cooling with newly developed neck pads in the daily setting of neurointensive care unit (NICU) patients and (2) to ev...

journal_title：Neurocritical care

authors： Mink S,Schwarz U,Mudra R,Gugl C,Fröhlich J,Keller E

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Neurocardiogenic injury results from increased sympathetic nervous system activation following acute brain injury. No diagnostic criteria for neurocardiogenic injury exist, and agreement has not been tested. We investigated the agreement by neurointensivists for the presence of neurocardiogenic injury on rou...

journal_title：Neurocritical care

authors： Fletcher JJ,Meurer W,Dunne M,Rajajee V,Jacobs TL,Sheehan KM,Nathan B,Kade AM

更新日期：2014-04-01 00:00:00

abstract：:Subarachnoid hemorrhage (SAH) is a neurological emergency because it may lead to sudden neurological decline and death and, depending on the cause, has treatment options that can return a patient to normal. Because there are interventions that can be life-saving in the first hour of onset, SAH was chosen as an Emergen...

journal_title：Neurocritical care

authors： Edlow JA,Samuels O,Smith WS,Weingart SD

更新日期：2012-09-01 00:00:00

abstract：:The objective of this study was to determine the prevalence of intracranial hypertension (IHT) and the associated mortality rate in patients who suffered from primary intracerebral hemorrhage (ICH). A secondary objective was to assess predisposing factors to IHT development. We conducted a systematic literature search...

journal_title：Neurocritical care

authors： Godoy DA,Núñez-Patiño RA,Zorrilla-Vaca A,Ziai WC,Hemphill JC 3rd

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Infection in the intensive care unit (ICU) empirically requires broad-spectrum antibiotics. Imipenem/cilastatin, often reserved for more serious hospital-acquired infections, is thought to be associated with a higher risk of seizures than other penicillins and carbapenems. We sought to evaluate the safety of...

journal_title：Neurocritical care

authors： Hoffman J,Trimble J,Brophy GM

更新日期：2009-01-01 00:00:00

abstract：:Prophylactic use of hypervolemia and hypertension is believed to present an option to decrease the incidence of symptomatic vasospasm after aneurysmal subarachnoid hemorrhage and improve neurologic outcome. A Medline literature search was conducted to review available evidence regarding volume management after subarac...

journal_title：Neurocritical care

authors： Wolf S,Participants in the International Multi-Disciplinary Consensus Conference on the Critical Care Management of Subarachnoid Hemorrhage.

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Abusive head trauma (AHT) is a common condition in children. Little is known in this condition regarding the frequency of seizures, the factors associated with increased risk of seizures, or the association of seizures with outcome. We sought to determine frequency and risks for in-hospital seizures after AH...

journal_title：Neurocritical care

authors： Goldstein JL,Leonhardt D,Kmytyuk N,Kim F,Wang D,Wainwright MS

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Animal studies suggested that cerebral mitochondrial cardiolipin phospholipids were released after severe traumatic brain injury (TBI), contributing to the pathogenesis of thromboembolism. OBJECTIVES:To determine the incidence of anti-cardiolipin antibodies after severe TBI and whether this was related to t...

journal_title：Neurocritical care

authors： Kalgudi S,Ho KM

更新日期：2020-06-18 00:00:00

abstract：BACKGROUND:Infection is common following stroke and is independently associated with worse outcome. Clinical studies suggest that infections occur more frequently in those individuals with stroke-induced immunologic dysfunction. This study sought to explore the contribution of immunomodulatory cytokines and hormones to...

journal_title：Neurocritical care

authors： Tanzi P,Cain K,Kalil A,Zierath D,Savos A,Gee JM,Shibata D,Hadwin J,Carter K,Becker K

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Hematoma expansion after acute intracerebral hemorrhage occurs most frequently in patients presenting within 3 h of symptom onset. However, the majority of patients present outside this window or with an unknown onset time. We investigated the prevalence of hematoma expansion in these patients and assessed t...

journal_title：Neurocritical care

authors： Brouwers HB,Falcone GJ,McNamara KA,Ayres AM,Oleinik A,Schwab K,Romero JM,Viswanathan A,Greenberg SM,Rosand J,Goldstein JN

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Oral anticoagulants have been associated with greater hematoma expansion in patients with intracerebral hemorrhage (ICH). The purpose of this study was to determine whether the reported use of antiplatelet agents also results in greater hematoma expansion. METHODS:Retrospective review of patients with spont...

journal_title：Neurocritical care

authors： Moussouttas M,Malhotra R,Fernandez L,Maltenfort M,Holowecki M,Delgado J,Lawson N,Badjatia N

更新日期：2010-02-01 00:00:00

abstract：:Multi-modal monitoring has become an integral part of neurointensive care. However, our approach is at this time neither standardized nor backed by data from randomized controlled trials. The goal of the second Neurocritical Care Research Conference was to discuss research priorities in multi-modal monitoring, what re...

journal_title：Neurocritical care

authors： Georgiadis AL,Palesch YY,Zygun D,Hemphill JC 3rd,Robertson CS,Leroux PD,Suarez JI,Second Neurocritical Care Research Conference Investigators.

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Hyponatremia may complicate brain injury and exacerbate cerebral edema and intracranial pressure (ICP). Vasopressin-receptor antagonists (such as conivaptan) are promising novel agents to treat hyponatremia that act by inducing aquaresis. It is unclear whether raising serum sodium in this way could also conf...

journal_title：Neurocritical care

authors： Dhar R,Murphy-Human T

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Delayed ischemic neurological deficits (DINDs) contribute to morbidity and mortality following aneurysmal subarachnoid hemorrhage (SAH). Based on promising preliminary reports, some clinicians routinely administer statins to prevent DINDs. METHODS:Without language restriction, we searched MEDLINE, EMBASE, t...

journal_title：Neurocritical care

authors： Kramer AH,Fletcher JJ

更新日期：2010-04-01 00:00:00

abstract：INTRODUCTION:The incidence of spinal epidural abscesses (SEAs) is rising. Although increased awareness has led to decreased mortality, morbidity remains unacceptably high, with rapid deterioration of neurological status when there is a delay in initiation of treatment. Therefore, we need to build a better understanding...

journal_title：Neurocritical care

authors： Kumar K,Hunter G

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Status, refractory status and super refractory status epilepticus are common neurologic emergencies. The objective of this study is to investigate the feasibility, safety and effectiveness of a ketogenic diet (KD) for refractory status epilepticus (RSE) in adults in the intensive care unit (ICU). METHODS:We...

journal_title：Neurocritical care

authors： Francis BA,Fillenworth J,Gorelick P,Karanec K,Tanner A

更新日期：2019-06-01 00:00:00

abstract：INTRODUCTION:Bacterial meningitis is associated with a high mortality and a high incidence of neurological sequelae. Parainfectious vasculitis leading to ischemic brain damage is a known complication of bacterial meningitis but its treatment is uncertain. METHODS AND RESULTS:We report the case of a 53-year-old man wit...

journal_title：Neurocritical care

authors： Pugin D,Copin JC,Goodyear MC,Landis T,Gasche Y

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Apnea testing is an essential step in the clinical diagnosis of brain death. Current international guidelines recommend placement of an oxygen (O2) insufflation catheter into the endotracheal tube to prevent hypoxemia, but use of a continuous positive airway pressure (CPAP) valve may be more effective at lim...

journal_title：Neurocritical care

authors： Kramer AH,Couillard P,Bader R,Dhillon P,Kutsogiannis DJ,Doig CJ

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The aim of this study is to determine the utility of non-invasive bedside neuromonitoring, including cerebral regional oxygen saturation (rSO2) measured by near-infrared spectroscopy and serum biomarkers, in identifying children at risk from adverse neurological outcome after heart surgery. METHODS:Prospect...

journal_title：Neurocritical care

authors： Sanchez-de-Toledo J,Chrysostomou C,Munoz R,Lichtenstein S,Sao-Avilés CA,Wearden PD,Morell VO,Clark RS,Toney N,Bell MJ

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Release of cardiac biomarkers is reported in patients with subarachnoid hemorrhage (SAH). Data addressing the impact of cardiac injury on outcome in these patients is sparse. This study was conducted to ascertain the association of elevation of serum cardiac Troponin-I (cTnI) with mortality and neurological ...

journal_title：Neurocritical care

authors： Ramappa P,Thatai D,Coplin W,Gellman S,Carhuapoma JR,Quah R,Atkinson B,Marsh JD

更新日期：2008-01-01 00:00:00

abstract：:The presence of pulmonary dysfunction after brain injury is well recognized. Acute lung injury (ALI) occurs in 20% of patients with isolated brain injury and is associated with a poor outcome. The "blast injury" theory, which proposes combined "hydrostatic" and "high permeability" mechanisms for the formation of neuro...

journal_title：Neurocritical care

authors： Mascia L

更新日期：2009-12-01 00:00:00

abstract：INTRODUCTION:The importance of preoperative response to external ventricular drainage (EVD) for treatment of acute hydrocephalus (HCP) following poor grade (Hunt & Hess grade IV or V) aneurysmal subarachnoid hemorrhage (aSAH) has not been clearly defined. The effect of EVD response on preoperative grade and prognosis i...

journal_title：Neurocritical care

authors： Ransom ER,Mocco J,Komotar RJ,Sahni D,Chang J,Hahn DK,Kim GH,Schmidt JM,Sciacca RR,Mayer SA,Connolly ES

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:This study investigated if cerebral blood flow (CBF) regulation by changes of the arterial partial pressure of carbon dioxide (PaCO2) can be used therapeutically to increase CBF and improve neurological outcome after subarachnoid hemorrhage (SAH). METHODS:In 12 mechanically ventilated poor-grade SAH-patient...

journal_title：Neurocritical care

authors： Westermaier T,Stetter C,Kunze E,Willner N,Holzmeier J,Weiland J,Koehler S,Lotz C,Kilgenstein C,Ernestus RI,Roewer N,Muellenbach RM

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Highly asymmetric clinical signs in a patient suggest the need for caution in making the diagnosis of Guillain-Barré Syndrome (GBS). METHODS:Case report and literature review. We present a case of strictly unilateral left third cranial nerve palsy in a patient with GBS, review other highly asymmetrical cran...

journal_title：Neurocritical care

authors： St Louis EK,Jacobson DM

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Case reports suggest lacosamide may have a role in status epilepticus (SE). The purpose of this case series is to describe the use of lacosamide in refractory SE (RSE) at our institution. METHODS:Observational study of all patients admitted to the neurosciences intensive care unit with RSE who received at l...

journal_title：Neurocritical care

authors： Goodwin H,Hinson HE,Shermock KM,Karanjia N,Lewin JJ 3rd

更新日期：2011-06-01 00:00:00

abstract：:A growing body of clinical literature emphasizes the impact of cerebral edema in early brain injury following aneurysmal subarachnoid hemorrhage (aSAH). Aneurysm rupture itself initiates global cerebral edema in up to two thirds of cases. Although cerebral edema is not a universal feature of aSAH, it portends a poor c...

journal_title：Neurocritical care

authors： Hayman EG,Wessell A,Gerzanich V,Sheth KN,Simard JM

更新日期：2017-04-01 00:00:00

abstract：INTRODUCTION:Point-of-care ultrasound of the optic nerve sheath diameter (ONSD) to diagnose increased intracranial pressure (ICP) is of great interest in various clinical scenarios. Yet, the lack of examination standardization has made clinical utility difficult. We compare three ultrasound ocular plane views (inferior...

journal_title：Neurocritical care

authors： Raval R,Shen J,Lau D,Ferguson N,Kelly T,Daniels J,Dorotta I,Ramsingh D

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with acute brain injuries require strict physiologic control to minimize morbidity and mortality. This study aimed to assess in-hospital compliance to strict physiologic parameters (BP, HR, ICP, SpO2) in these populations. METHODS:Patients with severe cerebrovascular events were admitte...

journal_title：Neurocritical care

authors： Porto GB,Spiotta AM,Chalela JA,Kellogg RT,Jauch EC

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Physiological reactions of the stress hormone cortisol include hyperglycemia, hypertension, and endothelium dysfunction. In patients with aneurysmal subarachnoid hemorrhage (SAH), hyperglycemia, hypertension, and endothelium dysfunction are associated with the occurrence of delayed cerebral ischemia (DCI). T...

journal_title：Neurocritical care

authors： Vergouwen MD,van Geloven N,de Haan RJ,Kruyt ND,Vermeulen M,Roos YB

更新日期：2010-06-01 00:00:00